https://t.co/a6yrWK5dqg

An "Aquarium" needs cleaning in my opinion, but who am I, a mere monkey, to give advice?
Astonished at what @bellingcat discovered about GRU & FSB operations
Skripal https://t.co/PzH3a7JZvy
Navalny https://t.co/eZi63UhWw1
FSB https://t.co/sViYk9RwmB
GRU https://t.co/MY5d5gw2OG

A great post by Ilya Yahin on

Every time Putin talks about “our special services,” his signature smirk appears on his face, and in his words there is poorly concealed bragging
"Of course, we knew everything in advance"
"Yes, we are looking"
"Mercader has already been sent"
“World-class professionals”

Putin clearly loves all these spy games. He is very proud of the special services and therefore endlessly increases budget funding for them.
This is his top priority.
The elderly dictator cannot understand one thing:

there are no effective special services in a state that is completely corroded by corruption. You won't have honest professionals at your fingertips if your son-in-law buys shares of a state company for $ 100, the real value of which exceeds $ 380 million.

1/9 Thread on the Wuhan "seafood market" Environmental Samples Issue
Conspiracy theories and doubt proliferate when there is lack of transparency. For example, regarding environmental samples which tested positive at the Wuhan seafood market

10. Conclusion:
CCDC has refused to release this data, has refused to release specific detail of environmental samples tested positive at market, refused permission for WHO to investigate & has stonewalled all attempts to obtain key information.
Why do you think CCDC does this?

With @franklowery our new study on attributes of T cells that contribute to successful cell therapy in cancer patients in @ScienceMagazine today w/ colleagues @slgoff_SB, @NCI_CCR_SB @theNCI a TL;DR thread on key findings with caveats :) 1/10

has a long history of using tumor infiltrating T cells (TILs) to treat cancers since well.. before I was even born. We analyzed our most successful melanoma ACT trial for cell surface phenotypes in TIL infusion products of patients (aPD1/immunotherapy naive) /2

Surprisingly we found a CD39- TIL subset (CD39-CD69-, DN) associated with ACT-response. TBH we were expecting the opposite (CD39+). We only included CD39 bcz multiple groups (e.g. Simoni et al, 2018) had reported CD39+ as enriching for anti-tumor/neoantigen reactive T cells. /3

CD39- DN TILs RNA/epigenetics resemble stem-like memory progenitors, and in vitro were able to self-renew, and give rise to other CD39+ subsets. OTOH the most dominant subset of patient infusion products were CD39+ CD69+ (DP) and these guys were terminally differentiated.. /4

So, to clarify we specifically analyzed tumor-specific mutation-reactive Tcells. Turns out, ACT-responders had pool of neoantigen-reactive TILs in the CD39- phenotype, while non-responders did not (despite other irrelevant CD39- Tcells) -> not all CD39- T cells are bystanders /5

So proud of my @UNGlobalPulse team and collaborators that step by step and over the years have managed to bring 🤖 science closer to humanitarian and development work. We now have a library!! 📚 📚📚 https://t.co/rOxXQRllo5 Some peer-reviewed highlights in this thread 👇

Let's talk about Avi Loeb and his theory about alien

First, I should disclose that I work at the fame research facility as Dr. Loeb, though I work in a different department and to my recollection we've never met.

He's a scientist; I'm in computer support.

With that out of the way...
The interview above is worth a read, and a lot of serious thought, because there's an idea there that's really critical to science, and it isn't whether or not aliens have visited (exactly).

It's about how fashion and culture and taboo have an unfortunately strong effect on science.

In particular he compares his theory on alien visitation with the multiverse theory.

Which of these is more deserving of ridicule?

Science is fundamentally a structure for forming hypotheses and then (critically) testing these hypotheses to see if they should be kept, rejected, or modified.

Wonder why your Ph.D./Master's application is being rejected?

Here are some insider reasons (from a committee member) that result in such "Love Letters" 👇

- A Short Thread

1) First, you should know that sometimes, an independent reviewer is required (especially in the US) to review applications even after PIs must have selected their candidates. So, even if any bias slips through the PI, the independent reviewer will pick it up.

2) Having said this, there are three major issues that application reviewers/committees often find with your application. These three components make your applications almost challenging to assess.

3) NUMBER ONE - Incomplete Applications

This occurs when you do not upload the requested documents needed to evaluate your file. Think of a candidate that did not send a GRE score when the institution clearly requires it for admission.

4) NUMBER TWO - Error laden Essays

This is particularly interesting because based on reports from this resource person, it is not particularly about how little your experience is but how you communicate it error-free or at least extensively minimized. This gives headache!