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Saved by @Alex1Powell

2020 marks the start of the quantum dot revolution.

 Completely ignoring the fact that "photocatalytic generation of reactive oxygen species (ROS) from quantum dots (QDs) has been widely reported."
Results: It was found that whereas singlet oxygen (1O2) was not produced by photoexcited QDs, superoxide anion(O2− )and hydroxyl radicals(OH) were generated by QDs, especially in the presence of a physiological concentration of electron donating agent including NADH.
Using cell metabolic activity assays and various probes of ROS generation, the formation of ROS in cellular environments was demonstrated.
Conclusion: Illumination of QD-treated cells and bacteria with light did affect viability. The above results, together with those of assays in the presence of various scavengers of specific ROS, indicate that the formation of ROS by QDs mainly proceeded via electron transfer.
Some electrons are directly transferred to O2 to generate reactive oxygen species (ROS) in the ETC.
... As signaling molecules, ROS play an important role in cell proliferation, hypoxia adaptation and cell fate determination, but excessive ROS can cause irreversible cell damage and even cell death.
Electron transfer is a process by which an electron moves from one atom or molecule to another. It is a key concept in redox chemistry – the chemistry of reactions where one reaction partner loses electrons (oxidation) while the other gains electrons (reduction).
Ferric means the iron atom has lost three electrons to form Fe+3, and ferrous means the iron atom has lost two electrons to form Fe+2. ... For example, ferric would be Fe(III) indicating Fe+3, and ferrous would be Fe(II) indicating Fe+2.
Iron(III) oxide-hydroxide or ferric oxyhydroxide is the chemical compound of iron, oxygen, and hydrogen with formula FeO. The compound is often encountered as one of its hydrates, FeO·nH ₂O [Rust].
Similar behavior is exhibited by some iron compounds, such as the ferrites and the mineral magnetite, a crystalline form of the mixed iron(II,III) oxide Fe3O4 (although the atomic-scale mechanism, ferrimagnetism, is somewhat different).
https://t.co/TPBtYuGPVR
So basically superparamagnetic piezoelectric crystalline nanoparticles dressed up as viruses do indeed cause oxidative stress related diseases.
Activated by light?

More from NotTheMacAnon

NotTheMacAnon
NotTheMacAnon
@NotTheMacAnon1
This nonspecific cation channel opens when illuminated with blue light, depolarizing the cell [4, 6] to trigger action potentials cells with high temporal precision [5]. Since the initial discovery of ChR2, many modifications have been made to refine the kinetic properties.

For example, ChETA, engineered to address limitations of spike fidelity with ChR2, has faster temporal kinetics and can maintain reliable spike precision up to 200 Hz [7].

Halorhodopsins (NpHR), light-gated chloride pumps activated by yellow light, allow for temporally specific hyperpolarization with single spike precision [8–10].

Archaerhodopsin-3 (Arch), a yellow light-activated outward proton pump, is an increasingly popular tool for light-induced hyperpolarization to inhibit cellular activity. Arch recovers spontaneously from inactivation with a much shorter recovery time than NpHRs [11].

Arch currents continue to increase with increasing light intensity, while NpHRs saturate [11]. The increased light sensitivity of the ArchT variant, along with better membrane targeting, allows for improved neural silencing both at cell bodies and terminals [12].
LIFE
NotTheMacAnon
NotTheMacAnon
@NotTheMacAnon1
👍🏻


https://t.co/0ywQ1y5NDj

Pott found an association between exposure to soot and a high incidence of scrotal skin cancer in chimney sweeps. This cancer is now known as Pott's or chimney sweep cancer.

Coal contains trace amounts of naturally-occurring radioactive elements. The process of burning coal at coal-fired power plants, called combustion, creates wastes that contain small amounts of naturally-occurring radioactive material (NORM).

Fly ash particles (a major component of coal ash) can become lodged in the deepest part of your lungs, where they trigger asthma, inflammation and immunological reactions.
SONG
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NotTheMacAnon
NotTheMacAnon
@NotTheMacAnon1
During a normal pregnancy, oxidative stress enhances antioxidant mechanisms that are capable of reacting by way of enzyme activity and non-enzyme free radical deactivators. However, pregnancy is also a state in which this adaptation and balance may be easily disrupted.

There is strong evidence that a chronicin flammatory reaction combined with the presence of a local oxidizing environment may play a vital role in the etiology and development of complications during pregnancy.

In late pregnancy, damage to DNA (especially when it is caused by oxidative stress) is associated with pre-eclampsia(PE), intrauterine growth restriction (IUGR), and the death of mothers in developing countries; it largely determines pregnancy – related susceptibility to diseases

The referential values of ROS and NOS and their minimal and safe concentrations or physiologically beneficial concentrations are yet to be determined.

The measurement of oxidative stress in vivo is perceived as controversial,

as the sen-sitivity and specificity of various oxidative stress markers is unknown.. .
HEALTH
NotTheMacAnon
NotTheMacAnon
@NotTheMacAnon1
Localized Surface Plasmon Resonance - an overview | ScienceDirect Topics

https://t.co/mzS7vVSREJ

https://t.co/353PdAX2fa

https://t.co/3yBImjOdd4

In some cases, almost 100% of the light energy can be converted to the second harmonic frequency. These cases typically involve intense pulsed laser beams passing through large crystals, and careful alignment to obtain phase matching.
SCIENCE
NotTheMacAnon
NotTheMacAnon
@NotTheMacAnon1
Transduction is the process by which foreign DNA is introduced into a cell by a virus or viral vector.

Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells.

Viruses have evolved?

specialized molecular mechanisms

to efficiently

transport their genomes

inside the cells they infect.

Delivery of genes, or other genetic material, by a vector is termed transduction and the infected cells are described as transduced.

A transducer is a device that converts energy from one form to another. Usually a transducer converts a signal in one form of energy to a signal in another.
HEALTH

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Harry Haury
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@letsthinkdeeply
@cain_nate My friend Nate Cain and I have worked hundreds of hours with various politicians and legal groups trying to explain the election laws and how they fit together. There are many misperceptions of what happened during this election and what it means.

Simply put, our election laws are an intricate tapestry designed to ensure accuracy and prevent fraud. They work together like parts of a car. But when certain parts fail, the car is just a hunk of scrap iron and plastic. In this case critical parts failed.
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You do not have to prove fraud or intent, you just have to show that the election officials were unable to conduct an election that met the law and relevant certification requirements. In this case, the election does not come close to meeting accuracy requirements.
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These specifications are found deep in laws like FISMA, HAVA, and state adoptions of EAC guidance. 1 ballot error out of 125,000 or 1 position read error out of 500,000. Just look at the discrepancies between incoming ballot counts and total votes, the system fails.
4/

It is worse in the the swing states in Democrat strongholds but it is bad in many places. You add the apparent losses of ballots through the Mail and error rates in the ‘system’ are staggering. Why do we have these rules? Sure it is to prevent fraud, but......
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Boz Tchividjian
@BozT
The evils committed by Ravi Zacharias were enabled by a toxic organizational leadership that is evidenced by how these same leaders responded when confronted about the widespread and ongoing abuses being perpetrated by the namesake of the institution. 1/29

Please take time to read this piece by @DavideAFrench and the 26-page letter written by a first-hand witness. Here are just some of the excerpts: 2/29

"At one point, Ravi suggested to me that the Task Force “issue a statement that they [the Thompsons] are hooligans, they are scoundrels, they are thugs, they are serial extortioners.” If we didn’t do that, he told me, he would ask his attorney to do so on his behalf." 3/29

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Evil Saint
Evil Saint
@sanctemalum
8 rules the top play by that those at the bottom should adopt.

— Thread
(requested by followers)

1. Leverage

Most poor people don't leverage. Trying to get everything done yourself will limit you to only how much you can do.

Get more hands working for you, and find a way to pay or show them what's in it for them.

2. Trust

When doing business, poor people would require collateral from strangers, but excuse those close to them because they *trust* them.

That's how you get scammed.

The unspoken rule is to know your safety net whenever you're not taking collateral.

Never need to trust.

3. Morality

Never seen a very successful businessman say "This is not a good thing, it's evil."

It's either good for business or bad for business. Its either effective or ineffective.

Morality will only limit you.

4. Reciprocity

Expecting someone to help you because you helped them in the past is ludicrous.

If you're no longer useful to them, people have no reason to help you.

"Whenever you see water flowing upstream it means someone it repaying a kindness."

— 48 Laws Of Power
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Rogier v Vlissingen
Rogier v Vlissingen
@vliscony
@jeffreyatucker In the end, it is all a natural consequence of a very human foible, namely that we all do everything we can to blame anybody or anything else for our problems, if we can get away with it. It's the reason why rulers start wars to squelch domestic dissent - macro and micro the same

The very notion of the germ theory of disease revolves around this and while it is good for selling medical interventions, treatments and pharmaceuticals, it is no good for either personal health, or public health in any way. We need to start looking at health on a holistic level

More of a systems approach to health would get us to see that the whole instinct to stamp out viruses, like the very counter-factual notion of "zero Covid," and other nonsense, are driven by this need to blame somebody or something else for our problems, so we can have our cake

and eat it too, i.e. we can pass the blame to others and go and kill them, be they bugs or other people (lockdowns???). The results are disastrous for health on both a personal and a public level, and we continue on a path of assured self-destruction. But times are changing, now.

Lifestyle Medicine @aclifemed provides the new paradigm, more of a systems approach to health, in which personal responsibility for our habits comes first, starting with nutrition. Immune systems become depressed by fatigue, stress, inner conflict, malnutrition and so on. Change
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Scott Hechinger
Scott Hechinger
@ScottHech
Every single public defender. Every single day.


Bail arguments, motions, oral arguments, hearings. Judges don’t know, follow, or care about the law. Prosecutors are willing to take advantage of it. And mandatory minimums, withheld evidence, & pretrial detention coerces people to plead before trial. When theres a jury. A shot.

But defenders still fight. And still win. Most times wins aren’t “Justice.” It’s power of repetition of argument in front of same judges. Introducing those in power to the people they oppress. Not just a RAP sheet or words on a page. Defenders make it harder to be brutal & cruel.

I worked as a public defender at an office as well resourced as any in the country. Social workers, team of investigators, a reentry team, support staff, specialist attorneys in immigration, housing, education, family. Relatively low caseloads (80-100). And yet still injustice.

Most think that balancing the scales of justice means more funding for defenders. Thats part of it. Enough a attorneys to actually be at bail hearings. Wrap around services to be able to help people trapped in the system end up better off in their communities. Lower caseloads.
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ArmaniTalks \U0001f399\U0001f525
ArmaniTalks 🎙🔥...
@ArmaniTalks
Your Most PRECIOUS Currencies:

-Energy

-Time

-Attention

-Trust

-Love

-Loyalty

-Respect

Only give these currencies to high value people. Never spend these currencies on low value shitheads eg: trolls, weasels, snakes, naysayers etc.

'Wait, I thought money was the most important currency?'

Nah.

Once you adopt abundance mentality, you realize their is no shortage of money.

Making the dollars your most important currency will have you leading an empty life.

Time to flip your perspective.

👇

▪Energy

When you strip yourself to the core, you are an emotional creature.

Emotions are your internal worlds energy.

Harnessing that energy is crucial for leveraging yourself to obtain whatever you want.

You have a finite amount everyday, so spend it wisely.

▪Time

A second that is lost will never be returned.

You start valuing the hell out of this currency the more you mature.

As the years start adding up, you realize time is precious.

You must always have a scarcity mindset towards time.

Once you do so, you will not be lazy.

▪Attention

You can be here, but not present.

Attention is completely mental.

Giving someone your attention means you are clearing up mental bandwidth to make room for them.

Only give your attention to people who help you grow.

For the negative ones?

Ignore their existence
LIFE
Jaya_Upadhyaya
Jaya_Upadhyaya
@Jayalko1
SRI SWETHA VINAYAGAR, THIRUVALANCHUZHI, KUMBAKONAM
(TN)
#bharatmandir

While main deity is Shiva as Kapartheeswarar, the kshetram is famous for Ganesha, known as Swetha/Vellai Vinayagar (white Vinayak)

During samudra manthan, Vasuki snake (used as rope) started spewing venom.


Unable to bear the intense heat, Devas rushed to Siva. He told them that this was because the task was started without getting Ganesha’s approval.
So the Devas created a Ganesha murti from white sea foam and worshipped it.
It was later taken by Indra to Indralok.
@GunduHuDuGa


But once Indra had to come to Earth to pray to Shiva to seek relief from a curse inflicted on him. So he brought the murti of Ganesha with him. When he came here, he wanted to take bath before puja. So he gave the murti to a boy to hold for sometime. The boy was actually Shiva.


He kept the murti down and vanished. Indra could not lift it again and a divine voice told him to let Vinayagar stay there and visit every Ganesh Chaturthi to pray.
Since Vinayagar is made of foam, no abhishekam is done here. Only punugu is applied n camphor powder is sprinkled
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Daoyu
Daoyu
@Daoyu15
@franciscodeasis https://t.co/OuQaBRFPu7
Unfortunately the "This work includes the identification of viral sequences in bat samples, and has resulted in the isolation of three bat SARS-related coronaviruses that are now used as reagents to test therapeutics and vaccines." were BEFORE the


chimeric infectious clone grants were there.https://t.co/DAArwFkz6v is in 2017, Rs4231.
https://t.co/UgXygDjYbW is in 2016, RsSHC014 and RsWIV16.
https://t.co/krO69CsJ94 is in 2013, RsWIV1. notice that this is before the beginning of the project

starting in 2016. Also remember that they told about only 3 isolates/live viruses. RsSHC014 is a live infectious clone that is just as alive as those other "Isolates".

P.D. somehow is able to use funds that he have yet recieved yet, and send results and sequences from late 2019 back in time into 2015,2013 and 2016!

https://t.co/4wC7k1Lh54 Ref 3: Why ALL your pangolin samples were PCR negative? to avoid deep sequencing and accidentally reveal Paguma Larvata and Oryctolagus Cuniculus?
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Jig's Patel
Jig's Patel
@jigspatel1988
What is best way to sell strangle in Banknifty on an intraday basis
Simple
at 9:45 Open Option chain and check In which strike highest OI change in call side and put side

Sell both option with combine SL
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Today 35000CE and 34500PE
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Hector Navarro
Hector Navarro
@Hectorisfunny
I'm going to attempt to chronologically list all of the Marvel characters Stan Lee had a hand in creating. Working with his genius collaborators, Stan and his team produced an insane amount of iconic characters in a roughy ten year period. (Thread)


With his younger brother, writer Larry Lieber, and Jack "the King" Kirby:

Groot

Tales to Astonish #13 (November, 1960)


With writer Lieber, and artist Kirby:

Fin Fang Foom

Strange Tales #89 (October, 1961)


With the King, Stan gives birth to the Marvel Universe:

The Fantastic Four

Fantastic Four #1 (November, 1961)


With Jack Kirby:

Mister Fantastic

Fantastic Four #1 (November, 1961)
CULTURE