I didn't have a picture handy to post today for my sleep-picture, so here's an old picture of when we brought in our recliner and Babby SCSI thought it was a fun new toy to climb on
so naturally she got into the box
It didn't work. She bit right through them
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In the spirit of @threadapalooza, here are all my tweets on building courses, all in one place with 1 line summaries
Continually updating...
Everything I know about how to create a transformational online course
Let's go 👇
1/ The thread that started it all, a collection of my essays and checklists on the
2/ There are two stages to building a successful online course business - launch and your first students
They require mastering different skill
3/ Avoid the same mistakes I made over the last 15 years doing this
4/ Great online courses are not about the transfer of knowledge
They're about the transformation of students
Continually updating...
Everything I know about how to create a transformational online course
Let's go 👇
1/ The thread that started it all, a collection of my essays and checklists on the
Do you have an online course?
— Andrew Barry \U0001f981 (@Bazzaruto) October 18, 2020
I want to tell you a little about learning architecture.
My agency partners with content experts to help them create courses, and I've written extensively about it.
If you want to learn about educational design, here's a start \U0001f447
2/ There are two stages to building a successful online course business - launch and your first students
They require mastering different skill
As my friend @BillyBroas pointed out to me last week: online courses are moving upmarket.
— Andrew Barry \U0001f981 (@Bazzaruto) October 28, 2020
What does this mean if you want to create an online course these days?
Think of it in two stages
3/ Avoid the same mistakes I made over the last 15 years doing this
Some of the mistakes I've made creating online courses make me cringe
— Andrew Barry \U0001f981 (@Bazzaruto) November 23, 2020
This coming week I'm going to share a few lessons I've learned from mistakes like these
4/ Great online courses are not about the transfer of knowledge
They're about the transformation of students
\u2018Education is the kindling of a flame, not the filling of a vessel.\u2019
— Andrew Barry \U0001f981 (@Bazzaruto) November 23, 2020
\u2013Socrates
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Keep dwelling on this:
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs