Evidence of Genetic Engineering in SARS-COV-2

Part 4 A Sting in the Tale of Kristian Andersen

When @K_G_Andersen "opened up" about the infamous email in which he stated "Eddie, Bob, Mike, and myself all find the [SARS-CoV2] genome inconsistent with expectations from evolutionary theory" he never quite told us exactly what he saw, but still he left a few clues.
In a response to questions from @nicholsonbaker8 he mentioned the FCS and the RBD, but also "a unique restriction enzyme site (BamHI) ...a higher level of conservation towards the end of the spike...other residues that had been observed to be important from research with SARS"
Since much of the focus to date has been on the FCS and RBD, let's instead take a look at a different region towards the end of the spike that had been of interest to SARS researchers - a "Cysteine-rich endo-domain" - Cysteine denoted by C:
In 2007, SARS researchers had tried exchanging some of these Cysteine (C) residues for Alanine (A) in parts of this region and discovered that cell fusion (merging and entry into the cell) was reduced by 50-60% when they did so.

https://t.co/iUEMYnldU3
The second half of the spike (S2) is far more conserved between coronaviruses than S1. On an amino acid basis there may be only a handful of mutations in several hundred bases. Looking at just the last 40, there's remarkable homology over time, species and geographic region.
One mutation stands out between SARS-COV-2 and others known previously. A single Ala is present in most viruses except SARS-COV-2 where it has been replaced by Cys.

Could this be a sign of engineering? If Cys->Ala reduces cell fusion, Ala->Cys might be expected to enhance it.
Astonishingly, on a nucleotide basis all 3 codons have mutated between SARS and SARS-COV-2. GCA has become TGT. This is extremely improbable under natural evolution. Occasional single nt mutations are expected, but here are three in one base-in a region that is highly conserved.
For Ala to mutate to Cys via point mutations it must first mutate to intermediate residues in steps. We might expect to find some of these in nature. Some codon combinations near C are stop codons, dead ends.

The path from Ala to Cys seems "inconsistent with natural evolution".
But are there any other coronaviruses with Cysteine in this position? Prior to SARS-COV-2 there were only two - ZC45 and ZC21, viruses sequenced by PLA researchers. These were identified (for different reasons) as the potential backbone for an engineered virus by @drlimengyan1.
Since the outbreak, new coronavirus discoveries have been springing up like weeds with features unseen prior to SARS-COV-2. Recently there's been a concerted effort to spam Genbank with fakes and frauds

Please check date added/modified if you find a CoV with similar mutations.
Link to earlier parts:

https://t.co/CeztISvFQN

More from All

You May Also Like

#Bookmark this

The full story of || Dhruv ||

We’ll see How Dhruv occupied a fixed position in the northern sky?

I repeat “Untold Unsung now Unearthed”

Go through entire thread carefully.

OM NAMO BHAGWATE VAASUDEVAAY

RT & spread the knowledge.
Any questions use #AskPratz


.... continuing from previous thread/story

O prince! Thus concentrate on that omnipotent eternal Lord with the mantra - ‘OM NAMO BHAGWATE VAASUDEVAAY’ .

https://t.co/H62ehDT3ix


The prince Dhruv greeted the sages and continued on his journey. At last, he reached a beautiful forest Madhuvan on the bank of the river Yamuna. It was the same forest, which was later occupied by a demon Madhu.


Shatrughana, the youngest brother of Sri Rama had killed demon Lavan, son of Madhu in the same forest & founded the township of Mathura. In the same forest, prince Dhruv decided to carry out his penance. As per the dictate of the sages, he began to recite the mantra continuously


Very soon, the earth began to move because of Dhruv’s severe penance. Even the seat of Indra could not remain stable. A stampede resulted among the gods. The gods then hatched a conspiracy to disturb the penance.
Trump is gonna let the Mueller investigation end all on it's own. It's obvious. All the hysteria of the past 2 weeks about his supposed impending firing of Mueller was a distraction. He was never going to fire Mueller and he's not going to


Mueller's officially end his investigation all on his own and he's gonna say he found no evidence of Trump campaign/Russian collusion during the 2016 election.

Democrats & DNC Media are going to LITERALLY have nothing coherent to say in response to that.

Mueller's team was 100% partisan.

That's why it's brilliant. NOBODY will be able to claim this team of partisan Democrats didn't go the EXTRA 20 MILES looking for ANY evidence they could find of Trump campaign/Russian collusion during the 2016 election

They looked high.

They looked low.

They looked underneath every rock, behind every tree, into every bush.

And they found...NOTHING.

Those saying Mueller will file obstruction charges against Trump: laughable.

What documents did Trump tell the Mueller team it couldn't have? What witnesses were withheld and never interviewed?

THERE WEREN'T ANY.

Mueller got full 100% cooperation as the record will show.