BC CATEGORY C19
Saved by @vliscony

1/: Scientific integrity is a valuable commodity. What happens when external funders take influence on both scientific™ findings and media coverage can be seen in the current global crisis. It is time to return to the fundamental principles of science: ⬇️A thread⬇️

 2/: In this thread, I will roughly explain why #empiricism and #repeatability are important factors for science and why model approaches should be interpreted with caution (and that is what I am saying as a modeller).
3/: I am aware that the principle of science is far more profound than explained in this thread, but this thread is written for laymen on @twitter and not for the lecture room. Also, within the scientific community, there is no clear consensus about this topic either.
4/: In recent years, I have been working on complex food production systems that increase food production and show high nutrient and water use efficiencies. I have thus been involved in plant growth experiments and holistic system modelling activities (@MATLAB, @AnyLogicCo).
5/: The plant growth experiments included environmental factors, #metagenomics (i.e. microbial genome sequencing), flow regulations etc. and the modelling covered the prediction on non-existing systems based on experimental and literature data.
6/: The IMHO most important principle of science is #empiricism. Empirical evidence is information that verifies the truth (which accurately corresponds to reality) or falsity (inaccuracy) of a claim. However, experiments and observations usually do not represent the "truth".
7/: There can be many intervening factors that have an impact on the observations. The less the conditions are controlled, the higher the deviations. So in order to “find the truth”, one wants to conduct an experiment in an environment with as few as possible inference factors.
8/: I will explain this through the example of my plant growth experiments. One can conduct the experiment in a greenhouse; solar radiation, humidity, temperature etc., are no stable factors. However, in a “climate chamber”, all of these factors can be standardized.
9/: This allows us to compare experiments with one another much easier. But there are also other factors that are not easy to control. These are (often) the genetic diversity of plant species, microbiological characteristics of the process water etc.
10/: This brings us to the point to talk about #repeatability. First of all, it’s essential that an experiment should contain several replications (or, if not possible repetitions) and control groups to ensure a high statistical relevance with respect to the made observations.
11/: However, the results are fundamentally dependent on the many factors, which have a decisive influence on the experiment’s outcome. I will give you two examples to explain what I mean: (a) my experiences with plant growth experiments; (b) vitamin D #COVID trials.
12/: In one experiment, we observed that lettuce grew much faster (40%) when being grown in aquaculture-derived water that contained many bacteria (i.e. which was not sterile such as it is the case for hydroponics systems). https://t.co/WBMyfb5v8k
13/: I repeated this experiment in different locations repeatedly, and the results seem to differ (still, we always see a growth advantage). This has to do with environmental conditions, different microbial strains in the process water, different seed material/quality etc.
14/: So what’s the truth? I don’t know. Why don’t I know? Because it depends. What does it depend on? Well, many factors.

And plant growth experiment cannot be considered complex compared to the field of epidemiology or alike, where it’s even harder to control conditions.
15/: I was able to make similar observations regarding vitamin D studies. Many studies have been conducted in this field, and they are everything but uniform, also due to different hypotheses. An overview of conducted vitamin D studies can be found here: https://t.co/zhzTWwF9br
16/: In general, we can see that vitamin D has a high impact on the severity of the course of COVID, the death rate etc. And yet, meta-analyses generally compare apples and oranges (which is often unavoidable, so there is nobody to blame). https://t.co/YgJJNwMfzE
17/: The approach of every study differs in the following approaches: (1) amount IU of vitamin D administered; (2) time of administration; (3) physical characteristics of the patients; (4) selection of individuals; (5) dietary co-factors; etc. just to name some.
18/: There are, for example, studies out there that claim that vitamin D doesn't have an impact on COVID. Those studies, however, assume that a sufficient vitamin D blood serum level lays around 20 ng/mL, which is a completely faulty assumption. Still made it through peer review.
19/: Such drawn conclusions can cause confusions, and it’s the scientific community’s job to analyse, verify, and discuss findings. Such open discussions (which should include transparent peer-review processes) would help us to reduce biases. https://t.co/c1ONzsVMWC
20/: After having given you a brief insight into #empiricism and #repeatability, I want to talk about the field of modelling. During this 'pandemic', the outcome of models, again and again, justify political restrictions. But how does modelling work?
21/: The objective of a prediction model is to predict the future on the basis of available or predicted data. Often, complex situations have to be simplified for a model to work.
22/: In the last couple of months, we came across many modelled predictions: almost all of them were completely wrong (remark: don’t let physicists work in the field of epidemiology). Issues such as #seasonality have been purposely neglected, which is a methodological failure.
23/: Comparing the model prediction with the actual observations is called “model validation”. Every serious scientist should validate their models and publicly discuss why the model failed or was able to predict the future. This is somehow not the case anymore.
24/: It would be exciting to get to know why @ViolaPriesemann, @EricTopiol, @CorneliusRoemer, @neil_ferguson, or @VSPTUBerlin (who are traffic planners lol) do not validate their COVID-models but instead keep on publishing doomsday scenarios with their faulty work.
25/: It is also useful to illustrate complex relationships in so-called causal-loop diagrams prior to blindly modelling a situation. That is at least what I do (see graphic for Kombucha).
26/: A holistic causal loop diagram demonstrating the complexity of the pandemic environmental–health–socio–economic system can be found in this publication: https://t.co/CpCL4wMq2b. This could for example be a solid basis for a holistic model (consisting of several submodels).
27/: Every serious scientist should keep on questioning the “reality” and his/her own work. I can only recommend the mentioned “scientists” and many other modellers to read the following article. https://t.co/UBoPEliLiL
28/: I also have another shout-out to the media: why do you keep on giving scientists a platform that have been wrong several times.
29/: … are openly lying... https://t.co/nPKyuGTr63
30/: … committed scientific fraud… (hello @Eurosurveillanc & @StephenABustin)
https://t.co/1m7rpVqYFQ
31/: … let their bachelor students do the modelling job…
https://t.co/5hLDktlvf8
32/: … lack of a scientific degrees…
https://t.co/pMIGbbKrLU
33/: … make false statements… (plus get funded by #Soros, @wef and @WHO; i.e. conflict of interests)
https://t.co/nElSOLHMUd
34/: … defame genuine colleagues…
https://t.co/h78oX9Ah3a
35/: … have conflicts of interests… (best wishes to the @gatesfoundation). etc.
https://t.co/2AzbGs4KDT
36: Also, the #TeamScience that the media talks about is much bigger than assumed. Critical voices are disregarded or discredited. Instead, those who are in line with the agenda (no matter how unscientific their approach is) are presented as “THE SCIENCE™” we should listen to.
37/: Last but not least, John Ioannidis wrote one of the most important publications of the last decades about this topic: “Why Most Published Research Findings Are False”. Give it a go because he is part of the real #TeamScience. https://t.co/LeGCfIMHFf

More from Dr. Simon ツ

Dr. Simon \u30c4
Dr. Simon ツ
@goddeketal
1/: The Nuremberg Code is a set of research ethics principles for human experimentation created as a result of the Nuremberg trials at the end of the Second World War. In light of the current events, they are more actual than ever before. ⬇️an important thread⬇️


2/: These so-called ‘Doctors’ Trial’ focused on physicians who conducted #inhumane and #unethical human experiments in German concentration camps, in addition to those who were involved in over 3,500,000 sterilizations of German citizens. (the picture shows doctors/criminals)


3/: Ten points of the code were given in the section of the verdict entitled "Permissible Medical Experiments". They can be found in detail on the following website:

4/: Point #1 means that the person involved should have legal capacity to give consent; should be so situated as to be able to exercise free power of choice, without the intervention of any element of force, fraud, or deceit.


5/: Using an insufficiently-tested vaccine on humans is unethical. However, as long as people voluntarily consent to receive the vaccine, being informed about all risks, everything is OK. Doing this with force, however, is against the Nuremberg Code.
CATEGORY C19
Dr. Simon \u30c4
Dr. Simon ツ
@goddeketal
1/: Avicenna was a Persian scientist, who lived 1000 years ago. He put two lambs in separate cages, which had the same health conditions. But only one lamb could see a wolf that was put in a third cage. The observations were astounding. (h/t @farmer_student) ⬇️a thread⬇️


2/: Both lambs were provided with the same feed. Also, the weight was exactly the same when the experiment started. Several months later, the lamb with sight on the wolf became cranky, restless, weak, and showed a significant weight loss and signs of poor development.

3/: The lamb that was under chronic stress as it was placed in a situation of constant apparent danger died eventually. 🐑🪦 In fact, the wolf did not pose a danger at all, but this was beyond the lamb's perception.

4/: This experiment showed that increased levels of the stress hormone cortisol have a bad impact on the metabolism of mammals. And 1000 years after this experiment, we are facing a similar situation again but with the difference that we are aware of the impact of stress.

5/: Currently, we are overwhelmed with medial and governmental propaganda with respect to a common cold virus (that might hypothetically be more lethal though) that doesn't do harm to the majority of the people. Extreme global measures are taken.
CATEGORY C19
Advertisement
Dr. Simon \u30c4
Dr. Simon ツ
@goddeketal
Substantial analysis of @BenMarten regarding the mortality in Germany. Particularly noticeable is the "excess mortality" in December. Ben states that "lockdown deaths" could play an important role here. I would like to elaborate my thoughts on that. ⬇️Mini-Thread⬇️


Factor 1: Vitamin D deficiency.

Many people (especially elderly) have been locked in during the summer. Also the majority of holiday trips have been cancelled, leading to a lower 25(OH)D blood serum level as usual. The body can store vitamin D up to several months.


As vitamin D is a hormon that modulates the immune responses, we can assume that the lockdown measures had some adverse effect on our immune system. Especially elderly people in retirement homes must have been severely affected.

Factor 2: Loneliness

"Loneliness, it seems, can lead to long-term "fight-or-flight" stress signaling, which negatively affects immune system functioning. Simply put, people who feel lonely have less immunity and more inflammation than people who

Factor 3: Hyper Hygiene

Constant disinfections and high hygienic standards weaken the immune system. It gets literally "out of
WORLD
Dr. Simon \u30c4
Dr. Simon ツ
@goddeketal
1/ One year of destroyed economies, social isolation & deep social splits calls for an anniversary ⬇️thread ⬇️ to celebrate the RT-qPCR manuscript by Christian Drosten (@c_drosten) & Victor Corman (@vmcorman), submitted on 21st Jan 2020 to @Eurosurveillanc. #UnbiasedScience


2/ Before this very publication, virologists were neither treated like superstars, nor were they considered icons or half-gods. In 2009, Drosten almost succeeded in installing the false premise virology could supersede holistic medical sciences as discussed in this thread.

3/ Drosten is a virologist. He neither has any background in epidemiology, nor has he ever worked in the civil service. He also doesn’t have a background in public health. Yet he and his colleagues affect our daily lives to the level of whom to meet up or how to flush the toilet.


4/ Before January 2020, Drosten and Corman were common virologists at Charité Berlin, whenever they were not involved in economic implications (https://t.co/UTDwG8U7Du). Other than that, they looked at coronaviruses in dromedary calves in the Middle East or Africa. 😍 #cute


5/ Finally in Jan 2020, the published paper laid the theoretical grounds for the current pandemic, the RT-qPCR mass testing-religion, for which he was awarded his second German Federal Cross of Merit (he received the first one in 2005 for developing the SARS-CoV PCR test).
SOCIETY
Dr. Simon \u30c4
Dr. Simon ツ
@goddeketal
1/: The inventor of the corona PCR-Test @c_drosten is one of the #protagonists of the current crisis. He is known for involving himself in contradictions. In 2014, he gave a legendary #interview to @wiwo (https://t.co/jzTRh5Suhc) that I will address in this ⬇️short thread⬇️.


2/: The interview is significant because @c_drosten made totally sane statements back then that follow the principle of common sense. Considering his involvement in the "genesis of the current pandemic", his assertions appear in an entirely different


3/: In 2014, for instance, washing the hands was sufficient against being infected by coronaviruses. Several years he demands measures that destroy national economies and social life worldwide.


4/: Young @c_drosten also severely criticized the fact that Saudi Arabia used the PCR method to detect potential infections. From his point of view, that specific method could lead to many irrelevant cases. Nowadays, his view shifted his opinion towards 'collective punishment'.


5/: Whereas he demands "testing, testing, testing" nowadays and spreads panic and fear via (social) media, he heavily condemned that behaviour of Saudi media in 2014. On top of that, he expressed his concern that medial panic could increase the number of lab tests significantly.
CATEGORY C19

More from Category c19

Robin Monotti FRSA \u2b50
Robin Monotti FRSA ⭐...
@robinmonotti
PROBIOTICS & VIT D: "The vitamin D receptor is highly expressed in the gastrointestinal tract where it transacts gene expression..These results support the underlying hypothesis that the human gut microbiome and vitamin D metabolism are integrally related"
https://t.co/15rVFa1fkk


"Men with higher levels of 1,25(OH)2D and higher activation ratios, but not 25(OH)D itself, are more likely to possess butyrate producing bacteria that are associated with better gut microbial health."

"Several studies suggest that gut microbiota alter intestinal vitamin D metabolism (VDM), and probiotic supplements can affect circulating vitamin D levels."

"Because the serum 25(OH)D correlates with overall vitamin D storage, it is the preferred clinical measure to assess vitamin D sufficiency."

"Clinically, serum 25(OH)D levels ≥20 ng/ml are considered adequate while 25(OH)D levels <20 ng/ml are defined as vitamin D deficiency."
CATEGORY C19
Medical Nemesis
Medical Nemesis
@Medical_Nemesis
I am puzzled as to what the greatest medical scholar found in his research of smallpox vaccination.

/1


Legends and myths in medicine. Debunked. Not that but few care.

https://t.co/3Hu2D9Un0J

/2


https://t.co/xnZ2EXO1f5

/3


Open access.

Where have we seen this before? 🤔
CATEGORY C19
Advertisement
Dr. Simon \u30c4
Dr. Simon ツ
@goddeketal
1/: Avicenna was a Persian scientist, who lived 1000 years ago. He put two lambs in separate cages, which had the same health conditions. But only one lamb could see a wolf that was put in a third cage. The observations were astounding. (h/t @farmer_student) ⬇️a thread⬇️


2/: Both lambs were provided with the same feed. Also, the weight was exactly the same when the experiment started. Several months later, the lamb with sight on the wolf became cranky, restless, weak, and showed a significant weight loss and signs of poor development.

3/: The lamb that was under chronic stress as it was placed in a situation of constant apparent danger died eventually. 🐑🪦 In fact, the wolf did not pose a danger at all, but this was beyond the lamb's perception.

4/: This experiment showed that increased levels of the stress hormone cortisol have a bad impact on the metabolism of mammals. And 1000 years after this experiment, we are facing a similar situation again but with the difference that we are aware of the impact of stress.

5/: Currently, we are overwhelmed with medial and governmental propaganda with respect to a common cold virus (that might hypothetically be more lethal though) that doesn't do harm to the majority of the people. Extreme global measures are taken.
CATEGORY C19
Brumby
Brumby
@the_brumby
This will be my first and possibly last tweet (thread) as I am mostly here to learn. It is prompted by a recent study questioning lockdown efficacy that is getting a lot of attention. It appears people believe it to be the first of its kind, but I have been collecting similar

studies since March 2020. Below are 30 published papers finding that lockdowns had little or no efficacy (despite unconscionable harms) along with a key quote or two from each:

1.https://t.co/VseXe862AX

“there is no evidence that more restrictive nonpharmaceutical interventions (“lockdowns”) contributed substantially to bending the curve of new cases in England, France, Germany, Iran, Italy, the Netherlands, Spain, or the United States in early 2020”

2.https://t.co/EzTSzeZyue

“Inferences on effects of NPIs are non-robust and highly sensitive to model specification. Claimed benefits of lockdown appear grossly exaggerated.”

3.https://t.co/4c4LqeQ5bz

“government actions such as border closures, full lockdowns, and a high rate of COVID-19 testing were not associated with statistically significant reductions in the number of critical cases or overall mortality”
CATEGORY C19
Ken McCarthy
Ken McCarthy
@KenMcCarthy
It's all here folks...How the CoVid Con was 37 years in the marking

3/4
https://t.co/WBAnAUO0UU
CATEGORY C19

You May Also Like

Manas Arora
Manas Arora
@iManasArora
My course is now available for FREE on youtube.

Channel link: https://t.co/BJqESqFVko
ALL
TXgrlWatching\U0001f4bb\u2694\U0001f6e1
TXgrlWatching💻⚔🛡...
@VeritasTXgem
Thread A History lesson for the MOAB:
1. The United States of America is not and has never been a Democracy, we're a Federal Republic tied together by the capital Laws of the Constitution.

Everyone in the country is about to get a harsh lesson on what this really means...

2. In 1871, February 21: Congress Passes an Act to Provide a Government for the District of Columbia, also known as the Act of 1871.

With no constitutional authority to do so, Congress creates a separate form of
government for the District of Columbia.

3. A ten mile square parcel of land (see,
Acts of the Forty-first Congress,” Section 34, Session III, chapters 61 and

4. The act — passed when the country was weakened and financially depleted in
the aftermath of the Civil War — was a strategic move by foreign interests
(international bankers) who were intent upon gaining a stranglehold on the coffers and neck of America.

5. Congress cut a deal w/ the international bankers(Rothschilds of London) to incur a DEBT to said bankers. Because the bankers were not about to lend money to a floundering nation w/out serious stipulations, they devised a way to get their foot in the door of the United States.
HISTORYLESSON
Advertisement
Anu Satheesh \U0001f1ee\U0001f1f3
Anu Satheesh 🇮🇳...
@AnuSatheesh5
#Guruvayur_Krishna_Bhakthi  🕉
#Guruvayur
#Storytime
Beautiful Story of Guruvayurappan

Poonathanam Namboothiri was a great devotee of Guruvayurappan. One day Poonthanam was going to Guruvayur Kshetram. It was night time and eventhough Namboothiri was tired he continued to walk


Suddenly some thieves came and blocked his way. Poonthanam cried for Shri Krishna to help. Thieves snatched all valuables from him, but Namboothiri holding his Bhaghavatam book called Shri Krishna to help. That time a man came in a horse back and fought with thieves and protected


Namboothiri. Poonthanam thanked Krishna for helping him from danger and said to the man that "Shri Krishna has send you here and I don't know how to thank you".  The man smiled and told that he is Mangattachan, minister of  samoodhiris. Poonthanam once again thanked him and


gave his ring to Mangattachan as a token of thanks and continued his journey. He reached Guruvayur early morning for Nirmalya Darshan. Temple poojari came near him and told that Guruvayurappan came in his dreams and asked to hand over the ring to poonthanam.


When he opened Kshetra Nada poonthanam was surprised to see his ring on Guruvayurappan, which he gifted to Mangattachan. He understood that it was Guruvayurappan who came as Mangattachan to protect him. This is how Bhagwan treat his devotees.

Hare Krishna
🙏🕉🙏
ALL
asif
asif
@aj_raja
THE LAST PRINCESS OF LAHORE - BAMBA DULEEP SINGH (1869 - 1957)

Thread

Post partition, every morning a weak old woman would board the Model Town bus service headed to the city. The conductor never asked her for money or he would invite anger of the last Queen of Punjab.

1/n


Princess Bamba Sutherland, the eldest daughter of Maharaja Duleep Singh and grand-daughter of Maharaja Ranjit Singh, was born on Sep 29, 1869, in London.

Duleep Singh, the last Maharaja of Punjab was taken away to England by British after annexing Punjab.

2/n


Since he was still a child he was forcibly converted to Christianity and made to adopt British values in order to prevent him from ever thinking about regaining Punjab.

He was also kept away from his mother Maharani Jindan.
When he finally met his mother years later...

3/n

...he was told about his lost kingdom and religion after which he decided to reclaim it from British treachery.
During his struggle he married and had six children, 3 sons & 3 daughters from the 1st marriage.

Bamba was the most colorful character among 6 and was a rebel...
4/n

...like her father and daring like her Grandfather Ranjit Singh. She married Col Sutherland who later became principal of King Edward Medical College.

When she got permission to bring her grandmother Maharani Jindan's ashes to Lahore in 1924, she saw a huge crowd gathered...
5/n
HISTORY
Priyanka (Astrology Guidance)
Priyanka (Astrology Gu...
@AstroAmigo
1

From today, we will memorize the names of 27 Nakshatras in Vedic Jyotish to never forget in life.

I will write 4 names. Repeat them in SAME sequence twice in morning, noon, evening. Each day, revise new names + recall all previously learnt names.

Pls RT if you are in.

2

Today's Nakshatras are:-

1. Ashwini - अश्विनी

2. Bharani - भरणी

3. Krittika - कृत्तिका

4. Rohini - रोहिणी

Ashwini - अश्विनी is the FIRST Nakshatra.

Repeat these names TWICE now, tomorrow morning, noon and evening. Like this tweet if you have revised 8 times as told.

3

Today's Nakshatras are:-

5. Mrigashira - मृगशिरा

6. Ardra - आर्द्रा

7. Punarvasu - पुनर्वसु

8. Pushya - पुष्य

First recall previously learnt Nakshatras twice. Then recite these TWICE now, tomorrow morning, noon & evening in SAME order. Like this tweet only after doing so.

4

Today's Nakshatras are:-

9. Ashlesha - अश्लेषा

10. Magha - मघा

11. Purvaphalguni - पूर्वाफाल्गुनी

12. Uttaraphalguni - उत्तराफाल्गुनी

Purva means that comes before (P se Purva, P se pehele), and Uttara comes later.

Read next tweet too.

5

Purva, Uttara prefixes come in other Nakshatras too. Purva= pehele wala. Remember.

First recall previously learnt 8 Nakshatras twice. Then recite those in Tweet #4 TWICE now, tomorrow morning, noon & evening in SAME order. Like this tweet if you have read Tweets #4 & 5, both.
VEDICNAKSHATRA