BC HEALTH
Saved by @CodyyyGardner

I tweeted yesterday about clinical engineering and the vital role they play and had a reminder about all the other incredible staff in the NHS that no one ever hears about and so to try and change that

NHS Covid unsung heroes list

 Perfusionists - magicians. From the crucial role they play in cardiac surgery to the unbelievable role they have in providing ECMO (using the machine below) to the sickest covid-19 patients. Barely anyone knows about them but they are an incredible profession.
Estates - built new high dependency and intensive care areas almost overnight in hospitals up and down the country. They make what often seems impossible happen and we would not be able to treat as many patients without them and their vital work.
Laboratory scientists - I dread to think how many samples they receive and process each day but we absolutely cannot care for patients without them and their technical skills. Their workload has soared and they are working consistently flat out.
Porters - the backbone of the hospital. The transferring patients, running samples, getting blood, making the impossible happen staff that simply keep the hospital running.
Cleaners and domestic staff - how can you not appreciate the essential work they do in keeping patients and staff safe? They are the absolute frontline in preventing spread of infections and do the most crucial of roles.
Ward clerks and administrative staff - the NHS would collapse without their organisation. Trying to organise anything in the NHS can feel a little bit like herding cats but they navigate systems and make stuff happen.
Mortuary workers - the past months have been hellish for them but they continue to do their job with kindness and the upmost respect for the deceased patients they are caring, and it definitely is care.
Switchboard staff - directing calls, putting out emergency calls, dealing with such a higher workload now families sadly can’t visit in many areas. They are a vital part of getting teams to emergencies across the hospital.
Catering staff - bringers of food and cups of tea and so often kind words and compassion to patients who are sadly isolated from their loved ones.
Pharmacists - from checking patients drugs and interactions to advising on medications and complex regimens to dispensing and making up incredibly complex infusions - a core part of the team yet hugely under recognised for the vital work they do
Play specialists - supporting children through all sorts of procedures and operations with skill, kindness and laughter. A crucial part of the paediatric team and always the most consistent supply of bubbles in any hospital!
I am going to kick myself as I remember other groups and will add to this thread but if others want to kick me and remind me please do!!
But most of all thank you all for the incredible jobs you do!!
Speech and language therapists - improve the quality of life for the patients that need them day in day out. Assessing swallow, advising on diet, supporting removal of tracheostomies, improving speech....a complex and varied role that has a huge impact for patients.
Radiographers - from X-rays to CT scans to MRIs to ultrasound and every modality in between - performing huge numbers of investigations that guide the care of patients and they have been working tirelessly throughout this pandemic. We couldn’t do without them.
Physiotherapists - the role they play in the rehabilitation of patients is mind blowing - from providing chest physio and weaning plans in ITU to helping patients mobilise and gain strength to helping patients go home to their loved ones. Just astonishing
Occupational therapists - supporting patients in a huge number of varied ways to live their lives and improve the quality of that. Their expert assessments, treatment plans and use of different equipment can be truly life changing after illness or injury.
Informatics - using data and making it meaningful to guide clinical and operational decision making. The insight their work gives is extraordinary and supports all sort of the healthcare system and yet they go often so unnoticed
IT - I apologise to them for every time I have managed to lock myself out of a system but they do so much more than that. Building new systems, installing new hardware, making sure we can do our jobs by providing expertise across a huge number of areas.
Procurement - their role in ensuring we all have access to PPE cannot be downplayed but they do so much more that goes unseen to make sure staff and patients have the resources and equipment needed. Staggering given how much stuff we use daily!!
Told you all I needed help and please keep the suggestions coming!!
ODPs - now in my defence I tweet about my love for them regularly but I will add it here again because could not do my job without them. When an ODP ever says “have you thought about....” or hands you a bit of equipment it is always a godsend.

#loveyourODP
Phlebotomists - masters of the dark art of getting blood samples from the patient with even the trickiest of veins (and I include myself in that so sorry!).
Vascular access team - literal life savers when it comes to patients with tricky access or the need for longer term lines such as PICC lines. Learn a huge amount from them every time I am fortunate enough to see them out in a line.
Dieticians - their knowledge bank is incredible and what they do makes a huge amount of difference to how patients recover from illness. From advising patients through to incredibly complex decisions around TPN - just amazing!
And yes - hospital volunteers play an absolutely wonderful role and the support they give can never be underestimated. A huge huge thank you for the time and dedication you all bring and for making the NHS just that but more special through what you do each day!
Clinical engineering and medical physics - currently at a hospital which has 24/7 clinical engineering on site and my respect for the incredible work they do has never been higher. Sorting out the myriad of clinical equipment, medical gases and everything inbetween.
Turns out it is really hard to compile such a list when at home and desperately trying to think of everyone to add!!
Medical librarians - providing expert support in identifying new literature to support patient care and whizzes at finding invaluable clinical information to help teams care for patients. Especially vital when we were dealing with a virus we knew barely anything about!
Medical education teams - almost overnight putting on courses and finding resources to support staff who were redeployed, their role in training staff can never be overlooked.
Security staff - personally a huge thanks for helping every time I have needed them but keeping us all safe day in day out - thank you doesn’t seem enough
Research teams - trials change practice and improve patient care and we have seen just how vital that is during this pandemic. Research is one of the most important things we can all be part of to improve the care for patients now and in the future.
Apologies to any groups not included and that doesn’t mean you aren’t hugely valued but hope this thread has given a flavour of the huge variety of those working in the NHS. So often hear about doctors and nurses but hope this opens people’s eyes to other amazing varied roles!
Other teams include HR, payroll, finance teams, and because @DavidKovar1 will never forgive me if I forgot - our amazing managerial teams - honestly we couldn’t do our clinical jobs without each of these roles and it is one of the joys of the NHS that I do get to work with them
And a huge special thanks to all those supporting patients and their relatives, perfect example are psychologists and chaplains have played an absolutely vital role and whose importance can never be overlooked.

More from Health

Gregg Gonsalves
Gregg Gonsalves
@gregggonsalves
Eight years ago, Spencer Cox died of #AIDS. He had access to #antiretroviral therapy, but in his own struggles with #depression and substance use, he stopped taking them. 1/

Spencer left college, dropped out like me in the 80s, and we both found ourselves in @actupny where we joined the Treatment and Data Committee, doing battle with drug companies, the @US_FDA, the @NIH on a quest to save ourselves and our friends from near-certain death. 2/

Now everyone knows what those dark days before the advent of antiretroviral therapy were like. Waves upon waves of dying friends. A government who couldn't care less for the sick and dying. 3/

All this has happened before, and all this will happen again. AIDS. #COVID19. The next pandemic. The fire next time. 4/

And it changes you. Seeing so much death so young. Seeing those in power turn away from the catastrophe, even joke about it (find, listen to the tape of Larry Speakes in Oval Office w Reagan laughing about AIDS). 5/
HEALTH
Alex McNeil
Alex McNeil
@AlexMcNeil14
Masks. A short thread. In June last year my GP advised me that wearing a mask even for a short space of time would be harmful for me on two fronts. One - I have painful rosacea on my face. It’s a horrible condition and it’s lifelong. I can at times look scary!

Putting on a mask simply makes it worse. Two - I have hypertension. Manageable and controlled. GP also advises that mask wearing even for short periods can raise cortisol levels and make them dangerous to me.

On that basis and given the dreadful treatment us non-maskers have to suffer and to appease the abusers I have three times asked my GP to issue me with a letter relating to my conditions.

On each occasion she has said that there is no need. Whilst she won’t admit it straight up, all conversations suggest she’s been told not to. I happen to agree that no-one should need to reveal their medical history to anyone other than medical professionals responsible for me.

I’ve researched mask wearing in relation to what they are supposed to be used for ref *Covid* - I’m no thicko - I prepare risk assessments (and I’m qualified to do so) every day (or did) - and the evidence *for* is weak. Very weak.
HEALTH
Advertisement
Tony Breu
Tony Breu
@tony_breu
1/16
Why do B12 and folate deficiencies lead to HUGE red blood cells?

And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?

For answers, we'll have to go back a few billion years.


2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.

Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine

But why does DNA contains thymine (T) instead of uracil (U)?

https://t.co/XlxT6cLLXg


3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).

In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?

https://t.co/bIZGviHBUc


4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.

DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.

https://t.co/bIZGviHBUc


5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.

When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.

[*Note: thymine is the base in dTMP]

https://t.co/AnDUtKkbZh
HEALTH , PATHOPHYSIO
NortherlyRose \U0001f308 \U0001f499
NortherlyRose 🌈 💙...
@NortherlyRose
#Thread

Living with meltdowns.

A personal, very late diagnosed, autistic perspective.

#autism
#AllAutistics
#ActuallyAutistic

1/

Before my autism diagnosis I had occasional emotional outbursts. These generally happened at home after a sustained period of pressure at school or at work.

When I discovered I was autistic I realised that these were actually what people call meltdowns.

2/

Getting intensely upset was a bit of a family thing. Sudden shouting and throwing of things, with resumption of peace and calm afterwards, wasn’t that unusual.

In fact we had a kind of mantra that it was much better to express our emotions than to keep them bottled up.

3/

It was hard to gauge my own emotions against other people’s but by any measure I felt things incredibly intensely.

As a child the injustice of being told off for something that wasn’t my fault burned into me. I sobbed until the tears stang my face and I could hardly breathe.

4/

But suppressing emotion was necessary for me to survive in the outside world. That’s partly what led to uncontrolled outbursts of feelings at home.

I melted down because there was no justice and I’d been misunderstood. I wasn’t using emotion as some kind of bargaining tool.

5/
HEALTH
Dr. Tory Eisenlohr-Moul, PhD \U0001f3f3\ufe0f\u200d\U0001f308
Dr. Tory Eisenlohr-Mou...
@eisenlohr_moul
Want to include the menstrual cycle in your scientific work, but aren't sure how to do it? My lab (@katjaschmalen) have just published an article on best practices for observational studies of the cycle! Thread below! 🧵

Despite decades of research on the menstrual cycle, empirical studies have not adopted consistent methods for operationalizing the menstrual cycle, resulting in confusion in the literature and limited possibilities to conduct systematic reviews and meta-analyses.

Below, I summarize this "how to" article, and relay some of the key points!

PARTICIPANTS: All participants should be naturally-cycling people with ovaries (remember that they are not necessarily "women"! 🏳️‍⚧️ ⚧).

We provide a Reproductive Status Questionnaire with rules for identifying naturally-cycling people (current function of the sexual organs and hormonal/other medications that stop the cycle).
HEALTH

You May Also Like

SK
SK
@sk_diary1
#DoYouKnow -The place where
Lalitha Sahasranamam -1000 names of Devi originated.

It is in Lalithambigai temple -Thirumeeyachur,Near Mayiladuthurai,TN

There is a Legend #story & it is related to this beautiful #sculpture of Kshetrapuraneswarar & Ambal Lalithambigai #Thread 👇


#Legend #story
It is believed that this is birth place of Kashyapa Maharishi’s sons, Arunan& Garudan. Arunan(charioteer of Surya)was physically handicapped.He was a Shiva devotee.Arunan wanted to visit Kailash to have Shiva Darshan,but Surya Dev denied permission.

So Arunan disguised as a girl & was on his way to Kailash.On the way Surya Dev saw this girl & outraged her modesty.Shiva was very angry with Suryan for misbehaviour & cursed him to get darkened. Whole world plunged into darkness.Surya Dev pleaded to Bhagwan Shiv to forgive him.

Shiva Bhagwan asked him to go to Thirumiyachur & worship him there. As advised, Surya Dev performed rigorous penance, placed murthi of Shiva& Parvathy on an elephant & took them to the clouds.Shiva in this temple is known as Meganathaswamy,Devi is known as Lalithambigai


Even after severe penance,Shiva does appear,so Surya Dev cries out in agony.Disturbed by his call, Parvathy protests.Siva pacifies her & offers relief to Surya Dev.The sculpture of Shiva pacifying Ambal shows her sullen from one angle &smiling from another.
RELIGION
Aditya Todmal
Aditya Todmal
@AdityaTodmal
Boss is always Boss @Mitesh_Engr

Mitesh Sir's FUTURES BREAKOUT TRADES 101:

• How to pick stocks at right time?
• What to look for?
• Importance of BO post consolidation
• How to manage SL
• How to get huge profits
• Multiple Examples

In collaboration with @niki_poojary


Importance of Trading only BO or BD stocks by @Mitesh_Engr Sir: 👇

•Two questions to always ask:

~Why stock is going up/down and when?
~ Who is behind big up/down and when?

• Trade only stocks with Momentum
• Instant results
• Small SL or huge profits


Sir's take on how to Trade: 👇

• Observe fight between buyer & seller
• Position will be created within first 3 hours
• Operators will win
• Just find BO or BD
• Look for huge volume support
• Give company to operators
• ATP importance explained


How to take trade in Breakout/Breakdown stocks by @Mitesh_Engr Sir: 👇

• Check Support & Resistance
• Wait for 2-3 months consolidation
• Surge in volumes
• Trade on 3 min charts
• Small SL
• Keep trailing
• Always pyramid in profit


When and Why to Pyramid? By @Mitesh_Engr Sir

• Adding to winning positions
• Signals of continued strength
• Potentially large profits
• An Example of pyramiding in one of his trades
MPLEARNINGS , ALL , MPTRADERULES
Advertisement
Kieran Snyder
Kieran Snyder
@KieranSnyder
1 There's a chasm between an NLP technology that works well in the research lab and something that works for applications that real people use. This was eye-opening when I started my career, and every time I talk to an NLP engineer at @textio, it continues to strike me even now.

2 Research conditions are theoretical and/or idealized. A huge problem for so-called NLP or AI startups with highly credentialed academic founders is that they bring limited knowledge of what it takes to build real products outside the lab.

3 A product is ultimately a thing that people pay for - not just cool technology or user experience. But I’m not even talking about knowledge gaps in go-to-market work. I'm talking purely technical gaps: how you go from science project to performant + delightful user experience.

4 Most commoditized NLP packages solve well-understood problems in standard ways that sacrifice either precision or performance. In a research lab, this is not usually a hard trade-off; in general, no one is using what you make, so performance is less important than precision.

5 In software, when you’re making something for real people to use, these tradeoffs are a big deal. Especially if you’re asking those people to pay for what you’ve made (can’t get away from that pesky GTM thinking). They expect quality, which includes precision AND performance.
MACHINE LEARNING
Daoyu
Daoyu
@Daoyu15
@franciscodeasis https://t.co/OuQaBRFPu7
Unfortunately the "This work includes the identification of viral sequences in bat samples, and has resulted in the isolation of three bat SARS-related coronaviruses that are now used as reagents to test therapeutics and vaccines." were BEFORE the


chimeric infectious clone grants were there.https://t.co/DAArwFkz6v is in 2017, Rs4231.
https://t.co/UgXygDjYbW is in 2016, RsSHC014 and RsWIV16.
https://t.co/krO69CsJ94 is in 2013, RsWIV1. notice that this is before the beginning of the project

starting in 2016. Also remember that they told about only 3 isolates/live viruses. RsSHC014 is a live infectious clone that is just as alive as those other "Isolates".

P.D. somehow is able to use funds that he have yet recieved yet, and send results and sequences from late 2019 back in time into 2015,2013 and 2016!

https://t.co/4wC7k1Lh54 Ref 3: Why ALL your pangolin samples were PCR negative? to avoid deep sequencing and accidentally reveal Paguma Larvata and Oryctolagus Cuniculus?
ALL
Elon Musk\u2019s Meme \U0001f171\ufe0fot
Elon Musk’s Meme 🅱️ot...
@theMemesBot
Thats a gg, Satan
FUN