This will be my first and possibly last tweet (thread) as I am mostly here to learn. It is prompted by a recent study questioning lockdown efficacy that is getting a lot of attention. It appears people believe it to be the first of its kind, but I have been collecting similar
“there is no evidence that more restrictive nonpharmaceutical interventions (“lockdowns”) contributed substantially to bending the curve of new cases in England, France, Germany, Iran, Italy, the Netherlands, Spain, or the United States in early 2020”
“Inferences on effects of NPIs are non-robust and highly sensitive to model specification. Claimed benefits of lockdown appear grossly exaggerated.”
“government actions such as border closures, full lockdowns, and a high rate of COVID-19 testing were not associated with statistically significant reductions in the number of critical cases or overall mortality”
“Official data from Germany’s RKI agency suggest strongly that the spread of the coronavirus in Germany receded autonomously, before any interventions become effective”
“the decline in infections in England...began before full lockdown…[S]uch a scenario would be consistent with...Sweden, which began its decline in fatal infections shortly after the UK, but did so on the basis of measures well short of full lockdown”
“the UK lockdown was both superfluous (it did not prevent an otherwise explosive behavior of the spread of the coronavirus) and ineffective (it did not slow down the death growth rate visibly).”
“Given that the evidence reveals that the Corona disease declines even without a complete lockdown, it is recommendable to reverse the current policy and remove
the lockdown”
“stay at home orders, closure of all non-essential businesses and requiring the wearing of facemasks or coverings in public was not associated with any independent additional impact”
“these strategies might not have saved any life in western Europe. We also show that neighboring countries applying less restrictive social distancing measures … experience a very similar time evolution of the epidemic.”
“the model does not support [the] estimate that lockdown reduced the case reproduction number R by 81% or that more than three million deaths were averted by non-pharmaceutical interventions.”
“The case of Sweden, where the authors find the reduction in transmission to have been only moderately weaker than in other countries despite no lockdown having occurred, is prima facie evidence”
“general social distancing was also projected to reduce the number of cases but increase the total number of deaths compared with social distancing of over 70 only”
“Strategies that minimise deaths involve the infected fraction primarily being in the
“results presented in the report suggested that the addition of interventions restricting younger people
“We show that [lockdown] is modestly superior in saving lives compared to [focused protection], but with tremendous costs to prevent one case of death. This might result in overwhelming economic effects that are expected to increase future death toll”
“For pathogens that inflict greater morbidity at older ages, interventions that reduce but do not eliminate exposure can paradoxically increase the number of cases of severe disease by shifting the burden of infection toward older individuals”
“Current policy can be misdirected and can therefore have long and even short-term negative effects on human welfare and thus result in not actually minimizing death rates (incorporating externalities), especially in the long run.”
“For example, the data…shows a decrease in infection rates after countries eased...lockdowns with >99% statistical significance. Indeed...infection rates have declined after reopening even after allowing for an appropriate measurement lag.
“restrictions imposed by the pandemic (eg, stay-at-home orders) could claim lives indirectly through delayed care for acute emergencies, exacerbations of chronic diseases, and psychological distress (eg, drug overdoses).”
“In 14 states, more than 50%
“We found that 180-day of mandatory isolations to healthy <60 (ie schools and workplaces closed) produces more final deaths if the vaccination date is later than (Madrid: Feb 23 2021; Catalonia: Dec 28 2020; Paris: Jan 14 2021; London: Jan 22 2021)”
“Comparing weekly mortality in 24 European countries, the findings in this paper suggest that more severe lockdown policies have not been associated with lower mortality. In other words, the lockdowns have not worked as intended”
“Our findings … further raise doubt about the importance in NPI’s (lockdown policies in particular) in accounting for the evolution of COVID-19 transmission rates over time and across locations”
“[the] President...has flatly denied the seriousness of the pandemic, refusing to impose a lockdown, close schools, or cancel mass events…Yet the country’s death rate is among the lowest in Europe-just over 700 in a population of 9.5 million”
“living with children 0-11 years was not associated with increased risks of recorded SARS-CoV-2 infection, COVID-19 related hospital or ICU admission but was associated with reduced risk of COVID-19 death (HR 0.75, 95%CI 0.62-0.92).”
More from Category c19
1/: Avicenna was a Persian scientist, who lived 1000 years ago. He put two lambs in separate cages, which had the same health conditions. But only one lamb could see a wolf that was put in a third cage. The observations were astounding. (h/t @farmer_student) ⬇️a thread⬇️
2/: Both lambs were provided with the same feed. Also, the weight was exactly the same when the experiment started. Several months later, the lamb with sight on the wolf became cranky, restless, weak, and showed a significant weight loss and signs of poor development.
3/: The lamb that was under chronic stress as it was placed in a situation of constant apparent danger died eventually. 🐑🪦 In fact, the wolf did not pose a danger at all, but this was beyond the lamb's perception.
4/: This experiment showed that increased levels of the stress hormone cortisol have a bad impact on the metabolism of mammals. And 1000 years after this experiment, we are facing a similar situation again but with the difference that we are aware of the impact of stress.
5/: Currently, we are overwhelmed with medial and governmental propaganda with respect to a common cold virus (that might hypothetically be more lethal though) that doesn't do harm to the majority of the people. Extreme global measures are taken.
2/: Both lambs were provided with the same feed. Also, the weight was exactly the same when the experiment started. Several months later, the lamb with sight on the wolf became cranky, restless, weak, and showed a significant weight loss and signs of poor development.
3/: The lamb that was under chronic stress as it was placed in a situation of constant apparent danger died eventually. 🐑🪦 In fact, the wolf did not pose a danger at all, but this was beyond the lamb's perception.
4/: This experiment showed that increased levels of the stress hormone cortisol have a bad impact on the metabolism of mammals. And 1000 years after this experiment, we are facing a similar situation again but with the difference that we are aware of the impact of stress.
5/: Currently, we are overwhelmed with medial and governmental propaganda with respect to a common cold virus (that might hypothetically be more lethal though) that doesn't do harm to the majority of the people. Extreme global measures are taken.
Cortisol is known as the 'stress hormone' and is a silent killer. Cortisol levels are increased by:
— Dr. Simon \u30c4 (@goddeketal) February 17, 2021
\U0001f449\U0001f3fc Fear & anxiety
\U0001f449\U0001f3fc Constant stress
\U0001f449\U0001f3fc Social isolation
The media propagated fear and political measures are counterproductive. They shorten our lives. https://t.co/6BZ34pVBjw
1/: The Nuremberg Code is a set of research ethics principles for human experimentation created as a result of the Nuremberg trials at the end of the Second World War. In light of the current events, they are more actual than ever before. ⬇️an important thread⬇️
2/: These so-called ‘Doctors’ Trial’ focused on physicians who conducted #inhumane and #unethical human experiments in German concentration camps, in addition to those who were involved in over 3,500,000 sterilizations of German citizens. (the picture shows doctors/criminals)
3/: Ten points of the code were given in the section of the verdict entitled "Permissible Medical Experiments". They can be found in detail on the following website:
4/: Point #1 means that the person involved should have legal capacity to give consent; should be so situated as to be able to exercise free power of choice, without the intervention of any element of force, fraud, or deceit.
5/: Using an insufficiently-tested vaccine on humans is unethical. However, as long as people voluntarily consent to receive the vaccine, being informed about all risks, everything is OK. Doing this with force, however, is against the Nuremberg Code.
2/: These so-called ‘Doctors’ Trial’ focused on physicians who conducted #inhumane and #unethical human experiments in German concentration camps, in addition to those who were involved in over 3,500,000 sterilizations of German citizens. (the picture shows doctors/criminals)
3/: Ten points of the code were given in the section of the verdict entitled "Permissible Medical Experiments". They can be found in detail on the following website:
4/: Point #1 means that the person involved should have legal capacity to give consent; should be so situated as to be able to exercise free power of choice, without the intervention of any element of force, fraud, or deceit.
5/: Using an insufficiently-tested vaccine on humans is unethical. However, as long as people voluntarily consent to receive the vaccine, being informed about all risks, everything is OK. Doing this with force, however, is against the Nuremberg Code.
Important - share: Camera footage out of care homes (USA, corrected), provided by @RobertKennedyJr's team. You can clearly see: Collateral Damages, Army assisting, force, death.
— Bobby Rajesh Malhotra \u30c4 (@Bobby_Network) February 17, 2021
Worldwide phenomen, also in Germany:https://t.co/GV7gqiPl1u
21st Century Nuremberg Trials-material pic.twitter.com/wPekgPYHIR
Italian researchers: vaccines will not work against SARSCoV2 because this virus does not only replicate in human cells like other viruses, this one replicates through bacteria too. This is the fundamental reason why antibiotics work & vaccines will not:
Here is the Italian-EU scientific study indicating SARSCoV2 replicates in bacteria, not only human cells, and that is why antibiotics work and these vaccines will not:
"The preliminary results suggest that SARS-CoV-2 replicates in bacterial
2 of the 4 authors of the study work at the European Commission. Another works at an Italian medical research facility called Craniomed: https://t.co/EETSM3nb3T
You can find all of CRANIOMED's Carlo Brogna's published scientific research articles here, take a look:
Here is the Italian-EU scientific study indicating SARSCoV2 replicates in bacteria, not only human cells, and that is why antibiotics work and these vaccines will not:
"The preliminary results suggest that SARS-CoV-2 replicates in bacterial
2 of the 4 authors of the study work at the European Commission. Another works at an Italian medical research facility called Craniomed: https://t.co/EETSM3nb3T
You can find all of CRANIOMED's Carlo Brogna's published scientific research articles here, take a look:
1/: The inventor of the corona PCR-Test @c_drosten is one of the #protagonists of the current crisis. He is known for involving himself in contradictions. In 2014, he gave a legendary #interview to @wiwo (https://t.co/jzTRh5Suhc) that I will address in this ⬇️short thread⬇️.
2/: The interview is significant because @c_drosten made totally sane statements back then that follow the principle of common sense. Considering his involvement in the "genesis of the current pandemic", his assertions appear in an entirely different
3/: In 2014, for instance, washing the hands was sufficient against being infected by coronaviruses. Several years he demands measures that destroy national economies and social life worldwide.
4/: Young @c_drosten also severely criticized the fact that Saudi Arabia used the PCR method to detect potential infections. From his point of view, that specific method could lead to many irrelevant cases. Nowadays, his view shifted his opinion towards 'collective punishment'.
5/: Whereas he demands "testing, testing, testing" nowadays and spreads panic and fear via (social) media, he heavily condemned that behaviour of Saudi media in 2014. On top of that, he expressed his concern that medial panic could increase the number of lab tests significantly.
2/: The interview is significant because @c_drosten made totally sane statements back then that follow the principle of common sense. Considering his involvement in the "genesis of the current pandemic", his assertions appear in an entirely different
The genesis of a pandemic.
— Pace \U0001f642 (@theotherphilipp) February 25, 2021
The #Corona crisis began with a panopticon of absurd events, improbable coincidences and outright lies.
Time for a review of the impossibilities.
A thread \U0001f9f5 pic.twitter.com/PLbETVv2p8
3/: In 2014, for instance, washing the hands was sufficient against being infected by coronaviruses. Several years he demands measures that destroy national economies and social life worldwide.
4/: Young @c_drosten also severely criticized the fact that Saudi Arabia used the PCR method to detect potential infections. From his point of view, that specific method could lead to many irrelevant cases. Nowadays, his view shifted his opinion towards 'collective punishment'.
5/: Whereas he demands "testing, testing, testing" nowadays and spreads panic and fear via (social) media, he heavily condemned that behaviour of Saudi media in 2014. On top of that, he expressed his concern that medial panic could increase the number of lab tests significantly.
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"I really want to break into Product Management"
make products.
"If only someone would tell me how I can get a startup to notice me."
Make Products.
"I guess it's impossible and I'll never break into the industry."
MAKE PRODUCTS.
Courtesy of @edbrisson's wonderful thread on breaking into comics – https://t.co/TgNblNSCBj – here is why the same applies to Product Management, too.
There is no better way of learning the craft of product, or proving your potential to employers, than just doing it.
You do not need anybody's permission. We don't have diplomas, nor doctorates. We can barely agree on a single standard of what a Product Manager is supposed to do.
But – there is at least one blindingly obvious industry consensus – a Product Manager makes Products.
And they don't need to be kept at the exact right temperature, given endless resource, or carefully protected in order to do this.
They find their own way.
make products.
"If only someone would tell me how I can get a startup to notice me."
Make Products.
"I guess it's impossible and I'll never break into the industry."
MAKE PRODUCTS.
Courtesy of @edbrisson's wonderful thread on breaking into comics – https://t.co/TgNblNSCBj – here is why the same applies to Product Management, too.
"I really want to break into comics"
— Ed Brisson (@edbrisson) December 4, 2018
make comics.
"If only someone would tell me how I can get an editor to notice me."
Make Comics.
"I guess it's impossible and I'll never break into the industry."
MAKE COMICS.
There is no better way of learning the craft of product, or proving your potential to employers, than just doing it.
You do not need anybody's permission. We don't have diplomas, nor doctorates. We can barely agree on a single standard of what a Product Manager is supposed to do.
But – there is at least one blindingly obvious industry consensus – a Product Manager makes Products.
And they don't need to be kept at the exact right temperature, given endless resource, or carefully protected in order to do this.
They find their own way.
The entire discussion around Facebook’s disclosures of what happened in 2016 is very frustrating. No exec stopped any investigations, but there were a lot of heated discussions about what to publish and when.
In the spring and summer of 2016, as reported by the Times, activity we traced to GRU was reported to the FBI. This was the standard model of interaction companies used for nation-state attacks against likely US targeted.
In the Spring of 2017, after a deep dive into the Fake News phenomena, the security team wanted to publish an update that covered what we had learned. At this point, we didn’t have any advertising content or the big IRA cluster, but we did know about the GRU model.
This report when through dozens of edits as different equities were represented. I did not have any meetings with Sheryl on the paper, but I can’t speak to whether she was in the loop with my higher-ups.
In the end, the difficult question of attribution was settled by us pointing to the DNI report instead of saying Russia or GRU directly. In my pre-briefs with members of Congress, I made it clear that we believed this action was GRU.
The story doesn\u2019t say you were told not to... it says you did so without approval and they tried to obfuscate what you found. Is that true?
— Sarah Frier (@sarahfrier) November 15, 2018
In the spring and summer of 2016, as reported by the Times, activity we traced to GRU was reported to the FBI. This was the standard model of interaction companies used for nation-state attacks against likely US targeted.
In the Spring of 2017, after a deep dive into the Fake News phenomena, the security team wanted to publish an update that covered what we had learned. At this point, we didn’t have any advertising content or the big IRA cluster, but we did know about the GRU model.
This report when through dozens of edits as different equities were represented. I did not have any meetings with Sheryl on the paper, but I can’t speak to whether she was in the loop with my higher-ups.
In the end, the difficult question of attribution was settled by us pointing to the DNI report instead of saying Russia or GRU directly. In my pre-briefs with members of Congress, I made it clear that we believed this action was GRU.
BREAKING: @CommonsCMS @DamianCollins just released previously sealed #Six4Three @Facebook documents:
Some random interesting tidbits:
1) Zuck approves shutting down platform API access for Twitter's when Vine is released #competition
2) Facebook engineered ways to access user's call history w/o alerting users:
Team considered access to call history considered 'high PR risk' but 'growth team will charge ahead'. @Facebook created upgrade path to access data w/o subjecting users to Android permissions dialogue.
3) The above also confirms @kashhill and other's suspicion that call history was used to improve PYMK (People You May Know) suggestions and newsfeed rankings.
4) Docs also shed more light into @dseetharaman's story on @Facebook monitoring users' @Onavo VPN activity to determine what competitors to mimic or acquire in 2013.
https://t.co/PwiRIL3v9x
Some random interesting tidbits:
1) Zuck approves shutting down platform API access for Twitter's when Vine is released #competition
2) Facebook engineered ways to access user's call history w/o alerting users:
Team considered access to call history considered 'high PR risk' but 'growth team will charge ahead'. @Facebook created upgrade path to access data w/o subjecting users to Android permissions dialogue.
3) The above also confirms @kashhill and other's suspicion that call history was used to improve PYMK (People You May Know) suggestions and newsfeed rankings.
4) Docs also shed more light into @dseetharaman's story on @Facebook monitoring users' @Onavo VPN activity to determine what competitors to mimic or acquire in 2013.
https://t.co/PwiRIL3v9x