Sarcomeres in cardiac myocytes (heart muscle cells) are mechanically coupled to focal adhesions through dorsal stress fiber-like structures. #cardiotwitter #CellBiology
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A thread based on Figure 1

Starting my 2nd thread on Sringeri Parampara. This will cover the Jagadgurus after Sri Vidyaranya to Sri Shivabhinava Nrisimha Bharati.

It is really very tough to match the brilliance and achievements of Vidyaranya. After whom came 15 - Chandrashekara Bharati [1386-1389].

The next Acharya was Nrisimha Bharati [1389-1408]. Harihara raya found a town for this Acharya - Narasimhapuram. Acharya helped the king by guiding him in political affairs. He also initiated the kind with mahamantras for spiritual development.

Subsequent Acharyas were
15-Puroshottama Bharati [1408 - 1448]
16-Shankara Bharati[1448 - 1455]
17-Chandrasekhara Bharati II [1455 - 1464]
18- Nrisimha Bharati II [1464 - 1479]
19-Puroshottama Bharati II [1479 - 1517]

20-Ramachandra Bharati [1517 - 1560]. Sadashiva Raya was emporer of Vijayanagara during this time.
21-Nrisimha Bharati III [1560 - 1573]
22-Nrisimha Bharati IV [1573 - 1576]
23-Nrisimha Bharati V [1576 - 1600]

24-Abhinava Nrisimha Bharati [1600-1623]. When he visited Malahanikareswara temple for first time he noticed there was no Vinayaka there so he took piece of turmeric and drew outline of Ganesha on a pillar and offered puja.

ADI SHANKAR AND SRI TOTAKACHARYA

Adi Shankaracharya chose his disciple Totakacharya to be the first head of the Math at Joshimath.
The Narsingh Mandir (Mandir of Sri Narasimha) in Joshimath is one of the 108 Divyadesams and also the home of Badrinath during the winter months.

Totakacharya was earlier a boy named ‘Giri’ and a devout disciple of Adi Shankaracharya. Unlike others, he was not known to be an expert in Shastras but his dedication to his Guru was complete and he used to listen to His discourses with utmost faith and devotion.
@SriRamya21

One morning as Adi Shankara and his disciples were getting ready for the discourse, Giri was delayed. The other disciples urged their Guru to commence the lesson on Bramhsutra Bhashya telling him that Giri would anyway not be able to comprehend its deep meaning.
@RajeAiyer

Adi Shankar responded “नायमात्मा प्रवचनेन लभ्यो न मेधया” – Atman cannot be attained through discourses or mere intellect.
He,then, awakened the supreme knowledge in Giri.
Giri spontaneously composed: श्री शङ्करदेशिकाष्टकम् extolling his Guru’s grace.

Adi Shankaracharya granted sanyasa to Giri and gave him the name Totakacharya.
The story of how Giri became Totakacharya is a great example of the importance of faith and devotion in your Guru and not the mere knowledge of the Shastras.
@DetheEsha

1) Core attributes of a promising founder worth following:
- Progress/trajectory over time
- How well they lead a team &
- Make the vision happen
- Most impressed when someone is way ahead of where you thought they would be when you check up/see them a few months later.

2) Indie Makers have such a benefit of being small, fast, nimble workers in comparison to big companies.

We can easily pivot and vastly change a project of ours. We can change as we learn more about our users.

Big companies can take months/years for even the smallest of pivots.

3) Before you find a product market you can pivot your project as many times as necessary until you find something that works.

Then you only have one thing to do: scale, scale, scale.

4) Be obsessed with the little details.
- listen to every single person who uses your product
- reply to every single person who emails you about your product
- ask them what they like and do not like
- iterate your product, make changes, pivot if necessary

5) Paul Graham's (@paulg) name came up with a feeling of great admiration! Naturally! It was Paul who said:

In the early stages of a company just;
- write code
- talk/sell to customers to stress test your idea

Nothing else.

Samayapuram Mariamman Temple
#Trichy
#Tamilnadutemples 🚩

Samayapuram Mariamman Temple is located in Samayapuram of
 Tiruchirappalli district.  Mariyamman here is worshipped as Samayapurathal a form of Parashakti.
Amman vigraham here is made of sand and clay so

no abhishekam done to the main vigraham. Samayapuram Mariamman Temple is one of the famous Shakthi Sthal of Tamilnadu.

Story says that paramashiva created Kali, out of the poison that he drank during samudra mathanam.  As Devi originated from the Kaalakoota/ halahala poison,

thus the name Kaali. Mariamman is believed to be a form of Kaali, and is also known as Mahamayi. It is also believed that Maharaja Dasharatha offered his prayers here.

Mariamman is Parashakti herself who blesses with prosperity and she is believed to cure all diseases.

Paramashiva, Mahavishnu and Brahma Deva are believed to have taken blessings of Mariamman here.

Om Shakti Para Shakti
🙏🕉🙏

Dr. Anandibai Joshi

Upon her birth on 31 March 1865 she was named Yamuna, after the holy river. Her parents Gunputrao Amritaswar Joshee & Gungabai Joshee came from a long lineage of wealthy landlord family in Kalyan of Bombay Presidency, whose wealth was now waning.

Anandi was the sixth of 10 children, & had 4 brothers (only two of which survived) & five sisters. Her father was particularly fond of her, as she was a bright child with an inquisitive mind. Being an educated man himself, Ganpatrao assured that his daughter was taught Marathi.

As was common practice she was married at a tender age of 9, to Gopalrao Joshi, a 29 year old widower who worked as a postal clerk in the same city. After marriage her husband named her ‘Anandibai’ (which means ‘Joy of my heart’).

Gopalrao was man ahead of his times with reformist ideas & had married Anandibai on the condition that he would be allowed to educate his wife.

He even tried to enroll Anandi in a missionary school, but did not succeed. Despite being the supportive husband, Gopalrao had his flaws.

He was a strict teacher & would sometimes resort to beating if Anandi slacked in her studies.