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I want to break down Lindsey's letter, because it is breathtakingly hypocritical and stoking division with every sentence, despite claiming to be concerned with healing.


1) "But now, in your first act as Majority Leader, rather than begin the national healing that the country so desperately yearns for, you seek vengeance and political retaliation instead."

Trump incited an attack on the Capitol, on Congress, and on a free & fair election.

Trump has yet to concede, to apologize, or to admit he was lying about the outcome of the election. He has done nothing that demonstrates he does not continue to present a danger to our nation.

Trump's supporters continue to conspire to overthrow the government--with Trump's implicit, and quite possibly explicit--support. At this very moment, over 20,000 troops are stationed in our nation's capital to ensure the inauguration of President-Elect Biden can be completed.

It is not "vengeance" or "political retaliation" to insist a man that has fomented and continues to inspire a violent insurrection against the government is unfit ever to hold office again.

This is, in fact, a bare minimum protection for our country against future harm by Trump.
My thoughts on 1-dose vs 2-dose approach.

TL; DR

Wrong questions give you wrong answers.

We assuredly should want 2 doses, the only issue is the timing of 2nd dose. And a brief delay is a risk worth taking.

But let's prioritize >65 year old 2nd doses at same time.

1/9


First, let's start with @VirusesImmunity brilliant thread:

We know enough to know that there is vast benefit from giving substantial immunity to as many as possible as quickly as possible.


We also know that the timing of second dose was never set in stone. Pfizer chose to give second dose at 19-23 days; Moderna chose at 28-31 days. They tested at these levels and proved safety and efficacy. Safety is not at issue with delayed dosing. Efficacy probably is.

3/9

Most of medicine, as practiced, has not been subjected to rigorous clinical trials for various reasons. We weigh available evidence & act accordingly. We pivot when new evidence is available. We should want more RCTs, but they are often unethical or impossible to perform. 4/9

Ideally, Pfizer &/or Moderna would have already done a single dose arm. JNJ is testing both a single-dose & 2-dose regimen. We will have some data in a few weeks on the 1-dose regimen.

But we don't live in an ideal world. We live in the real world.