2/20
Happy Tuesday! The latest focal S:N501 build is now updated with sequences from 11 Jan.
There are 101 new sequences in the 501Y.V1 (B.1.1.7 #b117) & 501Y.V2 variants.
Additionally, I'll include some updates on S:E484K in this thread.
1/20
https://t.co/dXx6nk6Llz
2/20
3/20
4/20
6/20
7/20
Zooming in, the new sequences are marked in red: 2 are separate introductions. Zooming in further (divergence view), cluster at the top are identical to an older sequence.
8/20
9/20
10/20
11/20
There are 4 new non-South African sequences in 501Y.V2, including the first from Ireland (3) and the Netherlands (1).
12/20
The Netherlands has its first sequence in 501Y.V2 (picture 3).
13/20
14/20
https://t.co/c7wlQOLRiq
S:E484K is found predominantly in the 501Y.V2 variant, & in a cluster of sequences primarily in Brazil, though it has appeared numerous times in the past.
15/20
https://t.co/Od95D6DL74
Links to the studies are on https://t.co/SmanZBHpse
16/20
Translated report linked below.
17/20
https://t.co/G1ITeT3MoV
Additionally, I've added a *temporary* label to the Brazilian cluster with S:E484K: 20B/S.484K.
18/20
19/20
Help make my updates more boring: bring cases down!
20/20
https://t.co/fZDQqwvJmr
21/20
Updated SARS-CoV-2 new variant report now available for 2021-01-11 at https://t.co/e3J9becNTz. @arambaut @viralverity @MOUGK pic.twitter.com/x4UabXv5Yt
— \xc1ine O'Toole (@AineToole) January 11, 2021
More from Dr Emma Hodcroft
More from For later read
This response to my tweet is a common objection to targeted advertising.
@KevinCoates correct me if I'm wrong, but basic point seems to be that banning targeted ads will lower platform profits, but will mostly be beneficial for consumers.
Some counterpoints 👇
1) This assumes that consumers prefer contextual ads to targeted ones.
This does not seem self-evident to me
Research also finds that firms choose between ad. targeting vs. obtrusiveness 👇
If true, the right question is not whether consumers prefer contextual ads to targeted ones. But whether they prefer *more* contextual ads vs *fewer* targeted
2) True, many inframarginal platforms might simply shift to contextual ads.
But some might already be almost indifferent between direct & indirect monetization.
Hard to imagine that *none* of them will respond to reduced ad revenue with actual fees.
3) Policy debate seems to be moving from:
"Consumers are insufficiently informed to decide how they share their data."
To
"No one in their right mind would agree to highly targeted ads (e.g., those that mix data from multiple sources)."
IMO the latter statement is incorrect.
@KevinCoates correct me if I'm wrong, but basic point seems to be that banning targeted ads will lower platform profits, but will mostly be beneficial for consumers.
Some counterpoints 👇
That targeted ads allow for "free" products for consumers is a common talking point and we're going to see more of it in the coming months.: https://t.co/Xty3My3f0u (1/14)
— Kevin Coates (@KevinCoates) February 16, 2021
1) This assumes that consumers prefer contextual ads to targeted ones.
This does not seem self-evident to me
Great post by @Sherman1890 got me thinking about the future of targeted ads.
— Dirk Auer (@AuerDirk) February 12, 2021
More and more tools (privacy labels, ad blockers, GDPR) enable consumers to opt-out from targeted ads - can limit the data platforms receive or block ads altogether.
The end of targeted ads? \U0001f9f5\U0001f447 https://t.co/MA6A3BrUWq
Research also finds that firms choose between ad. targeting vs. obtrusiveness 👇
If true, the right question is not whether consumers prefer contextual ads to targeted ones. But whether they prefer *more* contextual ads vs *fewer* targeted
2) True, many inframarginal platforms might simply shift to contextual ads.
But some might already be almost indifferent between direct & indirect monetization.
Hard to imagine that *none* of them will respond to reduced ad revenue with actual fees.
3) Policy debate seems to be moving from:
"Consumers are insufficiently informed to decide how they share their data."
To
"No one in their right mind would agree to highly targeted ads (e.g., those that mix data from multiple sources)."
IMO the latter statement is incorrect.
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THE MEANING, SIGNIFICANCE AND HISTORY OF SWASTIK
The Swastik is a geometrical figure and an ancient religious icon. Swastik has been Sanatan Dharma’s symbol of auspiciousness – mangalya since time immemorial.
The name swastika comes from Sanskrit (Devanagari: स्वस्तिक, pronounced: swastik) &denotes “conducive to wellbeing or auspicious”.
The word Swastik has a definite etymological origin in Sanskrit. It is derived from the roots su – meaning “well or auspicious” & as meaning “being”.
"सु अस्ति येन तत स्वस्तिकं"
Swastik is de symbol through which everything auspicios occurs
Scholars believe word’s origin in Vedas,known as Swasti mantra;
"🕉स्वस्ति ना इन्द्रो वृधश्रवाहा
स्वस्ति ना पूषा विश्ववेदाहा
स्वस्तिनास्तरक्ष्यो अरिश्तनेमिही
स्वस्तिनो बृहस्पतिर्दधातु"
It translates to," O famed Indra, redeem us. O Pusha, the beholder of all knowledge, redeem us. Redeem us O Garudji, of limitless speed and O Bruhaspati, redeem us".
SWASTIK’s COSMIC ORIGIN
The Swastika represents the living creation in the whole Cosmos.
Hindu astronomers divide the ecliptic circle of cosmos in 27 divisions called https://t.co/sLeuV1R2eQ this manner a cross forms in 4 directions in the celestial sky. At centre of this cross is Dhruva(Polestar). In a line from Dhruva, the stars known as Saptarishi can be observed.
The Swastik is a geometrical figure and an ancient religious icon. Swastik has been Sanatan Dharma’s symbol of auspiciousness – mangalya since time immemorial.
The name swastika comes from Sanskrit (Devanagari: स्वस्तिक, pronounced: swastik) &denotes “conducive to wellbeing or auspicious”.
The word Swastik has a definite etymological origin in Sanskrit. It is derived from the roots su – meaning “well or auspicious” & as meaning “being”.
"सु अस्ति येन तत स्वस्तिकं"
Swastik is de symbol through which everything auspicios occurs
Scholars believe word’s origin in Vedas,known as Swasti mantra;
"🕉स्वस्ति ना इन्द्रो वृधश्रवाहा
स्वस्ति ना पूषा विश्ववेदाहा
स्वस्तिनास्तरक्ष्यो अरिश्तनेमिही
स्वस्तिनो बृहस्पतिर्दधातु"
It translates to," O famed Indra, redeem us. O Pusha, the beholder of all knowledge, redeem us. Redeem us O Garudji, of limitless speed and O Bruhaspati, redeem us".
SWASTIK’s COSMIC ORIGIN
The Swastika represents the living creation in the whole Cosmos.
Hindu astronomers divide the ecliptic circle of cosmos in 27 divisions called https://t.co/sLeuV1R2eQ this manner a cross forms in 4 directions in the celestial sky. At centre of this cross is Dhruva(Polestar). In a line from Dhruva, the stars known as Saptarishi can be observed.
![Peter McCormack [Jan/3\u279e\u20bf \U0001f511\u220e]](https://pbs.twimg.com/profile_images/1524287442307723265/_59ITDbJ_normal.jpg)
"I really want to break into Product Management"
make products.
"If only someone would tell me how I can get a startup to notice me."
Make Products.
"I guess it's impossible and I'll never break into the industry."
MAKE PRODUCTS.
Courtesy of @edbrisson's wonderful thread on breaking into comics – https://t.co/TgNblNSCBj – here is why the same applies to Product Management, too.
There is no better way of learning the craft of product, or proving your potential to employers, than just doing it.
You do not need anybody's permission. We don't have diplomas, nor doctorates. We can barely agree on a single standard of what a Product Manager is supposed to do.
But – there is at least one blindingly obvious industry consensus – a Product Manager makes Products.
And they don't need to be kept at the exact right temperature, given endless resource, or carefully protected in order to do this.
They find their own way.
make products.
"If only someone would tell me how I can get a startup to notice me."
Make Products.
"I guess it's impossible and I'll never break into the industry."
MAKE PRODUCTS.
Courtesy of @edbrisson's wonderful thread on breaking into comics – https://t.co/TgNblNSCBj – here is why the same applies to Product Management, too.
"I really want to break into comics"
— Ed Brisson (@edbrisson) December 4, 2018
make comics.
"If only someone would tell me how I can get an editor to notice me."
Make Comics.
"I guess it's impossible and I'll never break into the industry."
MAKE COMICS.
There is no better way of learning the craft of product, or proving your potential to employers, than just doing it.
You do not need anybody's permission. We don't have diplomas, nor doctorates. We can barely agree on a single standard of what a Product Manager is supposed to do.
But – there is at least one blindingly obvious industry consensus – a Product Manager makes Products.
And they don't need to be kept at the exact right temperature, given endless resource, or carefully protected in order to do this.
They find their own way.