⏩ Alt Goes Mainstream ⏪
How did we get here? Who are the players? Where do we go next?
Thread 🧵below 👇
And check out Substack for how the confluence of a number of trends will change investing as we know
2/ FinTech has ushered in new waves of access to different types of alternative investments.
Over the past decade, we witnessed a groundbreaking era of democratized access to alternative investments.
Not long ago, it seemed unthinkable that individual investors could ...
3/ 💳 invest in fractions of a loan. @LendingClub
made that possible.
💸 invest $20 alongside Sand Hill Rd VCs into a fast-growing startup. @joinrepublic made that possible.
🏦 invest alongside endowments into a top private equity fund. @icapitalnetwork made that possible.
4/ We have now hit the era of alt alt assets.
People can now invest in everything from classic 🚗 to 🎨 to 🏀 & 🏈 cards thanks to democratized access to investing in real things.
5/ The hype is real.
If there's any cohort of people who view culture as a financial asset, it's Millennials and Gen
Follow the live tweets @LeedsClimateCom #LeedsClimate #PCANcities
We're looking forward to hearing responses to the roadmap's presentation by members of the Leeds Citizens' Jury, Polly Cook of Leeds City Council, @SimonBowens of Friends of the Earth and Elizabeth Edgington of @BITC
Leeds’ carbon footprint has gone down: between 2000-2019 emissions fell by 40% (largely due to national decarbonisation of the grid).
Our share of the global carbon budget in 2020 is 31m tonnes; at ca. 4m tonnes a year, that’s used up by 2029
During lockdown #1, emissions were ca. 43% lower – overall, in 2020, they were ca 13% lower than normal. Sounds encouraging, but this only delays the point we eat up our carbon budget by 2 months!
Following science-based targets, Leeds needs to make 70% reductions by 2025 – which means another 25% reduction in emissions in the next 4-5 years.
We need to accelerate significantly!
1. High-tech Toilets
Japanese toilets will not only wash and warm your bum, will also play music for you so no one can hear your business
2. Wrinkle Remover
Someone must have really hated ironing. They have a hands- and effort-free shirt wrinkle remover that eliminates wrinkles
3. Butter Applicator
Someone created a portable butter stick, just because they can
4. Braille Cans
Drink cans have information in braille on top to help those with sight issues.
5. Feeding Falsies
They’ve invented a device that allows fathers to approximate the benefits of breastfeeding.
I'll share some findings in this thread.
CCing @CO2Guerrillas here, in case they would like to share.
A very quick intro:
This device measures:
I spent ~$200 on Amazon. It pairs with your phone and you can watch data come in every minute or so.
A lot of covid transmission is airborne. So, having clean air is a must for reducing transmission.
A great way to see how much clean air you are getting is to measure CO2 concentration.
Too high -> you could use more ventilation -> open some windows!
So, I walked around town and took some measurements.
Outdoor CO2 concentration should be about 400 ppm. I haven't calibrated my device yet, so I measured ~470. Close enough.
<800 is good for indoors. Something like 2000 is very bad.
For a reference: inside my apartment I quickly get ~1000 ppm if I don't have windows open. Maybe ~1500 if things get bad.
If I crack some windows, even just barely, it gets down to ~600 ppm very quickly, and my heater can keep the apartment ~70 F no problem.
Validate HTML? Yep. We haven’t really cared about ‘valid HTML’ for valid HTML’s sake for about a decade, but certain errors can actually be pretty significant. What’s wrong with this picture?
It’s this lil’ fella right here. isn’t allowed in the , so when the browser encounters the , it assumes the should have been closed already.
This is a feature. This is what allows us to omit certain closing tags like , , , and—you guessed it!—. The appearance of certain opening tags implies the closing of certain preceding ones.
The practical upshot of which is that non- elements early-terminate the tags, pushing all of your important resources into the . Oops!
That said, there are caution flags I'd like to raise:
1) It's brutally hard. I outline the steps here https://t.co/MZ0beEl0UU
2) Selecting well, and far beyond financials factors, is a skill that takes reps to become proficient. What I thought were slam dunks 10 years ago scare me today.
Please don’t get jacked up on cheap SBA money and go tag the 14th thing you look at.
3) The required personal guarantee is no joke. Yes, it’s 10 year money. Yes, you’re going to buy it at a high cf yield. But, SMBs are volatile and often for reasons that aren’t initially obvious.
If things turn against you, you’ll declare bankruptcy. Seen it happen. Not pretty.
4) You’re almost always buying a risky job.
The idea of cashing checks and “allocating capital” is a joke. Someone somewhere has done it, but I’ve never seen it.
It’s going to be a challenging 7/365 grind to hopefully make very good money. That’s the best you can hope for.
5) Speaking of risk, as the owner, you’re the last to eat. Stuff happens and reserves need to be built to survive long-term. Working capital grows. Equipment breaks.
You’ll often have top employees getting more cash out of the business than the owner.
Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro
We generate single-cell and spatial reference maps of the human uterus and dissect the signalling pathways that determine cell fate of the epithelial lineages in the lumenal and glandular microenvironments.
To study cell-signalling we use Cell2location (@vitaliikl) and develop CellPhoneDBv3 that considers cellular coordinates for the inference of cell-cell communication
We mapped 3D endometrial organoid cultures and benchmark the model to our uterine atlas. To do so, we develop a novel computational pipeline to align in vitro and in vivo datasets.
Our comparison highlights common pathways regulating the differentiation of secretory and ciliated lineage in vivo and in vitro.
First off: hello! @marazepeda here. I used to be an economic reporter for places like @planetmoney & @Marketplace. (If credentials are your kink I even graduated at the top of my class from @columbiajourn 🎉) Follow along, friends, as we attempt to unravel this rat's nest.
We get this message: "Uh, WTF there is an article about Zebras without mentioning Zebras." This happens more often than you might think. (What's the best is when men tweak your ideas and then put another name on it like camel and publish in @HarvardBiz)
As a refresher @operaqueenie @JenniferBrandel @operaqueenie + @marazepeda coined the term in this essay written in, ahem, 2017 https://t.co/ipWzgPxfg1 You can see why the @TechCrunch article by @beckshoneyman sounded...familiar but what was really weird is
The examples @beckshoneyman cited of so called Zebra companies? @joinHandshake and @turo? Uh no. Handshake has raised $150M and Turo has raised $450M. These are squarely in the #VC funded 🦄 camp. AS THEY SHOULD BE! No shade to VC! You do you! However...
On web-archive: https://t.co/RGxGjJm5Jc or direct: bit. ly/2LRL8Wt [no spaces course]
The initial GMO4D is on webarchive too: https://t.co/CFAhGWPahB !
Also direct: bit. ly/35RyHAE [no spaces]
Pfizer has been fined over $4.7 billion since 2000 for false claims acts, off-label or unapproved promotion, Foreign corrupt practices, with over $103M for "drug or medical equip safety violations" & over $34M for "kickbacks & bribery."
They focused on the wrong protein for GO-vaccine, new Cambridge study https://t.co/7Q2emCCNgp. ADE/PP reaction prevalent by the spike-protein....
Under no legal definition those therapies can be called "vaccine"! Inducing by GMO a foreign substance in the body is certain. Immunity is questionable. So is transmitting!
Among "side-effects" of course myelitis, autoimmune disease, vaccine enhanced disease, are mentioned by FDA.
In other words the presumed EXTINCTION mean> ADE/PP.
(includes free resources and everything else you need to get started)
Before we begin, I want to congratulate you on your decision to learn how to code using Python.
I still remember how I wrote my first piece of code 6 years and all the amazing and cool things I've been able to do with it ever since.
(2 / 24)
Make sure to keep in mind that it is probably best for you to keep your expectations in check.
Don't expect to make AAA games or state of the art machine learning models in a week.
(3 / 24)
Programming is not something that you can learn in a single week, it takes consistent effort and dedication over time to get good at it.
With all that being said, let's dive straight in.
(4 / 24)
In order to write Python code, you'll need to install Python on your system.
Linux and macOS users can skip this step because they come pre-installed with Python.
Download link: https://t.co/KSZ4Qd6CNk
(5 / 24)
The launch of so many satellites might change the appearance of the night sky for ever and the trails they leave in astronomers' cameras and the potential for interference with radio telescopes are serious problems 2/n
Those problems are particularly acute for those searching for near-Earth or threatening asteroids, for example, though any large survey of the sky is affected. 3/n
It was good to see @spacex, Amazon's Kuiper project and @oneweb present, and to hear that the latter have dropped their plans from more than 40,000 satellites to 'only' 6372. All the speakers were positive about working together. 4/n
@OneWeb And a lot has been done. All three companies talked about making sure their satellites were fainter than 7th magnitude soon after launch, which would make them invisible to the naked eye and avoid the worst problems for large surveys 5/n
It's a lot on Channels (the new video function in WeChat).
Here are my notes & comments in parentheses:
WeChat daily usage looks like this:
1.09 Bn users log in, 330mm use video chat
780mm users view Moments feed (like FB feed), 120mm users post to Moments
360mm read articles, 400mm use mini programs
Why're we going after video?
In last 5 years, users are sending 33x more video msgs in chat, 10x more videos into their Moments feed.
Not everyone can write long content, but doing video requires new acct system (current public acct system is subscription based), we tried in 2017
but didn't get too far. But since video SO obviously the big thing in next 10 yrs, we began working on it for real in 2019. (Very late, if you ask me).
Channels is NOT like your WeChat ID, which is for PRIVATE comms. It's WeChat's foray into public content.
So now, you need a new Channel ID to make content, but not view content (use your existing WeChat ID & leverage social network / relationships).
WeChat tried 3 separate internal algo teams. Found that algo rec was much worse than people rec content performance.
Worth its long length, although the conclusion is muted, for acceptability I imagine.
@Rossana38510044 @ydeigin @MonaRahalkar @BahulikarRahul Original x Rewritten
@Rossana38510044 @ydeigin @MonaRahalkar @BahulikarRahul @nicholsonbaker8
Some takes out of this master piece. Head been spinning for some time.
@Rossana38510044 @ydeigin @MonaRahalkar @BahulikarRahul @nicholsonbaker8 1- It was Fauxi & his moneytrail from the beginning:
@Rossana38510044 @ydeigin @MonaRahalkar @BahulikarRahul @nicholsonbaker8 The Wuhan Lab&Leak "coincidence" argument leads to the other Lab&Leak "coincidence" argument:
Q: How will I know if I am getting paid?
A: You will get a message from Team Snapchat that looks like the below message 2-3 weeks after the snap has gone live. At this point it important that you verify your email address.
Q: How long after I’ve been notified I qualify, will I know for how much?
A: my experience is that usually 7-10 days after you get the qualifying message, you get a message with the amount, it will look like this. This message will include a unique access code for HyperWallet.
Q: How do I set up my HyperWallet?
A: Around three weeks after you get the payment amount you will get an email to your verified email from Snapchat Pay. It will look like this and will require you to fill out some tax forms, takes like 10 min.
Q: How long does it take to actually get the money in my account?
A: it took me like 7 days from when I had my HyperWallet approved before I got the money into my HyperWallet account. I recommend you set up auto withdraw. You can send money to PayPal, Venmo or bank account.
What a lot of people don't know, is how to effectively search for the right answer.
Let me help you improve your Google search skills with these 16 tips!
1. NOT Logical operator:
You use this operator to exclude results if it contains the operand using "-" e.g.
2. OR Logical operator:
This is a binary operator that returns a result if it contains both operands or one of them e.g.
3. AND Logical operator:
This is a binary operator that returns a result containing it's operant on the left and right hand-side e.g.
html AND css
This returns a result if both terms are in the search result.
4. Exact match:
Use quotation marks to return an exact match in your search result e.g.
python tutorial "full course"
It's not too late....
The Cabal has many layers & secretly controls everything on our planet. But, so many on this planet are completely clueless to who they truly are. Humanity is rapidly running out of time to prepare for coming events. The Cabal is a very carefully structured organization,
a hierarchy of non-physical dark matter that feeds off negative energy. This energy has no need for material possessions; only more negative energy which is its life force.
This energy has consciousness just like non-physical light matter or positive energy which humans
mistakenly refer to as God. Benevolent Galactic beings will teach us in the not too distant future that they consider the God construct mere dogma, superstition for the purpose of control. Love is of the highest frequency, the highest frequency of light which humans interpret as
humans interpret as love & bliss. God is light, extremely high cosmic energy. We are in the process of returning to balance, there must be balance always. We are experiencing this incredible turbulence & chaos on this planet currently because everything is out of balance &
If you're not familiar with Clojure, here is how the code looks like. Clojure is a Lisp-derivative which is different than most Fortran/C-derivative languages that we use today.
At first, the syntax was very off-putting (my god these parentheses!!), but then you start appreciating the elegance of the language and after sometime you stop being bothered by the syntax.
One of the things that Clojurists (I guess that's what they call themselves 😅) always talk about is how they think of everything as data even the language's syntax! Every Clojure expression is just a plain ol' Clojure list that the complier reads and executes.
And for that reason macros in Clojure are first class citizens (in fact a lot of Clojure built-in functionality is built with macros). Macros are functions that take your code as input (remember your code is just a list data structure) and it transforms your code into...
I'll provide a response to @nilbold's concerns in hopes of a fruitful exchange of information.
the issue of bestiality is one of consent and an uneven power dynamic that leads to abuse— nude antifa kobold (@nilbold) January 8, 2021
a horse dick dildo doesn't make someone a zoophile
yes this is the 500th time this discourse has surfaced since 1998
furries please, i'm begging you, there's more important things afoot
RAINN has a rather serviceable model for sexual consent for humans: https://t.co/0gelDI53Fa
And Planned Parenthood has a more comprehensive one: https://t.co/8QQ1GsyGGT https://t.co/PQKkYcpftl
What's interesting is that both models fit and can be successfully applied to...
nonhuman animals regardless of if their prospective partners are of the same species or not. https://t.co/wrE2jLPWHp
Now we need to explore power imbalance in human sexual relationships to understand what degrees of power imbalance are tolerated or not, and why.
We must also note that "Power Imbalance" does not inherently mean bad things. There are Negative or Harmful Power Imbalances (like when the powerful have complete control over vital resources and the powerless are aware of this) and there are Positive or Growth Power Imbalances
(Like when one is an expert martial artist and teaches their SO how to defend themselves).
Power exists in all relationships. Having power means to have a sense of control, to have choices and the ability to influence our environment and others.
I've been finding myself coming back to this framework often when talking to founders about growth.
1/ As a startup, it's essential that you, and your team, have a clear understanding of how your business is likely to grow. We call this building a Growth Model. With this, you'll know which growth investments to make right away, which to avoid, and which to double-down on.
2/ Our advice is to think about your business like a high-performance race car. The same four components that help a car drive faster also help your business grow:
1. ⚙️ The (Growth) Engine: Self-sustaining growth loops that drive most of your growth (e.g. virality, perf marketing, content, sales)
2. 💥 Turbo boosts: One-off events that accelerate growth temporarily but don’t last (e.g. PR, events, Super Bowl ads)
3. 💧 Lubricants: Optimizations that make the growth engine run more efficiently (e.g. improved conversion, a stronger brand, higher customer retention).
4. ⛽ Fuel: The input that your engine requires to run (e.g. capital, content, users).