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A quick thread on the new variant, pulling together information from news sources, twitter, genomic databases, and word from well-placed peers.
The new variant in the UK consists of several mutations in the spike protein, including ΔH69/ΔV70 deletions & other receptor binding domain mutations such as N501Y.
The variant is described here in this pre-print from @GuptaR_lab.
https://t.co/ui2U1r1ANA
The ΔH69/ΔV70 variant continues to increase quite rapidly as a proportion of overall positives (roughly doubling in the last 2 to three days), and is apparently now the dominant strain in test positives in some regions.
Extensive efforts have gone into enhanced surveillance for the ΔH69/ΔV70 deletion with and without RBD mutations, and it is good that we are aware of this.
There is a need for calm and rational thinking, and more evidence is needed.
But the early data is certainly concerning
Cabinet has been summoned for call at lunchtime. Lots of concern about new data on virus in parts of England, feels like fast moving situation. https://t.co/308YsJEVGw
— Nick Eardley (@nickeardleybbc) December 19, 2020
The new variant in the UK consists of several mutations in the spike protein, including ΔH69/ΔV70 deletions & other receptor binding domain mutations such as N501Y.
The variant is described here in this pre-print from @GuptaR_lab.
https://t.co/ui2U1r1ANA
The ΔH69/ΔV70 variant continues to increase quite rapidly as a proportion of overall positives (roughly doubling in the last 2 to three days), and is apparently now the dominant strain in test positives in some regions.
Extensive efforts have gone into enhanced surveillance for the ΔH69/ΔV70 deletion with and without RBD mutations, and it is good that we are aware of this.
There is a need for calm and rational thinking, and more evidence is needed.
But the early data is certainly concerning
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A thread 👇
https://t.co/xj4js6shhy
Entrepreneur\u2019s mind.
— James Clear (@JamesClear) August 22, 2020
Athlete\u2019s body.
Artist\u2019s soul.
https://t.co/b81zoW6u1d
When you choose who to follow on Twitter, you are choosing your future thoughts.
— James Clear (@JamesClear) October 3, 2020
https://t.co/1147it02zs
Working on a problem reduces the fear of it.
— James Clear (@JamesClear) August 30, 2020
It\u2019s hard to fear a problem when you are making progress on it\u2014even if progress is imperfect and slow.
Action relieves anxiety.
https://t.co/A7XCU5fC2m
We often avoid taking action because we think "I need to learn more," but the best way to learn is often by taking action.
— James Clear (@JamesClear) September 23, 2020