1) Masks get saturated by large "respiratory droplets" containing viral molecules. Air turbulence against trapped droplets may create aerosols that eventually diffuse around edges. Continued...
COVID Masks: Mechanistic View: Part 2: Fine Aerosol Emissions:
Masks may increase fine aerosol emissions from: 1) nebulization of large droplets into fine aerosols, or 2) friability of certain mask materials creating "aerosolized fomites."
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Here are the studies:
1) Masks get saturated by large "respiratory droplets" containing viral molecules. Air turbulence against trapped droplets may create aerosols that eventually diffuse around edges. Continued...
Study: Ha'eri 1980
Title: The efficacy of standard surgical face masks: an investigation using "tracer particles"
Albumin tracer particles put inside a surgical mask were dispersed into the room by breathing.
https://t.co/Ll5CfBPVj6
Study: Liu 2020
Title: Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals.
SARS-2-COV sub-micrometer aerosols not tightly bound to surfaces, get airborne when PPE is taken off.
https://t.co/GK9SeOwgcj
https://t.co/qlzLK1N1Aw
Do our masks stop large droplets or do they nebulize them into Aerosols? From my emulsion days, best way to get a monodispersed emulsion is to force H20 through a pore sized membrane that has a different phase (oil or air) on the other side of it. https://t.co/Y9UCmWZ7uT pic.twitter.com/bGZBxI6lUT
— Kevin McKernan \U0001f642 (@Kevin_McKernan) October 24, 2020
2) "Aerosolized fomites" from the mask material itself (e.g. cotton or fabric) are shed during breathing. These tiny organic particles - fomites - are contaminated by even smaller viral molecules.
Friability of mask materials: Cotton or fabric may emit fine particles < 1 um, possibly spreading viral contamination. This study found breathing through DIY masks of cotton or fabric increased forward emission of fine aerosols.
https://t.co/nks9rCb6Ox
Cotton or cloth releases tiny organic material - aerosolized fomites - that can potentially serve as a conduit for viral molecules.
Limitations:
Only measured 2 minutes of emissions
Only measured forward emissions; not emissions around edges; may underestimate total emissions vs no mask
Could not tell if medical-grade masks also increased aerosols when fully contaminated with droplets
Title: Influenza A virus is transmissible via aerosolized fomites
Found that non-respiratory "aerosolized fomites" (organic debris) contaminated with a virus can infect other animals. May play large role in viral transmission.
https://t.co/p3lRxeqOiA
So masks might capture some viral debris, but emissions might be in a more easily transported aerosol.
It's analogous to someone mistakenly power sanding lead paint to remove it. The total amount is reduced, but remaining portion is in a more hazardous form.
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Why is this the most powerful question you can ask when attempting to reach an agreement with another human being or organization?
A thread, co-written by @deanmbrody:
2/ First, “X” could be lots of things. Examples: What would need to be true for you to
- “Feel it's in our best interest for me to be CMO"
- “Feel that we’re in a good place as a company”
- “Feel that we’re on the same page”
- “Feel that we both got what we wanted from this deal
3/ Normally, we aren’t that direct. Example from startup/VC land:
Founders leave VC meetings thinking that every VC will invest, but they rarely do.
Worse over, the founders don’t know what they need to do in order to be fundable.
4/ So why should you ask the magic Q?
To get clarity.
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Multiple responses to this question are likely to deliver a positive result.
Why is this the most powerful question you can ask when attempting to reach an agreement with another human being or organization?
A thread, co-written by @deanmbrody:
Next level tactic when closing a sale, candidate, or investment:
— Erik Torenberg (@eriktorenberg) February 27, 2018
Ask: \u201cWhat needs to be true for you to be all in?\u201d
You'll usually get an explicit answer that you might not get otherwise. It also holds them accountable once the thing they need becomes true.
2/ First, “X” could be lots of things. Examples: What would need to be true for you to
- “Feel it's in our best interest for me to be CMO"
- “Feel that we’re in a good place as a company”
- “Feel that we’re on the same page”
- “Feel that we both got what we wanted from this deal
3/ Normally, we aren’t that direct. Example from startup/VC land:
Founders leave VC meetings thinking that every VC will invest, but they rarely do.
Worse over, the founders don’t know what they need to do in order to be fundable.
4/ So why should you ask the magic Q?
To get clarity.
You want to know where you stand, and what it takes to get what you want in a way that also gets them what they want.
It also holds them (mentally) accountable once the thing they need becomes true.
5/ Staying in the context of soliciting investors, the question is “what would need to be true for you to want to invest (or partner with us on this journey, etc)?”
Multiple responses to this question are likely to deliver a positive result.