BC HEALTH
Saved by @CodyyyGardner

Can any MP ask the government why early treatment kits to stop viral replication & infection are not made available cheaply & prescription free in pharmacies as they are in India? Is it lives we want to save or is it Big Pharma profits? Because the two are mutually exclusive.

 There could even be competing kits, & the decision which to take could be left to doctors & patients, as happens with most medicines. The problem is that there is not one of these kits available cheaply & prescription free anywhere in the West.
Doxycycline, Ivermectin, Azithromycin, Hydroxychloroquine, Zinc, Vitamin D, Vitamin C, omega-3s, all approved as safe drugs decades ago. This is clearly not an issue of safety. It should be left to a doctor's experience & judgement whether they are effective or not, not academia.
A GP could simply state on his website: of all the kits I recommend Kit Z, then Kit Y etc. No need to wait hours for consultations, as soon as the symptoms are clear the self administered treatment begins, and thousands of lives are saved, as well as hospitals remain underwhelmed
There is no need to go to ER or ICU if people can buy early treatment kits from pharmacies. There is no need for any hospital to be overwhelmed. This problem could be resolved in days. There is simply no political will to save lives as it means to go against Big Pharma profits.
If it works in India, it can work everywhere else. The real question is do our politicians really want to save lives, or are they personally scared about the backlash from the Big Pharma lobby against saving lives cheaply & effectively? Recovery means immunity to severe Covid19.
Immunity against severe Covid19 means no need for vaccination. Acknowledgement that effective treatments exist means that vaccines are no longer emergency authorised drugs but need proper testing. The kit drugs are already tested & safe so in advantage over vaccines.
The pandemic would be over before the vaccines receive proper testing, & people willing to take them would be fewer. The early home kits would save thousands if not millions, the hospitals would not be overwhelmed. The solution is right here but the profit is not.
With early treatment home kits you sell at minimal profit to those who get the disease, which could be only 10% in any locality in total, with the vaccines you charge exorbitant amounts to public via governments & target 70% of the population, but its slow & slowness kills.
The profit interests of Big Pharma are mutually exclusive to the interest in saving lives whenever there is a fast evolving pandemic & the idea of vaccines is rolled out. They are by definition the wrong solution, as they are too slow. Early treatment is the right solution.
If the politician who represents you says they are interested in saving lives, please ask them to put pressure on government ministers to authorise early home treatment kits & make them available cheaply in pharmacies. This is how lives & social cohesion (no lockdowns) are saved.
@threadreaderapp pls unroll

More from Robin Monotti

Robin Monotti FRSA MA BSc
Robin Monotti FRSA MA ...
@robinmonotti
BAYES' THEOREM: The basic reason we get so many false positives to COVID19. The disease is so rare that the number of false positives greatly outnumbers the people who truly have the disease: THE MATHS:
https://t.co/oLHyxYJW9H


"Suppose that you are worried that you might have a rare disease. You decide to get tested, and suppose that the testing methods for this disease are correct 99 percent of the time"

"Suppose this disease is actually quite rare, occurring randomly in the general population in only one of every 10,000 people. If your test results come back POSITIVE, what are your chances that you actually have the disease? LESS THAN 1% chance that you have the disease!"


"The basic reason we get such a surprising result is because the disease is so rare that the number of false positives greatly outnumbers the people who truly have the disease"


Say mass testing of the contagious virus was done to 1 million people. In that million, 100 will really have the disease, 99 will be correctly diagnosed as having it. 999,900 of the million will not have the disease, but of those about 9,999 will be false positives! #BayesTheorem
CATEGORY C19
Robin Monotti MA FRSA\u2b50
Robin Monotti MA FRSA⭐...
@robinmonotti
"COVID-19 vaccines designed to elicit neutralising antibodies may sensitise vaccine recipients to more severe disease than if they were not vaccinated. Vaccines for SARS, MERS and RSV have never been

"data generated in the development & testing of these vaccines suggest a serious mechanistic concern: that vaccines designed empirically using the traditional approach (consisting of the unmodified or minimally modified coronavirus viral spike to elicit neutralising antibodies)"

"be they composed of protein, viral vector, DNA or RNA and irrespective of delivery method, may worsen COVID-19 disease via antibody-dependent enhancement (ADE)."

"This risk is sufficiently obscured in clinical trial protocols and consent forms for ongoing COVID-19 vaccine trials that adequate patient comprehension of this risk is unlikely to occur, obviating truly informed consent by subjects in these trials."

"Covid-19: vaccination roll-out correlates with worse mortality trends"
CATEGORY C19
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Robin Monotti
Robin Monotti
@robinmonotti
You know why they didn't try anything like this in the 1970s? Because a generation which remembered WW2 & were still strong enough would not have let them. Politicians were scared of people's reactions back then. They were literally scared for their lives. What happened?

Also, the State did not simply consist of politicians backed by a few regime journalists. There was a much stronger judiciary & military. We would already have seen the military remove deranged politicians leading any country into ruin like this.

The military would have turned against any government which indicated their role was to swab violate children or help inject people with unsafe experimental RNA altering drugs for a virus with a 99.7+% survival rate. They would have taken power by now. What happened?

The most important lesson we can teach our children are the lessons the parents who remembered WW2 taught theirs: how to say NO to a government that is going in a direction you disagree with before it's too late.

This has to start at refusing schools being turned into biosecurity propaganda outposts, asymptomatic testing stations, anti-science brainwashing institutions on masks, repeated swab violation of children's bodies for no gain & to artificially create false positive disruption
SOCIETY
Robin Monotti FRSA \u2b50
Robin Monotti FRSA ⭐...
@robinmonotti
Italian researchers: vaccines will not work against SARSCoV2 because this virus does not only replicate in human cells like other viruses, this one replicates through bacteria too. This is the fundamental reason why antibiotics work & vaccines will not:

Here is the Italian-EU scientific study indicating SARSCoV2 replicates in bacteria, not only human cells, and that is why antibiotics work and these vaccines will not:

"The preliminary results suggest that SARS-CoV-2 replicates in bacterial

2 of the 4 authors of the study work at the European Commission. Another works at an Italian medical research facility called Craniomed: https://t.co/EETSM3nb3T


You can find all of CRANIOMED's Carlo Brogna's published scientific research articles here, take a look:
CATEGORY C19
Robin Monotti
Robin Monotti
@robinmonotti
The problem with meta-analysis like this is that it obfuscates the most important issue of treatment, which is timing.


This meta-analysis of controlled trials only looks at hospitalized patients. How long were the patients ill for before being hospitalized? One week? Two? Three? Too late for zinc ionophores (HCQ) (+ZINC? No zinc no point..) to work. Severe illness becomes bacterial in nature.

Was azythromycin administered when the bacterial infections were also too advanced? I have seen Azythromycin work with my very own eyes but that's not to say that if administered too late it may not save the patient. How many patients were given AZT & ventilated? It's all timing.

All the meta-analysis is telling us is if you leave it too late you may have missed the early window for antiviral zinc treatment (Zn+HCQ) & that if you are given AZT when you are ventilated or very severe it may too late for it to save you & corticosteroids may be last resort.

And of course antibiotics need also probiotics, or they may harm the bacterial flora which is part of the immune response. Difficult to tell from a meta-analysis how this problem was managed.
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Dr. Joolz Denby\U0001f499
Dr. Joolz Denby💙...
@JoolzDenby
We’ve done menstruation, let’s talk about the menopause! Because only women however they present can have the menopause although men who have had treatments for prostate cancer can have symptoms mimicking the menopause. There’s nothing scary about

the menopause. It’s a perfectly natural function of the body but it’s tied up with a thousand stereotypes of women, ageism and ‘old women are frightening’. True, old women are often very frightening to young men because look! A woman who doesn’t give a rat’s

arse what you think of her now all her mating hormones have gone and with it your charm as a potential mate. Now you’re just another annoying lad. That’s gotta hurt. Menopause means Wisdom, like it or not and it’s not always nice or cosy. Old women

are encouraged to refer to themselves as ‘young at heart’ and ‘as young as you feel’ and other such crap and told to ‘never give in to age’ which is ludicrous. Cosmetic surgery is now a thing but I can tell you what the surgeons and marketing

men won’t - it does not make you look young. You’re just an old woman who looks like at best, she’s had a great holiday and at worst like she was was trapped in a wind tunnel. Old is good. Old is meritorious. Old is survival. Old means you didn’t die young
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James Salazar
James Salazar
@JamesSalazarMD
In medicine, reckoning with racism includes reappraising the very syntax we use every day. Proud to add my voice w/ @J_Ikeme and @RWGrantMD in this @JAMAInternMed pub addressing:

Does race/ethnicity belong in the first line of the patient

Some background: I’ve struggled with this question since early in medical school

Medical syntax is designed to communicate information in a predictable sequence with key elements prioritized to facilitate efficient communication and formation of an assessment and plan

2/

From preclinical lectures to Qbank questions to clerkship rotations, race/ethnicity was often prioritized in the same sentence as age + gender.

I grew accustomed to reading/hearing: a 70-year-old Black man w/ history of x, a 50-year-old Hispanic woman presented w/ y.

3/

However, when it came time for me to use race/ethnicity, there was always tension. Race/ethnicity are self/socially-ascribed identities that in clinical practice are almost always assumed by providers based on appearance. I was also concerned about the potential for bias

4/

I wondered how my own care would be impacted or not impacted by my ethnicity (Hispanic) – I have light skin so I’m not sure if my doctors would even identify me as such – but how would my care be different if I was presented as a 30-year-old Hispanic male?

5/
HEALTH
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Tony Breu
Tony Breu
@tony_breu
1/16
Why do B12 and folate deficiencies lead to HUGE red blood cells?

And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?

For answers, we'll have to go back a few billion years.


2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.

Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine

But why does DNA contains thymine (T) instead of uracil (U)?

https://t.co/XlxT6cLLXg


3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).

In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?

https://t.co/bIZGviHBUc


4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.

DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.

https://t.co/bIZGviHBUc


5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.

When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.

[*Note: thymine is the base in dTMP]

https://t.co/AnDUtKkbZh
HEALTH , PATHOPHYSIO
David Fisman
David Fisman
@DFisman
I do want to talk a bit about connections, conflicts and information during a pandemic. Since @fordnation insinuated I have COI which I don't, let's take a look at a single instance where @fordnation and Hospital for Sick Children are both making interesting decisions.

Both share a powerful supporter in Peter Gilgan, who has been a great supporter of Sickkids

But his company, Mattamy Homes, has also substantially bankrolled Ontario Proud, which I have reason to believe pushed the Postmedia hit on my reputation.


Sickkids and Mattamy have very close ties. Here is Mary Federau, a longtime Sickkids exec who has moved to Mattamy but remains involved with the Sickkids foundation:


Mary's bio is too modest. It looks as though it has been scrubbed a bit over the last 72 hours. Here's the google cache from Jan 25:
HEALTH
F. Perry Wilson, MD MSCE
F. Perry Wilson, MD MS...
@fperrywilson
Folks, we need to talk about this Vitamin D trial. I have no stake in this game - take Vitamin D if you want but this pre-print is super sus.

The paper is presented as a randomized trial of vitamin D supplementation in hospitalized patients with COVID. Interesting and important question! And the results appear dramatic:


If true, this would be one of (if not THE most) effective treatments for COVID. But there are problems...

The first clue something is up is that the randomized groups aren't the same size:


It took me a while to figure out why this was, then I saw in the text that INDIVIDUALS were not randomized, WARDS in the hospital were.
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