BC HEALTH
Saved by @Alex1Powell

I disagree with you, Alastair. I believe @PanData19 is filling in the gaps that governments have failed to fill. I encourage you to have an open mind and listen intently to what we have to say. 1/n

 Here’s how @PanData19 is approaching this crisis differently from governments:
We believe that "health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity."- @WHO 2/n
To tackle the problem holistically, we have formed a multidisciplinary team made up of immunologist, microbiologist, geneticists, data scientists, physicians, economist, psychologists, educators, public health professionals and business owners. 3/n
We have also backed ourselves with a scientific advisory board made up of prominent experts in their fields.
@MartinKulldorff
@SunetraGupta
@MLevitt_NP2013
@MichaelYeadon3
#JayBhattacharya
#SucharitBhakdi
They are supporting us every step of the way. 4/n
We believe that "the right to health is one of a set of internationally agreed human rights standards, and is inseparable or ‘indivisible’ from these other rights.” @WHO 5/n
First, the right to health includes all health conditions. As a consequence, we care to reduce total harm resulting from the pandemic not just deaths with COVID. We care about cancer patients and heart patients. We care about mental health and suicide. 6/n
@ProfKarolSikora
We also don't see a dichotomy between lives and livelihoods. These aspects of our existence are intermingled. Loss of livelihood leads to loss of wellbeing and sadly sometimes to the loss of life. 7/n
Second, since preserving the right to health is indivisible from preserving other human rights, then we must care about all human rights:
a) the right to life
b) the right to liberty & security
c) respect to private and family life
d) freedom of opinion, speech and choice
8/n
e) freedom of assembly and association
f) protection from discrimination
g) the right to work and provide for one's family
h) the right to education
i) the right to move freely
9/n
We believe that public health measures must be put in place to support individuals not coerce them & deny them their basic human rights. Lockdowns, border & school closure, mandatory PPE, mandatory vaccines, & immunity passports should all be rendered unconstitutional. 10/n
We believe that all stakeholders in a crisis must collaborate to find a targeted solution. Complex problems can only be solved through a decentralized problem-solving process. The best solutions to global problems are local solutions. 11/n
For this reason, we have endeavoured to form a global network of doctors, lawyers & grassroots organizations, spreading from the US to Australia. As we each tackle this problem from a different angle, we believe our collaboration will amplify our voices & make them be heard. 12/n
We believe that interventions should be based on needs. The #GBdeclaration takes into account the age-gradient of risk posed by the virus and proposes a Focused Protection approach. 13/n
https://t.co/8NVPHs7H5X
We believe that blanket solutions lead to a situation where the cure is far worse than the disease.
The public deserves to be empowered with accurate and unbiased information to make informed decisions not scared and fearmongered into compliance. 14/n
We believe in human agency. People are the experts at making decisions that optimize their wellbeing and health. We don't believe that those at the top can make better decisions for those at the bottom. 15/n
We believe in explanation-based science over inductive methods. Evolutionary knowledge is built on conjectures and refutations. This process relies on scientific debate. Shutting down alternative views and demonizing criticism is denying science and ending human progress. 16/n
We believe in real-life data over modelling exercises that rely on false assumptions. Assuming that all people are susceptible to a 'novel' virus and that they all carry an equal risk from it can lead to pretty disastrous predictions and actions. 17/n
Postulating that lockdowns have a positive effect on mortality then proving this theory by claiming that lives were saved by the lockdowns in comparison to the atrocious predictions of the modellers is unscientific and defeats common sense. 18/n
We believe the truth will prevail.
To end this fiasco,
We must all come together now to reopen our societies.
We must all come together to reverse the collateral damage and reduce total harm.
We must all come together to save our civilization. 19/n
@wodarg
@PanData19 is proud to be a major contributor to overcoming this challenge. We are hard at work on a blueprint that will pave the way ahead.
We will soon publish our Protocol for Reopening Society on our website. Stay on the lookout! 20/n
https://t.co/uN5Pj9DaHB

More from Abir Ballan

Abir Ballan \U0001f60a
Abir Ballan 😊
@abirballan
Heart-breaking harsh reality.
Not only did we prevent kids from proper education, denied them to play in the park or swim in the sea, asked them to wear masks, not touch or play with their friends,...

and caused them scaring psychological harm from safetyism, we are also physically injuring them.
How can we not see the plight of the children? 2/n

“number of children under one presenting with fractures & head trauma since September has more than doubled compared to the same period the previous year. It's normal for parents to feel overwhelmed sometimes. But serious injuries can happen in just a few sec. of frustration.”3/n

@nedaamani @strauss_matt @CIMAdoctors @OnCall4ON @CPHO_Canada @CMOH_Alberta
@denisrancourt @randyhillier
#Canada #Ontario @barbcraig7 @CdnAdvocacy @myfreedom2017 @roccogalatilaw @JustinTrudeau
4/n

"we know that the accompanying illness, death, social isolation and malnutrition will have deep and lasting impacts on our children and adolescents"
SOCIETY
Abir Ballan \U0001f60a
Abir Ballan 😊
@abirballan
"Obedience is the biggest threat to mankind"
"Disobedience keeps society free"
"The question is not why people rebel but why people don't rebel"
In socialist countries, "They obeyed laws that were

https://t.co/vZ06ujkt0F


https://t.co/kwzjkU6PEm


https://t.co/4DFOHkjW76


https://t.co/KdvyM3UYTo
SOCIETY
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Abir Ballan \U0001f60a
Abir Ballan 😊
@abirballan
A brief tutorial in health education to show you how sound health education models have been used for manipulation instead of creating health awareness during the COVID 19 pandemic. We'll uses masks as an example of a health behavior.
Are you ready to explore? 1/n

The Health Belief Model (HBM) consists of 5 components: perceived threat (lethality + Susceptibility),
perceived benefits,
perceived barriers and
cues to action.

Familiarise yourself with the definition of each concept in this table. 2/n
https://t.co/1tOz1cJFvc


Study this diagram to understand how the components are interrelated. 3/n
https://t.co/iUoaqNkgyP


Now let’s apply this to the COVID 19 pandemic.
Review this diagram to see how the HBM applies to the behaviour of mask-wearing.
“perceived susceptibility appeared to be the most significant factor determining compliance” 4/n
https://t.co/xF6uwUx12N


Part I: The HBM
Increase the perceived threat of a disease
1) increase perceived severity: Confusing the general public with CFR & IFR- 2 indicators that are an order of magnitude apart.
People understood wrongly that the fatality rate of C19 is
CATEGORY C19 , CETEVORY C19
Abir Ballan \U0001f60a
Abir Ballan 😊
@abirballan
"If you then discovered that the majority of the committee members had financial interests in the drug being developed, how would you feel?" 1/n
@zoeharcombe @RosemaryFreiTO @simondolan @Francis_Hoar @BreesAnna @toadmeister @NeilClark66 @allisonpearson

#KBF
"The advice was stay home if you’re sick, wash your hands, protect the vulnerable, most people will have a mild illness, wearing face masks is “usually quite a bad idea“, & “big gatherings don’t have a big effect so we don’t want to disrupt people’s lives.” 2/n

"1) Organisations invested in vaccines make money from vaccines. If people acquire natural immunity, they have reduced or no need for a vaccine and thus the potential gain for the vaccine company is reduced." 3/n

"2) Locking people in their homes and other lockdown measures will reduce the number of people who acquire natural immunity." 4/n

"The notable exception was that @neil_ferguson resigned from the SAGE committee when it became known (on 5th May) that he had broken lockdown rules" 5/n
SOCIETY
Abir Ballan \U0001f60a
Abir Ballan 😊
@abirballan
The ten points of the Nuremberg Code
1) The voluntary consent of the human subject is absolutely essential.

2) The experiment should be such as to yield fruitful results for the good of society, unprocurable by other methods or means of study, and not random and unnecessary in nature. 2/n

3) The experiment should be so designed and based on the results of animal experimentation and a knowledge of the natural history of the disease or other problem under study that the anticipated results will justify the performance of the experiment. 3/n

4) The experiment should be so conducted as to avoid all unnecessary physical and mental suffering and injury. 4/n

5) No experiment should be conducted where there is an a priori reason to believe that death or disabling injury will occur; except, perhaps, in those experiments where the experimental physicians also serve as subjects. 5/n
FOR LATER READ

More from Health

Santiago
Santiago
@svpino
You gotta think about this one carefully!

Imagine you go to the doctor and get tested for a rare disease (only 1 in 10,000 people get it.)

The test is 99% effective in detecting both sick and healthy people.

Your test comes back positive.

Are you really sick? Explain below 👇

The most complete answer from every reply so far is from Dr. Lena. Thanks for taking the time and going through


You can get the answer using Bayes' theorem, but let's try to come up with it in a different —maybe more intuitive— way.

👇


Here is what we know:

- Out of 10,000 people, 1 is sick
- Out of 100 sick people, 99 test positive
- Out of 100 healthy people, 99 test negative

Assuming 1 million people take the test (including you):

- 100 of them are sick
- 999,900 of them are healthy

👇

Let's now test both groups, starting with the 100 people sick:

▫️ 99 of them will be diagnosed (correctly) as sick (99%)

▫️ 1 of them is going to be diagnosed (incorrectly) as healthy (1%)

👇
HEALTH
Aureliano Stingi
Aureliano Stingi
@AurelianoStingi
Controversial 3D. Probably none of you knows about Leber congenital amaurosis type 10, congenital blindness that affects 3 out of 100,000 children, condemning them to blindness for life. The only possible treatment is through gene therapy. 1/n


Thanks to Crispr-CAS9 technology we MODIFY the defective gene inside the patient eye ( they directly inject the treatment into the eye). Before CRISPR the treatment was based on Adenovirus carrying the correct form of the gene

In both cases, we MODIFY the patient DNA and that's the only way (today) to treat this disease. LCA10 is not the only genetic disease affecting kids unfortunately the list is long and the variety of diseases is terrifying.

Now think about a parent with a kid with a genetic disease, he/she would try and do anything to save him/her. ANYTHING and they would take some RISKS, gene therapy was a risk at the beginning, and any new experimental treatment shares a percentage of risk. 4/n

Now we come to #COVID19 and #vaccines. The new RNA vaccines are a HUGE scientific breakthrough, that may open new amazing therapeutic paths. And like ANY other human activity share a risk.
HEALTH
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\u2744\ufe0fI'm A Fuckin' Princess\u2744\ufe0f
❄️I'm A Fuckin' Prince...
@Just_ReneaR
I'm not pro-murdering babies.
I'm pro-Becky who found out at her 20 week anatomy scan that the infant she had been so excited to bring into this world had developed without life sustaining organs.
HEALTH
Pete Wharmby
Pete Wharmby
@commaficionado
Once again I'm reminded that every action has an equal and opposite reaction. The recent push by a large number of autistic people to 'own' their diagnosis and try to raise acceptance and dispel harmful myths has kicked up a minority of autistic people to fight against this.

This may seem bizarre - who fights against improved acceptance? - but actually has clear roots in the ongoing culture war the West seems engaged in. The identity positive autistic movement, of which I am a part, is viewed by some as another manifestation of 'wokeness'.

This is the right-wing definition of 'wokeness', of course - ie a modern equivalent of the pejorative take on political correctness, but it's definitely at the core of this 'neurorealist' movement - the idea the autistic community is being hijacked by 'woke lefties'.

They believe that the push for acceptance of neurodiversity and rejection of the medicalisation of autism is misguided and drawing attention away from those autistic people who, in their view, need more help and intervention.

The trouble is, this view is pretty much baseless. Firstly, there is little evidence that autistic advocates who push for acceptance are in any way harming autistic people who require more help and support. Second, the view effectively silences those of us who are able to share.
HEALTH
Avraham Z. Cooper, MD
Avraham Z. Cooper, MD
@AvrahamCooperMD
1/15
Why can cefepime cause neurological toxicity?

And why is renal failure the main risk factor for this complication?

The answer requires us to learn about cefepime's structure and why it unexpectedly binds to a certain CNS receptor.

#MedTwitter #Tweetorial


2/
Let's establish a few facts about cefepime:

🔺4th generation cephalosporin antibiotic
🔺Excretion = exclusively in the urine (mostly as unchanged drug)
🔺Readily crosses the blood-brain barrier (so it easily accesses the brain)

https://t.co/rjYG1BfGPR


3/
The first report of cefepime neurotoxicity was in 1999.

A patient w/ renal failure received high doses of cefepime and then developed encephalopathy, tremors, myoclonic jerks, and tonic-clonic seizures.

✅All symptoms resolved after hemodialysis.

https://t.co/u7JLVitQpp


4/
Cefepime neurotoxicity is surprisingly common, occurring in up to 15% of treated critically ill patients (w/ symptoms varying from encephalopathy to seizures).

💡The main risk factors = renal failure and lack of dose adjustment for renal function.

https://t.co/nxbnzSq8AR


5/
What about cefepime induces neurotoxicity?

One clue is that it's not the only antibiotic that causes neurotoxicity, particularly seizures.

This actually is a class effect w/ other beta-lactam antibiotics (including penicillins and carbapenems).

https://t.co/Lf4BhON9IY
HEALTH

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Delilah S. Dawson
Delilah S. Dawson
@DelilahSDawson
Hello, writers! How about a thread on LITERARY AGENTS? How to get one, how to talk to one, how to keep one happy. Spoiler alert: I am 100% pro agent and can't imagine not having one on my side. 1/

Why would you want a literary agent?
* you want to be traditionally published
* you want someone experienced to help guide your career
* you want to learn how to edit like a pro
* you want to sell foreign and movie rights
* you want answers to your newbie questions 2/

Why you might *NOT* want a literary agent:
* you want to self publish
* you're not willing to compromise on your edits
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I... can't think this way. Literary agents have been crucial to my career. 3/

So, how do you get a literary agent?
1. Have a finished, revised, edited, polished manuscript.
2. Write a query letter for your book
3. Send your query to agents who rep your genre and are open to submissions
4. Repeat steps 1-4 until you're offered representation. 4/

So, let's go through those four steps. First of all, you must have a finished, revised, edited, polished book, and it must be sellable. That is, you can't sell a 600k picture book or a 40k adult Fantasy, etc. You must read extensively in the genre you're writing. 5/
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Dr. Anandibai Joshi

Upon her birth on 31 March 1865 she was named Yamuna, after the holy river. Her parents Gunputrao Amritaswar Joshee & Gungabai Joshee came from a long lineage of wealthy landlord family in Kalyan of Bombay Presidency, whose wealth was now waning.


Anandi was the sixth of 10 children, & had 4 brothers (only two of which survived) & five sisters. Her father was particularly fond of her, as she was a bright child with an inquisitive mind. Being an educated man himself, Ganpatrao assured that his daughter was taught Marathi.

As was common practice she was married at a tender age of 9, to Gopalrao Joshi, a 29 year old widower who worked as a postal clerk in the same city. After marriage her husband named her ‘Anandibai’ (which means ‘Joy of my heart’).

Gopalrao was man ahead of his times with reformist ideas & had married Anandibai on the condition that he would be allowed to educate his wife.

He even tried to enroll Anandi in a missionary school, but did not succeed. Despite being the supportive husband, Gopalrao had his flaws.

He was a strict teacher & would sometimes resort to beating if Anandi slacked in her studies.
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Aron Hyman
@aron_hyman
THREAD: The following tweets are for the purposes of stories that will appear in Sunday Times Daily. The videos and images depicted may be upsetting but are deemed to be in the public interest. This is the story of the Ayanda "Borhey" Mtila as far as we were able to verify it.


On 13 October Mtila as defacto overlord of the Boko Harram gang, allegedly carried out his penultimate cash-in-transit robbery. Sources say he sustained a head wound in a shootout with security guards. Some friends believe he was killed by a fellow

He died two days later, on 15 October, after allegedly being in a coma for more than a day. His funeral was a spectacle, held on Nyanga Sports fields on 24 October and attended by hundreds of people. Sources say it was made possible by Paarl businessman Lukhanyo "Spur" Mangena.
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Dr. Thomas Binder, MD
Dr. Thomas Binder, MD
@Thomas_Binder
1/12

RT-PCR corona (test) scam

Symptomatic people are tested for one and only one respiratory virus. This means that other acute respiratory infections are reclassified as


2/12

It is tested exquisitely with a hypersensitive non-specific RT-PCR test / Ct >35 (>30 is nonsense, >35 is madness), without considering Ct and clinical context. This means that more acute respiratory infections are reclassified as


3/12

The Drosten RT-PCR test is fabricated in a way that each country and laboratory perform it differently at too high Ct and that the high rate of false positives increases massively due to cross-reaction with other (corona) viruses in the "flu


4/12

Even asymptomatic, previously called healthy, people are tested (en masse) in this way, although there is no epidemiologically relevant asymptomatic transmission. This means that even healthy people are declared as COVID


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Deaths within 28 days after a positive RT-PCR test from whatever cause are designated as deaths WITH COVID. This means that other causes of death are reclassified as
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Noah Smith
Noah Smith
@Noahpinion
1/People I know on the Right tend to be obsessed with the idea of "crimethink", taboos, and the (supposedly) oppressive, omnipresent enforcement of liberal cultural norms.

Why?

My new theory: A lot of it is guilt.

2/It's true that in some circles - the media, universities, many big corporations - liberal norms *are* enforced to some degree, and the enforcement has probably gotten stronger in recent years.

But I don't think this explains all of the Right's obsession.

3/The stereotype is that people on the Right tend to be more threat-sensitive. That would help explain the perception that liberal norm-enforcers are lurking everywhere, ready to pounce and anathematize anyone who makes a misstep.

But I don't think that's all of it either.

4/And of course, it's always fun - whether you're on the Right or the Left, or playing a video game, or whatever - to style yourself as the brave iconoclastic rebel fighting against the oppressive forces of blah blah blah.

But I don't think this is all of it, either.

5/The reason I think it's more than these things is that even *in private*, people on the Right express their "crimethink" ideas very gingerly and hesitantly.

I get the sense that they're not just afraid of external censure, but have also internalized liberal norms.
SOCIETY