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#IDTwitter #IDFellows
Introducing our new series: “IDFN top 10 articles every fellow should read”🔖

#1: SAB management
by @mmcclean1 @LeMiguelChavez
Reviewers @KaBourgi, @IgeGeorgeMD, @Courtcita, @MDdreamchaser

We know is subjective & expect feedback/future improvements 👇

 1. Clinical management of Staphylococcus aureus bacteremia: a review.
https://t.co/9tBCtp9mlP
👉 A must read written by Holland et al. where they review the evidence of the management of SAB.
2. Impact of Infectious Disease Consultation on Quality of Care, Mortality, and Length of Stay in Staphylococcus aureus Bacteremia: Results From a Large Multicenter Cohort Study.
https://t.co/XujO68pCuH
👉ID consult associated with reduced inpatient mortality.
3. Predicting Risk of Endocarditis Using a Clinical Tool (PREDICT): Scoring System to Guide Use of Echocardiography in the Management of Staphylococcus aureus Bacteremia
https://t.co/otcA1pxjAw
👉Predictive risk factors for infective endocarditis, and thus the need for TEE.
4. The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia.
https://t.co/CQZiryVWZz
👉Presence of cefazolin inoculum effect in the infecting isolate was associated with an increase 30-day mortality.
5. Cefazolin versus anti-staphylococcal penicillins for treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a narrative review.
https://t.co/mwaQ6Aw5vX
👉Similar outcomes for treatment of MSSA but more side effects with the anti-staphylococcal penicillins.
6. Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia.
https://t.co/Z7qxeZD8DM
👉Vancomycin had higher risk of treatment failure compared to cefazolin in MSSA BSI.
7. Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus.
https://t.co/9W1sYv3VR0
👉RCT: dapto noninferior to SOC (B-lactams or vanco + gentamicin). Dapto resistance can emerge on treatment and more renal dysfunction in the SOC arm.
8. Adjunctive rifampicin for Staphylococcus aureus bacteremia (ARREST): a multicenter, randomized, double-blind, placebo-controlled trial.
https://t.co/SWsKR78njJ
👉 Rifampin addition not different to standard therapy in failure, recurrence or death.
9. Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial. (CAMERA-2)
https://t.co/hNzJM4AOv5
👉more AKI with combination w/o benefit.
10. A Narrative Review of Early Oral Stepdown Therapy for the Treatment of Uncomplicated Staphylococcus aureus Bacteremia: Yay or Nay?
https://t.co/2ysr7lDYBW
👉 Oral step-down therapy can be an alternative in some select patients without complicated SAB.
Which article did we miss, or you would include in this list?
@BCMIDFellowship @DartmouthID @OhioState_ID @BIDMC_IDFellows @Tufs_ID @IUIDfellowship @UAB_ID @yaleIDfellows @ID_musc
@templeID1 @VUMC_IC @MayoclinicINFD @MGH_ID @UCLA_ID @MontefioreID @UNMC_ID @UVA_ID @OhioState_ID @UTSWinfDis @BrownIDprogram @RushCCH_ID @OHSU_ID
Also, check out this timeline of landmark trials.
Which trial would you like to add?
Next in "IDFN top 10 articles every fellow should read”:

- Infective Endocarditis 💙🦠

Coming soon: Osteoarticular infx , Enterobacterales infx, Transplant ID and more.

Check out the next tweet if you want to be an author of this series.
The IDFN is looking for content creators! Please retweet and share!

More from For later read

Jasnah Kholin - ACAB
Jasnah Kholin - ACAB
@wanderer_jasnah
*puts on hard hat, respirator, asbestos gloves* (hey i haven't used these in awhile!)

okay. i'm seeing the same claims on my TL over & over that quite frankly, make no sense. & now they're starting to broken-telephone into each other so:

my thoughts on vaccine schedule.

first off, let me get one thing across to start: this is not 2 doses v. 1 dose, it's 2 spaced 3-4 weeks apart vs. 2 spaced several months apart.

anyway, to begin: if you are reluctant to modify vaccine dosing schedule from the 3-weeks-apart one that we had in the Pfizer/BioNTech PhaseIII, *that's fine*. that's a legitimate reason.

but say just that. we know this works, we don't know about other regimes.

but for the love of all that is holy, please do not try to imply that this is a hard requirement, or optimal (imho, it likely isn't), or even *chosen for any reason other than being the shortest interval we could use to complete the PhIII ASAP*. that's it.

i'll be honest, i'm amazed 3 weeks *works*. it's shorter than *the shortest MINIMUM interval* for any other vaccine as scheduled according to, say, the CDC:
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Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193
Billy Bostickson 🏴👁&👁 ...
@BillyBostickson
@snip96581187 @Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen Clearly, because as I have been saying for 8 months now, DTRA and DARPA have been using Ecohealth and UC Davis to collect novel pathogens for gain of function work back in the USA. I have documented this in many threads which I will post here just to annoy everyone.

@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen


@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen


@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen


@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
ALL , FOR LATER READ
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Mike Dunford
Mike Dunford
@questauthority
Nonlawyer Explainer Thread: On Keeping One's Mouth Shut

It occurs to me that certain private-jet-flying seditionists who continue to yammer on Twitter about their DC excursions provide us with the opportunity to do a little hypo to explore the benefits of silence.

So let's explore what a hypothetical law enforcement interview *might* look like in this situation. I'm not - I want to make clear - drawing from experience as a lawyer here.

I AM NOT A CRIMINAL LAW ATTORNEY.

Instead, I'm mostly drawing from discussions with my father-in-law.

My father in law is a now-retired homicide cop, and we've had a lot of discussions (especially since I started law school) about criminals and interviews over the years.

So with that in mind, let's look at this hypo.

ALSO - Simplifying for Twitter character counts.

*Knock*
*Door opens*
Agent: Ms [Name]? I'm Agent Smith, and this is Agent Jones. We're with Agency. We'd like to talk to you if you've got a minute.

Ms X: Oh? Is this about that thing at the Capitol?

[Yes, it seems insane but if you're worried about something specific and the cops show up, blurting out something like that is totally a thing that can happen.]
FOR LATER READ
GAVNet
GAVNet
@GAValueNetwork
Daily Bookmarks to GAVNet 02/13/2021

Claudia Sahm on Twitter and ThreadReader

https://t.co/UNH4NEks6h

https://t.co/kFdktm5eeu

#UnemploymentBenefits #EconomicRecovery #StimulusChecks #PandemicResponse
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pete wolfendale
pete wolfendale
@deontologistics
My morning thought. I think what's most incompatible about the way I think and the journal article format as a means of capturing and validating thought is that I have a completely different sense of the relation between tentativeness, rigor, and informatic compression.

The characteristic Pete thought is: wait a minute, this whole area is dominated by an assumption that no one seems to be questioning, and I've got two options to express that: i) outline the logic of the issue in a quick and compressed way, ii) write a small book with references.

The discipline seems to want something in between these poles every single time, and this makes me extremely anxious because I feel (with good reason) like any partially referential engagement with the issue will get instantly torpedoed by anyone outside its referential remit.

To repeat something I've said before: I'm actually quite good at being *concise*, I just find it very hard to be *brief*, because most of the thoughts I have don't permit brevity. Consider what your (referential) reactions are to this brief piece:

One of the main genres of publication I've actually excelled in over the years is dictionary articles, which I take a lot of joy in writing, and include some of the pieces of which I'm most proud. Consider this one on the crux of Meillassoux's project:
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Melissa (she/her)
Melissa (she/her)
@LiteraryMouse
In regards to the #CapitolCoup, I’m in a unique position. I monitored forums ahead of time and then was present for the coup itself.

These are my observations based on what I saw and the evidence that’s been collected so far. I reserve the right to adjust my analysis as needed.

Let’s talk about the organization of the coup first. Seeing some people insist that the coup must have been highly planned and coordinated.

Yes and no. This was a #StochasticCoup. We’ll see little evidence of direct communication between Trump and the insurrectionists.

Within the insurrectionists, there was not one group that executed the storming of the Capitol.

Rather, there were a number of smaller groups working independently towards the same goal. I expect you’ll see little evidence that these various groups communicated with each other.

What you will see is detailed planning and coordination within these small groups.

Then there were the joyriders, those Trump supporters who weren’t directly involved in any plotting but who were more than happy to go along for the ride once the coup was in motion.

After four years, the insurrectionists were carefully attuned to Trump’s messaging.

Every tweet and statement of his was treated as marching orders and carefully dissected for meaning.

It’s why shutting down Trump’s Twitter account was so important.
POLITICS , INSURRECTIONISTS
\u0936\u094d\u0930\u0940\u092e\u093e\u0932\u0940 \u0939\u093f\u0924\u0947\u0936 \u0905\u0935\u0938\u094d\u0925\u0940
श्रीमाली हितेश अवस्थी...
@HiteshAwasthi89
#Thread
Lessor known facts of Sudarshan Chakra or Neela Chakra of Puri Jagannath Temple.

The metal wheel at the top of Bhagwan Jagannath temple is also known as Neela Chakra (Blue Wheel). The wheel is made of eight metals comprising of.. 1/n


iron, copper, zinc, mercury, lead, brass, silver & gold. It's circumferance is about 36 feet & it is so designed that there is a wheel within the wheel. The circumferance of the inner wheel is about 26 feet. Eight hubs join together the inner and the outer wheels. 2/n


There are decorative designs on the outer wheel. The thickness of the Neela Chakra is 2 inches.The wheel is said to be Bhagwan Vishnu's most powerful weapon, Sudarshana Chakra. Inside Jagannath temple, Lord Vishnu's wheel is also worshipped in the name of 'Sudarshana'. 3/n


But inside the temple Sudarshana is not in the shape of a wheel, but in the shape of a small wood pillar placed to the left of image of bhagwan Jagannath. It is believed that the same Sudarshana is also at the top of the temple and is known by the name of Neela Chakra. 4/n


There is a specific category of people among the temple sevaks to serve the Neela Chakra and they are known as Garuda Sevaka or Chunara Nejoga. The pilgrims hold these sevaks in high esteem because everyday at Sunset. 5/n
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Jaya_Upadhyaya
Jaya_Upadhyaya
@Jayalko1
DODDA GANAPATHI, BENGALURU
#karnatakatemples

Dodda in Kannada means big. Sri Ganesha here is 18 ft tall in height and 16 ft wide. Dodda Ganesha is also known as Shakthi Ganapathi and Satya Ganapathi.

It is said that Kempe Gowda, the founder of Bengaluru, saw a rock here.


The rock had engravings of Ganesha. His sculptors cut the Ganesha murti from that single rock. Later, a shrine was built around the Ganesh murti.

It is believed that Dodda Ganapathi is the protector of Bengaluru. All auspicious events start by praying to Him.


Benne Alankara is the most famous festival here when about 100 kg of butter is coated over Ganapathi every four years and the rich prasad is offered to the worshippers.

Ganesha is also covered in cream colour and is decorated with golden laces and buttons
@GampaSD


The Dodda Ganapathi murti is believed to be still growing in size, especially towards right.

The weavers from old Bengaluru tie a coconut to their looms before starting work. When the work is completed, they break 100 coconuts here along with the one tied on the loom.
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Dr Catherine Pemble is #SocialDistancing
Dr Catherine Pemble is...
@CatherinePemble
Right, screw it. Here's a thread on *that* FBLive by Alex Cairnie about #Govanhill. Lets do a watch-through shall we? (Mind, I'm a resident of Govanhill, and a sociologist. I'm also 5'3, and a visibly queer woman so if half his claims are true I should be living in terror)

00:30: Welcomes viewers and uses points out that his videos are only getting attention b/c they're 'horrific'. Directs folk to his Youtube page. So already clout hunting.

1:08: "I've been warned to stay out of Govanhill. I'm a marked man" (proceeds to use a beanie as a disguise)

1:30 "Laughing and joking aside, here's somebodys front garden." Proceeds to show litter and claim its thrown from windows and this is 'common'. I know a handful of streets with litter issues like this, but its neither common nor unique to #govanhill and other deprived areas.

2:10 "Don't be under any illusion I'm only showing you the bad bits" - only shows you the bad bits.

3:45: He's had offers of help, but hes said no because hes not responsible for 'anybody elses safety' Good lord.

5:01: "Its not that bad. But its not all good either" -Correct

6:00: TW: child abuse - He starts claiming to have been contacted by a health professional and told about child abuse 'in the area'. Huge ethical issues here as the 'professional' who has 'been in the game a long time' is reporting to Facebook Dude and not authorities.
HEALTH
Anu Satheesh \U0001f1ee\U0001f1f3
Anu Satheesh 🇮🇳...
@AnuSatheesh5
Nanganallur Anjaneya Temple
#Chennai
#Tamilnadutemples 🚩

Bhaktha Anjaneya temple at Nanganallur in Chennai is one among tallest Anjaneyar Vigraham. Here Anjaneyar blesses with relief to all illness. Vigraham is about 32 feet height made of single  stone.
Anjaneyar here is 👇


Sri Vishwaroopa Aadhivyathihara Baktha Anjaneya Swamy.

Sthala Puranam says that, this is the place where Indra Deva hit Hanuman on the cheek by his Vajrastram. Sri Raghavendra Swami and Sri Kanchi Paramacharyar were behind in building this temple. Temple is constructed to


Realize power of Anjaneyar who is seen both in Ramayana and Mahabharatha.
Vadamalai is important offering to Anjaneyar here. It is believed that vigraham contain powers to heal any disease. Shri Ramanavami is celebrated here.

Jai Sri Ram
Jai Hanuman
🙏🕉🙏
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