1/ An excellent new paper from Denmark that tracks every vaccination given to nursing home residents there shows an 40% RISE in infections immediately after the first @pfizer dose and no efficacy at any point. Protection in this population after “full” vaccination is 64%...

2/ The researchers also tracked health-care workers, the other group in Denmark to receive the vaccine first. They actually had an even LARGER rise in infections immediately following dose 1, but overall higher protection at “full” vaccination (a week after dose 2) - 90%...
3/ This paper is the best yet (because it’s the least political). It is also in line with the Israeli and English data show once you wade through their spin. The takeaways are: The vaccine is much less effective in the people who need it most and DON’T DELAY THE SECOND SHOT...
4/ By the way, i#depending on how long the vaccine provides protection, its OVERALL effectiveness will be below whatever the peak figure is, maybe well below - you need a lot of good weeks to make up for that bolus at the beginning - but I don’t even want to go there.
5/ This paper also shows why the raw Israeli numbers are trash - if infections are declining overall (as they were in Israel and Denmark in February) looking at infections in the vaccinated population without adjusting for that trend markedly overestimates the vaccine effect.
6/ One last point: vaccine efficacy is also overestimated on a population basis because the Israeli and Danish data show about 10% of elderly people get one dose but not the second, presumably because they couldn’t tolerate it. So they get all the downside and none of the upside.
7/ They are also not counted as fully vaccinated, which makes the vaccine numbers look better.

Source: https://t.co/RtyNiWlfXL

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