How to run a company (in priority order):

1: Define a crystal clear north star

Great companies know their destination.

Everyone rowing in one direction.

The best north star? A SIMPLE, measurable metric.

Get it right, and watch the magic unfold! 💫
2: Hire uncomfortably good people

Ah, my favorite line!

Hire people you have no right to hire.

Who are so good it makes you nervous.

Who force everyone to step up their game.

Always level up 🦾
3: Create a culture of urgency

Nothing is more powerful than a group of people making every day count 🔥⚡️🚨
4: Make sure no one gets blocked

You’re paying good people good money.

Make sure they don’t get stuck!

Demotivating for them 🤦

Disastrous for the bottom line.
5: Occasionally take big swings

And when you do, go ALL IN!

There’s one thing you can always count on:

The world is changing.

There’s no better way to future-proof your business then disrupting yourself.
6: Nail the attitude

Enthusiasm, hard work, care for each other.

These are winning traits 🏆

Culture establishes the traits that define how your people operate.

A relentless optimism overcomes all obstacles.
Now imagine a company with:
1/ A clear north star
2/ Exceptional people
3/ Urgency at every corner
4/ Empowered teammates
5/ Fearless risk taking
6/ And a great attitude

… that’s a WINNER!
Ok that’s it folks!

How to run a company in 6 steps.

Follow me for more hands-on business threads 📈

Now go crush it!

More from Ryan Breslow 🕺

Over the last 7 years I’ve built 2 multi-billion dollar companies.

It’s been grueling. We don’t share these lessons enough.

So I decided to do that over the last month.

The feedback has been awesome - 25k new followers in 1 month.

Here’s a roundup of all of the threads 👇

Why Bolt is the first tech unicorn to shift to a 4 day work


I’ve built both a $4B company and a $1B company over the last 7 years.

Here are the 12 mindset rules that got me


We 10X’d our company in the last 10 months.

Here are the 10 tactics to making every day


We’ve closed more deals in the last 90 days than in all of Bolt history.

Here are 10 tips on how to negotiate your best

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Viruses and other pathogens are often studied as stand-alone entities, despite that, in nature, they mostly live in multispecies associations called biofilms—both externally and within the host.

https://t.co/FBfXhUrH5d


Microorganisms in biofilms are enclosed by an extracellular matrix that confers protection and improves survival. Previous studies have shown that viruses can secondarily colonize preexisting biofilms, and viral biofilms have also been described.


...we raise the perspective that CoVs can persistently infect bats due to their association with biofilm structures. This phenomenon potentially provides an optimal environment for nonpathogenic & well-adapted viruses to interact with the host, as well as for viral recombination.


Biofilms can also enhance virion viability in extracellular environments, such as on fomites and in aquatic sediments, allowing viral persistence and dissemination.