Here is another very enjoyable conversation, with @Pandata19’s scientific advisory board member, Dr Jay Bhattacharya. Key ideas in this thread.

We are making world-changing decisions on the basis of evidence that is not very good. Vast scientific evidence tells us that infection fatality rates are much lower than originally expected. A small fraction of people get severe illness. 2/10
The scientific community has been resistant to evidence not supporting the majoritarian view, preferring instead to gin up panic, focusing on the worst case for everything the virus does & the best case for everything lockdowns do, and ignoring the range of uncertainty. 3/10
Academe is a strange place now, with debate stifled. But there's a sense some are opening up to considering opposing views. This is key, since suppression of views stops knowledge from progressing—the end of science. Public health norms of unified messaging complicate this. 4/10
Why did we, from the start, assume we knew nothing about this virus, instead of assuming a reasonable prior? Low susceptibility was evident early on. Assuming any virus is new is hard to square with our deep-time co-evolution with viruses, & their slow evolution. 5/10
A lot of smart people changed their minds about what to do in March, and need to change them back. Our hope has to be that people will lose respect for scientific institutions, and not for science itself. 6/10
From the first day Jay heard about lockdowns, they felt like a violation of everything he knew about public health. Shutting down of schools has been their most shocking manifestation. 7/10
Asymptomatic people and children are at least much less efficient at transmitting. B- and T-cell responses persist after antibody levels have waned, so it is unlikely that people who are reinfected will get severely sick. 8/10
The issue of Long Covid is overstated by the media. Similar to the flu, there are occasional extra-respiratory manifestations, but they appear to be relatively uncommon and seldom serious. 9/10
Fear of the disease prevents young, healthy people from doing the usual thing & shouldering the burden of infection, so the elderly are spared ending up in the exposed group. Then there is an interesting discussion about vaccinations, including who should seek them. Enjoy! 10/10

More from Science

@mugecevik is an excellent scientist and a responsible professional. She likely read the paper more carefully than most. She grasped some of its strengths and weaknesses that are not apparent from a cursory glance. Below, I will mention a few points some may have missed.
1/


The paper does NOT evaluate the effect of school closures. Instead it conflates all ‘educational settings' into a single category, which includes universities.
2/

The paper primarily evaluates data from March and April 2020. The article is not particularly clear about this limitation, but the information can be found in the hefty supplementary material.
3/


The authors applied four different regression methods (some fancier than others) to the same data. The outcomes of the different regression models are correlated (enough to reach statistical significance), but they vary a lot. (heat map on the right below).
4/


The effect of individual interventions is extremely difficult to disentangle as the authors stress themselves. There is a very large number of interventions considered and the model was run on 49 countries and 26 US States (and not >200 countries).
5/

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Oh my Goodness!!!

I might have a panic attack due to excitement!!

Read this thread to the end...I just had an epiphany and my mind is blown. Actually, more than blown. More like OBLITERATED! This is the thing! This is the thing that will blow the entire thing out of the water!


Has this man been concealing his true identity?

Is this man a supposed 'dead' Seal Team Six soldier?

Witness protection to be kept safe until the right moment when all will be revealed?!

Who ELSE is alive that may have faked their death/gone into witness protection?


Were "golden tickets" inside the envelopes??


Are these "golden tickets" going to lead to their ultimate undoing?

Review crumbs on the board re: 'gold'.


#SEALTeam6 Trump re-tweeted this.
The first ever world map was sketched thousands of years ago by Indian saint
“Ramanujacharya” who simply translated the following verse from Mahabharat and gave the world its real face

In Mahabharat,it is described how 'Maharishi Ved Vyasa' gave away his divine vision to Sanjay


Dhritarashtra's charioteer so that he could describe him the events of the upcoming war.

But, even before questions of war could begin, Dhritarashtra asked him to describe how the world looks like from space.

This is how he described the face of the world:

सुदर्शनं प्रवक्ष्यामि द्वीपं तु कुरुनन्दन। परिमण्डलो महाराज द्वीपोऽसौ चक्रसंस्थितः॥
यथा हि पुरुषः पश्येदादर्शे मुखमात्मनः। एवं सुदर्शनद्वीपो दृश्यते चन्द्रमण्डले॥ द्विरंशे पिप्पलस्तत्र द्विरंशे च शशो महान्।

—वेद व्यास, भीष्म पर्व, महाभारत


Meaning:-

हे कुरुनन्दन ! सुदर्शन नामक यह द्वीप चक्र की भाँति गोलाकार स्थित है, जैसे पुरुष दर्पण में अपना मुख देखता है, उसी प्रकार यह द्वीप चन्द्रमण्डल में दिखायी देता है। इसके दो अंशो मे पीपल और दो अंशो मे विशाल शश (खरगोश) दिखायी देता है।


Meaning: "Just like a man sees his face in the mirror, so does the Earth appears in the Universe. In the first part you see leaves of the Peepal Tree, and in the next part you see a Rabbit."

Based on this shloka, Saint Ramanujacharya sketched out the map, but the world laughed