Once again I'm reminded that every action has an equal and opposite reaction. The recent push by a large number of autistic people to 'own' their diagnosis and try to raise acceptance and dispel harmful myths has kicked up a minority of autistic people to fight against this.

This may seem bizarre - who fights against improved acceptance? - but actually has clear roots in the ongoing culture war the West seems engaged in. The identity positive autistic movement, of which I am a part, is viewed by some as another manifestation of 'wokeness'.
This is the right-wing definition of 'wokeness', of course - ie a modern equivalent of the pejorative take on political correctness, but it's definitely at the core of this 'neurorealist' movement - the idea the autistic community is being hijacked by 'woke lefties'.
They believe that the push for acceptance of neurodiversity and rejection of the medicalisation of autism is misguided and drawing attention away from those autistic people who, in their view, need more help and intervention.
The trouble is, this view is pretty much baseless. Firstly, there is little evidence that autistic advocates who push for acceptance are in any way harming autistic people who require more help and support. Second, the view effectively silences those of us who are able to share.
The argument seems to be, if you're capable of actively advocating, then you're not really autistic - at least not autistic *enough* for your opinion to matter. This is an obvious nonsense in itself, as it is so generalised as to be useless to anyone, but also ignores key things.
For example, it assumes that autistic people who can advocate online in text are somehow highly capable generally. This is simply not true. Many of us are acutely affected by being autistic, fighting executive function issues, massive anxiety and depression.
Autistic advocates online are *online*. There's a reason the movement has only managed to take off since the development of social media - it gives those of us with communication disabilities an opportunity to speak. These 'neurorealists' deny us that.
They claim the very act of advocacy shows we can't speak for those we advocate for, which causes a serious logical regression that ultimately means no one can ever advocate for anyone. They know this, or at least i hope they do. But they don't care.
This is because their agenda is simply to squash any sign of progressive identity politics, because it goes against their political ideology, as far as I can tell. There are other motivations - shady links to ABA and the 'autism mom' phenomenon (there's a *lot* of money there.)
But ultimately there's just an intolerance of autistic people taking control of the narrative; a hatred of the idea that autism could just be another way of being. Insistance it is a disease, an illness that ruins lives.
I could go on but frankly it's exhausting. I've got most of these people blocked or muted as they rarely argue in good faith. If anyone wants to add to this to fill out my points, please do - I'm not the font of all knowledge on this!
Just so you know, my feelings towards these individuals are pretty strong. They've caused me personally a lot of misery over the last few years, but that's nothing compared to the cumulative harm they've done to the autistic community. I really don't like them.
The takeaway here is that not all autistic people view 'neurodiversity' as a good thing. Also, that not all autistic people argue in good faith. I've been accused of not being autistic by more other autistic people than non-autistic folk, and that's disturbing to me.
We autistics can have a tendency - and it's rooted in positivity - to idealise our community and blame neurotypicals for our ills. But it's not as simple as that.

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1/16
Why do B12 and folate deficiencies lead to HUGE red blood cells?

And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?

For answers, we'll have to go back a few billion years.


2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.

Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine

But why does DNA contains thymine (T) instead of uracil (U)?

https://t.co/XlxT6cLLXg


3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).

In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?

https://t.co/bIZGviHBUc


4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.

DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.

https://t.co/bIZGviHBUc


5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.

When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.

[*Note: thymine is the base in dTMP]

https://t.co/AnDUtKkbZh
Some thoughts on this: Firstly, it might be personal preference, but I am not keen on this kind of campaign as I feel like it trivialises cancer. Sometimes the serious message gets lost because people are sharing pics of cats or whatever and the important context is gone.


More importantly, the statistic being used in the campaign is misleading. It says 57% of women put off cervical screening if they can't get waxed. But on further investigation, that's not accurate.

The page here goes on to say "57% of women who regularly have their pubic hair professionally removed would put off attending their cervical screening appointment if they hadn’t been able to visit a beauty salon."

So the 57% represents a concern not across the whole population of women, but only those who regularly get waxed. So how big of an issue is this across the whole population? And what else is stopping people getting smears?

I think campaigns for cancer screening are really tricky because there is so much nuance that often doesn't fit into a catchy headline or hashtag. It's certainly not easy and is part of a bigger conversation.

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