BC SOCIETY
Saved by @Jacobtldr

How long should trans females be made to reduce their levels of circulating testosterone should prior to competing in the women competition?

 Gooren found that during the first 12 months muscle mass (area) was decreased by 9.4% & hemoglobin levels by 14% in 20 transwomen (M2F trans) treated with an estrogen-based regimen that reduced circulating T concentrations from the male range to the female range.
Conversely, in 17 transmen (F2M transgender) treated for the first time with testosterone for 12 months (which increased circulating testosterone levels to a mean of 31 nmol/L), muscle mass increased by 19.2% and hemoglobin by 15%.
https://t.co/MOZtfh5Raf
The muscle mass findings remained stable between 1 and 3 years after initiation of treatment, although fat mass continued to change between 1 & 3 years of T treatment. although with disproportionately greater effect on muscle strength than on muscle mass.
https://t.co/8rMfUi4brV
This study did not report muscle strength, but other studies of T dose-response relationships for muscle mass and strength show consistently positively correlation,

https://t.co/0SqyneBjPZ…

https://t.co/pgyggiNG2u

https://t.co/0SqyneBjPZ…

https://t.co/A5AVkkShDj
Hence, the muscle mass estimates in these prospective treatment initiation studies in trans individuals likely underestimate the muscle strength gains from...
Elevated T levels where the circulating T markedly exceeds female range to be within the male range as occurs in severe hyperandrogenism of DSD females, poorly controlled transwomen (M2F transgender),..
or transmen (F2M transgender). These effects are also the biological basis of the ergogenic efficacy of androgen doping in women.
In both intersex/DSD and trans individuals, the developmental effects of adult male circulating T concentrations will have established the sex difference in muscle, hemoglobin, & bone, some of which is fixed & irreversible (bone size)....
.& some of which is maintained by the male circulating testosterone concentrations (muscle, hemoglobin).
The limited available prospective evidence from initiation of trans cross-sex hormone treatment suggests that the advantageous increases in muscle & hemoglobin due to male circulating T concentrations....
...are induced or reversed during the first 12mths & the androgenic effects may plateau after time.
This time course is much faster than the somatic effects of male puberty, which evolve over years and for some variables (e.g., peak bone mass) are not complete for up to a decade after the start of puberty.
However, the abrupt hormonal changes induced by medical treatment in intersex/DSD or transgender individuals may be telescoped compared with male puberty where circulating testosterone concentrations increase irregularly and incompletely for some years.
Additional data are available from the unique investigative model of men undergoing castration for prostate cancer. Just as androgen sensitivity to testosterone may differ between tissues...
https://t.co/S2yyg9Xq8j
The time course of offset of androgen effects following withdrawal of male testosterone concentrations may also differ between the major androgen-responsive tissues.
For example, circulating hemoglobin shows a progressive fall for 6 months reaching a nadir and plateau at 12 to 16 months in six studies involving 534 men undergoing medical castration for prostate cancer.
https://t.co/Bcg0PuNNu3
Although these studies of older men with prostate cancer must be extrapolated with caution, age, stage of disease, race, & baseline circulating T concentration did not affect the rate or extent of decline in hemoglobin.
https://t.co/Bcg0PuNNu3

https://t.co/2bii5lMZYy
Comparable longitudinal studies of muscle loss, strength, and performance following castration for prostate cancer are well summarized,
https://t.co/olda0NryXA
Showing progressive loss for 24 months (see Fig. 4).
Further clinical studies to define the time course of changes, mainly offset, in testosterone-dependent effects, notably on muscle and hemoglobin, are badly needed to determine the optimal duration for cross-sex hormone effects in sports.

End
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Would having the testosterone limit for transgender women at 10nmol/L (5-10 times what’s considered “typical” for women) give them a massive advantage over their cisgender opponents?


Absolutely not, is recognized an XY chromosome body is seen as unhealthy <12nmol/L or less. A XY female as they lose the ability to produce natural occurring testosterone, falls into a range of 0.4nmol/L.

Which we know too, the individual falls into menopause at 9.6nmol/L, and due to complete androgen deprivation eventually into the position of that would equate a XX female = who had had a complete hysterectomy including her gonads.

We can be assured, one this is extremely unhealthy – Moreover, and most important, we can be assured that there are no women either XX and or XY competing internationally like this.

This is not for anyone a desired state and for the participation high performance sport eventually impossible to participate longterm.
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It was 800 metres finals day, but to my surprise, there were 5 races scheduled, not two.
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On inquiring, I learnt there had been a shake-up: the "men's" and "women's" classifications were no more; instead the classification system changed to one that was based on functional ability.
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Rather than labelling athletes as male or female , they were placed in a racing category based on the movements their body can perform, related to the sport they compete in.

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Finding the balance between sex, gender, human rights,  & the sciences and fairness in sport is without a doubt sports greatest challenge.

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Kirsti Miller
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I have a passion to help &  educate other trans athletes about their own bodies. I suffer many adverse health conditions from not understanding my own post surgery endocrine system early enough before it had damaged my health.
1-

This article shows the consequences to health when trans girls experience low T. This is important to educate everyone because in this conversation those against us compare men's performance versus women.
2-


This article also shows trans girls have very different endocrine systems to a healthy male and as such they should not be compared to men when talking about sports

The only comparison you can make between a trans female athlete and a male would be to compare the trans girl to a male that has either been surgically or chemically sterilized.
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You won't even find men competing in elite sports in this health state without being prescribed T replacement therapy which is not available to a trans woman like me in sports.
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Kirsti Miller
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Hopefully it gets pulled down like the statues of dubious heroes of oppression from an earlier age.


@ScottMorrisonMP The two-party-preferred system in 
Australia politics isn’t working for people, and it sure isn’t working for the planet.

@ScottMorrisonMP My collapse of faith in our democracies isn’t an accident. It’s one of the central victories of the neoliberal project, delivered through two generations of privatisation, outsourcing and deregulation, underfunding of government services (locked in by tax cuts),...

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