BC SCIENCE
Saved by @jacobhtml

1. I find it remarkable that some medics and scientists aren’t raising their voices to make children as safe as possible. The comment about children being less infectious than adults is unsupported by evidence.

 2. @c_drosten has talked about this extensively and @dgurdasani1 and @DrZoeHyde have repeatedly pointed out flaws in the studies which have purported to show this. Now for the other assertion: children are very rarely ill with COVID19.
3. Children seem to suffer less with acute illness, but we have no idea of the long-term impact of infection. We do know #LongCovid affects some children. @LongCovidKids now speaks for 1,500 children struggling with a wide range of long-term symptoms.
4. 1,500 children whose parents found a small campaign group. How many more are out there? We don’t know. ONS data suggests there might be many, but the issue hasn’t been studied sufficiently well or long enough for a definitive answer.
5. Some people have talked about #COVID19 being this generation’s Polio. According to US CDC, Polio resulted in inapparent infection in more than 99% of people. Severe disease occurred in a tiny fraction of those infected. Source: https://t.co/Wpfrk9qsHJ
6. In the US, the peak of severe disease came in 1952 when over 20,000 people in the US suffered paralysis. As this fascinating case report shows, mild illness as a child could be followed by severe complications many years later.

https://t.co/psnsLaHAZM
7. Did people focus only on the 99% who survived the disease? Did people seek to minimise the experiences and suffering of the unlucky few? No. The world came together to eradicate the disease. I’m not suggesting #COVID19 is as serious as Polio.
8. But I am saying there are many unanswered questions. Polio didn’t burst onto the scene. It took decades for the disease to reach its peak & for scientists to properly understand it. We’ve been living with COVID19 for less than a year. It seems cavalier to dismiss risk.
9. It also shows a lack of empathy to sideline parents who are struggling to understand what’s happening to their children. Until there is good data on prevalence of #LongCovid in children and evidence that explains the mechanisms of the condition, risk cannot be quantified.
10. And I say mechanisms because possible explanations for #LongCovid could be organ damage, neuro invasion, viral persistence, or the development of autoantibodies. Until we understand the condition better, I’m not sure why we’d celebrate ignorance.
11. Does this mean we have to hibernate until science catches up? No. But it would seem prudent to minimise risk whenever possible. The UK is almost alone in not mandating masks in classrooms. It has not implemented many of the aerosol mitigation measures seen around the world.
12. We’re not taking reasonable steps to protect children. Steps that would also benefit the community at large by slowing transmission. If we’ve learned anything from the past year it’s that precaution is the better approach.
13. For some reason the issue of child safety has become politicised, with fringe groups arguing against safety measures adopted in almost every other developed country. If we want our schools to stay open, we need to make an effort to make them safe.
14. Reduce risk as much as reasonably possible while science catches up on a new disease and medicine vaccinates or treats the problem into irrelevance.

More from Adam Hamdy

Adam Hamdy
Adam Hamdy
@adamhamdy
1. The problem facing Europe & the US isn't a scientific one. Scientists have been clear for months: public health and economic & social wellbeing are best served by policies that supress the virus. The #JohnSnowMemo cites evidence that makes this

2. Some media commentators seek to present the issue of how to respond to the virus in simplistic terms: Lockdown vs Herd Immunity. This a mischaracterisation. The countries that have tackled #COVID-19 best have used a range of public health


3. Almost every scientist acknowledges lockdown equals failure. It is a sign governments have failed to implement the measures needed to allow life to be lived more or less as normal, without risking exponential growth in transmission.

4. There is an active misinformation campaign that is being aided and abetted by certain sections of the media and some politicians. The campaign would have us believe that if we open up and shield the vulnerable, all will be well. This approach has been derided as inhumane...

5. ...by the WHO, and ridiculous by Dr Fauci for many reasons. It is based on faulty logic, and the proponents of this approach have submitted no evidence that it can be achieved nor any practical examples of how they would do so.
SOCIETY
Adam Hamdy
Adam Hamdy
@adamhamdy
1. I believe the government is about to make another huge mistake. Where is @UKLabour in all this? I have some questions @Keir_Starmer should be asking urgently. Please RT to raise awareness.


2. Where is the modelling or evidence to support a focused protection vaccination strategy? The government has chosen it as its preferred strategy but it must have considered other options. Will the government publish the data and the alternative options considered?

3. A responsible government will have modelling for 20%, 50% and 80% vaccine coverage, and projections for the number of infections, Long Covid and deaths in each scenario. Where are those models? On what basis has the government opted for the 20% scenario?

4. The government should also have modelled each of these scenarios against a backdrop of low, medium and high community transmission. What is the impact of each vaccination scenario against varying levels of community transmission?

5. There should also be some assessment of incidence of reinfection and likely evolution of variants given different levels of community transmission. What does this assessment tell us?
GOVERNMENT
Advertisement
Adam Hamdy
Adam Hamdy
@adamhamdy
1. This thread has been given a new lease of life today. People keep saying, "We can't do #ZeroCovid, it doesn't fit with our way of life."

Look around.

What way of life?

The one we used to have?

The UK has been under varying degrees of restriction since March 23rd 2020.


2. Nearly a year of having our social and economic freedoms curtailed in one way or another. Nearly a year of muted economic activity. Nearly a year of mass death and disease.

#ZeroCovid doesn't fit with a way of life that doesn't exist anymore.

3. The question isn't whether it fits with our old freewheeling ways, but whether it would lead to better outcomes than the UK's current (poorly defined) strategy? Experiences in New Zealand, Australia, Vietnam, China, Taiwan and elsewhere very much suggest it would.

4. #ZeroCovid isn't about what's possible. It's about what's necessary. Decide what's necessary and figure out a way to make it possible. We can't force travellers to quarantine in hotels for two weeks? Why not? Taiwan does. And if that's what's necessary, why aren't we doing it?

5. I've heard some odd things said about #ZeroCovid

Simple-minded clod Matt Hancock said Zero Covid is impossible because no country has had zero cases.

Zero Covid sets out an ambition. It signals a country treats any infections as serious
SOCIETY
Adam Hamdy
Adam Hamdy
@adamhamdy
1. THE PLAN

We see countries like China & New Zealand succeed by implementing border controls and wonder why our government didn’t do the same. Unfortunately, it’s been following the 2011 influenza pandemic plan, which says...


2. China & New Zealand have international travel (limited in the case of New Zealand) and freight, and rather than delay their peaks, their border controls have helped keep cases to a minimum. Border controls might not work in a flu pandemic, but they worked for #COVID19.

3. Countries that have done well against #COVID19 have high adherence to mask wearing. The pandemic plan tells us the British people won’t bother wearing masks over time so let’s no bother asking them to, eh.


4. Mass super spreading events have been shown to play a significant role in the transmission of #COVID19.

But the pandemic plan tells us they don’t play a role (perhaps the source of Jenny Harries’ comments about Cheltenham?) and therefore the government will not restrict them


5. I call this the white flag clause. Surrender was built into the assumptions behind our pandemic response. The success of other countries has proved this clause completely wrong.
TRAVEL
Adam Hamdy
Adam Hamdy
@adamhamdy
1. Last NYE was a quiet one for @AmyMcLellan2 & I, after a busy year writing and helping @DavidHHeadley and @LizzieCurle organise @CapitalCrime1

Someone I follow on Twitter shared this story, and we jokingly said we hoped it wouldn’t be another SARS.

2. A few days later, after watching social media footage coming out of Wuhan, I went for a meeting to plan Capital Crime 2021, and said it was likely we’d have to cancel the festival because of the emerging pandemic. My partners in crime looked at me as though I was unhinged.

3. As the situation worsened, I reconnected with people I knew from my previous life working as a consultant to the medical industry, and it became clear we were witnessing the start of a pandemic.

4. Knowing something about the history of pandemics, I was aware that early intervention, and quick and decisive action were essential. I was asked to write a report for Matt Hancock on the risks of reinfection and long-term ill health caused by coronaviruses.

5. Knowing the public health and economic costs of a pandemic, I joined people like @DrEricDing trying to raise the alarm in February, calling for decisive government action. In the report sent to Hancock, I recommended a 4-week precautionary border closure and lockdown...
HEALTH

More from Science

Smit Patel
Smit Patel
@snazzysmit
Super excited to share my very first lead-author paper in @ScienceAdvances

Supported by @HIRN_CC @NIDDKgov @UFBME @UFWertheim @ufdiabetes @UMCoEDean
Lead by @Cherie_Stabler & @ashu83

link: https://t.co/FbqVWQ0n5p

This is a thread 👇

Highlights:
⚪️A Lab-on-a-Chip platform for organoids w/ wide capabilities: long-term culture | controlled & dynamic perifusion | in situ spatio-temporal imaging | serial cell assessment | ease of sample retrieval


⚪️Continuous fluidic flow increased local oxygen supply to islets in hydrogels & reduced cellular hypoxia
⚪️Flow increased cellular viability & reduced apoptosis & cell death

⚪️Human islets in hydrogels were highly functional during the 10 day in situ culture in our chips, while islet function was rapidly lost under static conditions
⚪️Glucolipotoxicity study showed a treatment window as small as 2.5 hours can elevate cell death

What are organoids? – A miniaturized version of an organ that imitate an aspect of human interface. They are commonly developed from stem cells in a lab. Human body also produces organoids naturally particularly within the pancreas.
SCIENCE
Dr Naomi Wolf
Dr Naomi Wolf
@naomirwolf
1/Just had an interview scheduled with @goddeketal, Dr Simon Goddek, the post-doctoral researcher at the Faculty of Mathematics and Statistics in the field of biotechnology, at an unnamed Dutch university. This researcher has been publicly pointing out that the paper that...

2/ the PCR test as the gold standard underlying global "lockdowns" was passed after maximum ONE day of peer review, as opposed to the average at that same journal of 172 days in 2019. Also that several authors have conflicts of interest. Unfortunately we were forced to cancel..

3/ because he was strongly advised by his university to maintain silence and not speak publicly -- to step back from this issue. I learned from a source that his university was heavily assailed by many complaints. Other scientists who have signed the review criticizing the PRC..

4/test, the "Retraction Request Letter", a critique that got worldwide attention, have also been bombarded with attacks, their relatives are being called at night, and their universities assailed. Some are at risk of losing jobs. Even former employers are being harassed. I..

5/ Note : scientists around the world are being silenced and harassed if they speak up in normal criticism of the scientific methods or conclusions used to advance the lockdown agenda and COVID testing. This is not post-enlightenment scientific discourse, this is how scientists
SCIENCE
Advertisement
Carlos E. Perez
Carlos E. Perez
@IntuitMachine
It is astonishing that most of cognitive science ignores an obvious reality. That there are two kinds of humans.

Tomasello has a very credible hypothesis that what distinguishes humans from the great apes is the inclination towards shared intentional behavior. What is innate is the disposition and like personalities, it is what defines our cognition as we grow.

If cognitive preference is so critical in cognitive development then why is it that we seem to have completely ignored the difference in cognitive preferences between men and women?

Humans are that species of primates that wandered out into the savannah. The savannah is different enough from a dense jungle to exert the evolutionary pressures that encourage the development of planning and forecasting skills.

Furthermore, human infants required a disproportional amount of effort to rear. This meant the specialization of roles between women who were responsible for rearing offspring and men who were responsible for bringing home the bacon. Failure in either implied death.
SCIENCE
Benedikt Kuhnhaeuser
Benedikt Kuhnhaeuser
@BenKuhnhaeuser
The calamoid palms 🌴 have over 500 species spread across the world, but their higher-level relationships were a bit of a mystery. Until now.

Out today in #MolecularPhylogeneticsAndEvolution:

A robust phylogenomic framework for the calamoid palms https://t.co/JiCbSUlheH

1/10


First some background info, so that you know what we are talking about:

Calamoid palms look a bit like snakes 🐍 (don't they!?!), because their fruits are covered in overlapping scales. And with their often fierce spines, they are equally fearsome. 😱

2/10


They are classified into 17 genera, 10 subtribes and 3 tribes. They have an amazing variety of growth forms, from stemless to climbing to tree habit. 🌱🌴

3/10


But as I said, their relationships have been a bit of a mystery. Here's the varying relationships previous studies found over the last 20 years.

4/10


We tackled this mystery with a phylogenomic approach: we sampled almost a thousand genes (a hundred times more than previous studies!) of 75 species representing all calamoid tribes, subtribes and genera.

The resulting data matrix is pretty massive...

5/10
SCIENCE
Dr. Richard Corsi
Dr. Richard Corsi
@CorsIAQ
1/ Automobiles and Intake Fraction. Since cars are back in the news I thought I would retweet this model result I offered in early April 2020. I focused only on 1 micron particles & accounted for windows completely closed & cracked slightly open.


2/ Related air exchange rates were based on experimental results in literature for mid-sized sedans. Particle deposition to indoor surfaces were accounted for, as the surface to volume ratio in a 3 m3 cab is large. An important outcome was the intake fraction (IF)

3/ Here, IF is the number of particles (or virions in collective particles) inhaled by a receptor DIVIDED BY the number or particles (or virions in collective particles) emitted by an infector.

4/ Integrated over the two hour drive (in this example) the IF for all windows closed & a receptor at rest is 0.08 (8% of what comes out of the infectors respiratory system ends up in the respiratory system of the receptor). 8%! That is a very high intake factor.

5/ With additional ventilation from cracking a window open drops the IF to 0.012 (1.2%) still relatively high. Can get lower by opening more windows.
SCIENCE

You May Also Like

ashkan soltani
ashkan soltani
@ashk4n
BREAKING: @CommonsCMS @DamianCollins just released previously sealed #Six4Three @Facebook documents:

Some random interesting tidbits:

1) Zuck approves shutting down platform API access for Twitter's when Vine is released #competition


2) Facebook engineered ways to access user's call history w/o alerting users:

Team considered access to call history considered 'high PR risk' but 'growth team will charge ahead'. @Facebook created upgrade path to access data w/o subjecting users to Android permissions dialogue.


3) The above also confirms @kashhill and other's suspicion that call history was used to improve PYMK (People You May Know) suggestions and newsfeed rankings.

4) Docs also shed more light into @dseetharaman's story on @Facebook monitoring users' @Onavo VPN activity to determine what competitors to mimic or acquire in 2013.

https://t.co/PwiRIL3v9x
TECH
Aditya Todmal
Aditya Todmal
@AdityaTodmal
The absolute best 15 scanners which experts are using.

Got these scanners from the following accounts:

1. @Pathik_Trader
2. @sanjufunda
3. @sanstocktrader
4. @SouravSenguptaI
5. @Rishikesh_ADX

Share for the benefit of everyone.

Listing all scanners from @Pathik_Trader Sir first.

1. Open

2. 80-20 Reversal Setup


3. Fake

4. Trapping Inside Bar (Positional Setup)
TECH , STOCKLEARNINGS , STOCKS
Advertisement
Anshul Pandey
Anshul Pandey
@Anshulspiritual
IMPORTANCE OF SATYA NARAYAN KATHA AND ITS ORIGIN.

We all have heard and read the Satyanarayan katha. But none of us dont know the original stories that Shatanand or Sadhu or Kalavati must have heard. Also, as a habit we hear or read this katha


but dont know the proper way it should be conducted.

We find its mention in Skanda puraan(Reva khand) and Bhavishya Puraan(Pratisarg parva).
Both Bhagwatam and Gita call Bhagwan Narayan as Satv or Truth. So Satyanarayan denotes this name as the one which is Truth incarnate.

The story began in Naimisharanya when Vyasji asked Sutji about a way to eliminate all the sorrows and fulfill all the desires and about who is the devta who can grant these at the same time.

So Suutji first prayed to Bhagwan Satyanarayan who is no one else but Vishnu ji.

Then he remembered all his avatars.After that he narrated the story of Narad. Once while visiting Mrityulok, Naradji was pained to see the sufferings of People around. He was deeply moved by these sufferings and wanted to know the means by which we could rid ourselves from these.

So he went to Vishnu ji and after paying his respects stood in front of him. Naradji narrated the purpose of his visit.

So Bhagwan Vishnu said to him that in Satyug and Tretayug, Bhagwan eliminates sorrow in Vishnuswarup. In Dwapar he assumes different forms to help people.
RELIGION
Aditya Todmal
Aditya Todmal
@AdityaTodmal
Master Thread of all my threads!

Hello!! 👋

• I have curated some of the best tweets from the best traders we know of.

• Making one master thread and will keep posting all my threads under this.

• Go through this for super learning/value totally free of cost! 😃

1. 7 FREE OPTION TRADING COURSES FOR


2. THE ABSOLUTE BEST 15 SCANNERS EXPERTS ARE USING

Got these scanners from the following accounts:

1. @Pathik_Trader
2. @sanjufunda
3. @sanstocktrader
4. @SouravSenguptaI
5. @Rishikesh_ADX


3. 12 TRADING SETUPS which experts are using.

These setups I found from the following 4 accounts:

1. @Pathik_Trader
2. @sourabhsiso19
3. @ITRADE191
4.


4. Curated tweets on HOW TO SELL STRADDLES.

Everything covered in this thread.
1. Management
2. How to initiate
3. When to exit straddles
4. Examples
5. Videos on
OPTION SELLING , OPTIONSTRATEGIES , CATEGORY
Professor
Professor
@DillikiBiili
Some ofthe biggest breakouts occur after Volatility Contraction, the analogy is that more a spring is pressed, higher it jumps whenever it gets released.

There is a VCP Scanner on chartink (Not mine). This may also be used to find potential Breakouts.
SCREENERS , TA SCREENERS