Ronald Reagan called Medicare & Medicaid dangerous socialism in 1961... he was a right winger of the Barry Goldwater variety, not the warm and fuzzy presidential muppet he has become in his canonization by the 1980s Alex P. Keatons in the commentariat.
More from History
TIL:
- first Western detective stories translated & published in Japan in *1863*--that's pre-Meiji, even!
- first Chinese-written detective stories featuring Western-style detectives starred women as both detectives and criminals were published in 1907--author Lü Simian (!).
Quote: “This case is so complicated that even Sherlock Holmes would feel helpless if it fell into his hands. [Now] it is solved by a woman who returned from abroad for a brief
visit to her hometown. Who is to say that the wisdom of Chinese cannot compete with the Westerners?”
The lead female detective in these stories, Chu Yi, is a fan of Doyle's Holmes stories and asks herself "What would Sherlock Holmes do?" while crime-solving, but succeeds through her use of martial arts and more "Chinese" attributes--China, not the West, solves the crimes.
Author Lü Simian, btw, is this guy: https://t.co/swPvAxr87J . One of the "four greatest modern Chinese historians," also wrote a landmark work of literary theory, and helped cohere Chinese detective fiction with his stories. Bit of a badass.
Holmes was the dominant influence on Chinese detective fiction of the late-Qing & early Republic years, and the biggest star of Chinese detective fiction of those years, Cheng Xiaoqing's Huo Sang, was a spin on Holmes.
- first Western detective stories translated & published in Japan in *1863*--that's pre-Meiji, even!
- first Chinese-written detective stories featuring Western-style detectives starred women as both detectives and criminals were published in 1907--author Lü Simian (!).
Quote: “This case is so complicated that even Sherlock Holmes would feel helpless if it fell into his hands. [Now] it is solved by a woman who returned from abroad for a brief
visit to her hometown. Who is to say that the wisdom of Chinese cannot compete with the Westerners?”
The lead female detective in these stories, Chu Yi, is a fan of Doyle's Holmes stories and asks herself "What would Sherlock Holmes do?" while crime-solving, but succeeds through her use of martial arts and more "Chinese" attributes--China, not the West, solves the crimes.
Author Lü Simian, btw, is this guy: https://t.co/swPvAxr87J . One of the "four greatest modern Chinese historians," also wrote a landmark work of literary theory, and helped cohere Chinese detective fiction with his stories. Bit of a badass.
Holmes was the dominant influence on Chinese detective fiction of the late-Qing & early Republic years, and the biggest star of Chinese detective fiction of those years, Cheng Xiaoqing's Huo Sang, was a spin on Holmes.
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@EricTopol @NBA @StephenKissler @yhgrad B.1.1.7 reveals clearly that SARS-CoV-2 is reverting to its original pre-outbreak condition, i.e. adapted to transgenic hACE2 mice (either Baric's BALB/c ones or others used at WIV labs during chimeric bat coronavirus experiments aimed at developing a pan betacoronavirus vaccine)
@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2
@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj
@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 30, 2021
"we generated a mouse model expressing hACE2 by using CRISPR/Cas9 knockin technology. In comparison with wild-type C57BL/6 mice, both young & aged hACE2 mice sustained high viral loads... pic.twitter.com/j94XtSkscj
@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2
1. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2!
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 2, 2021
2 papers:
Human\u2013viral molecular mimicryhttps://t.co/irfH0Zgrve
Molecular Mimicryhttps://t.co/yLQoUtfS6s https://t.co/lsCv2iMEQz
@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj

@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
