CodyyyGardner's Categories

CodyyyGardner's Authors

Latest Saves

EMPTY HOSPITALS IN THE UK...WHAT IS GOING ON?!!! #SCAMDEMIC2020


https://t.co/8amD9PQhfO


https://t.co/pmCsSJ6a1p


https://t.co/KRPpFVCSgz


https://t.co/9iyvqPyo9O
1/16
Why do B12 and folate deficiencies lead to HUGE red blood cells?

And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?

For answers, we'll have to go back a few billion years.


2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.

Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine

But why does DNA contains thymine (T) instead of uracil (U)?

https://t.co/XlxT6cLLXg


3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).

In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?

https://t.co/bIZGviHBUc


4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.

DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.

https://t.co/bIZGviHBUc


5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.

When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.

[*Note: thymine is the base in dTMP]

https://t.co/AnDUtKkbZh
Hi @chelwestft @EHRC @EHRCChair @KishwerFalkner @RJHilsenrath @trussliz @GEOgovuk

The Equal opportunities section in your job application mentions the Equality Act 2010 four times and correctly lists sex as a protected characteristic. However...

1/11


However, you then ask for the 'gender' of the applicant with options:

Male
Female.

2/11

'Gender' is not a protected characteristic under the Equality Act 2010 and is not defined in the Act.

https://t.co/qisFhCiV1u

3/11


Sex is the protected characteristic and the only two possible options for sex are 'Female' and 'Male' as defined in the Act and consistent with biology and there is no way to self-describe one's sex.

https://t.co/CEJ0gkr6nF

'Gender' is not a synonym for sex.

4/11


Asking about a personal characteristic such as 'gender' that is not a protected characteristic under the Act, may be in breach of the GDPR by processing personal - and potentially Special Category - data without a lawful basis.

5/11
@Collinstaxacct @RepSwalwell 1/ Istanka, Axe Murderer Barbie and her 🐀faced weasel bastard traitor Comrade Kushnerov (attempted a Kremlin back channel WHY?) pals with Rupert Murdoch's ex and Putin's reputed squeeze Wendi Deng, literally Chinese Intelligence Services, ignoranus.

@RepSwalwell 2/ Comrade Kushnerov, Istanka/Axe Murderer Barbie and Psycho Killer in Chief Trump in terms of their cheap, shabby, tawdry, sordid, rancid, hinky, skeezy, sleazy, scaggy, scumbag-y financial ties are more Chinese than a fortune cookie.

@RepSwalwell @anglicanrichard
3/


@RepSwalwell @anglicanrichard @Khanoisseur
@gdeguzman99 @FreeTheWH @TheNakedParty


@RepSwalwell @anglicanrichard @Khanoisseur @gdeguzman99 @FreeTheWH @TheNakedParty