Virus-Like Particles: Revolutionary Platforms for Developing Vaccines Against Emerging Infectious Diseases

In memoriam Nicola Bidoli

VLP applications characteristics challenges
VLP Induction of innate and adaptive immunological responses (A) humoral immunity; (B) cell-mediated immunity) by VLPs
VLPs Advantages and limitations of different expression systems for the development of virus-like particles.
VLP vaccines against different viruses and parasites.
VLP - how to produce them
Proposed production system and mechanism of action of SARS-CoV2 virus-like particle vaccine. Plasmids encoding the structural proteins (S, N, M, and E) of the SARS-CoV2 can be transfected into an appropriate mammalian cell line.

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