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More from NotTheMacAnon

Transduction is the process by which foreign DNA is introduced into a cell by a virus or viral vector.

Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells.

Viruses have evolved?

specialized molecular mechanisms

to efficiently

transport their genomes

inside the cells they infect.

Delivery of genes, or other genetic material, by a vector is termed transduction and the infected cells are described as transduced.

A transducer is a device that converts energy from one form to another. Usually a transducer converts a signal in one form of energy to a signal in another.

NotTheMacAnon
@NotTheMacAnon1

Localized Surface Plasmon Resonance - an overview | ScienceDirect Topics

https://t.co/mzS7vVSREJ

https://t.co/353PdAX2fa

https://t.co/3yBImjOdd4

In some cases, almost 100% of the light energy can be converted to the second harmonic frequency. These cases typically involve intense pulsed laser beams passing through large crystals, and careful alignment to obtain phase matching.

NotTheMacAnon
@NotTheMacAnon1

👍🏻

"When does a canary sing"

See thread RT on oxidative stress and QD effects.
Thank you @NotTheMacAnon1 https://t.co/XlyXyiCS2H
— Found&Forgiven (@AshlieMC2) December 7, 2020

https://t.co/0ywQ1y5NDj

Pott found an association between exposure to soot and a high incidence of scrotal skin cancer in chimney sweeps. This cancer is now known as Pott's or chimney sweep cancer.

Coal contains trace amounts of naturally-occurring radioactive elements. The process of burning coal at coal-fired power plants, called combustion, creates wastes that contain small amounts of naturally-occurring radioactive material (NORM).

Fly ash particles (a major component of coal ash) can become lodged in the deepest part of your lungs, where they trigger asthma, inflammation and immunological reactions.

NotTheMacAnon
@NotTheMacAnon1

So where are we at with this virus people?

NotTheMacAnon
@NotTheMacAnon1

This nonspecific cation channel opens when illuminated with blue light, depolarizing the cell [4, 6] to trigger action potentials cells with high temporal precision [5]. Since the initial discovery of ChR2, many modifications have been made to refine the kinetic properties.

For example, ChETA, engineered to address limitations of spike fidelity with ChR2, has faster temporal kinetics and can maintain reliable spike precision up to 200 Hz [7].

Halorhodopsins (NpHR), light-gated chloride pumps activated by yellow light, allow for temporally specific hyperpolarization with single spike precision [8–10].

Archaerhodopsin-3 (Arch), a yellow light-activated outward proton pump, is an increasingly popular tool for light-induced hyperpolarization to inhibit cellular activity. Arch recovers spontaneously from inactivation with a much shorter recovery time than NpHRs [11].

Arch currents continue to increase with increasing light intensity, while NpHRs saturate [11]. The increased light sensitivity of the ArchT variant, along with better membrane targeting, allows for improved neural silencing both at cell bodies and terminals [12].

More from Science

Jason Hickel
@jasonhickel

Here's more on the new mitigation scenario for 1.5C. How does it work? What would society look like? Are we willing to do what's required to stop climate breakdown? See thread.

1. Most models assume we need to keep growing the economy indefinitely. The problem is this makes it impossible to transition to zero emissions quickly enough; so they speculate on geoengineering and negative-emissions technologies to save us. Scientists reject this as too risky.

2. By contrast, this scenario proposes that high-income countries don't *need* more growth, and can scale down unnecessary production and consumption. This reduces energy demand (from 140 EJ in 2020 to 40 EJ in 2050), and enables a rapid transition to renewable energy.

3. What does it require? In the global North (Annex 1 countries)
•a shift from private cars to public transportation
•reduction in flights
•smaller average house size

Meanwhile, consumption in the global South (non-Annex 1 countries) rises to converge.

4. Significant reduction of aggregate material use. How? Longer product lifespans; regionalization of production and consumption; ban on advertising; a shift in taxes from labour to resources. All of this allows us to reduce ground freight, which cuts energy use.

Kevin McKernan
@Kevin_McKernan

When respected Scientists resign over the false narrative... Take notice... and thank them.

Google Translated Letter from

Prof. Dr. Thomas Aigner,
Department of Geosciences,
University of Tuebingen, Sigwartstrasse 10,
D-72076 Tuebingen Germany

Dear colleagues,
It was with the greatest astonishment, deepest concern, and indeed bewilderment, that I took note of the "7th ad hoc statement" from the National Academy of Sciences Leopoldina on December 8th, 2020.
In my opinion, this paper is not worthy of an honest, critical-

weighing science oriented towards the service and well-being of man. I do not have any medical expertise. However, as a scientist committed to nothing but the pure truth, I take the liberty of speaking up. I feel very alarmed by several points:

1. On November 27, 2020, a group of 22 internationally recognized experts presented the following report on the PCR test, the linchpin of the "pandemic", for the Eurosurveillance magazine:

"External peer review of the RTPCR test to detect SARS-CoV-2 reveals 10 major scientific flaws at the molecular and methodological level: consequences for false positive results". Quote: "This highly questions the scientific validity of the test".

Dr Naomi Wolf
@naomirwolf

1/Just had an interview scheduled with @goddeketal, Dr Simon Goddek, the post-doctoral researcher at the Faculty of Mathematics and Statistics in the field of biotechnology, at an unnamed Dutch university. This researcher has been publicly pointing out that the paper that...

2/ the PCR test as the gold standard underlying global "lockdowns" was passed after maximum ONE day of peer review, as opposed to the average at that same journal of 172 days in 2019. Also that several authors have conflicts of interest. Unfortunately we were forced to cancel..

3/ because he was strongly advised by his university to maintain silence and not speak publicly -- to step back from this issue. I learned from a source that his university was heavily assailed by many complaints. Other scientists who have signed the review criticizing the PRC..

4/test, the "Retraction Request Letter", a critique that got worldwide attention, have also been bombarded with attacks, their relatives are being called at night, and their universities assailed. Some are at risk of losing jobs. Even former employers are being harassed. I..

5/ Note : scientists around the world are being silenced and harassed if they speak up in normal criticism of the scientific methods or conclusions used to advance the lockdown agenda and COVID testing. This is not post-enlightenment scientific discourse, this is how scientists

Michael Wara
@MichaelWWara

Ever since @JesseJenkins and colleagues work on a zero carbon US and this work by @DrChrisClack and colleagues on incorporating DER, I've been having the following set of thoughts about how to reduce the risk of failure in a US clean energy buildout. Bottom line is much more DER.

Rooftop solar can play a key role in a transition to 100% renewable energy - and it can help American's pocketbooks #GoSolar https://t.co/6p9jb62EGW
— Environment America (@EnvAm) January 14, 2021

Typically, when we see zero-carbon electricity coupled to electrification of transport and buildings, implicitly standing behind that is totally unprecedented buildout of the transmission system. The team from Princeton's modeling work has this in spades for example.

But that, more even than the new generation required, runs straight into a thicket/woodchipper of environmental laws and public objections that currently (and for the last 50y) limit new transmission in the US. We built most transmission prior to the advent of environmental law.

So what these studies are really (implicitly) saying is that NEPA, CEQA, ESA, §404 permitting, eminent domain law, etc, - and the public and democratic objections that drive them - will have to change in order to accommodate the necessary transmission buildout.

I live in a D supermajority state that has, for at least the last 20 years, been in the midst of a housing crisis that creates punishing impacts for people's lives in the here-and-now and is arguably mostly caused by the same issues that create the transmission bottlenecks.