I’m 18, currently working on my own startup (TBA)
To all the founders out there...
What “startup advice” would you give yourself at 18?
The stuff nobody tells you
More from Startups
.@zapier built a $140M ARR business on $1.4M in VC that has become the logic layer of the no-code industry.
But it has the potential to be something even bigger: the Netflix of productivity.
Our report and a thread 👉
We believe @seqouia and @steadfast got a good deal buying into Zapier at $5B.
We value Zapier at $7B based on:
- 30-50% YoY growth over the next five years
- Zapier’s monopoly status in the solopreneur/SMB market
- 30-40% YoY growth of no-code TAM
No-code is huge and growing, but as @edavidpeterson has written, no-code is about more than tools: it’s about a philosophy that emphasizes interoperability and customizing your software to your needs.
https://t.co/UJY6BRtXwl
.@zapier enabled interoperability by building a solution to one of the intractable problems in SaaS: APIs that don’t talk to each other.
The product took off and hit $100M ARR in just 9 years, comparable to companies that have raised 100x as much money.
https://t.co/0Thk42eRpJ
Zapier was riding an explosion in APIs that started the same year they were founded—2011.
Suddenly, every SaaS business wanted to offer its users extensibility, but not spend time figuring out what integrations to build or building them.
That’s where Zapier came in handy.
But it has the potential to be something even bigger: the Netflix of productivity.
Our report and a thread 👉
We believe @seqouia and @steadfast got a good deal buying into Zapier at $5B.
We value Zapier at $7B based on:
- 30-50% YoY growth over the next five years
- Zapier’s monopoly status in the solopreneur/SMB market
- 30-40% YoY growth of no-code TAM
No-code is huge and growing, but as @edavidpeterson has written, no-code is about more than tools: it’s about a philosophy that emphasizes interoperability and customizing your software to your needs.
https://t.co/UJY6BRtXwl
![](https://pbs.twimg.com/media/ExRExdmWgAo7glk.jpg)
Trying this on for size\u2026
— David Peterson (@edavidpeterson) January 14, 2021
\u201cNo code\u201d isn\u2019t a coherent category. It\u2019s a design philosophy.
But tools built with this philosophy in mind will be the biggest winners of the next decade.
Let me explain what I mean by way of analogy.
.@zapier enabled interoperability by building a solution to one of the intractable problems in SaaS: APIs that don’t talk to each other.
The product took off and hit $100M ARR in just 9 years, comparable to companies that have raised 100x as much money.
https://t.co/0Thk42eRpJ
![](https://pbs.twimg.com/media/ExRE5RfWYAsUba4.png)
Ever notice that Zapier is doing $100m+ and has no direct competition? Found their niche and crushed it \U0001f44c
— Tyler Tringas (@tylertringas) November 7, 2019
Zapier was riding an explosion in APIs that started the same year they were founded—2011.
Suddenly, every SaaS business wanted to offer its users extensibility, but not spend time figuring out what integrations to build or building them.
That’s where Zapier came in handy.
![](https://pbs.twimg.com/media/ExRFPoUW8AMOsZ6.jpg)
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Keep dwelling on this:
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
![](https://pbs.twimg.com/media/Ew0HvalUYAYijlY.png)
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
![](https://pbs.twimg.com/media/Ew0MGQlVoAYB2ZO.png)
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
![](https://pbs.twimg.com/media/Ew0MumbUcAMRHTO.jpg)