Standard deviation should be ~average/3 maybe, so distribution spreads as you age and accumulate projects and get better at them.
I’m guessing these responses really reflect people’s weighted averages (age*current average effort fraction) though I kept it simple and asked for just averages.
Poll: where is the temporal center of gravity of all your live projects based on average age of start-dates?
— Venkatesh Rao (@vgr) January 17, 2021
Standard deviation should be ~average/3 maybe, so distribution spreads as you age and accumulate projects and get better at them.
No point learning food follow through until you’ve found a few good starts to bet on. No point getting good at finishing until a few projects have aged gracefully.
Second oldest is ribbonfarm at 13 years old.
Then sparring-style consulting-fu, 10 years old.
Breaking smart, 6 years old.
My portfolio is getting long in the tooth
This sounds like yet another sermon about long-term thinking, but it isn't. It's a sermon about long-term *commitment.* It doesn't take much upfront thinking. I mean, fairly dim people seem to get married at 22 without much thought and make a successful 30-40 marriage out of it.
— Venkatesh Rao (@vgr) January 15, 2021
More from Venkatesh Rao
So, yesterday my daughter (9) was hungry and I was doing a jigsaw puzzle so I said over my shoulder \u201cmake some baked beans.\u201d She said, \u201cHow?\u201d like all kids do when they want YOU to do it, so I said, \u201cOpen a can and put it in pot.\u201d She brought me the can and said \u201cOpen it how?\u201d
— john roderick (@johnroderick) January 2, 2021
This is why I never wanted kids. Way too much responsibility for another human’s development. Depending on the child, this might either be the day they discovered who they were or the day that traumatized them into a lifelong fuckup. Either way I don’t want to direct the show.
As far as the can opener goes, it wouldn’t even occur to me to try and turn it into a teachable moment. That sounds vaguely quixotic. I’d just show them how immediately. I think my default is to try and instruct clearly but not demonstrate unless the person is truly disoriented.
I think there’s basically a right answer here: show the kid. If the kid has the aptitude they’ll enjoy the mechanism so much they’ll develop the figure-it-out skill with other devices. If not, it’s a training data point that will build remedial levels of intuition more slowly.
I think perseverance is both misframed and over-rated as a virtue. Misframed as in: everybody has potential for it in some areas and lacks it in others. Aptitude is those areas where perseverance comes easily to you. Meta-skill of knowing where/why you persist is more important.
One other thing I should really clarify and that the @nytimes piece got *severely* wrong: while I believe there are very strong sociological and even causal links between rationalism and NRx (especially in the Silicon Valley homes bases) their ideological and methodological
— (((E. Glen Weyl))) (@glenweyl) February 14, 2021
IMO trying to correct whatever the NYT writer thought he knew/understood is futile. "Willing to be misunderstood by the NYT" should be the default stance unless you want to waste a lot of time correcting an obsolete 2013 map for people who don't care.
The thing is, the NYT still has enough normative cultural power, even as it has fallen from newspaper-of-record, that it takes a particular sort of heretical self-confidence to sort of ignore whatever they happen to be wrong about on any given week, whether or not it concerns you
A subtle shift has occurred in the workings of the Gell-Mann amnesia effect. It used to be an individual private amnesia re: media ("I'll believe myself when I am certain they got it wrong because I'm an expert, but still believe them when I am not"). Now it's a collective effect
A sort of common-knowledge threshold has been crossed lately. "Everybody knows that everybody knows the NYT is wrong on X across largish subcultures." It's no longer mutual beliefs being validated occasionally 1:1.
More from For later read
https://t.co/w7koHyMJjL
The article mentions a “10 nucleotide linker” (GCAUAUGACU) in the poly-A tail. This is described in the patent link below (Modification of RNA, producing an increased transcript stability and translation
Here is a link to the full mRNA code if you wish to download it, blast it or make up a batch in your garage
The mRNA sequences used for Moderna mRNA-1273 & Pfizer BNT162b2 mRNA vaccines for COVID-19 (Direct link in Word Format). WHO International Nonproprietary Name Program # 11889 "Messenger RNA encoding the full-length SARS-CoV-2 spike glycoprotein"https://t.co/zTb7B0Apic pic.twitter.com/8tZxAZWI5S
— Roland Baker (@RolandBakerIII) December 24, 2020
An overview of the encoded spike
Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD and this includes the NTD (blue in monomer, dark gray in trimer attached to antibodies). AA 64, 66, 187, 213, 214 red. pic.twitter.com/4MX1ByAsrR
— Roland Baker (@RolandBakerIII) December 19, 2020
Initial mouse
News: NIH-Moderna investigational COVID-19 vaccine shows promise in mouse studies https://t.co/7JYuUyZT45
— NIH (@NIH) August 5, 2020
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Here's the most useful #Factualist comparison pages #Thread 🧵
![](https://pbs.twimg.com/media/FUBsXImUAAAERYq.jpg)
What is the difference between “pseudonym” and “stage name?”
Pseudonym means “a fictitious name (more literally, a false name), as those used by writers and movie stars,” while stage name is “the pseudonym of an entertainer.”
https://t.co/hT5XPkTepy #english #wiki #wikidiff
People also found this comparison helpful:
Alias #versus Stage Name: What’s the difference?
Alias means “another name; an assumed name,” while stage name means “the pseudonym of an entertainer.”
https://t.co/Kf7uVKekMd #Etymology #words
Another common #question:
What is the difference between “alias” and “pseudonym?”
As nouns alias means “another name; an assumed name,” while pseudonym means “a fictitious name (more literally, a false name), as those used by writers and movie
Here is a very basic #comparison: "Name versus Stage Name"
As #nouns, the difference is that name means “any nounal word or phrase which indicates a particular person, place, class, or thing,” but stage name means “the pseudonym of an