What does it take to sustain screwiness in the way the world works? Mostly, it's just good people, trying their best to get us to a better place... within constraints which pretty much preclude us actually getting anywhere! A case in point with
In one sentence, that's pretty much everything that's currently screwy with British PE 🤯
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Back in January, a news story was published about Kerrianne’s study showing improved social interaction outcomes for autistic adults when paired with another autistic partner.
A detailed thread about the study and a link to the paper can be found here (feel free to DM me your email address if you’d like a copy of the full paper for this study or any of our studies):
In our new paper out today, autistic adults held a \u201cget to know you\u201d conversation with an unfamiliar autistic or typically-developing (TD) person. We were curious: would social interaction outcomes differ when their partner was also autistic? THREAD https://t.co/4koqUKV9G1
— Noah Sasson (@Noahsasson) December 11, 2019
Another paper published early in 2020 (it appeared a few months earlier online) showed that traditional standalone tasks of social cognition are less predictive of functional and social skills among autistic adults than commonly assumed in autism research.
How well does social cognition predict functional and social skills in autism? Our new paper attempts to answer this question. This thread summarizes why we conducted the study, what we found, and why I think it\u2019s important. https://t.co/KB1nIpK0M2
— Noah Sasson (@Noahsasson) August 16, 2019
Next, @kmdebrabander led and published an innovative study about how well autistic and non-autistic adults can predict their own cognitive and social cognitive performance.
New by @kmdebrabander and our lab: Autistic adults don\u2019t differ from non-autistic adults in the accuracy of their self-assessment on general cognitive tasks but are less accurate on social cognitive tasks. This however was unrelated to social functioning https://t.co/0MrqMKKO0r
— Noah Sasson (@Noahsasson) September 20, 2020
Why can cefepime cause neurological toxicity?
And why is renal failure the main risk factor for this complication?
The answer requires us to learn about cefepime's structure and why it unexpectedly binds to a certain CNS receptor.
#MedTwitter #Tweetorial
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Let's establish a few facts about cefepime:
🔺4th generation cephalosporin antibiotic
🔺Excretion = exclusively in the urine (mostly as unchanged drug)
🔺Readily crosses the blood-brain barrier (so it easily accesses the brain)
https://t.co/rjYG1BfGPR
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The first report of cefepime neurotoxicity was in 1999.
A patient w/ renal failure received high doses of cefepime and then developed encephalopathy, tremors, myoclonic jerks, and tonic-clonic seizures.
✅All symptoms resolved after hemodialysis.
https://t.co/u7JLVitQpp
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Cefepime neurotoxicity is surprisingly common, occurring in up to 15% of treated critically ill patients (w/ symptoms varying from encephalopathy to seizures).
💡The main risk factors = renal failure and lack of dose adjustment for renal function.
https://t.co/nxbnzSq8AR
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What about cefepime induces neurotoxicity?
One clue is that it's not the only antibiotic that causes neurotoxicity, particularly seizures.
This actually is a class effect w/ other beta-lactam antibiotics (including penicillins and carbapenems).
https://t.co/Lf4BhON9IY
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Whenever we chant a Mantra in Sanskrit, it starts with 'Om' and mostly ends with 'Swaha' or 'Namaha'. This specific alignment of words has a specific meaning to it which is explained in Dharma Shastra.
Mantra is a Sanskrit word meaning sacred syllable or sacred word. But Mantras r not just words put together,they r also vibrations.The whole Universe is a cosmic energy in different states of vibration &this energy in different states of vibration forms the objects of Universe.
According to Scriptures,Om is considered to be ekaakshar Brahman,which means Om is the ruler of 3 properties of creator,preserver&destroyer which make the https://t.co/lyhkWeCdtv is also seen as a symbol of Lord Ganesha, as when starting the prayer,it's him who is worshipped 1st.
'Om' is the sound of the Universe. It's the first original vibration of the nothingness through which manifested the whole Cosmos. It represents the birth, death and rebirth process. Chanting 'Om' brings us into harmonic resonance with the Universe. It is a scientific fact.
Therefore, Mantras are described as vibrational words that are recited, spoken or sung and are invoked towards attaining some very specific results. They make very specific sounds at a frequency that conveys a directive into our subconcious.