BC SOCIETY
Saved by @ThomassRichards

1/ Today has brought a lot of news about 'variants', as we discover community transmission of B.1.351 (SA variant) in the UK.

But some of the people who study these genomes have increasingly started focusing on a different concept: 'constellations', which may be more useful.

 2/ We're actually all using 'variant' wrong anyway – we're using it to refer to a 'lineage'. A lineage is a set of viruses descended from a common ancestor. All B.1.1.7 (UK variant) viruses descend from an infection that probably occurred in August or September.
3/ But what makes this lineage practically important is that it carries a set of mutations which make it more transmissible.

I.e. we don't really care about the ancestry in itself.
4/ For example, one of the mutations that we think is important to B.1.1.7's faster transmission is called N501Y.
5/ It turns out that a lot of the lineages identified as important recently, in Brazil, South Africa, and the UK, have mutations such as N501Y in common (figure adapted from https://t.co/lpJeW0GGnU)
6/ You can see in the table that the lineage originating in South Africa, and those originating in Brazil, have another mutation, called E484K, in common.
7/ Today PHE's Technical Briefing 5 reveals that a small number of B.1.1.7 (UK lineage) genomes have recently been found which newly carry the E484K mutation, which had previously been seen in these South African and Brazilian lineages.
8/ This shows why thinking about constellations is useful. A 'constellation' is just a set of shared mutations carried by viruses, irrespective of ancestry.
9/ Should we treat B.1.1.7+E484K cases as less concerning than viruses descending from those that originated in South Africa?
10/ We don't know the answer to that one way or another. We don't know to what extent E484K is the key mutation to driving the properties of a lineage, and we don't know how this mutation might interact with other mutations B.1.1.7 carries.
11/ But increasingly, it's going to be important to focus on the mutations that viruses carry, and understanding what effect these have, rather than simply focusing on their ancestry.
12/ From everything we have seen across the continents, E484K seems significant, and we should be very alert to its emergence in another lineage with high transmissibility. (There's every indication that the public health authorities are alert).
13/ Here's some more on constellations: https://t.co/dOzmEG5Vju
(I regret saying the use of 'variant' was 'wrong' above, it's all very fuzzy!)

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SocialCops’ 10 (base 10) Engineering Commandments — the values that drive everything for the #Engineering Team #InsideSocialCops 🙌

(Thread👇) Tell us if you can relate to any of these? Do you have your own values that guide your decisions? Share them with us! ⛳

0. Coder != engineer

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@_Miatonin @AOC Based on the present evidence, it is reasonable to suggest that biological, psychological, and sociocultural factors contribute to the range of gender gaps observed across sports.

@_Miatonin @AOC Men and women exhibit similar relative responses to resistance training, with no gender-specific responses noted after 10-weeks of resistance

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Nearly a year ago, the Tablighi Jamaat controversy took over India’s media. Around 3,500 foreign nationals had visited India to attend the Tablighi Jamaat event at the Nizamuddin Markaz Mosque in Delhi.

With the lockdown being announced on March 24, 2020, several attendees had moved to different parts of the country to attend smaller gatherings in local mosques.

Around 960 foreign nationals were held at quarantine and in states like UP, Jharkhand, Maharashtra, Karnataka, etc. were sent straight to prison.

There was an outpour of Anti-Muslim bigotry in much of Indian news media with this event where it ramped up its demonisation of the community.

For weeks, the attendees of the Tablighi Jamaat event were named the “super-spreaders” of COVID and in several cases, Maulana Mohammad Saad was called a terrorist and “the maulana of death”.
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Southerners wrote songs about Warrington, formed peace movements because of IRA violence - but I can’t point to any mainstream effort to oppose/understand who the glenane gang, or Shankill butchers were, care about Loughinisland, state violence, &collusion.
V selective interest

They were and are revolted by SF glorifying murder but dont know or care about the deaths of catholics here. As I’ve seen the apathy to the life my parents lived, and the fear I grew up with, I always make it understood I’m Irish but from the north. Because it’s important

Showing absolutely no interest in the murder of the people in the areas SF are elected to represent is really selectively deciding whose lives you think are worth anything. I doubt anyone south of Louth Monaghan or Cavan could tell you or care about the Reavey brothers

There was and is no hand wringing about children being shot in the fields by soldiers in front of their parents or hunted down in their own house and killed in front of their families- where were the marches, the songs, the movements?

“But Sinn Fein said this”- is of zero comfort to victims of state or loyalist violence and you are actually framing their loved ones murders in such a way that you’re almost making them partially culpable for their own fate or excusing it somehow when it’s nothing to do with SF
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A #story from #Thiruvilayadal puranam-one of divine leelas of Bhagwan Shiva

#threadseries #Madurai

Story 16- it is about how Bhagwan Shiva explained the meaning of Vedas to the Rishis.

வேதத்துக்குப் பொருள் அருளிச் செய்த படலம்


Once there was a great deluge,everything in the world was destroyed.All lifeforms that existed got perished.Afterwards ,due to Bhagwan Shiva creation started.Then from Bhagwan Shiv ji's mouth-birth of 🕉 OM- Pranavam happened.From Pranavam,4 vedas appeared. Rishis learned them.

Many Rishis in Naimisharanya learned Vedas&recited them but they didn't understand the meaning&essence of Vedas. They were worried as they couldn't find any guru who can teach them the meaning of Vedas.That time,Rishi Arabhatar visited them.Rishis told him about need their worry.

Rishi Arabhatar told them that Bhagwan Shiva has given Vedas &he would be grateful enough to teach the meaning as well.But for that rishis have to rigorous penance at a sacred place.Also told them to go to Sundareswarar temple in Madurai to do tapas in front of Dakshinamurthy.

Assured them that Dakshinamurthy himself will come & teach them.Rishis proceeded to Madurai & started their tapas in front of Dakshinamurthy sannidhi for almost a year starting from Karthigai month pournami to next year Karthigai month pournami following all rituals..annadan
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1/ Here’s a list of conversational frameworks I’ve picked up that have been helpful.

Please add your own.

2/ The Magic Question: "What would need to be true for you


3/ On evaluating where someone’s head is at regarding a topic they are being wishy-washy about or delaying.

“Gun to the head—what would you decide now?”

“Fast forward 6 months after your sabbatical--how would you decide: what criteria is most important to you?”

4/ Other Q’s re: decisions:

“Putting aside a list of pros/cons, what’s the *one* reason you’re doing this?” “Why is that the most important reason?”

“What’s end-game here?”

“What does success look like in a world where you pick that path?”

5/ When listening, after empathizing, and wanting to help them make their own decisions without imposing your world view:

“What would the best version of yourself do”?
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What happens when you have:
Netflix
Apple
Amazon
WarnerMedia +
Disney+
SonyCrackle (Reboot)
Verizon All Access (after they buy CBS/Viacom)
UniversalSkyMedia
By 2021
Answer? Internet Slows To A Craw and Dies.
Why?
Bandwidth.

Netflix's gets 35% of all internet traffic.
Now we all know Apple Coming to Netflix Corner.
We know that WarnerMedia Planning One
We Know about Disney+
Now how will the net handle 8 Streaming Platforms all at once?
Answer - IT CANT.

But Novid, the speed, the 4K the all everything?
NOOOOO BUDDY.
Even if you could do it and even if AWS ran six million clouds, The Net Will still slow to a crawl. 35%, goes to nearly 90% if any of the 8 or all of the 8 eat at netflix's numbers.

Oh, they wouldn't be running at once.
FOOL. You forget how bad things were when game of thrones season premieres came around. HBO SERVERS FALL DOWN GO BOOM!

Now see if a season like 2021 come around and they air shows on a same day. It gets crazy. AT&T and others gonna realize they cant build out forever. Something will give and it might be your entertainment consumption big time.
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