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A thread (a mostly apocryphal yet would love to believe in story) on John Bart King: Greatest of all American cricketers. (Yes, they did played cricket during late 1800s to early 1900s)
Story from @Ram_Guha edited book, 'The Picador book of Cricket'
#Cricket
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![](https://pbs.twimg.com/media/EsBZ1jtXYAcLA3k.jpg)
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‘For heaven’s sake,’ he demanded, ‘you said you didn’t want a wicketkeeper, but what do you want him for?’
‘He’s not a wicketkeeper,’ said King. ‘He’s not even a fielder.’
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‘I’ve given the umpires enough trouble already,’ said King. ‘He’s there to pick up the bails.’
King, so the story goes, then ran up and hit the stumps with a fast ‘angler’. The fieldsman bent down & gathered up the bails, which had fallen at his feet.
End
🙌😅
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Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
![](https://pbs.twimg.com/media/Ew0HvalUYAYijlY.png)
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
![](https://pbs.twimg.com/media/Ew0MGQlVoAYB2ZO.png)
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
![](https://pbs.twimg.com/media/Ew0MumbUcAMRHTO.jpg)