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"The coronavirus in Italy since September 2019"
Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy
First Published November 11, 2020
https://t.co/nhlccks5AS
Smashed Paywall thanks to @Sci_Hub
https://t.co/wWPFJMjjFJ

 Maybe a coincidence but an agreement was recently signed by the authors' institute and guess who?
https://t.co/vh7qX3hyPD
The Lead Author specifically of the paper:
"Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy"
is Giovanni Apolone of the "Fondazione IRCCS Istituto Nazionale Tumori" Milan, Italy
Some funding is involved....
Anyone good at Italian feel free to comment?
"You findee sars cov 2 in old sample back September time, we give you big fat red envelopeee, okey dokey?"

More has emerged regarding the Chinese connection
"Oncology research, Italy and China close to the collaboration protocol"
.https://t.co/Mt5hO9Dggc
Two other authors of the "unexpected" paper are mentioned in the above article
(Ugo Pastorino and Gabriella Sozzi of the National Cancer Institute of Milan)
Finally, the Medical Director herself...
Patrizia Monti leaves the Lecco hospital to take up the position of medical director at the National Cancer Institute of Milan,
https://t.co/k54pfF8kWJ
Her China Connections can be found here:
https://t.co/GwYbXHde4s
and here she is in 2018 having a friendly discussion which laid the basis for future cooperation....
The delegation from the Milan, Italy visited Zhejiang University School of Medicine
http://210.32.0.77/index.php?a=detail&catid=197&id=22906&web=english
Some of the other suthors of the paper work at VisMederi Research Srl, Siena, and also University of Siena but I don't see any special links to China there.....yet
https://t.co/3wst0BIpgM
Linkedin
https://t.co/RayGH6AKHt
and
https://t.co/woRTIo69Lv
Barcelona and Brazil were not enough?
Is this a response to the WHO investigation reports?
WHO knows?
And here we have a more scientific critique from
@BallouxFrancois
https://t.co/XwnOBznLA0
As to be expected the Chinese Media is all over this
https://t.co/tcLHamwfKS
On the pitfalls & dangers of believing new anomalous lab test results which contradict previous findings
(Cross-Reactivity)
Example from Canada in 2003 where results showed SARS but were later found to be due to human CoV-OC43 (HCoV-OC43) cross-reactivity
https://t.co/h8yhefQtlP

More from Billy Bostickson 🏴👁&👁 🆓

Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193
Billy Bostickson 🏴👁&👁 ...
@BillyBostickson
An "Aquarium" needs cleaning in my opinion, but who am I, a mere monkey, to give advice?
Astonished at what @bellingcat discovered about GRU & FSB operations
Skripal https://t.co/PzH3a7JZvy
Navalny https://t.co/eZi63UhWw1
FSB https://t.co/sViYk9RwmB
GRU https://t.co/MY5d5gw2OG


A great post by Ilya Yahin on

Every time Putin talks about “our special services,” his signature smirk appears on his face, and in his words there is poorly concealed bragging
"Of course, we knew everything in advance"
"Yes, we are looking"
"Mercader has already been sent"
“World-class professionals”

Putin clearly loves all these spy games. He is very proud of the special services and therefore endlessly increases budget funding for them.
This is his top priority.
The elderly dictator cannot understand one thing:

there are no effective special services in a state that is completely corroded by corruption. You won't have honest professionals at your fingertips if your son-in-law buys shares of a state company for $ 100, the real value of which exceeds $ 380 million.
ALL , BUSINESS
Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193
Billy Bostickson 🏴👁&👁 ...
@BillyBostickson
1/ Directed Evolution and Serial passage of RNA Viruses
A quick (I hope) thread on RNA viruses & some others, mainly for my own learning process, but also as evidence (as if it was needed) of what modern virology & microbiology is capable of doing to viruses in their laboratories

2/ In Vivo Continuous Directed Evolution
1 Recent advances in the field of in vivo continuous evolution
2 Advances in continuous culture of microbes enable continuous evolution
3 Viruses, prokaryotes, & eukaryotes mediate in vivo continuous evolution
https://t.co/BfR0B2Hwsf


3/ Continuous Directed Evolution of Biomolecules
By greatly accelerating laboratory evolution, PACE may provide solutions to otherwise intractable directed evolution problems and address novel questions about molecular evolution.
https://t.co/G3mIptI54H


4/ CDE for Strain & Protein Engineering
Inducible hypermutator systems accelerate strain evolution without compromising genome integrity.
Site-specific in vivo mutagenesis strategies have facilitated continuous protein engineering.
Automation

5/ Targeted mutagenesis:
A sniper-like diversity generator in microbial engineering
https://t.co/wdKyXghRYe
Advances in the directed evolution of proteins
https://t.co/1xXTtw1i3i
In vivo continuous directed evolution
https://t.co/xKRVSjVvo4
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Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193
Billy Bostickson 🏴👁&👁 ...
@BillyBostickson
November 3 - 9, 2019 -Wuhan Institute of Virology
International Training Course on Biosafety Laboratory Management and Technology
1. Daniel Feakes, head of UN Biological Weapons Convention implementation support agency
2. René Courcol, quality control system expert, France's BSL


List of Lecturers with short bios at
November 3 - 9, WIV Training Course: https://t.co/Bsd9yO40JP
YUAN Zhiming Professor, Wuhan Institute of Virology, CAS (Deputy Director)
SONG Donglin, Professor, Wuhan Institute of Virology, CAS ( Deputy Director of Wuhan BSL-4 Laboratory.)

Dr. TONG Xiao Senior Engineer at WIV (Molecular Virology & (HIV) infection, mechanical & vaccine immunology) On-site Manager & Chief engineer for WIV BSL-4 Lab construction, maintenance & biosafety equipment R&D.

Zhengli Shi, Director of WIV Center for Emerging Infectious Diseases, now in charge of scientific activity in BSL3 & BSL4. Viral pathogen discovery through sequencing techniques, wildlife-borne viral pathogens, particularly bat-borne viruses since 2004.

DENG Fei, Principle Investigator in Research Group on Viruses Resources & Biotechnology in WIV, also Director of Microorganisms & Viruses Resource Center.
Graduate of ECUST, went to Great Lakes Forestry Center, Canada in 2001 & Wageningen University, NL to study baculovirus.
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Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193
Billy Bostickson 🏴👁&👁 ...
@BillyBostickson
1. "Everything starts here, everything disappears from here, & the South China Seafood Market will become clean!"
Interesting Chinese report about the South China Seafood Market & WCDC's pathogen Lab at 288 Machang Road which makes many insinuations yet has not been censored
yet


2. "I'm here for the second time to take samples!" Shi Zhengli, a researcher at the Wuhan Institute of Virology, Chinese Academy of Sciences, appeared at the South China Seafood Market at 17:00 on March 3. On the same day, she and her team took two boxes of samples.


3. Shi Zhengli collects samples from the market to study environmental survival of the coronavirus
"It's not easy to come once" ;)
"Compared with CCDC we have taken much fewer samples, & findings are the same as their results
"They found more than we found, & we found nothing"


4. March the 3rd - 5th - The WCDC "Killing Teams" Arrive


5. "The Thin Lady"
Faced with doubts, on Feb 2, Shi Zhengli declared:
"I, Shi Zhengli, bet my life, it has nothing to do with our laboratory."
Her "statement" was widely questioned.
As of March 3, doubts were still flying, & Zhengli's appearance at the Market was eye-catching.
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Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193
Billy Bostickson 🏴👁&👁 ...
@BillyBostickson
Meat is high in Glycosaminoglycans
(central to coronavirus's ability to attach to host cells)
Beef, pork poultry, seafood are rich in heparan sulfate (glycosaminoglycans), highly charged anchors for SARSCoV2
Meat surfaces critical factors for transmission
https://t.co/yP6lH22OTF

1/5 Science behind that tweet just in case anyone thinks I speak without awareness ;)
Glycosaminoglycans from fresh water fish processing discard - Isolation, structural characterization, and osteogenic activity
https://t.co/fyjac03IuV
SALMON MOUTHS

2/5 Salmon Mouths 2
Characterization of Glycosaminoglycans in Gaping and Intact Connective Tissues of Farmed Atlantic Salmon (Salmo salar) Fillets by Mass

3/5 Why does SARS-COV-2 like meat & seafood?
Glycosaminoglycan binding motif at S1/S2 proteolytic cleavage site on spike glycoprotein may facilitate novel coronavirus (SARS-CoV-2) host cell entry
https://t.co/DpHF1WmxeG
Glycosaminoglycans and

4/5 Glycosaminoglycans
Role of in Infectious Disease
(same authors as above)
https://t.co/3q5dn2Io3Q
Glycosaminoglycans in Infectious Disease
https://t.co/Dep7aJlpLP
Murine Coronavirus with an Extended Host Range Uses Heparan Sulfate as an Entry
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\u0b85\u0bb8\u0bcd\u0ba4\u0bbf\u0ba9\u0bbe\u0baa\u0bc1\u0bb0\u0ba4\u0bcd\u0ba4\u0bc1 \u0b85\u0bb0\u0b9a\u0bbf\U0001f478
அஸ்தினாபுரத்து அரசி👸...
@SivaRoobini555
#தினம்_ஒரு_திருவாசகம்
தொல்லை இரும்பிறவிச் சூழும் தளை நீக்கி
அல்லல் அறுத்து ஆனந்தம் ஆக்கியதே – எல்லை
மருவா நெறியளிக்கும் வாதவூர் எங்கோன்
திருவாசகம் என்னும் தேன்

பொருள்:
1.எப்போது ஆரம்பித்தது என அறியப்படமுடியாத தொலை காலமாக (தொல்லை)

2. இருந்து வரும் (இரும்)


3.பிறவிப் பயணத்திலே ஆழ்த்துகின்ற (பிறவி சூழும்)

4.அறியாமையாகிய இடரை (தளை)

5.அகற்றி (நீக்கி),

6.அதன் விளைவால் சுகதுக்கமெனும் துயரங்கள் விலக (அல்லல் அறுத்து),

7.முழுநிறைவாய்த் தன்னுளே இறைவனை உணர்த்துவதே (ஆனந்த மாக்கியதே),

8.பிறந்து இறக்கும் காலவெளிகளில் (எல்லை)

9.பிணைக்காமல் (மருவா)

10.காக்கும் மெய்யறிவினைத் தருகின்ற (நெறியளிக்கும்),

11.என் தலைவனான மாணிக்க வாசகரின் (வாதவூரெங்கோன்)

12.திருவாசகம் எனும் தேன் (திருவா சகமென்னுந் தேன்)

முதல்வரி: பிறவி என்பது முன்வினை விதையால் முளைப்பதோர் பெருமரம். அந்த ‘முன்வினை’ எங்கு ஆரம்பித்தது எனச் சொல்ல இயலாது. ஆனால் ‘அறியாமை’ ஒன்றே ஆசைக்கும்,, அச்சத்துக்கும் காரணம் என்பதால், அவையே வினைகளை விளைவிப்பன என்பதால், தொடர்ந்து வரும் பிறவிகளுக்கு, ‘அறியாமையே’ காரணம்

அறியாமைக்கு ஆரம்பம் கிடையாது. நமக்கு ஒரு பொருளைப் பற்றிய அறிவு எப்போதிருந்து இல்லை? அதைச் சொல்ல முடியாது. அதனாலேதான் முதலடியில், ஆரம்பமில்லாத அஞ்ஞானத்தை பிறவிகளுக்குக் காரணமாகச் சொல்லியது. ஆனால் அறியாமை, அறிவின் எழுச்சியால், அப்போதே முடிந்து விடும்.
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Jaya_Upadhyaya
Jaya_Upadhyaya
@Jayalko1
MEENAKSHI AMMAN, MADURAI (TN)
#bharatmandir #navratri2021

A paadal Petra sthalam where Shiva took the form of Sundareswarar (the handsome one) and married Devi Parvati (Meenakshi).
Devi is also known by the name Angayarkanni (mother with the beautiful fish eyes).
@GunduHuDuGa


Devi Meenakshi emerged from yagna fire as a 3 year old girl when Pandyan King Malayadwaja and Kanchanamalai were praying for a child.
It is said that Devi was born with three breasts and there was a prophesy that her superfluous breast would melt away when she met her husband.


Devi ruled over Madurai and captured Indralok. She went on to capture Kailasha. When she saw Shiva, her 3rd breast disappeared and she realised that Shiva would be her consort.
The divine marriage was attended by all Devas and Sri Vishnu (as her brother) gave her hand to Shiva.


It is said that Indra found a swayambhu lingam at Kadamba Vanam. He placed it in Madurai where the kshetram stands. Here, Shiva is seen on the vehicle of Indra.
The Golden Lotus Tank is said to be the place where a golden lotus blossomed for the puja performed by Indra.


The Meenakshi Thirukalyanam festival is celebrated in the Chithirai month to mark the divine marriage of Meenakshi Amman. The festival includes a procession where Meenakshi and Sundareshwara travel in a chariot and Sri Vishnu gives away his sister in marriage to Shiva.
ALL
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Ankur Patel
Ankur Patel
@AnkurPatel59
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TRADING SCREENERS , TRADING SCREENER , ALL
Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193
Billy Bostickson 🏴👁&👁 ...
@BillyBostickson
1. Mini Thread on Conflicts of Interest involving the authors of the Nature Toilet Paper:
https://t.co/VUYbsKGncx
Kristian G. Andersen
Andrew Rambaut
Ian Lipkin
Edward C. Holmes
Robert F. Garry

2. Thanks to @newboxer007 for forwarding the link to the research by an Australian in Taiwan (not on

3. K.Andersen didn't mention "competing interests"
Only Garry listed Zalgen Labs, which we will look at later.
In acknowledgements, Michael Farzan, Wellcome Trust, NIH, ERC & ARC are mentioned.
Author affiliations listed as usual.
Note the 328 Citations!
https://t.co/nmOeohM89Q


4. Kristian Andersen (1)
Andersen worked with USAMRIID & Fort Detrick scientists on research, with Robert Garry, Jens Kuhn & Sina Bavari among


5. Kristian Andersen (2)
Works at Scripps Research Institute, which WAS in serious financial trouble, haemorrhaging 20 million $ a year.
But just when the first virus cases were emerging, they received great news.
They issued a press release dated November 27, 2019:
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Angela Jamison
Angela Jamison
@AnJamison
@SethAbramson @buzz\_chronicles @buzz\\\_chronicles @buzz_chronicles save as category @pdfmakerapp grab @pdfmakerapp grab this @readwiseio save @readwiseio save thread @threader compile summarize @Threadreaderapp unroll please @ttttreads unroll @unrollthread.com @SaveToBookmarks
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Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193
Billy Bostickson 🏴👁&👁 ...
@BillyBostickson
Tip from the Monkey
Pangolins, September 2019 and PLA are the key to this mystery
Stay Tuned!


1. Yang


2. A jacobin capuchin dangling a flagellin pangolin on a javelin while playing a mandolin and strangling a mannequin on a paladin's palanquin, said Saladin
More to come tomorrow!


3. Yigang Tong
https://t.co/CYtqYorhzH
Archived: https://t.co/ncz5ruwE2W


4. YT Interview
Some bats & pangolins carry viruses related with SARS-CoV-2, found in SE Asia and in Yunnan, & the pangolins carrying SARS-CoV-2 related viruses were smuggled from SE Asia, so there is a possibility that SARS-CoV-2 were coming from
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Dr Catherine Pemble is #SocialDistancing
Dr Catherine Pemble is...
@CatherinePemble
Right, screw it. Here's a thread on *that* FBLive by Alex Cairnie about #Govanhill. Lets do a watch-through shall we? (Mind, I'm a resident of Govanhill, and a sociologist. I'm also 5'3, and a visibly queer woman so if half his claims are true I should be living in terror)

00:30: Welcomes viewers and uses points out that his videos are only getting attention b/c they're 'horrific'. Directs folk to his Youtube page. So already clout hunting.

1:08: "I've been warned to stay out of Govanhill. I'm a marked man" (proceeds to use a beanie as a disguise)

1:30 "Laughing and joking aside, here's somebodys front garden." Proceeds to show litter and claim its thrown from windows and this is 'common'. I know a handful of streets with litter issues like this, but its neither common nor unique to #govanhill and other deprived areas.

2:10 "Don't be under any illusion I'm only showing you the bad bits" - only shows you the bad bits.

3:45: He's had offers of help, but hes said no because hes not responsible for 'anybody elses safety' Good lord.

5:01: "Its not that bad. But its not all good either" -Correct

6:00: TW: child abuse - He starts claiming to have been contacted by a health professional and told about child abuse 'in the area'. Huge ethical issues here as the 'professional' who has 'been in the game a long time' is reporting to Facebook Dude and not authorities.
HEALTH
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Anu Satheesh \U0001f1ee\U0001f1f3
Anu Satheesh 🇮🇳...
@AnuSatheesh5
Stories of Guruvayurappan
Shri Krishna Leela

This is a beautiful story of Guruvayurappan. Once there lived in Guruvayur a poor family. Kitta, his wife & kids were struggling for their daily needs. With only a coconut tree in house, he earned a living by selling coconuts.


Kitta was from a low caste family. He was a great devotee of Guruvayurappan. Everyday before going to work he always prayed infront of a picture of Guruvayurappan in his house. His only wish was to worship at Guruvayur & have annadanam in temple. But he was not allowed there


It was Utsavam time in Guruvayur. From far behind kitta and family worshipped Guruvayurappan. Annadanam was given daily and no one was left empty stomach. Only Kitta didn't receive. That night, it was only Kitta's family who was sleeping without food. After temple nada closed


Shri Krishna, dressed himself as a Brahmin went to temple Kitchen. He packed food and went directly to kitta's house. Reaching Kitta's house, Shri Krishna told he was sent by a cook of Guruvayur temple and gave them the food he packed. Kitta and family was very happy seeing food.


When Kitta finished his food, Brahmin asked it will be better if he get a tender coconut( karikku)to drink. Kitta climbed the tree and gave all coconuts to him. After having 1 tender coconut, the Brahmin asked to bring remaining coconuts to Guruvayur temple the next day.
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foone
foone
@Foone
I got a Toshiba T1200, which has a bad screen, and a dead CMOS battery, and I thought the hard drive was broken too...


but I rebooted it and heard a KTHUNK and a really loud spin-up noise and holy shit, the hard drive works!


and it still has files on it. the newest date is January 1994.


It's a 21mb hard drive, with ~37k of bad sectors.

This fucker is never going to spin up again, so I better go find some serial cables and copy shit off now.


The backlight is fucked so I'm shining a flashlight on it.
without it, it looks like this.
TECH
Noah Smith
Noah Smith
@Noahpinion
Remember: Just because an idea is old doesn't mean it's good.

Knowing whether old ideas are more likely to be good requires understanding whether conditions have changed in important ways.

Horse archery was an amazing method of warfare for over a thousand years...then people invented guns, and suddenly this great idea that had stood the test of time became obsolete.

Then again, when underlying conditions don't change much, tried-and-true approaches are probably better.

"Learning the lessons of history" usually just means assuming ergodicity and stationarity in an informal time-series model...

(end)
SOCIETY