I've worked on a mAb and i will happily admit i didn't get the details! 1/
@PaoloWalnuts I looked into this as I was very surprised and thought it could be quite dangerous to go against the trial design.
I learnt a lot while i was doing it! There are a lot of misunderstandings and quite a few counterintuitive bits as well.
Thread...
I've worked on a mAb and i will happily admit i didn't get the details! 1/
I know how limited pfizer are in what they can claim. If they don't have data to prove something they can't claim it, even if it *really* is obvious. They have data on 21 days so they either stay quiet or they say the data support 21dy interval. 5/
So, why choose 21 days? 7/
21 days should long enough to work but quick enough to get data 9/
I'll try to hunt out the threads i came across. 10/
I also think it's been poorly communicated though. I understand why - in many ways JVCI, SAGE, MHRA et al have a lot to worry about right now! 12/
Clearly, in this case, giving everybody 1 dose will provide much more protecting and save very many lives.
*I'm coming on to this... 14/
15/
The numbers are skewed by all the pts who were infected before they were given the vx, or in the 7-14 days after it was administered. The fact that those folks get covid doesn't tell us how effective the vx is (just how long it takes to start working). So? 16/
We don't need to worry about the vaccine being effective after 1 dose. It is, stunningly so. 17/
https://t.co/5nw32LPiEk
What it suggests to me is that the projections for January and February must be properly frightening.
— Chris McQuillan (@ChrisMcQuilla13) January 1, 2021
https://t.co/WkD6pFZVbz
@Sandyddouglas
This issue is, appropriately, contentious. As a vaccinologist - & citizen & relative of people in at-risk groups - I fully support the UK decision to increase dose intervals of both our Ox/AZ product and the Pfizer product. I'd happily receive either with a >8w gap. Here's why \U0001f9f5 https://t.co/PZaxgGJUj4
— Sandy Douglas (@sandyddouglas) January 1, 2021
https://t.co/U3OEnGOrpw
Like me, \u2066@petermbenglish\u2069 changed his mind about the one v two vaccine dose controversy. He blogs why here. https://t.co/W8I5cm7LAk
— Trisha Greenhalgh \U0001f637 #RejoinEU (@trishgreenhalgh) January 2, 2021
More from Design
A person who adamantly argues for why you are powerless and takes offense at your self-determination could not be more clear about what role they prefer you in.
— Salom\xe9 Sibonex (@SalomeSibonex) December 30, 2020
Around 2012, while on summer break from what I felt was a lackluster school year, I was kind of at a breaking point. A prominent designer was peddling this self-help program, a $6000 weeklong workshop that centered around dinner with him and his influential friends.
His response to a fan who was deeply inspired by him and wanted to be a better designer, who asked "what if I can't afford the $6000?" was "You simply don't *want* to afford it." It's not a priority for you. I remember seeing it on Facebook and getting up from my chair.
It was gross, and it felt like the latest incident in what seemed like a long generational road of manipulating impressionable young people into thinking that the only thing stopping them from having the lives of these visible figures was passion
It felt wrong. Absolutely wrong. I thought about my best friend from high school. Someone just as—if not more—talented than me in art. Both of us dreamed of going to the same art school. Only one of us did. His familial socioeconomics as his undocumented status made it impossible
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These setups I found from the following 4 accounts:
1. @Pathik_Trader
2. @sourabhsiso19
3. @ITRADE191
4. @DillikiBiili
Share for the benefit of everyone.
Here are the setups from @Pathik_Trader Sir first.
1. Open Drive (Intraday Setup explained)
#OpenDrive#intradaySetup
— Pathik (@Pathik_Trader) April 16, 2019
Sharing one high probability trending setup for intraday.
Few conditions needs to be met
1. Opening should be above/below previous day high/low for buy/sell setup.
2. Open=low (for buy)
Open=high (for sell)
(1/n)
Bactesting results of Open Drive
Already explained strategy of #opendrive
— Pathik (@Pathik_Trader) May 27, 2020
Backtested results in 30 stocks and nifty, banknifty.
Success ratio : approx 40-45%
RR average 1:2
Entry as per strategy
Stoploss = Open level
Exit 3:15 PM Or SL
39 months 14 months -ve, 25 +ve
Yearly all 4 years +ve performance. pic.twitter.com/nGqhzMKGVy
2. Two Price Action setups to get good long side trade for intraday.
1. PDC Acts as Support
2. PDH Acts as
So today we will discuss two more price action setups to get good long side trade for intraday.
— Pathik (@Pathik_Trader) June 20, 2020
1. PDC Acts as Support
2. PDH Acts as Support
Example of PDC/PDH Setup given
#nifty
— Pathik (@Pathik_Trader) June 23, 2020
This is how it created long setup by taking support at PDC.
hopefully shared setup on last weekend helped. pic.twitter.com/2mduSUpMn5
Imagine for a moment the most obscurantist, jargon-filled, po-mo article the politically correct academy might produce. Pure SJW nonsense. Got it? Chances are you're imagining something like the infamous "Feminist Glaciology" article from a few years back.https://t.co/NRaWNREBvR pic.twitter.com/qtSFBYY80S
— Jeffrey Sachs (@JeffreyASachs) October 13, 2018
The article is, at heart, deeply weird, even essentialist. Here, for example, is the claim that proposing climate engineering is a "man" thing. Also a "man" thing: attempting to get distance from a topic, approaching it in a disinterested fashion.

Also a "man" thing—physical courage. (I guess, not quite: physical courage "co-constitutes" masculinist glaciology along with nationalism and colonialism.)

There's criticism of a New York Times article that talks about glaciology adventures, which makes a similar point.

At the heart of this chunk is the claim that glaciology excludes women because of a narrative of scientific objectivity and physical adventure. This is a strong claim! It's not enough to say, hey, sure, sounds good. Is it true?