1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice https://t.co/TNE4tuLkqN
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
Same covid-19 mutations are appearing in different places, which may or may not be strange....
41,000 mutations documented in 880 lineages.
Most in spike protein
What explains it?
2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2 https://t.co/B3eR764c1Z
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
1. Reversion of molecularly engineered, partially attenuated, very virulent infectious bursal disease virus during infection of commercial chickenshttps://t.co/wOg1Ekl3Xp
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 24, 2021
2. Reversion to Virulence of Attenuated Canine Distemper Virus In Vivo and In Vitrohttps://t.co/xhjOEYEWTY
3. pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replicationhttps://t.co/jHmujgDVAC
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 24, 2021
4. Genetic suppression in
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 24, 2021
reovirus: Ramig et al. 1977
papovavirus: Shortle et al. 1979
picornavirus: King et al. 1980
vaccinia virus: McFadden et al. 1980
influenza virus: Tolpin et al. 1981
herpesvirus: Hall and Almey 1982
adenovirus: Kruijer et al. 1983https://t.co/4zARJZWBzk
5. reversion to virulence of live attenuated vaccines
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 24, 2021
1. Evolutionary reversion of live viral vaccines: Can genetic engineering subdue it?https://t.co/9lY6ji88Gr
2. Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoVhttps://t.co/ogvKaqiQj8
6. reversion to virulence of live attenuated vaccines
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 24, 2021
3. The double-edged sword: How evolution can make or break a live-attenuated virus vaccinehttps://t.co/jRJNTAR6tn
4. Selection Versus Mutation: Reducing the Risk of Vaccine Reversionhttps://t.co/dkVs3wTkve
7. NSP16 mutant reverts in immune-compromised model
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 24, 2021
and SARS-CoV dNSP16 can revert to virulence
Menachery, Yount & Baric 2018
Combination attenuation offers strategy for live-attenuated coronavirus vaccineshttps://t.co/q2oQQzc1SG pic.twitter.com/RhnBtrGhVW
Was sars-cov-2 or its progenitor adapted to hACE2 during serial passage in human xenograft lung-transplanted mice at WIV?
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 20, 2021
We know that several mink variants and B.1.1.7 are well adapted to murine ACE2.
This may imply reversion of sars-cov-2 to a murine adapted progenitor.
Just to annoy people
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
Virology: the problem with \u2018leaky\u2019 vaccines
Fresh evidence supports the theory that some vaccines lead to the evolution of more virulent viral strainshttps://t.co/ttyM9J2idI
B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.https://t.co/9Z4oJmkcKj pic.twitter.com/1Q65DpHboK
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
Mice!
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
A mink-associated variant carrying \u0394(69-70)-Y453F-F486L-N501T-M1229I mutations was also able to utilize mouse Ace2. In addition, all variants carrying an N501Y mutation, a shared feature of UK, South Africa, & Brazil VOC strains, efficiently use mouse Ace2 orthologs.
Topolino!
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
"Moreover, the K417N-E484K-N501Y mutations found in the South Africa variant 501Y.V2 even enable the virus to utilize rat Ace2 more efficiently than using human ACE2. These data suggest that rats and mice may (have) be(en) able to harbor and spread these variants"? pic.twitter.com/kC3dVwmTyg
Above taken from:
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
Circulating SARS-CoV-2 variants B.1.1.7, 501Y.V2, and P.1 have gained ability to utilize rat and mouse Ace2 and altered in vitro sensitivity to neutralizing antibodies and ACE2-Ighttps://t.co/j9qEcUz4ea
Well worth a read! pic.twitter.com/w6VLjhpjf4
even the mink variants were mouse ACE2 adapted, what a surprise...now, who would have expected that? pic.twitter.com/AVPwXeJ1tT
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
More from Billy Bostickson 🏴👁&👁 🆓
1. Omicron Thread - A Compilation of Opinions
"finally, the time has slip and slid its slimy course through to us - and we're the vicious bastards of the new generation. we do not relent, and we should not be held to account for our ancestral faults"
https://t.co/mhJO6yOQRE
2. The Letter Chosen by the WHO
"It's amazing that the Xi variant seems to have somehow managed to evade detection..."
via @readomain
Why 'Omicron', Not 'Nu' or 'Xi'?
WHO Says Two Letters in Greek Alphabet Jumped to 'Avoid Stigma'
https://t.co/xnGR9XK2tF
3. The Omicron variant has been found in nearly every province of South Africa, as well as Botswana, Belgium, Israel, UK and Hong Kong.
This month, Israel held an exercise, The “Omega Exercise”, meant to prepare for a hypothetical, new COVID-19
4. Omicron Infographic
(appeared in Germany and Italy now)
https://t.co/oNFYBH1F1o
5. Overview of Omicron (B.1.1.529) from @nicd_sa
https://t.co/HN9csJqK0z
"finally, the time has slip and slid its slimy course through to us - and we're the vicious bastards of the new generation. we do not relent, and we should not be held to account for our ancestral faults"
https://t.co/mhJO6yOQRE
Here is how B.1.1.529 (#Omicron #B11529) compares to Alpha, Beta, Gamma, Delta variants.
— nference (@_nference) November 27, 2021
Omicron has highest novel Spike mutations including striking cluster on the "crown" suggesting significant selection pressure & antigenic distinction from prior strains
(Credits: nference) pic.twitter.com/4oZQbjhbG8
2. The Letter Chosen by the WHO
"It's amazing that the Xi variant seems to have somehow managed to evade detection..."
via @readomain
Why 'Omicron', Not 'Nu' or 'Xi'?
WHO Says Two Letters in Greek Alphabet Jumped to 'Avoid Stigma'
https://t.co/xnGR9XK2tF
3. The Omicron variant has been found in nearly every province of South Africa, as well as Botswana, Belgium, Israel, UK and Hong Kong.
This month, Israel held an exercise, The “Omega Exercise”, meant to prepare for a hypothetical, new COVID-19
4. Omicron Infographic
(appeared in Germany and Italy now)
https://t.co/oNFYBH1F1o
5. Overview of Omicron (B.1.1.529) from @nicd_sa
https://t.co/HN9csJqK0z
Prof @Tuliodna is giving an insightful overview of the #NewVariant #B11529 pic.twitter.com/VnFBrj2pOT
— NICD (@nicd_sa) November 25, 2021
Tip from the Monkey
Pangolins, September 2019 and PLA are the key to this mystery
Stay Tuned!
1. Yang
2. A jacobin capuchin dangling a flagellin pangolin on a javelin while playing a mandolin and strangling a mannequin on a paladin's palanquin, said Saladin
More to come tomorrow!
3. Yigang Tong
https://t.co/CYtqYorhzH
Archived: https://t.co/ncz5ruwE2W
4. YT Interview
Some bats & pangolins carry viruses related with SARS-CoV-2, found in SE Asia and in Yunnan, & the pangolins carrying SARS-CoV-2 related viruses were smuggled from SE Asia, so there is a possibility that SARS-CoV-2 were coming from
Pangolins, September 2019 and PLA are the key to this mystery
Stay Tuned!
1. Yang
Meet Yang Ruifu, CCP's biological weapons expert https://t.co/JjB9TLEO95 via @Gnews202064
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) October 11, 2020
Interesting expose of China's top bioweapons expert who oversaw fake pangolin research
Paper 1: https://t.co/TrXESKLYmJ
Paper 2:https://t.co/9LSJTNCn3l
Pangolinhttps://t.co/2FUAzWyOcv pic.twitter.com/I2QMXgnkBJ
2. A jacobin capuchin dangling a flagellin pangolin on a javelin while playing a mandolin and strangling a mannequin on a paladin's palanquin, said Saladin
More to come tomorrow!
3. Yigang Tong
https://t.co/CYtqYorhzH
Archived: https://t.co/ncz5ruwE2W
4. YT Interview
Some bats & pangolins carry viruses related with SARS-CoV-2, found in SE Asia and in Yunnan, & the pangolins carrying SARS-CoV-2 related viruses were smuggled from SE Asia, so there is a possibility that SARS-CoV-2 were coming from
@snip96581187 @Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen Clearly, because as I have been saying for 8 months now, DTRA and DARPA have been using Ecohealth and UC Davis to collect novel pathogens for gain of function work back in the USA. I have documented this in many threads which I will post here just to annoy everyone.
@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
28. Before moving on to DARPA, let's look at DTRA:
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) July 31, 2020
A must read!
It is astonishing the number of pies they had their dirty little fingers poking into:
Note John Epstein and Kevin Olival from EcoHealth Alliance are key figures in DTRA:https://t.co/O4QwVWrm7m pic.twitter.com/cnNGZ7AApj
@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
24. DTRA Network for Collection of Viruses
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 9, 2021
7. DTRA - Metabiota - One Health - Ecohealth
Bat Research Networks and Viral Surveillance: Gaps and Opportunities in Western Asia pic.twitter.com/SOqSSXF3pa
@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
That is the key question
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 5, 2021
1. DARPA/DTRA use NGOs like Ecohealth or Metabiota to collect new pathogens
2. They are sent to US labs (Mailman, Rocky Mountain, Atlanta CDC, UNC, USAMRIID) for GOF work by Lipkin, Nichols, Rasmussen, Baric, Dension, Munster, etchttps://t.co/wqhHK7uZO6
@Daoyu15 @lab_leak @walkaboutrick @ydeigin @Ayjchan @franciscodeasis @TheSeeker268 @angie_rasmussen
1. I wonder why Dr. Angela Rasmussen is so so upset & full of almost palpable venom about a Hypothesis and a "What if" question by @nicholsonbaker8 in the @NYMag https://t.co/a6lxtJLpKR
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 5, 2021
Did I hear someone say "DARPA"?
Did I hear someone say "DTRA"?https://t.co/i27mpxJDw2 pic.twitter.com/x4X3QPnTMS
Digital Operations Group (DOG) 77th Brigade
A pathetic digestive biscuit munching bunch of British Berks from civvy street whose badge dishonours the Chindits.
Sleazy Media Manipulators who usually fail to deliver "influencing activity & products" to counter narratives of others
“If everybody is thinking alike then somebody isn’t thinking”
Just about sums up their Covid-19 "narrative"
“Behavioural change is our USP [unique selling point]”
They fail every time, doubt they could even sell their asses to soldiers at Denison Barracks
More on this pathetic bunch of Trolls scrounging a living from honest taxpayers' money to sell offal scraped off the Butcher's
Why are these little British trolls all over Twitter lately?
The have been ordered to counter "Covid- 19 Myths"
One of these is Myth No.3 (see image)
2004-Factsheet-Russia-Myths-COVID-19_en.pdf
https://t.co/PxjOPJjWH0
🐇🕳️💩
https://t.co/r6n1t1wYvG
https://t.co/aLuzKktcZv
https://t.co/zFmaD9yadQ
https://t.co/UkSdag9U5H
https://t.co/3N3XwF9Drj
https://t.co/ZyKXL2uLzB
https://t.co/OIlpoMVMcA
https://t.co/e0W3qWkwvL
https://t.co/NMdiTqtU4u
https://t.co/gzYiVWeTJf
A pathetic digestive biscuit munching bunch of British Berks from civvy street whose badge dishonours the Chindits.
Sleazy Media Manipulators who usually fail to deliver "influencing activity & products" to counter narratives of others
“If everybody is thinking alike then somebody isn’t thinking”
Just about sums up their Covid-19 "narrative"
“Behavioural change is our USP [unique selling point]”
They fail every time, doubt they could even sell their asses to soldiers at Denison Barracks
More on this pathetic bunch of Trolls scrounging a living from honest taxpayers' money to sell offal scraped off the Butcher's
Why are these little British trolls all over Twitter lately?
The have been ordered to counter "Covid- 19 Myths"
One of these is Myth No.3 (see image)
2004-Factsheet-Russia-Myths-COVID-19_en.pdf
https://t.co/PxjOPJjWH0
🐇🕳️💩
https://t.co/r6n1t1wYvG
https://t.co/aLuzKktcZv
https://t.co/zFmaD9yadQ
https://t.co/UkSdag9U5H
https://t.co/3N3XwF9Drj
https://t.co/ZyKXL2uLzB
https://t.co/OIlpoMVMcA
https://t.co/e0W3qWkwvL
https://t.co/NMdiTqtU4u
https://t.co/gzYiVWeTJf
More from All
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My top 10 tweets of the year
A thread 👇
https://t.co/xj4js6shhy
https://t.co/b81zoW6u1d
https://t.co/1147it02zs
https://t.co/A7XCU5fC2m
A thread 👇
https://t.co/xj4js6shhy
Entrepreneur\u2019s mind.
— James Clear (@JamesClear) August 22, 2020
Athlete\u2019s body.
Artist\u2019s soul.
https://t.co/b81zoW6u1d
When you choose who to follow on Twitter, you are choosing your future thoughts.
— James Clear (@JamesClear) October 3, 2020
https://t.co/1147it02zs
Working on a problem reduces the fear of it.
— James Clear (@JamesClear) August 30, 2020
It\u2019s hard to fear a problem when you are making progress on it\u2014even if progress is imperfect and slow.
Action relieves anxiety.
https://t.co/A7XCU5fC2m
We often avoid taking action because we think "I need to learn more," but the best way to learn is often by taking action.
— James Clear (@JamesClear) September 23, 2020
TradingView isn't just charts
It's much more powerful than you think
9 things TradingView can do, you'll wish you knew yesterday: 🧵
Collaborated with @niki_poojary
1/ Free Multi Timeframe Analysis
Step 1. Download Vivaldi Browser
Step 2. Login to trading view
Step 3. Open bank nifty chart in 4 separate windows
Step 4. Click on the first tab and shift + click by mouse on the last tab.
Step 5. Select "Tile all 4 tabs"
What happens is you get 4 charts joint on one screen.
Refer to the attached picture.
The best part about this is this is absolutely free to do.
Also, do note:
I do not have the paid version of trading view.
2/ Free Multiple Watchlists
Go through this informative thread where @sarosijghosh teaches you how to create multiple free watchlists in the free
3/ Free Segregation into different headers/sectors
You can create multiple sections sector-wise for free.
1. Long tap on any index/stock and click on "Add section above."
2. Secgregate the stocks/indices based on where they belong.
Kinda like how I did in the picture below.
It's much more powerful than you think
9 things TradingView can do, you'll wish you knew yesterday: 🧵
Collaborated with @niki_poojary
1/ Free Multi Timeframe Analysis
Step 1. Download Vivaldi Browser
Step 2. Login to trading view
Step 3. Open bank nifty chart in 4 separate windows
Step 4. Click on the first tab and shift + click by mouse on the last tab.
Step 5. Select "Tile all 4 tabs"
What happens is you get 4 charts joint on one screen.
Refer to the attached picture.
The best part about this is this is absolutely free to do.
Also, do note:
I do not have the paid version of trading view.
2/ Free Multiple Watchlists
Go through this informative thread where @sarosijghosh teaches you how to create multiple free watchlists in the free
\U0001d5e0\U0001d602\U0001d5f9\U0001d601\U0001d5f6\U0001d5fd\U0001d5f9\U0001d5f2 \U0001d600\U0001d5f2\U0001d5f0\U0001d601\U0001d5fc\U0001d5ff \U0001d604\U0001d5ee\U0001d601\U0001d5f0\U0001d5f5\U0001d5f9\U0001d5f6\U0001d600\U0001d601 \U0001d5fc\U0001d5fb \U0001d5e7\U0001d5ff\U0001d5ee\U0001d5f1\U0001d5f6\U0001d5fb\U0001d5f4\U0001d603\U0001d5f6\U0001d5f2\U0001d604 \U0001d602\U0001d600\U0001d5f6\U0001d5fb\U0001d5f4 \U0001d601\U0001d5f5\U0001d5f2 \U0001d5d9\U0001d5e5\U0001d5d8\U0001d5d8 \U0001d603\U0001d5f2\U0001d5ff\U0001d600\U0001d5f6\U0001d5fc\U0001d5fb!
— Sarosij Ghosh (@sarosijghosh) September 18, 2021
A THREAD \U0001f9f5
Please Like and Re-Tweet. It took a lot of effort to put this together. #StockMarket #TradingView #trading #watchlist #Nifty500 #stockstowatch
3/ Free Segregation into different headers/sectors
You can create multiple sections sector-wise for free.
1. Long tap on any index/stock and click on "Add section above."
2. Secgregate the stocks/indices based on where they belong.
Kinda like how I did in the picture below.
This is NONSENSE. The people who take photos with their books on instagram are known to be voracious readers who graciously take time to review books and recommend them to their followers. Part of their medium is to take elaborate, beautiful photos of books. Die mad, Guardian.
THEY DO READ THEM, YOU JUDGY, RACOON-PICKED TRASH BIN
If you come for Bookstagram, i will fight you.
In appreciation, here are some of my favourite bookstagrams of my books: (photos by lit_nerd37, mybookacademy, bookswrotemystory, and scorpio_books)
Beautifully read: why bookselfies are all over Instagram https://t.co/pBQA3JY0xm
— Guardian Books (@GuardianBooks) October 30, 2018
THEY DO READ THEM, YOU JUDGY, RACOON-PICKED TRASH BIN
If you come for Bookstagram, i will fight you.
In appreciation, here are some of my favourite bookstagrams of my books: (photos by lit_nerd37, mybookacademy, bookswrotemystory, and scorpio_books)