BillyBostickson's Categories
BillyBostickson's Authors
Latest Saves
[Thread] Wang et al. (2021):
Another article revealing trips to the Mojiang mine and Laos was kept in the limbo when the pandemic started.
Note: The article covers HKU10 viruses which are not related with SARS-like
It was "received" by the journal on 30 July 2021, but the sequences were accessioned in Genbank on 17-SEP-2019.
So it seems that this article may have prior rejections or have been withdrawn from other journals.
https://t.co/laNmTabCuk
One of the samples is 4996 (note that RaTG13 = 4991).
There is a small discrepancy: 4991 was collected on 24-Jul-13 but this one on 21-Jul-13.
4996 is 100% identical to MJ_67C (from HKU team when they went to Mojiang) and clusters with 3723 (Mojiang).
https://t.co/XqMEyEi45T
Btw, 3740 (Mojiang) and 7345 also cluster together, supporting that 7345 is from Tongguan/Mojiang as we already deduced a year
The article does not explicitly say they collected samples from Mojiang, although the low-res map confirms it.
Another article revealing trips to the Mojiang mine and Laos was kept in the limbo when the pandemic started.
Note: The article covers HKU10 viruses which are not related with SARS-like
It was "received" by the journal on 30 July 2021, but the sequences were accessioned in Genbank on 17-SEP-2019.
So it seems that this article may have prior rejections or have been withdrawn from other journals.
https://t.co/laNmTabCuk
One of the samples is 4996 (note that RaTG13 = 4991).
There is a small discrepancy: 4991 was collected on 24-Jul-13 but this one on 21-Jul-13.
4996 is 100% identical to MJ_67C (from HKU team when they went to Mojiang) and clusters with 3723 (Mojiang).
https://t.co/XqMEyEi45T
Btw, 3740 (Mojiang) and 7345 also cluster together, supporting that 7345 is from Tongguan/Mojiang as we already deduced a year
- Timeline of relevant visits to Yunnan for 2012-2015
— Francisco de Asis (@franciscodeasis) November 28, 2020
- Probable samples from the mineshaft for 2014-2015 (detail and summary) pic.twitter.com/wNf3rWDCtQ
The article does not explicitly say they collected samples from Mojiang, although the low-res map confirms it.
How SARS2 was stitched together
Nowadays,SARS2 like viruses can be generated in lab within weeks https://t.co/uWAI0oMrIU
If this was possible in Wuhan 2018/19 is debatable.
However, Shi Zhengli had 2 grants to investigate which manipulations enable bat viruses to go pandemic.
1/x
This was pointed before by members of DRASTIC https://t.co/By9hljwjuY, @TheSeeker268 @ydeigin
CV: https://t.co/fXlqRIJoWO
Let's say the WIV did not have yeast artificial cromosomes yet, they would have had to rely on bacteria as described here:
https://t.co/F4C9HfVcXv
2/x
This method has now evolved using in vitro assembly and transcription, which significantly speeds up the process and reduces costs, as described here:
https://t.co/Qi180L3c9u
In either case, one would need a special kind of Type IIS endonucleases (DNA cleaving enzymes):
3/x
These relatively rare enzymes cut outside of their recognition site and can produce variable 4 nucleotide long DNA sticky ends. Different sticky ends enable an ordered assembly of the full viral genome by ensuring that always the right ends are stitched together by ligases.
4/x
Also, there should be not too many fragments, and fragments should not be longer than ~8 thousand bases.
All these parameters, that do not have any advantage in natural evolution, are miraculously also met by SARS2.
This backbone also enables super easy RBM/FCS manipulations.
5/x
Nowadays,SARS2 like viruses can be generated in lab within weeks https://t.co/uWAI0oMrIU
If this was possible in Wuhan 2018/19 is debatable.
However, Shi Zhengli had 2 grants to investigate which manipulations enable bat viruses to go pandemic.
1/x
This was pointed before by members of DRASTIC https://t.co/By9hljwjuY, @TheSeeker268 @ydeigin
CV: https://t.co/fXlqRIJoWO
Let's say the WIV did not have yeast artificial cromosomes yet, they would have had to rely on bacteria as described here:
https://t.co/F4C9HfVcXv
2/x
This method has now evolved using in vitro assembly and transcription, which significantly speeds up the process and reduces costs, as described here:
https://t.co/Qi180L3c9u
In either case, one would need a special kind of Type IIS endonucleases (DNA cleaving enzymes):
3/x
These relatively rare enzymes cut outside of their recognition site and can produce variable 4 nucleotide long DNA sticky ends. Different sticky ends enable an ordered assembly of the full viral genome by ensuring that always the right ends are stitched together by ligases.
4/x
Also, there should be not too many fragments, and fragments should not be longer than ~8 thousand bases.
All these parameters, that do not have any advantage in natural evolution, are miraculously also met by SARS2.
This backbone also enables super easy RBM/FCS manipulations.
5/x
Evidence of Genetic Engineering of SARS-COV-2. Part 2 (thread).
The Outlandish Case of the Uncanny HIV Inserts.
Part 1 is below if you haven't yet read it:
https://t.co/CeztISvFQN
Early on in the pandemic a group of Indian HIV researchers announced they had found fragments of HIV in the SARS-COV-2 genome. While each fragment was small, they *rightly* stated that finding them all together was no coincidence.
https://t.co/vlAXv8UOKC
For their efforts they were slammed by other scientists and media, and on Feb 2, 2019, the day after the Fauci teleconference with Holmes, Andersen, Farrar et al, they withdrew their pre-print.
One of those sequences will be very familiar to anyone who has been following the story carefully. Although there has been a deletion within, Insert 4 is an easily recognizable part of the sequence around the SARS-COV-2 S1/S2 junction - QTNSPRRA.
It seems that these sequences have been taken from HIV and inserted into SARS-COV-2 genome. But what are their purpose? And did they originate in HIV naturally, or are they also artificial origin?
The FCS sequence I said previously derives from N. Meningitidis. Was I wrong?
The Outlandish Case of the Uncanny HIV Inserts.
Part 1 is below if you haven't yet read it:
https://t.co/CeztISvFQN
Evidence of genetic engineering in SARS-COV- Thread
— Dog's Breakfast (@breakfast_dogs) November 7, 2021
While the "lab leak" theory of SARS-COV-2 is now acceptable, many scientists still claim there's no evidence that SARS-COV-2 was genetically engineered.
These scientists either haven't looked, or need their eyes checked... pic.twitter.com/Bzz3XcW48t
Early on in the pandemic a group of Indian HIV researchers announced they had found fragments of HIV in the SARS-COV-2 genome. While each fragment was small, they *rightly* stated that finding them all together was no coincidence.
https://t.co/vlAXv8UOKC
For their efforts they were slammed by other scientists and media, and on Feb 2, 2019, the day after the Fauci teleconference with Holmes, Andersen, Farrar et al, they withdrew their pre-print.
One of those sequences will be very familiar to anyone who has been following the story carefully. Although there has been a deletion within, Insert 4 is an easily recognizable part of the sequence around the SARS-COV-2 S1/S2 junction - QTNSPRRA.
It seems that these sequences have been taken from HIV and inserted into SARS-COV-2 genome. But what are their purpose? And did they originate in HIV naturally, or are they also artificial origin?
The FCS sequence I said previously derives from N. Meningitidis. Was I wrong?
@franciscodeasis https://t.co/OuQaBRFPu7
Unfortunately the "This work includes the identification of viral sequences in bat samples, and has resulted in the isolation of three bat SARS-related coronaviruses that are now used as reagents to test therapeutics and vaccines." were BEFORE the
chimeric infectious clone grants were there.https://t.co/DAArwFkz6v is in 2017, Rs4231.
https://t.co/UgXygDjYbW is in 2016, RsSHC014 and RsWIV16.
https://t.co/krO69CsJ94 is in 2013, RsWIV1. notice that this is before the beginning of the project
starting in 2016. Also remember that they told about only 3 isolates/live viruses. RsSHC014 is a live infectious clone that is just as alive as those other "Isolates".
P.D. somehow is able to use funds that he have yet recieved yet, and send results and sequences from late 2019 back in time into 2015,2013 and 2016!
https://t.co/4wC7k1Lh54 Ref 3: Why ALL your pangolin samples were PCR negative? to avoid deep sequencing and accidentally reveal Paguma Larvata and Oryctolagus Cuniculus?
Unfortunately the "This work includes the identification of viral sequences in bat samples, and has resulted in the isolation of three bat SARS-related coronaviruses that are now used as reagents to test therapeutics and vaccines." were BEFORE the
chimeric infectious clone grants were there.https://t.co/DAArwFkz6v is in 2017, Rs4231.
https://t.co/UgXygDjYbW is in 2016, RsSHC014 and RsWIV16.
https://t.co/krO69CsJ94 is in 2013, RsWIV1. notice that this is before the beginning of the project
starting in 2016. Also remember that they told about only 3 isolates/live viruses. RsSHC014 is a live infectious clone that is just as alive as those other "Isolates".
P.D. somehow is able to use funds that he have yet recieved yet, and send results and sequences from late 2019 back in time into 2015,2013 and 2016!
https://t.co/4wC7k1Lh54 Ref 3: Why ALL your pangolin samples were PCR negative? to avoid deep sequencing and accidentally reveal Paguma Larvata and Oryctolagus Cuniculus?
I'm agnostic on its various hypotheses about mechanisms of origin of furin-cleavage sites, but the part of this paper that suggests furin-cleavage site might be present in two of these SARSr-CoVs as a minor variant is embarrassingly bad science that shouldn't be amplified. (1/n)
Here is Table 1 of pre-print (https://t.co/7fQsreN77n) that shows data related to this claim. The mutations in question are present at 0.004% and 0.006%, corresponding to 6 or 7 Illumina reads out of >100,000 total. (2/n)
There are good deep-sequencing studies of CoVs, eg by @katrina_lythgoe (https://t.co/joX4kCqOEh), @LauringLab (https://t.co/TisAPvkCVp) & @KATarinambraun @tcfriedrich @trvrb @LouiseHMoncla (https://t.co/08EhfVAAL1). These studies find you can call variants to 2-3% frequency (3/n)
Table 1 of this pre-print is reporting "mutations" that introduce a furin-cleavage site at frequencies of 0.004% to 0.006%, which is orders of magnitude lower than what good studies have rigorously defined as a reasonable threshold (2-3%) to call mutations. (4/n)
As anybody who has ever analyzed viral or cancer deep sequencing knows, it's simply impossible to use standard Illumina sequencing to identify mutations at even 0.4% or 0.04%, let alone 0.004%. It's actually surprising when a given sequencing error isn't present at ~0.01%. (5/n)
Back to CoVs. In samples from two European bats, the authors found SARSr-CoVs that were just one mutation away from a functional FCS. But minor variants were sequenced from each that *had* a functional FCS already, just as is seen with some low path flu.
— Michael Worobey (@MichaelWorobey) December 16, 2021
11/
Here is Table 1 of pre-print (https://t.co/7fQsreN77n) that shows data related to this claim. The mutations in question are present at 0.004% and 0.006%, corresponding to 6 or 7 Illumina reads out of >100,000 total. (2/n)
There are good deep-sequencing studies of CoVs, eg by @katrina_lythgoe (https://t.co/joX4kCqOEh), @LauringLab (https://t.co/TisAPvkCVp) & @KATarinambraun @tcfriedrich @trvrb @LouiseHMoncla (https://t.co/08EhfVAAL1). These studies find you can call variants to 2-3% frequency (3/n)
Table 1 of this pre-print is reporting "mutations" that introduce a furin-cleavage site at frequencies of 0.004% to 0.006%, which is orders of magnitude lower than what good studies have rigorously defined as a reasonable threshold (2-3%) to call mutations. (4/n)
As anybody who has ever analyzed viral or cancer deep sequencing knows, it's simply impossible to use standard Illumina sequencing to identify mutations at even 0.4% or 0.04%, let alone 0.004%. It's actually surprising when a given sequencing error isn't present at ~0.01%. (5/n)
Meat is high in Glycosaminoglycans
(central to coronavirus's ability to attach to host cells)
Beef, pork poultry, seafood are rich in heparan sulfate (glycosaminoglycans), highly charged anchors for SARSCoV2
Meat surfaces critical factors for transmission
https://t.co/yP6lH22OTF
1/5 Science behind that tweet just in case anyone thinks I speak without awareness ;)
Glycosaminoglycans from fresh water fish processing discard - Isolation, structural characterization, and osteogenic activity
https://t.co/fyjac03IuV
SALMON MOUTHS
2/5 Salmon Mouths 2
Characterization of Glycosaminoglycans in Gaping and Intact Connective Tissues of Farmed Atlantic Salmon (Salmo salar) Fillets by Mass
3/5 Why does SARS-COV-2 like meat & seafood?
Glycosaminoglycan binding motif at S1/S2 proteolytic cleavage site on spike glycoprotein may facilitate novel coronavirus (SARS-CoV-2) host cell entry
https://t.co/DpHF1WmxeG
Glycosaminoglycans and
4/5 Glycosaminoglycans
Role of in Infectious Disease
(same authors as above)
https://t.co/3q5dn2Io3Q
Glycosaminoglycans in Infectious Disease
https://t.co/Dep7aJlpLP
Murine Coronavirus with an Extended Host Range Uses Heparan Sulfate as an Entry
(central to coronavirus's ability to attach to host cells)
Beef, pork poultry, seafood are rich in heparan sulfate (glycosaminoglycans), highly charged anchors for SARSCoV2
Meat surfaces critical factors for transmission
https://t.co/yP6lH22OTF
1/5 Science behind that tweet just in case anyone thinks I speak without awareness ;)
Glycosaminoglycans from fresh water fish processing discard - Isolation, structural characterization, and osteogenic activity
https://t.co/fyjac03IuV
SALMON MOUTHS
2/5 Salmon Mouths 2
Characterization of Glycosaminoglycans in Gaping and Intact Connective Tissues of Farmed Atlantic Salmon (Salmo salar) Fillets by Mass
3/5 Why does SARS-COV-2 like meat & seafood?
Glycosaminoglycan binding motif at S1/S2 proteolytic cleavage site on spike glycoprotein may facilitate novel coronavirus (SARS-CoV-2) host cell entry
https://t.co/DpHF1WmxeG
Glycosaminoglycans and
4/5 Glycosaminoglycans
Role of in Infectious Disease
(same authors as above)
https://t.co/3q5dn2Io3Q
Glycosaminoglycans in Infectious Disease
https://t.co/Dep7aJlpLP
Murine Coronavirus with an Extended Host Range Uses Heparan Sulfate as an Entry
1. Thread: RaTG13 Real or Fake?
A Norwegian Scientist @Vehuardo recently claimed RaTG13 is an "authentic virus"
https://t.co/tAXMNTwdhA
This failed to take into account the work of our DRASTIC colleagues & other published analyses.
This thread is a polite attempt to educate.
2. https://t.co/tw606vgHwp
which says RaTG13 doesn't make sense on how it was sequenced, or how the data got so messed up in the lab as to include copy paste mistakes, bat dna, pangolin dna, rice dna, mice dna, & nobody should use it to form conclusions until it's properly vetted
2 (cont)
"sequence is incomplete & provided segment doesn't function. The identified markers suggest partial match basis & actual virus itself as described by the sequence can't functionally exist due to incoherent structures that appear to be the result of sample contamination"
3. RaTG13 integrity is further attacked here:
The Validity of critical pieces of evidence for the natural origin of SARS-CoV-2 is Dubious, and needed to be
4. and here:
Major Concerns on the Identification of Bat Coronavirus Strain RaTG13 and Quality of Related Nature
A Norwegian Scientist @Vehuardo recently claimed RaTG13 is an "authentic virus"
https://t.co/tAXMNTwdhA
This failed to take into account the work of our DRASTIC colleagues & other published analyses.
This thread is a polite attempt to educate.
2. https://t.co/tw606vgHwp
which says RaTG13 doesn't make sense on how it was sequenced, or how the data got so messed up in the lab as to include copy paste mistakes, bat dna, pangolin dna, rice dna, mice dna, & nobody should use it to form conclusions until it's properly vetted
2 (cont)
"sequence is incomplete & provided segment doesn't function. The identified markers suggest partial match basis & actual virus itself as described by the sequence can't functionally exist due to incoherent structures that appear to be the result of sample contamination"
3. RaTG13 integrity is further attacked here:
The Validity of critical pieces of evidence for the natural origin of SARS-CoV-2 is Dubious, and needed to be
4. and here:
Major Concerns on the Identification of Bat Coronavirus Strain RaTG13 and Quality of Related Nature
#FauciEmails
Fauci told in February 2020 by woman that China underreported Wuhan Virus spread and death
She said her source is a Chinese exchange student (name redacted🧐 in the email), who was in contact with a nurse in Harbin, China.
https://t.co/c8o4snJ6pV via @MailOnline
Harbin is in the province of Heilongjiang, close to the border with Russia.
On Dec 10, 2019, the health commission of Heilongjiang confirmed that 13 students at the Harbin Veterinary Research Institute also had the infection.
https://t.co/zyYXK2Psv9
In 2018, China launched its first biosafety level-4 lab in Harbin.
The lab is being operated by the Harbin Veterinary Research Institute, under the Chinese Academy of Agriculture Science.
The lab's official address is in the Nangang district.
Then after looking at dozens of Harbin maps, finally this one lists another location of the Harbin Veterinary Research Institute.
It's in Harbin's Pingfang district.
Heilongjiang province, formerly known as Manchuria during WW2, Pingfang was where Japan's Unit 731 located
Harbin Veterinary Research Inst. was created in 1948, 3 years after Russia invaded Manchuria, then gave it to China.
In 1977, China covered up the spread of H1N1 which was leaked from a Chinese lab 😉, brought to an end any cooperation with Russia
https://t.co/zyYXK2Psv9
Fauci told in February 2020 by woman that China underreported Wuhan Virus spread and death
She said her source is a Chinese exchange student (name redacted🧐 in the email), who was in contact with a nurse in Harbin, China.
https://t.co/c8o4snJ6pV via @MailOnline
Harbin is in the province of Heilongjiang, close to the border with Russia.
On Dec 10, 2019, the health commission of Heilongjiang confirmed that 13 students at the Harbin Veterinary Research Institute also had the infection.
https://t.co/zyYXK2Psv9
In 2018, China launched its first biosafety level-4 lab in Harbin.
The lab is being operated by the Harbin Veterinary Research Institute, under the Chinese Academy of Agriculture Science.
The lab's official address is in the Nangang district.
Then after looking at dozens of Harbin maps, finally this one lists another location of the Harbin Veterinary Research Institute.
It's in Harbin's Pingfang district.
Heilongjiang province, formerly known as Manchuria during WW2, Pingfang was where Japan's Unit 731 located
Harbin Veterinary Research Inst. was created in 1948, 3 years after Russia invaded Manchuria, then gave it to China.
In 1977, China covered up the spread of H1N1 which was leaked from a Chinese lab 😉, brought to an end any cooperation with Russia
https://t.co/zyYXK2Psv9
Meet Yang Ruifu, CCP's biological weapons expert https://t.co/JjB9TLEO95 via @Gnews202064
Interesting expose of China's top bioweapons expert who oversaw fake pangolin research
Paper 1: https://t.co/TrXESKLYmJ
Paper 2:
https://t.co/9LSJTNCn3l
Pangolin
https://t.co/2FUAzWyOcv
Ruifu, obviously obsessed with PLAGUE,
https://t.co/7A9NiRlNoz
is a friend of Oliver Pybus (one of the Holmes, Andersen, Rambaut, Lipkin Gang)
Oliver Pybus helped Ruifu pump out CCP Propaganda
see next tweet
Pybus and Ruifu
An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
https://t.co/fl8yh0PSI8
and
China's control measures may have prevented 700,000 COVID-19
Email for academic queries:
[email protected] (H.T.);
[email protected] (C.D.); [email protected] (O.G.P.);
[email protected] (B.T.G.)
[email protected] (R.Y.)
Pangoscam
Interesting expose of China's top bioweapons expert who oversaw fake pangolin research
Paper 1: https://t.co/TrXESKLYmJ
Paper 2:
https://t.co/9LSJTNCn3l
Pangolin
https://t.co/2FUAzWyOcv
Ruifu, obviously obsessed with PLAGUE,
https://t.co/7A9NiRlNoz
is a friend of Oliver Pybus (one of the Holmes, Andersen, Rambaut, Lipkin Gang)
Oliver Pybus helped Ruifu pump out CCP Propaganda
see next tweet
Pybus and Ruifu
An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
https://t.co/fl8yh0PSI8
and
China's control measures may have prevented 700,000 COVID-19
Email for academic queries:
[email protected] (H.T.);
[email protected] (C.D.); [email protected] (O.G.P.);
[email protected] (B.T.G.)
[email protected] (R.Y.)
Pangoscam
1. WIV Research groups (archived pages) for Reference
dsRNA viruses molecular biology
https://t.co/lwrQoo6ygG
2. Emerging Viruses Group
https://t.co/ND56gVGOAn
3. Structural Biology of Viral Genome Replication
https://t.co/wUqc0YIP3X
4. Molecular Biology of hepatitis Viruses & Gene Therapy
https://t.co/snBbxkhNsC
5. Insect Virus Genetic Engineering Lab
https://t.co/S68mVOA2Ob
dsRNA viruses molecular biology
https://t.co/lwrQoo6ygG
2. Emerging Viruses Group
https://t.co/ND56gVGOAn
3. Structural Biology of Viral Genome Replication
https://t.co/wUqc0YIP3X
4. Molecular Biology of hepatitis Viruses & Gene Therapy
https://t.co/snBbxkhNsC
5. Insect Virus Genetic Engineering Lab
https://t.co/S68mVOA2Ob
November 3 - 9, 2019 -Wuhan Institute of Virology
International Training Course on Biosafety Laboratory Management and Technology
1. Daniel Feakes, head of UN Biological Weapons Convention implementation support agency
2. René Courcol, quality control system expert, France's BSL
List of Lecturers with short bios at
November 3 - 9, WIV Training Course: https://t.co/Bsd9yO40JP
YUAN Zhiming Professor, Wuhan Institute of Virology, CAS (Deputy Director)
SONG Donglin, Professor, Wuhan Institute of Virology, CAS ( Deputy Director of Wuhan BSL-4 Laboratory.)
Dr. TONG Xiao Senior Engineer at WIV (Molecular Virology & (HIV) infection, mechanical & vaccine immunology) On-site Manager & Chief engineer for WIV BSL-4 Lab construction, maintenance & biosafety equipment R&D.
Zhengli Shi, Director of WIV Center for Emerging Infectious Diseases, now in charge of scientific activity in BSL3 & BSL4. Viral pathogen discovery through sequencing techniques, wildlife-borne viral pathogens, particularly bat-borne viruses since 2004.
DENG Fei, Principle Investigator in Research Group on Viruses Resources & Biotechnology in WIV, also Director of Microorganisms & Viruses Resource Center.
Graduate of ECUST, went to Great Lakes Forestry Center, Canada in 2001 & Wageningen University, NL to study baculovirus.
International Training Course on Biosafety Laboratory Management and Technology
1. Daniel Feakes, head of UN Biological Weapons Convention implementation support agency
2. René Courcol, quality control system expert, France's BSL
List of Lecturers with short bios at
November 3 - 9, WIV Training Course: https://t.co/Bsd9yO40JP
YUAN Zhiming Professor, Wuhan Institute of Virology, CAS (Deputy Director)
SONG Donglin, Professor, Wuhan Institute of Virology, CAS ( Deputy Director of Wuhan BSL-4 Laboratory.)
Dr. TONG Xiao Senior Engineer at WIV (Molecular Virology & (HIV) infection, mechanical & vaccine immunology) On-site Manager & Chief engineer for WIV BSL-4 Lab construction, maintenance & biosafety equipment R&D.
Zhengli Shi, Director of WIV Center for Emerging Infectious Diseases, now in charge of scientific activity in BSL3 & BSL4. Viral pathogen discovery through sequencing techniques, wildlife-borne viral pathogens, particularly bat-borne viruses since 2004.
DENG Fei, Principle Investigator in Research Group on Viruses Resources & Biotechnology in WIV, also Director of Microorganisms & Viruses Resource Center.
Graduate of ECUST, went to Great Lakes Forestry Center, Canada in 2001 & Wageningen University, NL to study baculovirus.
1/4
Laulima Government Services (Fort Detrick BSL4) Contractor
(Alaka`ina Foundation) Hawaii DOD
Took over contract from Battelle
2/4
Tunnell Government Services
Jens Kuhn jumped ship from Battelle to steal
3/4 Jens Kuhn
https://t.co/rLxUmZoaQL
https://t.co/bOLwU9kTpW
https://t.co/WLi5NBTDEN
https://t.co/UF9gXup0El
https://t.co/5eVmln5sqN
wrote 6 tedious taxonomy papers with Fouchier
https://t.co/BAiXesvPxd
https://t.co/h4H4k7X4E3
Farzan & Kuhn ACE-2 &
4/4 Animal Origins of SARS Cov:
Insight from ACE2-S-Protein Interactions
https://t.co/sZp1fC4AdW
insights gained from study of SARS-CoV spike protein, which mediates viral entry & interaction with ACE2 receptor for SARS-CoV
Fang Li, Jens H. Kuhn, Michael Farzan
Kuhn's Appendix
https://t.co/QzTIyfdS0M
Global RNA Virome
https://t.co/zEdDcpoZKJ
S proteins of HCOVNL63 & SARS bind ACE 2 (with Farzan) https://t.co/K3RuTBo6R6!
Chapters 21, 22, 23 https://t.co/ckugrvRFwv
Chapter 57 in 1500 Page Book (Clinical Virology)
https://t.co/6ssn2LV0kS
Laulima Government Services (Fort Detrick BSL4) Contractor
(Alaka`ina Foundation) Hawaii DOD
Took over contract from Battelle
2/4
Tunnell Government Services
Jens Kuhn jumped ship from Battelle to steal
3/4 Jens Kuhn
https://t.co/rLxUmZoaQL
https://t.co/bOLwU9kTpW
https://t.co/WLi5NBTDEN
https://t.co/UF9gXup0El
https://t.co/5eVmln5sqN
wrote 6 tedious taxonomy papers with Fouchier
https://t.co/BAiXesvPxd
https://t.co/h4H4k7X4E3
Farzan & Kuhn ACE-2 &
4/4 Animal Origins of SARS Cov:
Insight from ACE2-S-Protein Interactions
https://t.co/sZp1fC4AdW
insights gained from study of SARS-CoV spike protein, which mediates viral entry & interaction with ACE2 receptor for SARS-CoV
Fang Li, Jens H. Kuhn, Michael Farzan
Kuhn's Appendix
https://t.co/QzTIyfdS0M
Global RNA Virome
https://t.co/zEdDcpoZKJ
S proteins of HCOVNL63 & SARS bind ACE 2 (with Farzan) https://t.co/K3RuTBo6R6!
Chapters 21, 22, 23 https://t.co/ckugrvRFwv
Chapter 57 in 1500 Page Book (Clinical Virology)
https://t.co/6ssn2LV0kS
1. Some useful, albeit not fully developed, critiques of:
“The Origins of SARS-CoV-2: A Critical Review"
https://t.co/C9TyRyqHUr
have just been published here:
https://t.co/qCmzGCzRxn
by members of DRASTIC & others
@angoffinet @BahulikarRahul @MonaRahalkar @gdemaneuf
2. A refreshing contrast to the so-called "expert reactions" found here, including from one of the authors of the review (Prof David Robertson)!
"expert reaction to a preprint reviewing the evidence on the origins of SARS-CoV-2"
https://t.co/6kG6rstweP
3. Peter Gutierrez points out in his response that 4 of the authors of “The Origins of SARS-CoV-2: A Critical Review”, also wrote “Proximal Origin of SARS-COV-2”.
His critique focuses on:
1. RaTG13
2. Enhanced adaptation to the human host
https://t.co/eW8b2iK5xe
4. As to be expected, Sydney University and its iconic virologist, Eddie Holmes, who is "not available for interview", are crowing over this biased review
https://t.co/xrjpN1NxpO
This review contains elementary errors as exposed here:
1. https://t.co/YJ50huifly
one of the authors (Stuart Neil) then claimed
"Didn’t N501Y come up in ACE2 TG mice too?
https://t.co/HscNSEKdrZ
“The Origins of SARS-CoV-2: A Critical Review"
https://t.co/C9TyRyqHUr
have just been published here:
https://t.co/qCmzGCzRxn
by members of DRASTIC & others
@angoffinet @BahulikarRahul @MonaRahalkar @gdemaneuf
2. A refreshing contrast to the so-called "expert reactions" found here, including from one of the authors of the review (Prof David Robertson)!
"expert reaction to a preprint reviewing the evidence on the origins of SARS-CoV-2"
https://t.co/6kG6rstweP
3. Peter Gutierrez points out in his response that 4 of the authors of “The Origins of SARS-CoV-2: A Critical Review”, also wrote “Proximal Origin of SARS-COV-2”.
His critique focuses on:
1. RaTG13
2. Enhanced adaptation to the human host
https://t.co/eW8b2iK5xe
4. As to be expected, Sydney University and its iconic virologist, Eddie Holmes, who is "not available for interview", are crowing over this biased review
https://t.co/xrjpN1NxpO
This review contains elementary errors as exposed here:
1. https://t.co/YJ50huifly
one of the authors (Stuart Neil) then claimed
"Didn’t N501Y come up in ACE2 TG mice too?
https://t.co/HscNSEKdrZ
All your natural origin friends in one place ;)
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) July 7, 2021
Origins of SARS-CoV-2: A Critical Reviewhttps://t.co/j4A4rtmi8S
via @Topo_Ligio
Fallacy of the "straw mouse", denying evolution in wild type mice, when the claim is actually that it may have "evolved" in hACE2 mice, NOT wild mice. pic.twitter.com/7LCnSAhw6g
1. Reading between the Lines - interview from Sept 2017
From wildlife to humans with the PREDICT project
– an interview with Tracey
2. First of all we need to take into account the EcoHealth/PREDICT - Lipkin connection
https://t.co/kKtDTYQD9D
Read it carefully...
Ecohealth/DARPA and PREDICT UC Davis smuggled viruses back to the US for GOF work by Lipkin and Atlanta CDC BSL4 (Dr. Stuart Nichol) and USAMRIID
3. In the interview, Tracy Goldstein does not specifically clarify or state this fact, we need to read between the lines/
"examine the sequences of the coronavirus spike protein"
"examine" refers to US Lab work by Lipkin and others
4. They were sequencing as many coronaviruses as they could and experimenting on them at US Labs, seeing if they could become more pathogenic or cross the species barrier
5. Goldstein says:
"to further "understand & characterise" "prioritised viruses" to see if they can jump to humans.
Only one way to do that, isn't there?
Shipping back the deadliest viruses to the US via US consulates as exposed via leaks from Georgia
https://t.co/va6Be7w2HL
From wildlife to humans with the PREDICT project
– an interview with Tracey
2. First of all we need to take into account the EcoHealth/PREDICT - Lipkin connection
https://t.co/kKtDTYQD9D
Read it carefully...
Ecohealth/DARPA and PREDICT UC Davis smuggled viruses back to the US for GOF work by Lipkin and Atlanta CDC BSL4 (Dr. Stuart Nichol) and USAMRIID
Yes, he was included above in the last tweet.
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) September 26, 2020
Lipkin is a key player in this sordid saga, who received viruses via Predict/Prophecy/Ecohealth/Darpa for experiments in the mailman lab (according to our "friend" Quammen in his book Spillover) found by @gdemaneuf pic.twitter.com/1fq20TSR3A
3. In the interview, Tracy Goldstein does not specifically clarify or state this fact, we need to read between the lines/
"examine the sequences of the coronavirus spike protein"
"examine" refers to US Lab work by Lipkin and others
4. They were sequencing as many coronaviruses as they could and experimenting on them at US Labs, seeing if they could become more pathogenic or cross the species barrier
5. Goldstein says:
"to further "understand & characterise" "prioritised viruses" to see if they can jump to humans.
Only one way to do that, isn't there?
Shipping back the deadliest viruses to the US via US consulates as exposed via leaks from Georgia
https://t.co/va6Be7w2HL
Considering international transport of pathogens under PREDICT & DTRA rules, SCH014 & possibly other viruses from Yunnan must have been sent via a US Consulate, either Wuhan or Chengdu as hand-carry items to Dr. Stuart Nichol at Atlanta CDC exactly as was done in Georgia in 2012! pic.twitter.com/owU8BMZnaD
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) September 4, 2020