BC SCIENCE
Saved by @jacobhtml

1. I find it remarkable that some medics and scientists aren’t raising their voices to make children as safe as possible. The comment about children being less infectious than adults is unsupported by evidence.

 2. @c_drosten has talked about this extensively and @dgurdasani1 and @DrZoeHyde have repeatedly pointed out flaws in the studies which have purported to show this. Now for the other assertion: children are very rarely ill with COVID19.
3. Children seem to suffer less with acute illness, but we have no idea of the long-term impact of infection. We do know #LongCovid affects some children. @LongCovidKids now speaks for 1,500 children struggling with a wide range of long-term symptoms.
4. 1,500 children whose parents found a small campaign group. How many more are out there? We don’t know. ONS data suggests there might be many, but the issue hasn’t been studied sufficiently well or long enough for a definitive answer.
5. Some people have talked about #COVID19 being this generation’s Polio. According to US CDC, Polio resulted in inapparent infection in more than 99% of people. Severe disease occurred in a tiny fraction of those infected. Source: https://t.co/Wpfrk9qsHJ
6. In the US, the peak of severe disease came in 1952 when over 20,000 people in the US suffered paralysis. As this fascinating case report shows, mild illness as a child could be followed by severe complications many years later.

https://t.co/psnsLaHAZM
7. Did people focus only on the 99% who survived the disease? Did people seek to minimise the experiences and suffering of the unlucky few? No. The world came together to eradicate the disease. I’m not suggesting #COVID19 is as serious as Polio.
8. But I am saying there are many unanswered questions. Polio didn’t burst onto the scene. It took decades for the disease to reach its peak & for scientists to properly understand it. We’ve been living with COVID19 for less than a year. It seems cavalier to dismiss risk.
9. It also shows a lack of empathy to sideline parents who are struggling to understand what’s happening to their children. Until there is good data on prevalence of #LongCovid in children and evidence that explains the mechanisms of the condition, risk cannot be quantified.
10. And I say mechanisms because possible explanations for #LongCovid could be organ damage, neuro invasion, viral persistence, or the development of autoantibodies. Until we understand the condition better, I’m not sure why we’d celebrate ignorance.
11. Does this mean we have to hibernate until science catches up? No. But it would seem prudent to minimise risk whenever possible. The UK is almost alone in not mandating masks in classrooms. It has not implemented many of the aerosol mitigation measures seen around the world.
12. We’re not taking reasonable steps to protect children. Steps that would also benefit the community at large by slowing transmission. If we’ve learned anything from the past year it’s that precaution is the better approach.
13. For some reason the issue of child safety has become politicised, with fringe groups arguing against safety measures adopted in almost every other developed country. If we want our schools to stay open, we need to make an effort to make them safe.
14. Reduce risk as much as reasonably possible while science catches up on a new disease and medicine vaccinates or treats the problem into irrelevance.

More from Adam Hamdy

Adam Hamdy
Adam Hamdy
@adamhamdy
1. I believe the government is about to make another huge mistake. Where is @UKLabour in all this? I have some questions @Keir_Starmer should be asking urgently. Please RT to raise awareness.


2. Where is the modelling or evidence to support a focused protection vaccination strategy? The government has chosen it as its preferred strategy but it must have considered other options. Will the government publish the data and the alternative options considered?

3. A responsible government will have modelling for 20%, 50% and 80% vaccine coverage, and projections for the number of infections, Long Covid and deaths in each scenario. Where are those models? On what basis has the government opted for the 20% scenario?

4. The government should also have modelled each of these scenarios against a backdrop of low, medium and high community transmission. What is the impact of each vaccination scenario against varying levels of community transmission?

5. There should also be some assessment of incidence of reinfection and likely evolution of variants given different levels of community transmission. What does this assessment tell us?
GOVERNMENT
Adam Hamdy
Adam Hamdy
@adamhamdy
1. The problem facing Europe & the US isn't a scientific one. Scientists have been clear for months: public health and economic & social wellbeing are best served by policies that supress the virus. The #JohnSnowMemo cites evidence that makes this

2. Some media commentators seek to present the issue of how to respond to the virus in simplistic terms: Lockdown vs Herd Immunity. This a mischaracterisation. The countries that have tackled #COVID-19 best have used a range of public health


3. Almost every scientist acknowledges lockdown equals failure. It is a sign governments have failed to implement the measures needed to allow life to be lived more or less as normal, without risking exponential growth in transmission.

4. There is an active misinformation campaign that is being aided and abetted by certain sections of the media and some politicians. The campaign would have us believe that if we open up and shield the vulnerable, all will be well. This approach has been derided as inhumane...

5. ...by the WHO, and ridiculous by Dr Fauci for many reasons. It is based on faulty logic, and the proponents of this approach have submitted no evidence that it can be achieved nor any practical examples of how they would do so.
SOCIETY
Advertisement
Adam Hamdy
Adam Hamdy
@adamhamdy
1. THE PLAN

We see countries like China & New Zealand succeed by implementing border controls and wonder why our government didn’t do the same. Unfortunately, it’s been following the 2011 influenza pandemic plan, which says...


2. China & New Zealand have international travel (limited in the case of New Zealand) and freight, and rather than delay their peaks, their border controls have helped keep cases to a minimum. Border controls might not work in a flu pandemic, but they worked for #COVID19.

3. Countries that have done well against #COVID19 have high adherence to mask wearing. The pandemic plan tells us the British people won’t bother wearing masks over time so let’s no bother asking them to, eh.


4. Mass super spreading events have been shown to play a significant role in the transmission of #COVID19.

But the pandemic plan tells us they don’t play a role (perhaps the source of Jenny Harries’ comments about Cheltenham?) and therefore the government will not restrict them


5. I call this the white flag clause. Surrender was built into the assumptions behind our pandemic response. The success of other countries has proved this clause completely wrong.
TRAVEL
Adam Hamdy
Adam Hamdy
@adamhamdy
1. Last NYE was a quiet one for @AmyMcLellan2 & I, after a busy year writing and helping @DavidHHeadley and @LizzieCurle organise @CapitalCrime1

Someone I follow on Twitter shared this story, and we jokingly said we hoped it wouldn’t be another SARS.

2. A few days later, after watching social media footage coming out of Wuhan, I went for a meeting to plan Capital Crime 2021, and said it was likely we’d have to cancel the festival because of the emerging pandemic. My partners in crime looked at me as though I was unhinged.

3. As the situation worsened, I reconnected with people I knew from my previous life working as a consultant to the medical industry, and it became clear we were witnessing the start of a pandemic.

4. Knowing something about the history of pandemics, I was aware that early intervention, and quick and decisive action were essential. I was asked to write a report for Matt Hancock on the risks of reinfection and long-term ill health caused by coronaviruses.

5. Knowing the public health and economic costs of a pandemic, I joined people like @DrEricDing trying to raise the alarm in February, calling for decisive government action. In the report sent to Hancock, I recommended a 4-week precautionary border closure and lockdown...
HEALTH
Adam Hamdy
Adam Hamdy
@adamhamdy
1. This thread has been given a new lease of life today. People keep saying, "We can't do #ZeroCovid, it doesn't fit with our way of life."

Look around.

What way of life?

The one we used to have?

The UK has been under varying degrees of restriction since March 23rd 2020.


2. Nearly a year of having our social and economic freedoms curtailed in one way or another. Nearly a year of muted economic activity. Nearly a year of mass death and disease.

#ZeroCovid doesn't fit with a way of life that doesn't exist anymore.

3. The question isn't whether it fits with our old freewheeling ways, but whether it would lead to better outcomes than the UK's current (poorly defined) strategy? Experiences in New Zealand, Australia, Vietnam, China, Taiwan and elsewhere very much suggest it would.

4. #ZeroCovid isn't about what's possible. It's about what's necessary. Decide what's necessary and figure out a way to make it possible. We can't force travellers to quarantine in hotels for two weeks? Why not? Taiwan does. And if that's what's necessary, why aren't we doing it?

5. I've heard some odd things said about #ZeroCovid

Simple-minded clod Matt Hancock said Zero Covid is impossible because no country has had zero cases.

Zero Covid sets out an ambition. It signals a country treats any infections as serious
SOCIETY

More from Science

Prof. Gavin Yamey MD MPH
Prof. Gavin Yamey MD M...
@GYamey
I want to share my thoughts, as someone who has been so alarmed by the so-called "dissident" scientists like Gupta, Heneghan, Kuldorff, Bhattacharya, & Ioannidis who consider themselves brave Galileos unfairly treated by "establishment scientists." I will try not to swear. 1/n


I want to talk about 3 things:
‼️Their fringe views are inhumane, unethical junk science that promotes harm
‼️They complain that they've been marginalized but this is simply untrue
‼️I am sick of people telling me we have to "listen to both sides." There aren't 2 sides here 2/n

These 'dissident' scientists have consistently downplayed COVID-19, urging policymakers not to take aggressive control measures. They claim it is not a serious threat. Gupta even went on TV saying people under 65 shouldn't worry about it!

RECEIPTS

They have consistently argued that policymakers should just let the virus rip, in an attempt to reach herd immunity by natural infection. Kuldorff *continues* to argue for this even now that we have many highly effective, safe vaccines.


We've never controlled a deadly, contagious pandemic before by just letting the virus spread, as this approach kills & disables too many people. In Manaus, Brazil, 66% of the city was infected & an astonishing *1 in 500* people died of COVID-19
SCIENCE
10-K Diver
10-K Diver
@10kdiver
1/

Get a cup of coffee.

In this thread, I'll help you understand the basics of Binomial Thinking.

The future is always uncertain. There are many different ways it can unfold -- some more likely than others. Binomial thinking helps us embrace this view.


2/

The S&P 500 index is at ~3768 today.

Suppose we want to predict where it will be 10 years from now.

Historically, we know that this index has returned ~10% per year.

If we simply extrapolate this, we get an estimate of ~9773 for the index 10 years from now:


3/

What we just did is called a "point estimate" -- a prediction about the future that's a single number (9773).

But of course, we know the future is uncertain. It's impossible to predict it so precisely.

So, there's a sense of *false precision* in point estimates like this.

4/

To emphasize the uncertainty inherent in such predictions, a better approach is to predict a *range* of values rather than a single number.

For example, we may say the index will return somewhere in the *range* of 8% to 12% (instead of a fixed 10%) per year.

5/

10 years from now, this implies an index value in the *range* [8135, 11703]:
SCIENCE
Advertisement
10-K Diver
10-K Diver
@10kdiver
1/

Get a cup of coffee.

In this thread, we'll cover *State Quantities* and *Flow Quantities*.

This mental model can help us analyze many different entities -- from complex engineering systems to publicly traded companies.


2/

A "State Quantity" is something that's associated with a *specific point in time*.

For example, the number of followers a Twitter account has is a state quantity. This number can go up and down over time. But at any one *specific* time point, it's fixed.

3/

Similarly, the amount of cash a company has is a state quantity.

This cash balance can also rise and fall over time.

But pick any one *specific* time point -- and the company can only have one *specific* cash balance at that time point.

4/

By contrast, a "Flow Quantity" is something that's associated with a time *interval* rather than a time *point*.

For example, the number of followers gained by a Twitter account is a flow quantity. It's meaningful only when we specify a time interval (eg, the last 30 days).

5/

A simple analogy is that a State Quantity is like a photo -- a snapshot at a particular *point* in time.

But a Flow Quantity is like a video -- a record of events that take place during a particular time *interval*.
SCIENCE , FINANCE
Rebecca \U0001f983 "Stay the Fuck Home" \U0001f983 Watson
Rebecca 🦃 "Stay the Fu...
@rebeccawatson
So it turns out that an organization I thought was doing good work, the False Memory Syndrome Foundation (associated with Center for Inquiry, James Randi, and Martin Gardner) was actually caping for pedophiles. Uhhhh oops?


Since this, bizarrely, turned out to be one of my longest videos ever (??) here's a quick thread to sum it up for those of you like myself with short attention spans. 1/10

In the '90s the False Memory Syndrome Foundation was founded to call attention to the problem of adults suddenly "remembering" child abuse that never actually happened, often under hypnosis. Skeptics like James Randi & Martin Gardner joined their board. 2/10

A new article reveals that the FMSF was founded by parents who had been credibly and PRIVATELY accused of molestation by their now-adult daughter. They publicized the accusation, destroyed the daughter's reputation, and started the foundation. 3/10

The FMSF assumed any accused pedo who joined was innocent, saying "We are a good-looking bunch of people, graying hair, well dressed, healthy, smiling; just about every person who has attended is someone you would surely find interesting and want to count as a friend" 😬 4/10
SCIENCE
Judy Melinek M.D.
Judy Melinek M.D.
@drjudymelinek
Cognitive Bias in Forensic Pathology Decisions was published today by Journal of Forensic Sciences

From the abstract “We examined all death certificates issued during a 10-year period in the State of Nevada in the United States for children under the age of six.” /2

We also conducted an experiment with 133 forensic pathologists in which we tested whether knowledge of irrelevant non-medical information that should have no bearing on fo- rensic pathologists’ decisions influenced their manner of death determinations. /3

The dataset of death certificates indicated that forensic pathologists were more likely to rule "homicide" rather than "accident" for deaths of Black children relative to White children. /4

“Participants read a vignette describing a not straightforward or simple case in which a 3.5-year-old child was presented to an ED with diminished vital signs and who died shortly after arrival. /5
SCIENCE

You May Also Like

The Chartians
The Chartians
@chartians
Took me 5 years to get the best Chartink scanners for Stock Market, but you’ll get it in 5 mminutes here ⏰

Do Share the above tweet 👆

These are going to be very simple yet effective pure price action based scanners, no fancy indicators nothing - hope you liked it.

https://t.co/JU0MJIbpRV

52 Week High
One of the classic scanners very you will get strong stocks to Bet on.

https://t.co/V69th0jwBr

Hourly Breakout
This scanner will give you short term bet breakouts like hourly or 2Hr breakout

Volume shocker
Volume spurt in a stock with massive X times
SCREENERS , ALL , CHARTLINK SCREENERS
Jaya_Upadhyaya
Jaya_Upadhyaya
@Jayalko1
SRI KUMARIAMMAN, KANYAKUMARI (TN)
#bharatmandir #navratri2021

Created by Maharshi Parasurama and also one among the 108 Shakthi Peethas in the world. The name Kanyakumari stands for Kanya(Virgin) and Kumari(girl).
Devi took this form to vanquish the demon Banasura
@GunduHuDuGa


Once, Banasura(grand son of Mahabali) obtained a boon from Shiva that he could be vanquished only by a virgin.
So, Devi took the form of a kumari and started meditating with the desire to marry Shiva at Suchindram.
Pleased Shiva fixed the midnight hour for marriage with Devi.


Devarshi Narada knew that the marriage would end the chance of killing Banasura. So, he assumed the form of a cock and crowed. Shiva returned back to Suchindram thinking that it was dawn.
Angered, Devi cursed that all food and articles meant for wedding turn into sand and shells


When Banasura heard about Devi’s beauty, he tried to take her by force. Devi, then, killed him and granted the wish of Devas to remain there always protecting them.
The murti of Devi stands with a rosary in hand. Her diamond nose-ring is said to be visible even from the sea.


Once an ancient mariner mistook it for a lighthouse and sailing towards it, his ship wrecked upon the Kanya Kumari rocks. In order to prevent such a tragedy from happening again, the eastern door of the shrine is opened only on five special occasions throughout the year.
ALL
Advertisement
Erik Torenberg
Erik Torenberg
@eriktorenberg
1/ Someone emailed me asking how to break into VC, so I wanted to answer on Twitter where others could see and contribute to the conversation.

2/ “Being a VC” can mean a lot of different things, so it’s worth asking:

What actual activities do you want to do?

- Deep market analysis?
- Be in the flow of information and people?
- Make deals?
- Work closely w/ founders over time (e.g take board seats?)
- Manage capital?

3/ It’s worth specifying what type of VC you might like to become — as there are different archetypes. E.g.

- Benchmark (Lead series A/B - couple investments a year)
- First Round (Lead seed rounds, partner w/ a few companies a year)
- SV Angel (Make lots of seed investments)

4/ Continued:

Expa - Incubate companies

YC / Village Global - Build a platform to help entrepreneurs at scale

Do you want to join a firm or start one? There’s a lot to consider.

Different paths will require different skillsets & sets of experiences.

5/ Since the person who wrote the email is a young person trying to break into VC by joining a firm (and who doesn’t want to start a company), I’ll tailor this tweet storm to that goal. There’s some overlap.
STARTUPS
Vibhu Vashisth
Vibhu Vashisth
@VIBHU_Tweet
Did you know?

When Saudi Arabia's King visited India in 1955, PM Nehru ordered all the Hindu Temples and Idols of Hindu Deities that came in Saudi King's way to be covered up.
Our temples are the architectural marvels in their own league.


Each of our temples tells the story of our rich history and cultural heritage. Was Nehru that ashamed of his own nation's heritage that he had to cover them up or there was some other reason? The answer would be best known to him only.

PM Nehru invited the then Saudi King Saud bin Abdul Aziz to India who accepted the invitation and planned a 17 day long official visit to India in 1955. Saudi King had brought a large delegation with him and he had to visit various Indian cities like Mumbai, Hyderabad, Agra,


Aligarh, Shimla, Mysore and Varanasi. However, when Saudi King reached Varanasi, Nehru ordered to cover all the temples and Idols with curtains that came in the way of the Royal Convoy. During his stay in Varanasi, Govt buildings were painted with the words "Kalma Tayyiba".


'Kalma Tayyiba' means 'There is not God but only Allah and Mohammed is his messenger'. In addition to it, Pooja and Aartis were also stopped at temples. I can call it the appeasement politics of the highest order and Nehru was indeed the greatest appeaser of all times.
ALL
Robin Berjon
Robin Berjon
@robinberjon
Recently, the @CNIL issued a decision regarding the GDPR compliance of an unknown French adtech company named "Vectaury". It may seem like small fry, but the decision has potential wide-ranging impacts for Google, the IAB framework, and today's adtech. It's thread time! 👇

It's all in French, but if you're up for it you can read:
• Their blog post (lacks the most interesting details): https://t.co/PHkDcOT1hy
• Their high-level legal decision: https://t.co/hwpiEvjodt
• The full notification: https://t.co/QQB7rfynha

I've read it so you needn't!

Vectaury was collecting geolocation data in order to create profiles (eg. people who often go to this or that type of shop) so as to power ad targeting. They operate through embedded SDKs and ad bidding, making them invisible to users.

The @CNIL notes that profiling based off of geolocation presents particular risks since it reveals people's movements and habits. As risky, the processing requires consent — this will be the heart of their assessment.

Interesting point: they justify the decision in part because of how many people COULD be targeted in this way (rather than how many have — though they note that too). Because it's on a phone, and many have phones, it is considered large-scale processing no matter what.
TECH