Fun fact: the standard advice for if a dog, cat, or human bites your hand, is to feed the bite. Push your hand further into their mouth, forcing the jaw open.
Nurses, EMTs, veterinarians, etc are taught to respond this
This vicious wolf attack illustrates proper technique.
They have to be evaluated while keeping the fist closed.
This, if the bite punctured the MCP joints or tendon sheath, makes infection much more likely.
Young, drunk men, while partying. And they get bitten mostly on the face.
https://t.co/XlUlMlDeiH
Incisor: 43.3kg
First Molar: 120.66kg https://t.co/EfRbZEZjsh
All subjects ceased applying pressure citing tooth pain, well before maximal pressure was exerted. https://t.co/IRGjQxoTi5
He also used a phagodynamometer to test crush pressures of various foods, with surprising results. He found that bread crusts can be incompressible enough to shatter tooth cusps.
For two seconds. https://t.co/Vk2TqyKUxc
More from Anosognosiogenesis
Look at some historical examples of mass psychogenic illnesses: dancing plagues, laughing plagues, meowing nuns,
Here's a video on them:
They are interesting, but what is more interesting to me is Culture Bound Syndrome. https://t.co/hMKaApUMZn
Basically: mass psychogenic illness, and presentation of various mental illnesses, do not occur in a vacuum. Cultures shape them.
For instance, Koro.
There have been several mass outbreaks of men completely convinced their penises are shrinking, anchoring them with string at night so they don't get sucked back inside.
Almost all in Southeast
Here's a description of one outbreak in Hainan in 1984:
Here's a video on them:
They are interesting, but what is more interesting to me is Culture Bound Syndrome. https://t.co/hMKaApUMZn
Basically: mass psychogenic illness, and presentation of various mental illnesses, do not occur in a vacuum. Cultures shape them.
For instance, Koro.
There have been several mass outbreaks of men completely convinced their penises are shrinking, anchoring them with string at night so they don't get sucked back inside.
Almost all in Southeast
Here's a description of one outbreak in Hainan in 1984:
So you want to generate interesting melodies.
1. Make a file called 1235.txt containing, one per line, all 24 unique permutations of the elements 1 2 3 5.
2. Cp 1235.txt to D.txt
3. Use sed to convert the numbers in D.txt to notes. Now you have 24 permutations of the major tetrachord in D.
4. Play them each. If it sounds like it increases tension, mark the beginning of that cell in 1235.txt with a +. If it sounds like it decreases tension, mark with a -.
Now those 24 melodic cells are divided into two groups: tension increasers and resolvers.
5. Rinse and repeat for all 12 keys.
You now have 13 plaintext files, filled with stuff like + 1 2 5 3 and - D E F# A
6. Figuratively roll dice to decide, given a +/- cell, what the next cell should be.
33% chance a + follows a +, etc.
Now you're outputting a stream of dynamic tensions: ++-+++-+-+---+ etc
1. Make a file called 1235.txt containing, one per line, all 24 unique permutations of the elements 1 2 3 5.
Claude Shannon made this machine to play the hex board game.
— Anosognosiogenesis (@pookleblinky) January 21, 2021
It is literally just a mesh of resistors and some light bulbs. No logic gates, no programming, nothing at all resembling AI.
Check it out: https://t.co/Zoyc9TmBcN pic.twitter.com/EANeMosPhT
2. Cp 1235.txt to D.txt
3. Use sed to convert the numbers in D.txt to notes. Now you have 24 permutations of the major tetrachord in D.
4. Play them each. If it sounds like it increases tension, mark the beginning of that cell in 1235.txt with a +. If it sounds like it decreases tension, mark with a -.
Now those 24 melodic cells are divided into two groups: tension increasers and resolvers.
5. Rinse and repeat for all 12 keys.
You now have 13 plaintext files, filled with stuff like + 1 2 5 3 and - D E F# A
6. Figuratively roll dice to decide, given a +/- cell, what the next cell should be.
33% chance a + follows a +, etc.
Now you're outputting a stream of dynamic tensions: ++-+++-+-+---+ etc
An interesting thing about carp is that they can go into anoxic hibernation and switch to an anaerobic metabolism based on converting glycogen to ethanol.
The waste ethanol is diffused out the gills
https://t.co/V3D1umHf04
Carp can switch over to an anaerobic metabolism and quietly exhale booze until the situation gets better.
They basically evolved the same metabolic pathway as yeast, independently.
In theory, if you spent a few thousand years breeding carp for it, you could use them to make booze.
They'd be enormous, almost entirely glycogen deposits with a fish added as an afterthought.
The really interesting thing about anaerobic carp, is that they can go 4-5 months without oxygen by relying on liver glycogen.
You, a human, have only about 100 grams of glycogen in your liver, about 400 more grams in your skeletal muscles. Call it 500 grams total.
In humans, glycogen is also burned for energy. This is where the marathon runner's bonk comes from: you only have about 2,000 calories worth, and running a marathon burns those 2,000 calories.
The waste ethanol is diffused out the gills
https://t.co/V3D1umHf04
Carp can switch over to an anaerobic metabolism and quietly exhale booze until the situation gets better.
They basically evolved the same metabolic pathway as yeast, independently.
In theory, if you spent a few thousand years breeding carp for it, you could use them to make booze.
They'd be enormous, almost entirely glycogen deposits with a fish added as an afterthought.
The really interesting thing about anaerobic carp, is that they can go 4-5 months without oxygen by relying on liver glycogen.
You, a human, have only about 100 grams of glycogen in your liver, about 400 more grams in your skeletal muscles. Call it 500 grams total.
In humans, glycogen is also burned for energy. This is where the marathon runner's bonk comes from: you only have about 2,000 calories worth, and running a marathon burns those 2,000 calories.
More from Health
Before we get too far into 2021, I thought I’d write a thread recapping some of the research that came out of my lab in 2020. Most of this work was led by my talented team of graduate students, Kerrianne Morrison, @kmdebrabander, and @DesiRJones.
Back in January, a news story was published about Kerrianne’s study showing improved social interaction outcomes for autistic adults when paired with another autistic partner.
A detailed thread about the study and a link to the paper can be found here (feel free to DM me your email address if you’d like a copy of the full paper for this study or any of our studies):
Another paper published early in 2020 (it appeared a few months earlier online) showed that traditional standalone tasks of social cognition are less predictive of functional and social skills among autistic adults than commonly assumed in autism research.
Next, @kmdebrabander led and published an innovative study about how well autistic and non-autistic adults can predict their own cognitive and social cognitive performance.
Back in January, a news story was published about Kerrianne’s study showing improved social interaction outcomes for autistic adults when paired with another autistic partner.
A detailed thread about the study and a link to the paper can be found here (feel free to DM me your email address if you’d like a copy of the full paper for this study or any of our studies):
In our new paper out today, autistic adults held a \u201cget to know you\u201d conversation with an unfamiliar autistic or typically-developing (TD) person. We were curious: would social interaction outcomes differ when their partner was also autistic? THREAD https://t.co/4koqUKV9G1
— Noah Sasson (@Noahsasson) December 11, 2019
Another paper published early in 2020 (it appeared a few months earlier online) showed that traditional standalone tasks of social cognition are less predictive of functional and social skills among autistic adults than commonly assumed in autism research.
How well does social cognition predict functional and social skills in autism? Our new paper attempts to answer this question. This thread summarizes why we conducted the study, what we found, and why I think it\u2019s important. https://t.co/KB1nIpK0M2
— Noah Sasson (@Noahsasson) August 16, 2019
Next, @kmdebrabander led and published an innovative study about how well autistic and non-autistic adults can predict their own cognitive and social cognitive performance.
New by @kmdebrabander and our lab: Autistic adults don\u2019t differ from non-autistic adults in the accuracy of their self-assessment on general cognitive tasks but are less accurate on social cognitive tasks. This however was unrelated to social functioning https://t.co/0MrqMKKO0r
— Noah Sasson (@Noahsasson) September 20, 2020
Sarcomeres in cardiac myocytes (heart muscle cells) are mechanically coupled to focal adhesions through dorsal stress fiber-like structures. #cardiotwitter #CellBiology
1/13
A thread based on Figure 1
A mature adult cardiac myocyte is packed with sarcomeres, whose contractile forces are coupled to the extracellular environment. With sarcomeres so close to the plasma membrane, how can we study the nature of this coupling?
2/13
Short answer: find a model system where the sarcomeres are not so close to what the cardiac myocyte is attached to. Enter, iPS cell-derived cardiac myocytes. These are “immature” in culture as they resemble fetal or neonatal cardiac myocytes.
3/13
Our previous work on iPS cardiac myocytes reported that sarcomere containing myofibrils assembled on the top surface of the myocyte.
https://t.co/xIBCu3hG1W
4/13
The sarcomeres seemed to be connected to focal adhesions on the bottom of the cell by thin actin bundles that resembled the dorsal stress fibers (DSF) commonly found in non-muscle cells. This movie steps through a Z stack of a myocyte starting at the bottom of the cell.
5/13
1/13
A thread based on Figure 1
A mature adult cardiac myocyte is packed with sarcomeres, whose contractile forces are coupled to the extracellular environment. With sarcomeres so close to the plasma membrane, how can we study the nature of this coupling?
2/13
Short answer: find a model system where the sarcomeres are not so close to what the cardiac myocyte is attached to. Enter, iPS cell-derived cardiac myocytes. These are “immature” in culture as they resemble fetal or neonatal cardiac myocytes.
3/13
Our previous work on iPS cardiac myocytes reported that sarcomere containing myofibrils assembled on the top surface of the myocyte.
https://t.co/xIBCu3hG1W
4/13
The sarcomeres seemed to be connected to focal adhesions on the bottom of the cell by thin actin bundles that resembled the dorsal stress fibers (DSF) commonly found in non-muscle cells. This movie steps through a Z stack of a myocyte starting at the bottom of the cell.
5/13
