1. Brian Fung works for CNN. I will share with you some of his recent tweets and his family. ((thread))
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Today's Twitter threads (a Twitter thread).
Inside: Planet Money on HP's myriad ripoffs; Strength in numbers; and more!
Archived at: https://t.co/esjoT3u5Gr
#Pluralistic
1/
On Feb 22, I'm delivering a keynote address for the NISO Plus conference, "The day of the comet: what trustbusting means for digital manipulation."
https://t.co/Z84xicXhGg
2/
Planet Money on HP's myriad ripoffs: Ink-stained wretches of the world, unite!
https://t.co/k5ASdVUrC2
3/
Strength in numbers: The crisis in accounting.
https://t.co/DjfAfHWpNN
4/
#15yrsago Bad Samaritan family won’t return found expensive camera https://t.co/Rn9E5R1gtV
#10yrsago What does Libyan revolution mean for https://t.co/Jz28qHVhrV? https://t.co/dN1e4MxU4r
5/
Inside: Planet Money on HP's myriad ripoffs; Strength in numbers; and more!
Archived at: https://t.co/esjoT3u5Gr
#Pluralistic
1/
On Feb 22, I'm delivering a keynote address for the NISO Plus conference, "The day of the comet: what trustbusting means for digital manipulation."
https://t.co/Z84xicXhGg
2/
Planet Money on HP's myriad ripoffs: Ink-stained wretches of the world, unite!
https://t.co/k5ASdVUrC2
3/
Back in November, I published an article for @EFF about @HP's latest printer-ink ripoff: after offering its customers a free-ink-for-life plan, it unilaterally switched them all to a $1/month-for-life plan.https://t.co/bsc73xPSuo
— Cory Doctorow #BLM (@doctorow) February 18, 2021
1/ pic.twitter.com/tagduPupA5
Strength in numbers: The crisis in accounting.
https://t.co/DjfAfHWpNN
4/
Accountancy is more likely to be mocked than celebrated (or condemned), but accountants, far more than poets, are the unacknowledged legislators of the world.
— Cory Doctorow #BLM (@doctorow) February 18, 2021
1/ pic.twitter.com/FaNQc66gQN
#15yrsago Bad Samaritan family won’t return found expensive camera https://t.co/Rn9E5R1gtV
#10yrsago What does Libyan revolution mean for https://t.co/Jz28qHVhrV? https://t.co/dN1e4MxU4r
5/
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Keep dwelling on this:
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs