BC VLP

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rubic3n
@rubic3n 3 years, 4 months ago 706 views

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Virus-Like Particles: Revolutionary Platforms for Developing Vaccines Against Emerging Infectious Diseases
https://t.co/gm76Pzw0KT

In memoriam Nicola Bidoli

VLP applications characteristics challenges

VLP Induction of innate and adaptive immunological responses (A) humoral immunity; (B) cell-mediated immunity) by VLPs

VLPs Advantages and limitations of different expression systems for the development of virus-like particles.

VLP vaccines against different viruses and parasites.

VLP - how to produce them
Proposed production system and mechanism of action of SARS-CoV2 virus-like particle vaccine. Plasmids encoding the structural proteins (S, N, M, and E) of the SARS-CoV2 can be transfected into an appropriate mammalian cell line.

More from rubic3n

rubic3n
@rubic3n

@PParzival Es gabe eine parallele Entwicklung mit der Entwicklung der mRNA. Im Packet mit LNP (Lipid Nano Partikeln, den Vehikeln), und Graphene (zur Trennung im Herstellungsprozess, aber auch mögliche andere Effekte wie Tight Junction Öffnung) und der breiten Produktpalette der Hydrogels.

Mit einer nie da gewesenen Hoffnung auf:
- neue industrielle Revolution (meist Graphene basiert, durchsichtig, stretchy, SPIN tech fähig, mit regelbarer Ladung, Magnetizität in ALLEN Lebensbereichen) -damit MEHR PROFIT für die Computerindustrie mit geringeren Entwicklungssprüngen

2011 Ein bedeutendes Jahr mit großem finanziellen Commitment der großen
2012 George Church Emergency Summit on rogue self-replicating Nano Bots (da noch nicht eingetreten, aber den Giftkochern schon bewußt)
2015 Buy-in in alle großen mRNA Impfstoff Platformen.

Auch 2015, PR roll-out Gates Concept Designerin Health (Impfstoffe und Weltkörperkontroll Organisation (natürlich nennen sie es anders, übrigens nicht WHO) Sue Desmond-Hellmann
2016 großer Moderna Niederschlag mit tödlichen Vehikel
Gleichzeitig Push neue LNP Entwicklung

2018 Baric plug in your spike Lego Technik einsatzbereit. Gates Munich Security Conference 'Es wird einen Terroristischen Virenanschlag geben'; Fauci 'There is going to be a surprise outbreak'
2018 Enigma Lieferung nach Wuhan, damit zweite 'No see um' DNA RNA Technologie für Lego

rubic3n
@rubic3n

@Keane1975 Die Forschung mit Virenmanipulation und mRNA Impfstoffen geht dem schon seitlich weit voraus.
Nachfolgend
- zum Bau des Labors in Wuhan durch BioMerieux -> Bancel jetzt Moderna
- Werbebroschüre BioMerieux (CEPI GAVI Einbindung)
- Moderna ominöser geheimer weiterer Impfstoff
1

Bau des Labors in Wuhan BioMerieux Beteiligung
2004

CCP
US
France
all in.
Gates Biontech, Biomerieux Moderna, Gilead Trump
All in.
Who is more?@franciscodeasis https://t.co/ADowRaYHsL
— rubic3n (@rubic3n) February 19, 2021

Bancel BioMerieux

However, through the Bancel (WEF), James Le Duc, Biomerieux gateway France still stayed pretty well in the game - however, sophisticatedly covered. Quite a camouflage masterpiece.

This is where 100Mio EU funding went?https://t.co/hFvdBS62rY https://t.co/jkJgyBdiYk pic.twitter.com/rulfKhKIWw
— rubic3n (@rubic3n) August 29, 2021

Mehr zum Bau des Labors durch BioMerieus in Wuhan (Stephane Bancel ex BioMerieux jetzt

biomerieux has the lab in lyon and they also made the lab in wuhan. https://t.co/dmgTLZ1kEK
— Bianca, fight the abolition of human rights (@Bianca50406170) November 16, 2021

Bancel BioMerieux Wuhan

I\u2019m wondering if/when this will catch on... https://t.co/PoBxz4JyiW pic.twitter.com/1rZFot4uxr
— Jesse \u201cEpstein+WEF+\U0001f1fa\U0001f1f3=Malthusianism\U0001f489\u201d Matchey (@JesseMatchey) January 9, 2022

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rubic3n
@rubic3n

Novavax
Matrix M coating for cancer therapeutics

Following in the orchestrated wave if 'Emerging infectious diseases'.
A good cloak to hide a nasty machinery beneath.

2022
https://t.co/gm76Pzw0KT
further articles in following tweet

2017 Biomerieux
https://t.co/hrCU2xVi3U
2016
https://t.co/ZpyQ4WeUWZ
2016
https://t.co/ua10Y0fu0Z
2015 mice

rubic3n
@rubic3n

Fondation Merieux
2017
Pushing the
CEPI Dialogue

Excellent presentation to see, how they, including Bancel, had layed out the narrative.
Quess, what they had specifically included in their list of targeted viruses?

https://t.co/J5FDe6W986

Fondation Merieux 2017
CEPI
Almost basking about their list being more inclusive, more emergent viruses based.
https://t.co/J5FDe6W986

Fondation Merieux 2017
Narrative: "Look, what ZIKA has done to your populace. Nasty ZIKA."

How much of that ZIKA damage was actually related to a virus? Was there a computer guy, who had invested in mosquitos as a vector?

https://t.co/J5FDe6W986

Fondation Merieux 2017
What is the advanges of a programme like CEPI.

And for who?

Let me translate: They want a coordinated vaccine production, with only one strong production pipeline, and solidly regulated pathsways.
Provide the incentives for big pharma.

They've made it.

Vision - look at nasty ZIKA, you surely do not want that
Mission - get the pipeline going of (only) the big ones
Scope - the anti-cancer platforms with their DNA, mRNA basis fit perfectly. They so far do not sell very well, but they could be recycled.

Correct me, if I am wrong.

rubic3n
@rubic3n

80% of diseases not treatable with 'conventional medicine'. Protein treatment as an alternative with drawbacks.
An 80% market for mRNA. Yet, the vector is the bottleneck causing the limitation.
Viral V is almost a 'use once only' bcs of antibody formation.
LNP sole way to push.

READ THE INTRODUCTION... https://t.co/1k4qZeutit
— Not Your Mom (@Notyour28981739) December 24, 2021

mRNA Therapy - with a gargantuan market - in dire need for a vector.
Viral vectors as a dead ally until 2015.
mRNA Therapy meets enormous resentments.

Luckily, billions of people have now got first hand experience. Obviously, AZ was not that useful in the general drift.

LNP instead of a vector
PFIZER BioNtech

ALC-0315
ALC-0159, DSPC
"This product is for research use only and not for human use."
https://t.co/tNsG5wxVCT

'EMA Zulassung ohne

https://t.co/rSOxRFTZwH https://t.co/gi40e7mUqI https://t.co/3yAElKnXgs https://t.co/QXYZbFxHRq https://t.co/Nb0q026Zvj
— Lexa W. \U0001f1e9\U0001f1ea (@rebew_lexa) December 22, 2021

Official statement by Echelon
Paraphrased - "we do produce it, but only for use in labs.
Pfizer get theirs from other companies. With them it is safe in humans."

No study data presented
A reference to GMP as 'safe in humans'

ALC-0315
ALC-0159, DSPC

PFIZER LNP

This paper claims "It is just like another fatty compound. You eat salad oil and chips as well"

https://t.co/uncdUpkFnI

No, it is not.

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Nicolas
@necolas

A brief analysis and comparison of the CSS for Twitter's PWA vs Twitter's legacy desktop website. The difference is dramatic and I'll touch on some reasons why.

Legacy site *downloads* ~630 KB CSS per theme and writing direction.

6,769 rules
9,252 selectors
16.7k declarations
3,370 unique declarations
44 media queries
36 unique colors
50 unique background colors
46 unique font sizes
39 unique z-indices

https://t.co/qyl4Bt1i5x

PWA *incrementally generates* ~30 KB CSS that handles all themes and writing directions.

735 rules
740 selectors
757 declarations
730 unique declarations
0 media queries
11 unique colors
32 unique background colors
15 unique font sizes
7 unique z-indices

https://t.co/w7oNG5KUkJ

The legacy site's CSS is what happens when hundreds of people directly write CSS over many years. Specificity wars, redundancy, a house of cards that can't be fixed. The result is extremely inefficient and error-prone styling that punishes users and developers.

The PWA's CSS is generated on-demand by a JS framework that manages styles and outputs "atomic CSS". The framework can enforce strict constraints and perform optimisations, which is why the CSS is so much smaller and safer. Style conflicts and unbounded CSS growth are avoided.

Richard James
@RJSHutton

I think a plausible explanation is that whatever Corbyn says or does, his critics will denounce - no matter how much hypocrisy it necessitates.

One of the oddest features of the Labour tax row is how raising allowances, which the media allowed the LDs to describe as progressive (in spite of evidence to contrary) through the coalition years, is now seen by everyone as very right wing
— Tom Clark (@prospect_clark) November 2, 2018

Corbyn opposes the exploitation of foreign sweatshop-workers - Labour MPs complain he's like Nigel

He speaks up in defence of migrants - Labour MPs whinge that he's not listening to the public's very real concerns about immigration:

He's wrong to prioritise Labour Party members over the public:

He's wrong to prioritise the public over Labour Party

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Kanekoa
@KanekoaTheGreat

*The Evidence Collection*

There is overwhelming evidence of election fraud. Therefore it is the duty of the Executive, Legislative, & Judicial branches to throw out the fraudulent votes & to honor their oath to protect & defend the Constitution of the USA.🇺🇸🦅

A list below.🔻

1/ Navarro Report: The Immaculate Deception - Six Key Dimensions of Election Irregularities -

2/ Analysis of 3,000 U.S. counties shows Joe Biden received 5.6 % more votes in counties using Dominion Voting Systems (Video) -

3/ Antrim Michigan Dominion Voting Systems Forensics Report -

4/ Evidence Grows: ’20 Election Was Rigged -

$\uc2e0\ub150\uc758\uc0ac\ub098\uc774$

신념의사나이...
@Belposto_korea

What does Gold- Backed mean?
The Chinese Elders have been accumulating gold for hundreds of years. They are gold-rich. Some of their gold was loaned to the Central Banking System so that it could fund the rebuilding of Europe after the many war-torn years from World Wars I and II

BTW they never returned it but used it to start their financial empire to enslave humanity. This is the Central Bank Banking System./2

Maybe this is why one of the conditions to use their gold for the QFS is the demise and full disclosure of the Central Bank banking system before the RV can take place./3

The Elders have caves of hidden gold and are now using it to gold-back the currencies in the QFS for every country in the world. It is important to understand that the QFS and the money it is about to release is all brand-new currency./4

It was designed by the Alliance to fund the new financial system that will reset all Currencies of the world to Gold-Backed currency./5

$Ranvijay Singh\U0001f1ee\U0001f1f3$

Ranvijay Singh🇮🇳...
@ranvijayT90

#Thread Two divine forms of Khatu Shyam ji...

On the day of Amavasya, devotees get the darshan of Shyam Baba in Shyam varan (black color). In ordinary days, the form of Baba is saffron. The reason for this is a custom. The real head of Shyam Baba which had appeared from Shyam Kund is of Shyam varan.

Every day Shyam Baba's grand Shringar is done by Pujaris. The main part of Shyam Baba's shringar is Tilak. This Shringar is done by the members of Nij Mandir sevaks. The sevaks of the Nij Mandir do sandalwood tilak to Baba everyday in the auspicious time.

This Divine Tilak is applied from the forehead to the nose. When Baba is given a bath by sevaks, this tilak comes off. Then in the auspicious time, the sevaks again apply tilak to Baba.

There is no auspicious time on the Amavasya. Because of this, tilak is not done on that day. That's why devotees have darshan of Shyam Baba on the Amavasya only in the actual real form (Shyam Swaroop). Baba's tilak is done on Amavasya only on the day of Deepawali.