More from Billy Bostickson 🏴👁&👁 🆓
@EricTopol @NBA @StephenKissler @yhgrad B.1.1.7 reveals clearly that SARS-CoV-2 is reverting to its original pre-outbreak condition, i.e. adapted to transgenic hACE2 mice (either Baric's BALB/c ones or others used at WIV labs during chimeric bat coronavirus experiments aimed at developing a pan betacoronavirus vaccine)
@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2
@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj
@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 30, 2021
"we generated a mouse model expressing hACE2 by using CRISPR/Cas9 knockin technology. In comparison with wild-type C57BL/6 mice, both young & aged hACE2 mice sustained high viral loads... pic.twitter.com/j94XtSkscj
@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2
1. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2!
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 2, 2021
2 papers:
Human\u2013viral molecular mimicryhttps://t.co/irfH0Zgrve
Molecular Mimicryhttps://t.co/yLQoUtfS6s https://t.co/lsCv2iMEQz
@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj
@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
"The coronavirus in Italy since September 2019"
Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy
First Published November 11, 2020
https://t.co/nhlccks5AS
Smashed Paywall thanks to @Sci_Hub
https://t.co/wWPFJMjjFJ
Maybe a coincidence but an agreement was recently signed by the authors' institute and guess who?
https://t.co/vh7qX3hyPD
The Lead Author specifically of the paper:
"Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy"
is Giovanni Apolone of the "Fondazione IRCCS Istituto Nazionale Tumori" Milan, Italy
Some funding is involved....
Anyone good at Italian feel free to comment?
"You findee sars cov 2 in old sample back September time, we give you big fat red envelopeee, okey dokey?"
More has emerged regarding the Chinese connection
"Oncology research, Italy and China close to the collaboration protocol"
.https://t.co/Mt5hO9Dggc
Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy
First Published November 11, 2020
https://t.co/nhlccks5AS
Smashed Paywall thanks to @Sci_Hub
https://t.co/wWPFJMjjFJ
Maybe a coincidence but an agreement was recently signed by the authors' institute and guess who?
https://t.co/vh7qX3hyPD
The Lead Author specifically of the paper:
"Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy"
is Giovanni Apolone of the "Fondazione IRCCS Istituto Nazionale Tumori" Milan, Italy
Some funding is involved....
Anyone good at Italian feel free to comment?
"You findee sars cov 2 in old sample back September time, we give you big fat red envelopeee, okey dokey?"
More has emerged regarding the Chinese connection
"Oncology research, Italy and China close to the collaboration protocol"
.https://t.co/Mt5hO9Dggc
Tactics & Direct Action are necessary against Tyrants
"Guerrilla tactics used against the military include assassinations of its officials, bombing military property and sabotaging infrastructure such as telecom towers and
Dr Sasa, spokesperson for the exiled opposition National Unity Government (NUG), said the public had no choice but to defend itself:
"The military are not only destroying our democracy and freedom, but they are destroying every day our dignity as human beings"
It’s do or die”
The residence of coup leader Min Aung Hlaing is a testament to his ambition—and his fear of the people he seeks to rule
https://t.co/yInq583gI5
Apart from Mansion 1, which serves as his official residence, Min Aung Hlaing is known to have several other homes. One is the Yarzathingaha residence in Naypyitaw’s Ottarathiri Township & another is at No.14 Inya Road in Yangon, also properties in Pyin Oo Lwin.
As Myanmar’s most powerful family accumulates vast wealth through military-linked companies like Mytel, the country’s poverty rate will double by next year due to the combined impact of Covid-19 pandemic & the coup.
Nearly half of Myanmar will be living in absolute poverty
"Guerrilla tactics used against the military include assassinations of its officials, bombing military property and sabotaging infrastructure such as telecom towers and
Dr Sasa, spokesperson for the exiled opposition National Unity Government (NUG), said the public had no choice but to defend itself:
"The military are not only destroying our democracy and freedom, but they are destroying every day our dignity as human beings"
It’s do or die”
The residence of coup leader Min Aung Hlaing is a testament to his ambition—and his fear of the people he seeks to rule
https://t.co/yInq583gI5
Apart from Mansion 1, which serves as his official residence, Min Aung Hlaing is known to have several other homes. One is the Yarzathingaha residence in Naypyitaw’s Ottarathiri Township & another is at No.14 Inya Road in Yangon, also properties in Pyin Oo Lwin.
As Myanmar’s most powerful family accumulates vast wealth through military-linked companies like Mytel, the country’s poverty rate will double by next year due to the combined impact of Covid-19 pandemic & the coup.
Nearly half of Myanmar will be living in absolute poverty
More from Tech
On Wednesday, The New York Times published a blockbuster report on the failures of Facebook’s management team during the past three years. It's.... not flattering, to say the least. Here are six follow-up questions that merit more investigation. 1/
1) During the past year, most of the anger at Facebook has been directed at Mark Zuckerberg. The question now is whether Sheryl Sandberg, the executive charged with solving Facebook’s hardest problems, has caused a few too many of her own. 2/ https://t.co/DTsc3g0hQf
2) One of the juiciest sentences in @nytimes’ piece involves a research group called Definers Public Affairs, which Facebook hired to look into the funding of the company’s opposition. What other tech company was paying Definers to smear Apple? 3/ https://t.co/DTsc3g0hQf
3) The leadership of the Democratic Party has, generally, supported Facebook over the years. But as public opinion turns against the company, prominent Democrats have started to turn, too. What will that relationship look like now? 4/
4) According to the @nytimes, Facebook worked to paint its critics as anti-Semitic, while simultaneously working to spread the idea that George Soros was supporting its critics—a classic tactic of anti-Semitic conspiracy theorists. What exactly were they trying to do there? 5/
1) During the past year, most of the anger at Facebook has been directed at Mark Zuckerberg. The question now is whether Sheryl Sandberg, the executive charged with solving Facebook’s hardest problems, has caused a few too many of her own. 2/ https://t.co/DTsc3g0hQf
2) One of the juiciest sentences in @nytimes’ piece involves a research group called Definers Public Affairs, which Facebook hired to look into the funding of the company’s opposition. What other tech company was paying Definers to smear Apple? 3/ https://t.co/DTsc3g0hQf
3) The leadership of the Democratic Party has, generally, supported Facebook over the years. But as public opinion turns against the company, prominent Democrats have started to turn, too. What will that relationship look like now? 4/
4) According to the @nytimes, Facebook worked to paint its critics as anti-Semitic, while simultaneously working to spread the idea that George Soros was supporting its critics—a classic tactic of anti-Semitic conspiracy theorists. What exactly were they trying to do there? 5/
What an amazing presentation! Loved how @ravidharamshi77 brilliantly started off with global macros & capital markets, and then gradually migrated to Indian equities, summing up his thesis for a bull market case!
@MadhusudanKela @VQIndia @sameervq
My key learnings: ⬇️⬇️⬇️
First, the BEAR case:
1. Bitcoin has surpassed all the bubbles of the last 45 years in extent that includes Gold, Nikkei, dotcom bubble.
2. Cyclically adjusted PE ratio for S&P 500 almost at 1929 (The Great Depression) peaks, at highest levels except the dotcom crisis in 2000.
3. World market cap to GDP ratio presently at 124% vs last 5 years average of 92% & last 10 years average of 85%.
US market cap to GDP nearing 200%.
4. Bitcoin (as an asset class) has moved to the 3rd place in terms of price gains in preceding 3 years before peak (900%); 1st was Tulip bubble in 17th century (rising 2200%).
@MadhusudanKela @VQIndia @sameervq
My key learnings: ⬇️⬇️⬇️
Bubble or Bull Market? Join us for a short presentation and candid one on one on 27th Jan, 4pm with Shri \u2066@MadhusudanKela\u2069. \u2066@VQIndia\u2069 \u2066@sameervq\u2069 #bubbleorbullmarket pic.twitter.com/LBvlBrz6mS
— Ravi Dharamshi (@ravidharamshi77) January 24, 2021
First, the BEAR case:
1. Bitcoin has surpassed all the bubbles of the last 45 years in extent that includes Gold, Nikkei, dotcom bubble.
2. Cyclically adjusted PE ratio for S&P 500 almost at 1929 (The Great Depression) peaks, at highest levels except the dotcom crisis in 2000.
3. World market cap to GDP ratio presently at 124% vs last 5 years average of 92% & last 10 years average of 85%.
US market cap to GDP nearing 200%.
4. Bitcoin (as an asset class) has moved to the 3rd place in terms of price gains in preceding 3 years before peak (900%); 1st was Tulip bubble in 17th century (rising 2200%).
