Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD. This is a plain English Description of the code:
https://t.co/w7koHyMJjL

The article mentions a “10 nucleotide linker” (GCAUAUGACU) in the poly-A tail. This is described in the patent link below (Modification of RNA, producing an increased transcript stability and translation efficiency)
https://t.co/pC8nynqjNv
Here is a link to the full mRNA code if you wish to download it, blast it or make up a batch in your garage lab:
https://t.co/SrTUKYleGn
An overview of the encoded spike protein:
https://t.co/4hSPjnwd6m
Initial mouse studies:
https://t.co/6WwNBrkIU6
The Pfizer-BioNTech vaccine’s brand name is now Comirnaty. koe mir' na tee
https://t.co/aITEWhBnaH
The backstory on mRNA vaccines:
https://t.co/t8kY76pbQc
More History:
https://t.co/R4dvvSofB2
Understanding optimized Modulation of untranslated regions (UTRs):
https://t.co/RttDHCO11j
Understanding codon optimization and why we prefer G & C
https://t.co/NQ3W2RaV3Z

More from For later read

Today's Twitter threads (a Twitter thread).

Inside: Planet Money on HP's myriad ripoffs; Strength in numbers; and more!

Archived at: https://t.co/esjoT3u5Gr

#Pluralistic

1/


On Feb 22, I'm delivering a keynote address for the NISO Plus conference, "The day of the comet: what trustbusting means for digital manipulation."

https://t.co/Z84xicXhGg

2/


Planet Money on HP's myriad ripoffs: Ink-stained wretches of the world, unite!

https://t.co/k5ASdVUrC2

3/


Strength in numbers: The crisis in accounting.

https://t.co/DjfAfHWpNN

4/


#15yrsago Bad Samaritan family won’t return found expensive camera https://t.co/Rn9E5R1gtV

#10yrsago What does Libyan revolution mean for https://t.co/Jz28qHVhrV? https://t.co/dN1e4MxU4r

5/

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"I lied about my basic beliefs in order to keep a prestigious job. Now that it will be zero-cost to me, I have a few things to say."


We know that elite institutions like the one Flier was in (partial) charge of rely on irrelevant status markers like private school education, whiteness, legacy, and ability to charm an old white guy at an interview.

Harvard's discriminatory policies are becoming increasingly well known, across the political spectrum (see, e.g., the recent lawsuit on discrimination against East Asian applications.)

It's refreshing to hear a senior administrator admits to personally opposing policies that attempt to remedy these basic flaws. These are flaws that harm his institution's ability to do cutting-edge research and to serve the public.

Harvard is being eclipsed by institutions that have different ideas about how to run a 21st Century institution. Stanford, for one; the UC system; the "public Ivys".