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$Jimmy Bernot PhD \U0001f990\U0001fab1\U0001f3f3\ufe0f\u200d\U0001f308$

Jimmy Bernot PhD 🦐🪱🏳️‍🌈
@JimmyBernot 4 years, 4 months ago 1296 views

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Heres the story of how I volunteered to be infected with 50 parasitic worms (hookworm) for a year as part of a research study. Check out this thread & follow me for more #parasite & marine biology content [t]
#ScienceTwitter
imgs: https://t.co/hH5YsfS0ay https://t.co/kVurE6BbTS

1st some background on the parasites I got. Hookworms are blood-feeding nematodes that live in the intestine of mammals including cats, dogs & humans. ~500 million people are infected with hookworm, mostly in tropical and subtropical areas including the southern USA

Infection with many worms (100+) can cause anemia, which is most problematic in kids, pregnant women, and the elderly. This clinical study was launched to try to develop a vaccine against hookworms to prevent infection

People become infected when baby worms living in the soil penetrate their skin. Baby worms hatch from eggs that infected people poop out. Where plumbing is scarce, poor waste disposal is a common source of heavy infections (100s to 1,000s of worms)

I volunteered to be vaccinated with an experimental hookworm vaccine (I was also paid). After vaccination, the vaccine (or placebo idk) was tested by infecting me with 50 hookworms (Necator americanus) that penetrated my skin from a patch of gauze I wore on my wrist for 1 hour

Within minutes I felt a tingling sensation under the patch. The baby worms were penetrating my skin! The worms sense fatty acids in my skin and release proteolytic enzymes to make it easier to slip between my skin cells and into my blood vessels.

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Kevin McKernan
@Kevin_McKernan

When respected Scientists resign over the false narrative... Take notice... and thank them.

Google Translated Letter from

Prof. Dr. Thomas Aigner,
Department of Geosciences,
University of Tuebingen, Sigwartstrasse 10,
D-72076 Tuebingen Germany

Dear colleagues,
It was with the greatest astonishment, deepest concern, and indeed bewilderment, that I took note of the "7th ad hoc statement" from the National Academy of Sciences Leopoldina on December 8th, 2020.
In my opinion, this paper is not worthy of an honest, critical-

weighing science oriented towards the service and well-being of man. I do not have any medical expertise. However, as a scientist committed to nothing but the pure truth, I take the liberty of speaking up. I feel very alarmed by several points:

1. On November 27, 2020, a group of 22 internationally recognized experts presented the following report on the PCR test, the linchpin of the "pandemic", for the Eurosurveillance magazine:

"External peer review of the RTPCR test to detect SARS-CoV-2 reveals 10 major scientific flaws at the molecular and methodological level: consequences for false positive results". Quote: "This highly questions the scientific validity of the test".

Jambavan
@SirJambavan

https://t.co/odzm9VTdwZ

Thread for today. /0

It is fashionable for people to create sympathy to the unseen / unknown organisms. The poor things that can't stand up and fight for their own existence.

It makes for a brilliant narrative. It melts your hearts. And you get to play saviour of the oppressed by outraging. /1

But, for most part, such things are also false.

Amazon are the lungs of the world. Never mind that most of the world's oxygen production happens in open oceans. But these are harmless ones. Of course, we all love to maintain forests.

However, some things are sheer scare mongering.

For instance - take this: coral reefs will be permanently gone if mean / median temperatures raise by 1°C ..

But, really - how? Then you get a lecture on how CO2 will affect calcification.

Dig a bit deeper from another angle+

+ and you find that the earth was much much warmer during the age of Dinosaurs. So much so, that we had cold blooded lizards growing to sizes of buildings. Surely, there must have been tons of CO2 then!

And the ocean temps were quite high too.

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Navin Kabra
@NGKabra

Did you know that all the nuclear bombs we exploded in the '40s-50s-60s have permanently contaminated all the steel the world has produced since then? All steel in the world is divided into two categories: pre-1945 non-contaminated steel, and post-1945 contaminated steel.

How?

Nuclear bombs (including the tests) create a lot of radioisotopes that are not found in nature. For example Cobalt-60 (a radioactive version of Cobalt-59). And since the 1945 Trinity test, these have all dispersed in the atmosphere.

What does this have to do with steel?

The process of manufacturing steel uses atmospheric air (or atmospheric oxygen). Some of the radioisotopes like Cobalt-60 get pulled in too, and as a result, any steel produced after 1945 has embedded in it some of these radioisotopes, sitting there emitting gamma rays.

Why do we care about traces of radioisotopes in steel? When making Geiger counters, or medical devices to check for radioactive contamination, or astronomical instruments, the emissions from the contaminated steel would interfere with the measurements.

So we need pre-1945 steel

Pre-1945 non-contaminated steel is called "low background steel". And when we need it, where do we get it from?

We go, find pre-World-War-II sunken shipwrecks, and then salvage the steel (and lead) from those to build our instruments which need heavy radiation shielding.

Michael Lin, PhD-MD
@michaelzlin

Fellow academics, when are we going to start fixing our urgent structural problems that strain family bonds and present ongoing barriers to diversifying our educational and scientific leadership? You wonder, what the heck is this guy talking about?
1/n

We’re all very familiar what I am talking about, actually: the impossibility for most academics in the life sciences to do their jobs in a reaonable amount of time, due to more and more demands on writing grants, and to a lesser degree, papers.
2/n

As of yesterday I hadn’t intended to write about this subject, but was wondering as I finished a Saturday of straight work, what happened to all my time? Why has WFH not reduced my pile of tasks to do? Instead why is my to-do list growing bigger and bigger?
3/n

I decided to figure out how much time our jobs actually require. I estimated per year (m=month, w=week, d=day, h=hour):
Teaching: 20h/w x 20w = 400h
Meetings of all sorts: 10h/w x 48w= 480h
Replying to email: 2h/d x 365d = 730h
Attending and giving talks: 2h/w x 50w = 100h
4/n

Papers: If each person needs 2 papers during a 5y stint, and you run a 7.5-person lab, then you need 7.5 papers per 2.5y = 3 papers/y. Throw in a review and it’s 4 papers. If you need 15d at 8h/d per paper, that’s 480h writing papers.
5/n

Sloww
@SlowwCo

11 BIG IDEAS OF PHYSICS

via @BlasMoros of @LTCWRK

(Thread 👇)

1. Galilean Relativity

We can never fully grasp, define, or understand a system we are part of.

“Distance provides perspective” and wisdom in life is often about perspective.

2. The Laws of Thermodynamics

The study of the large-scale behavior of systems exchanging work and heat with connected systems or their environment.

- The Transitive Law

- The Law of Conservation

- The “Contrast Advantage” Law

- The “Absolute Zero” Law

3. Newton’s Laws of Motion

Describe how objects in the world move and react to forces.

- The Inertia Law: An object at rest, stays at rest

- Force = Mass * Acceleration (F = ma)

- The Law of Reciprocity: For every action there is an equal and opposite reaction

4. Complexity

A complex system exhibits emergent behavior due to the collective interaction of many individual agents according to simple rules.

Complex systems are sensitive to original conditions, influenced by feedback loops, and buffeted by random outside variables.

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$ArmaniTalks \U0001f399\U0001f525$

ArmaniTalks 🎙🔥...
@ArmaniTalks

Your Most PRECIOUS Currencies:

-Energy

-Time

-Attention

-Trust

-Love

-Loyalty

-Respect

Only give these currencies to high value people. Never spend these currencies on low value shitheads eg: trolls, weasels, snakes, naysayers etc.

'Wait, I thought money was the most important currency?'

Nah.

Once you adopt abundance mentality, you realize their is no shortage of money.

Making the dollars your most important currency will have you leading an empty life.

Time to flip your perspective.

👇

▪Energy

When you strip yourself to the core, you are an emotional creature.

Emotions are your internal worlds energy.

Harnessing that energy is crucial for leveraging yourself to obtain whatever you want.

You have a finite amount everyday, so spend it wisely.

▪Time

A second that is lost will never be returned.

You start valuing the hell out of this currency the more you mature.

As the years start adding up, you realize time is precious.

You must always have a scarcity mindset towards time.

Once you do so, you will not be lazy.

▪Attention

You can be here, but not present.

Attention is completely mental.

Giving someone your attention means you are clearing up mental bandwidth to make room for them.

Only give your attention to people who help you grow.

For the negative ones?

Ignore their existence

$\u0932\u0916\u094b\u092c\u093e \u0932\u094b\u0916\u0902\u0921\u0947$

लखोबा लोखंडे...
@LakhobaLokhande

Secrets of Ganapati (Author - Keshav Sitaram Thackeray)

This article is taken from Keshav Sitaram Thackeray's book 'Dharmachi Devale and Devalcha Dharma'. In it, Bal Thackeray's father is claiming how the Hindu deity of Ganesha is imaginary.
(1/20)

Buddha is Ashtavinayak and "Ganapati Bappa Morya" is "Chandragupta Morya".

In the era of democracy, the head of state is the President. But in ancient India, there was a Gana culture in the monarchy and the head of that Gana was called Ganapati
(2/20)

In ancient India, a prince named Siddharth Gautam was born in royalty. He later became the king of Shakya Gana in this Gana culture. In time, Siddhartha attained enlightenment.

Let us now understand the difference between a real Ganapati and an imaginary Ganapati.
(3/20)

Some clever Brahmin manuvadis made the real Ganapati the imaginary Ganapati.

Buddha was the king of the Shakya Gana, so people called him Ganaraja. He founded Buddhism and became the head of the Shakyas. As the head of Gana, people used to call Buddha as Ganapati.
(4/20)

But the Brahmins Brahmanized Ganapati and created a false Ganapati. When Buddha used to give the message of Dharma to the people, two words would come out of his message. Chitta and Malla.

Chitta is the body.
Malla means waste
(5/20)

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Roger Grosse
@RogerGrosse

Important paper from Google on large batch optimization. They do impressively careful experiments measuring # iterations needed to achieve target validation error at various batch sizes. The main "surprise" is the lack of surprises. [thread]

https://t.co/7QIx5CFdfJ

The paper is a good example of lots of elements of good experimental design. They validate their metric by showing lots of variants give consistent results. They tune hyperparamters separately for each condition, check that optimum isn't at the endpoints, and measure sensitivity.

They have separate experiments where the hold fixed # iterations and # epochs, which (as they explain) measure very different things. They avoid confounds, such as batch norm's artificial dependence between batch size and regularization strength.

When the experiments are done carefully enough, the results are remarkably consistent between different datasets and architectures. Qualitatively, MNIST behaves just like ImageNet.

Importantly, they don't find any evidence for a "sharp/flat optima" effect whereby better optimization leads to worse final results. They have a good discussion of experimental artifacts/confounds in past papers where such effects were reported.

Indian Quant
@indian_quant

Nano Course On Python For Trading
==========================
Module 1

Python makes it very easy to analyze and visualize time series data when you’re a beginner. It's easier when you don't have to install python on your PC (that's why it's a nano course, you'll learn python...

... on the go). You will not be required to install python in your PC but you will be using an amazing python editor, Google Colab Visit https://t.co/EZt0agsdlV

This course is for anyone out there who is confused, frustrated, and just wants this python/finance thing to work!

In Module 1 of this Nano course, we will learn about :

# Using Google Colab
# Importing libraries
# Making a Random Time Series of Black Field Research Stock (fictional)

# Using Google Colab

Intro link is here on YT: https://t.co/MqMSDBaQri

Create a new Notebook at https://t.co/EZt0agsdlV and name it AnythingOfYourChoice.ipynb

You got your notebook ready and now the game is on!
You can add code in these cells and add as many cells as you want

# Importing Libraries

Imports are pretty standard, with a few exceptions.
For the most part, you can import your libraries by running the import.
Type this in the first cell you see. You need not worry about what each of these does, we will understand it later.

katya adler
@BBCkatyaadler

Again, at such a key moment in UK and at such high political levels, evidence of deep misunderstanding of EU: The PM is under pressure in some quarters to delay #Brexit vote to allow her first to “improve” deal in Brussels BUT EU is determined not to budge at this stage

2) All EU leaders watching tomorrow’s vote. Of course they want to avoid a no deal #Brexit BUT they feel the deal - so painfully negotiated between EU and UK - is too fresh to re-open. Clarifications, yes but fundamental renegotiations, no.

3) The EU’s international reputation as a tough deal-maker is at stake here too. If Brussels now suddenly “gives in” to U.K. on EU red lines (eg backstop) then that would weaken the EU’s reputation in future trade negotiations with other non EU countries

4) Also on backstop the EU is unlikely to cave in to favour a relationship with a leaving member state (UK) against the explicit wishes and ignoring the deep concerns of a continuing member: Ireland.

5) Both the EU and the PM signed up to a guarantee to protect the border between Northern Ireland and the Republic of Ireland. If either the U.K. or EU can leave the backstop unilaterally then this clearly is no longer a guarantee.