#SuvenLife – Niche R&D play..very high risk and very high reward…key is right allocation…
Jazz Pharma was quoting around $0.5 in 2009, today its $150 and Mcap of $8.5 Bn on Nasdaq..almost 300x in 11 years. 80% of its total sales ($2.1 Bn) come from single drug Xyrem.
This is R&D for New Chemical Entity (NCE)…very high risk and very high reward…
Brain-related illnesses, also known as CNS diseases, afflict more than 2 billion people worldwide. Diseases of the brain and mind range
SUVN-502 has recently failed in phase-2 trials where it couldn’t meet the primary end points related to Alzheimer’s but sub group studies has revealed some interesting statistically significant and
potentially beneficial effects of masupirdine on cognition,
of behavioural and psychological symptoms of dementia (BPSD). Market size for this could be $2 Bn for USA.
This molecule addresses a rare disease – Excessive Daytime Sleepiness (EDS) – in narcoleptic patients
3. SUVN-D4010 (phase-1 completed)
This molecule works for better cognition and as an anti-depressant
It addresses the biggest limitations of current major depressive disorder (MDD) therapeutics with rapid onset of action, no sexual dysfunction, and enhancement in cognition
Some of the listed companies on NASDAQ working in CNS, (though not
More from jeevan patwa
More from For later read
Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD. This is a plain English Description of the code:
https://t.co/w7koHyMJjL
The article mentions a “10 nucleotide linker” (GCAUAUGACU) in the poly-A tail. This is described in the patent link below (Modification of RNA, producing an increased transcript stability and translation
Here is a link to the full mRNA code if you wish to download it, blast it or make up a batch in your garage
An overview of the encoded spike
Initial mouse
https://t.co/w7koHyMJjL
The article mentions a “10 nucleotide linker” (GCAUAUGACU) in the poly-A tail. This is described in the patent link below (Modification of RNA, producing an increased transcript stability and translation
Here is a link to the full mRNA code if you wish to download it, blast it or make up a batch in your garage
The mRNA sequences used for Moderna mRNA-1273 & Pfizer BNT162b2 mRNA vaccines for COVID-19 (Direct link in Word Format). WHO International Nonproprietary Name Program # 11889 "Messenger RNA encoding the full-length SARS-CoV-2 spike glycoprotein"https://t.co/zTb7B0Apic pic.twitter.com/8tZxAZWI5S
— Roland Baker (@RolandBakerIII) December 24, 2020
An overview of the encoded spike
Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD and this includes the NTD (blue in monomer, dark gray in trimer attached to antibodies). AA 64, 66, 187, 213, 214 red. pic.twitter.com/4MX1ByAsrR
— Roland Baker (@RolandBakerIII) December 19, 2020
Initial mouse
News: NIH-Moderna investigational COVID-19 vaccine shows promise in mouse studies https://t.co/7JYuUyZT45
— NIH (@NIH) August 5, 2020
You May Also Like
The Eye of Horus. 1/*
I believe that @ripple_crippler and @looP_rM311_7211 are the same person. I know, nobody believes that. 2/*
Today I want to prove that Mr Pool smile faces mean XRP and price increase. In Ripple_Crippler, previous to Mr Pool existence, smile faces were frequent. They were very similar to the ones Mr Pool posts. The eyes also were usually a couple of "x", in fact, XRP logo. 3/*
The smile XRP-eyed face also appears related to the Moon. XRP going to the Moon. 4/*
And smile XRP-eyed faces also appear related to Egypt. In particular, to the Eye of Horus. https://t.co/i4rRzuQ0gZ 5/*

I believe that @ripple_crippler and @looP_rM311_7211 are the same person. I know, nobody believes that. 2/*
Today I want to prove that Mr Pool smile faces mean XRP and price increase. In Ripple_Crippler, previous to Mr Pool existence, smile faces were frequent. They were very similar to the ones Mr Pool posts. The eyes also were usually a couple of "x", in fact, XRP logo. 3/*

The smile XRP-eyed face also appears related to the Moon. XRP going to the Moon. 4/*

And smile XRP-eyed faces also appear related to Egypt. In particular, to the Eye of Horus. https://t.co/i4rRzuQ0gZ 5/*
