AVA6000 approved by MHRA. Superb news. First dosing 'around mid-year'; first data to come within 3-4 months after that.

A summary thread on the significance of AVA6000 - and #AVCT's pre CISION platform as a whole - to both the oncology industry and to AVCT itself. 1/10

I have been working on pandemic outbreaks for 15 years.

There is a misunderstanding of the difference between the response in much of the West, versus successful countries (including New Zealand and Australia).

Summarizing:

1.Reactive versus proactive and goal oriented.

1/-

2.Mitigation (slowing transmission) versus elimination (stopping transmission)

3.Gradually responding to increasing levels of infection by imposing greater restrictions which enables the infection rate to grow (red zone strategy), …

2/

versus starting with high restrictions to arrest transmission and relaxing restrictions only when the number of new cases is so low that contact tracing or localized short term action can stop community transmission (green zone strategy, including localized "fire fighting").

3/

4.Trying to keep economic activity and travel as open as possible but perpetuating the economic harm and imposing yoyo restrictions, versus making an initial sacrifice of economic activity and travel in order to benefit from the rapid restoration of normal economic activity.

4/

5.Focusing attention on few individuals resistant to social action because of shortsightedness or selfishness, versus recognizing the vast majority do the right thing if given clear guidance and support, which is what matters for success, as elimination is a robust strategy.

5/

1. Most people are aware of the fail doxes posted by Jamilla Moor on @Snakeeater36 and myself. I'm going to go into the details (in layman terms) of exactly how a specific group of duhnonymous idiots came up with these fail doxes & I'll prove that they're wrong.

2. @Snakeeater36 posted this screenshot on his TL. He had exposed the page source code on tweet which included an image. Anyone can do this in Chrome by opening a tweet, clicking on the image, then right click on any open space on the screen, select "inspect", then "network".

3. In fact I did the same by pulling up a different tweet and image. You'll see the IP highlighted in yellow and the region Dallas TX. It's not my IP. It belongs to Akamai which is identified. Why is that important.......

4. Well Akamai is a Content Delivery Network also known as a CDN. A CDN, is a geographically distributed network of proxy servers (make note of the term "proxy" servers) and their data centers. More later on why this is important relative to the fail doxes.

5. CDNs allow companies like Twitter to provide better performance in uploading content, like images, by distributing the service spatially relative to end users. Rather than pushing content directly (left), Twitter uses CDN networks (right) to push/pull images from end users.

Thread: This is a long thread about my wife's grand-father: Vinayak Apte.
Born, brought up & lived in Pune. Aptewada, Sadashiv Peth. Qualified as an engineer in 1920s or so. Married around same time.
I promise you this is worth reading, so settle down with your cup of tea....1/n

Around 1921, young Vinayak writes to Mahatma Gandhi expressing his desire to join Bapu & work for freedom struggle.
Bapu writes back saying sending money for the ticket (₹5) & get your backside up here (not exactly these words, but you know what I mean!).
Bapu adds a PS...2/n

"If you change your mind, please return the ₹5 by money order to Sabarmati Ashram" Typical Bapu, you might say! Careful with money.
Vinayak quits his job & decides to go to Sabarmati. Entire extended Apte clan is horrified. Joining that fakir? Giving up your job? Ostracised.

Vinayak goes to Sabarmati with young wife & 2-3 yr old daughter. Wifey not impressed at all, bcoz on arriving there they are assigned to separate living quarters (men & women), celibacy & every1 (incl her, a Brahmin woman) was expected to clean toilets! Horror of horrors..3/n

Wife never forgave Vinayak & Bapu. She had married a engineer & was looking forward to a prosperous life. Life on other hand, was full of austerity. Everyone had to work & was paid a pittance. 5 am wake up.Cook. Clean. Khadi sarees (which btw weigh a ton!) & evening prayers...4/n

As a mom of 4 I have spent a significant amount of my time discussing the virtues of truth telling and the consequences of telling a lie, at this moment one of the kids is writing me an essay on using self-control to ensure her words are true.

On Monday @TuckerCarlson said, “The Green New Deal has come, believe it or not, to the state of Texas. How’s it working out so far?”

First GND is a resolution, second it hasn’t even been past, 3rd, we’re talking about TX. This is objectively false.

He went on to say, “Not a single major American city is prettier or more functional than it was in 1950. The parks that previous generations so lovingly built are filled with vagrants and junkies."

"The monuments they constructed are covered with spray paint. Public transportation is a disgrace. It’s filthy, the streets are dangerous. Are you really surprised that Cory Booker was once the mayor of Newark, New Jersey? You shouldn’t be.”

Wow, that’s a lot to unpack and has little to do with the lack of power in TX. For myself I believe the best is yet to come. I see the dog whistles there, and it’s an excellent example of racist demagoguery and a sure path towards the destruction of our democracy.