It makes for a brilliant narrative. It melts your hearts. And you get to play saviour of the oppressed by outraging. /1
https://t.co/odzm9VTdwZ
Thread for today. /0
It makes for a brilliant narrative. It melts your hearts. And you get to play saviour of the oppressed by outraging. /1
Amazon are the lungs of the world. Never mind that most of the world's oxygen production happens in open oceans. But these are harmless ones. Of course, we all love to maintain forests.
For instance - take this: coral reefs will be permanently gone if mean / median temperatures raise by 1°C ..
But, really - how? Then you get a lecture on how CO2 will affect calcification.
Dig a bit deeper from another angle+
And the ocean temps were quite high too.
Here is the catch - Corals have been in existence for the last one billion years (or more).
Second one are news like the one quoted above. (Shark eggs are unviable **due to global warming**).
This is a false flag. Is there a correlation between these two? Maybe.
Intriguing and relevant are lessons from the fruit fly!
https://t.co/8Q9ARW5iV5
Some background: information in DNA is controlled by short segments of DNA called enhancers. In 2010, Frankel et al found a particular enhancer that seemed redundant.
They deleted this "redundant" copy of the enhancer, and saw that it had zero impact on development. But then - when they deleted it and ++
That is, this seemingly redundant enhancer was a contingency plan put in place by nature to deal with unforeseen events.
It is entirely coincidental that the best example to ++
Now we can at least use these lessons to ask questions about Sharks and corals!
If Drosophila, a relatively recent organism, can have contingency plans - won't the sharks have it?
Remember - the entire argument isn't about whether or not warming occurs .. but it is about whether the scaremongering holds water.
If we have understood something about life, it is that it survives.
No. That is not the message. It is that the lower an organism is on the evolutionary scale, the lesser it will be hit.
Someone mentioned polar Bears. They will be hit. They are complex organisms with specific habitat reqs.
Guess the most fastidious numerous animal? Humans.
Climate change - irrespective of the cause, is seen to affect glaciers. No amount of wishing away changes it.
The complex web of life means that the over exploitation is the problem. So what is the way ahead?
All the measures (green tech) is just band aid on a open surgical wound. You can assuage your heart .. but it won't stop.
Take the example of China. ~1.25B people.
What does it mean to be a first world country? Typically two things: food + water surplus, energy surplus.
What did China do to address these problems?
https://t.co/2MkOv6O6CG
And they have been doing it for almost two decades now.
What the white man did to American Bison, Chinese are doing to the oceans. In a far larger scale.
Last is Energy: China gets as much as 60% of its total energy from burning coal.
Energy is the currency of civilization.
Everyone wants AC to protect them from the summer. Everyone wants a car. Everyone wants fresh water and food.
Nope. Global warming isn't going anywhere.
Politically incorrect.
For now, understand that anyone promising to do this within the next 30yrs is bullshitting.
Why? After India, it will be the turn of entire African continent to become energy and food surplus.
Like all things humans - civilizational values are key in resolving this issue.
Pick your value systems carefully.
More from Science
@mugecevik is an excellent scientist and a responsible professional. She likely read the paper more carefully than most. She grasped some of its strengths and weaknesses that are not apparent from a cursory glance. Below, I will mention a few points some may have missed.
1/
The paper does NOT evaluate the effect of school closures. Instead it conflates all ‘educational settings' into a single category, which includes universities.
2/
The paper primarily evaluates data from March and April 2020. The article is not particularly clear about this limitation, but the information can be found in the hefty supplementary material.
3/
The authors applied four different regression methods (some fancier than others) to the same data. The outcomes of the different regression models are correlated (enough to reach statistical significance), but they vary a lot. (heat map on the right below).
4/
The effect of individual interventions is extremely difficult to disentangle as the authors stress themselves. There is a very large number of interventions considered and the model was run on 49 countries and 26 US States (and not >200 countries).
5/
1/
I've recently come across a disinformation around evidence relating to school closures and community transmission that's been platformed prominently. This arises from flawed understanding of the data that underlies this evidence, and the methodologies used in these studies. pic.twitter.com/VM7cVKghgj
— Deepti Gurdasani (@dgurdasani1) February 1, 2021
The paper does NOT evaluate the effect of school closures. Instead it conflates all ‘educational settings' into a single category, which includes universities.
2/
The paper primarily evaluates data from March and April 2020. The article is not particularly clear about this limitation, but the information can be found in the hefty supplementary material.
3/

The authors applied four different regression methods (some fancier than others) to the same data. The outcomes of the different regression models are correlated (enough to reach statistical significance), but they vary a lot. (heat map on the right below).
4/

The effect of individual interventions is extremely difficult to disentangle as the authors stress themselves. There is a very large number of interventions considered and the model was run on 49 countries and 26 US States (and not >200 countries).
5/

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Keep dwelling on this:
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK

In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa

Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs

Stan Lee’s fictional superheroes lived in the real New York. Here’s where they lived, and why. https://t.co/oV1IGGN8R6
Stan Lee, who died Monday at 95, was born in Manhattan and graduated from DeWitt Clinton High School in the Bronx. His pulp-fiction heroes have come to define much of popular culture in the early 21st century.
Tying Marvel’s stable of pulp-fiction heroes to a real place — New York — served a counterbalance to the sometimes gravity-challenged action and the improbability of the stories. That was just what Stan Lee wanted. https://t.co/rDosqzpP8i
The New York universe hooked readers. And the artists drew what they were familiar with, which made the Marvel universe authentic-looking, down to the water towers atop many of the buildings. https://t.co/rDosqzpP8i
The Avengers Mansion was a Beaux-Arts palace. Fans know it as 890 Fifth Avenue. The Frick Collection, which now occupies the place, uses the address of the front door: 1 East 70th Street.

Stan Lee, who died Monday at 95, was born in Manhattan and graduated from DeWitt Clinton High School in the Bronx. His pulp-fiction heroes have come to define much of popular culture in the early 21st century.
Tying Marvel’s stable of pulp-fiction heroes to a real place — New York — served a counterbalance to the sometimes gravity-challenged action and the improbability of the stories. That was just what Stan Lee wanted. https://t.co/rDosqzpP8i

The New York universe hooked readers. And the artists drew what they were familiar with, which made the Marvel universe authentic-looking, down to the water towers atop many of the buildings. https://t.co/rDosqzpP8i

The Avengers Mansion was a Beaux-Arts palace. Fans know it as 890 Fifth Avenue. The Frick Collection, which now occupies the place, uses the address of the front door: 1 East 70th Street.