2/14
A brief update to the focal S:N501 builds to start your Friday off right! This one includes data from 7 Jan 21.
We have about 20 new sequences each in 501Y.V1 (B.1.1.7 #b117) & 501Y.V2.
Let's take a look at the new sequences, starting with 501Y.V1
1/14
https://t.co/kT1gFsSZn0
2/14
3/14
Zooming in (divergence view), we can see 2 new sequences are identical (possible local transmission), & 2 differ by 2 mutations (1 each).
4/14
5/14
6/14
Zooming in (divergence view), we can see it is identical to 2 older sequences, which may indicate local transmission or a common exposure.
7/14
(UK data may be affected by subsampling due to large sequence numbers.)
8/14
These are a mix of separate introductions & local transmission.
Connections to French sequences are in the next tweet...
9/14
They are related to seqs from England, but whether this is European transmission or exposure to common diversity in S Africa can't be distinguished clearly.
10/14
The other 5 cluster together, but are separated by a 1-3 mutations. This could indicate local transmission or transmission from unsampled South African diversity.
11/14
Remember: many countries are currently focusing sequencing efforts on S:N501 variants, so frequencies are often not true representations of the 501Y variants.
13/14
https://t.co/c7wlQOLRiq
More from Dr Emma Hodcroft
Each day brings new challenges, but here's an update to the dedicated S.N501 build, using data from 6 Jan 2021 to keep you going.
There are 42 new non-UK sequences in 501Y.V1 (B.1.1.7) & 7 new non-South-African sequences in 501Y.V2.
1/14
https://t.co/kT1gFsSZn0
There are 42 new non-UK sequences in 501Y.V1 from the Netherlands, Italy, Hong Kong, Finland, Sweden, Germany, USA, Switzerland, Brazil, and the first sequence from 501Y.V1 in Oman.
https://t.co/XA8VR8HiEq
2/14
Oman has their first sequence which falls into 501Y.V1:
3/14
Finland has 12 new sequences (orange), which mostly represent separate introductions. Zooming in (divergence view), we can see 3 of the new sequences are identical (red), which may indicate the cases are connected.
4/14
Sweden has 8 new sequences (orange), which indicate separate introductions.
5/14
There are 42 new non-UK sequences in 501Y.V1 (B.1.1.7) & 7 new non-South-African sequences in 501Y.V2.
1/14
https://t.co/kT1gFsSZn0
There are 42 new non-UK sequences in 501Y.V1 from the Netherlands, Italy, Hong Kong, Finland, Sweden, Germany, USA, Switzerland, Brazil, and the first sequence from 501Y.V1 in Oman.
https://t.co/XA8VR8HiEq
2/14
Oman has their first sequence which falls into 501Y.V1:
3/14
Finland has 12 new sequences (orange), which mostly represent separate introductions. Zooming in (divergence view), we can see 3 of the new sequences are identical (red), which may indicate the cases are connected.
4/14
Sweden has 8 new sequences (orange), which indicate separate introductions.
5/14
More from For later read
(1/50)
#Cardano “Understanding Kamali”
#Cardano will be the underpinning of the emergence of Africa.
To grasp the full weight of the SOLUTIONS #Cardano can provide it is pertinent to read “Understanding Africa” as I will draw directly from the PROBLEMS laid out.
(2/50)
Here is a link if you have not already read
(3/50)
What I will attempt to do here, is to create an immersive world for you to be placed in to grasp the weight and size of problems from the ground level and then take a grass-roots approach at solving them using #Cardano and its technology.
(4/50)
As an investor and community member of #Cardano, this should be extremely important to you as you have a stake (pun intended) in this.
“You are paid in direct proportion to the difficulty of the problems you solve” - @elonmusk
(5/50)
In Africa, agribusiness, more than any other sector, has the potential to reduce poverty and drive economic growth. Agriculture accounts for nearly half of the continent’s gross domestic product and employs 60 percent of the labor force.
#Cardano “Understanding Kamali”
#Cardano will be the underpinning of the emergence of Africa.
To grasp the full weight of the SOLUTIONS #Cardano can provide it is pertinent to read “Understanding Africa” as I will draw directly from the PROBLEMS laid out.
(2/50)
Here is a link if you have not already read
(1/38) #Cardano \u201cUnderstanding Africa\u201d (Part 1 of 2)
— FatCat (@fatcatofcrypto) February 10, 2021
This thread will be split into two parts with the 2nd coming out on Sunday.
Part 1 will layout the pervasive PROBLEMS Africa faces whereas Part 2 will apply direct technologies @InputOutputHK can implement as SOLUTIONS. pic.twitter.com/n3I91bnddq
(3/50)
What I will attempt to do here, is to create an immersive world for you to be placed in to grasp the weight and size of problems from the ground level and then take a grass-roots approach at solving them using #Cardano and its technology.
(4/50)
As an investor and community member of #Cardano, this should be extremely important to you as you have a stake (pun intended) in this.
“You are paid in direct proportion to the difficulty of the problems you solve” - @elonmusk
(5/50)
In Africa, agribusiness, more than any other sector, has the potential to reduce poverty and drive economic growth. Agriculture accounts for nearly half of the continent’s gross domestic product and employs 60 percent of the labor force.
