I never wanted to write a Prof thread here since I wanted this to be break.
But some comments regarding Dentistry is pushing me to be writing this, making me do what I have been trying to explain to people for a long time.
#Thread
#Dentistry
1)

Oral health has been the least concern of people in India. A Dentist is only sought after in case of emergency or when a certificate is needed. Making it a 2nd tier speciality.
However it can't be further from the truth.
This is about Dentistry & it's relation to Gen health
2
Heart:
Since someone commented teeth can't stop heart!
Well! It can
Sub acute endocarditis
Species of Streptococci that live on the teeth, gums& related structures, get mobilized into blood stream when the load of infection increases
If a patient has a valve defect or
3
Previous surgery, these bacteria colonize & cause blockage that is slow & fatal.
Also untreated dental infection can cause the failure of any Cardiac procedure performed.
Hence it's advised to get teeth treated before a cardiac surgery.

Brain:
Teeth have lymph drainage
4
Into a Sinus called Cavernous sinus. That's also connected to brain.
Untreated dental infection can lead to abscess in brain, causing epilepsy like seizures & de@th if not treated.
Seen a 6 yr old boy losing life bcoz of it since Doctor could not trace the source of infection
5
Kidney:
E. Coli most common pathogen in kidney failure is a resident of Gum, periodontal abcess.
Usually when bacterial load increases, the mobilization of bacteria in blood targets the most vulnerable organ in body
So for a Diabetic patient it would kidney or bladder,can stop
6
Functioning of organ

Ear:
Ear has a tube connecting it to side of the tooth in upper jaw.
It's called Eustachian tube
If a child is left after feeding, without cleaning the mouth for residual milk or untreated dental infection in that area, causes Ear infection.
At times
7
Partial loss of hearing

I forgot earlier untreated Dental infection increases risk of Diabetes with age, & viceversa

Pregnancy :
Now this aspect is most important.
Hormonal changes in pregnancy also control the health of gums.
So similarly, infection in gums can cause
8
Irregular hormones for pregnancy.
It can lead to low birth weight of the baby or even miscarriage. Difficulty in conception also results with prolonged Infection of gums.

Mother also transfers her anti body to baby through placenta & milk.
Bacterial load between mom & child
9
Are also similar to the level of sane gene coding
Hence mother with more dental problems have children with high caries risk.

Back ache:
Improper filling, crown or bite leads to improper posturing of the next.
That with age gets shifted to lower back.
Many people keep
10
Getting physiotherapy done with no use as its bcoz of the jaw.

Similarly there is something called
Myofunctional pain Dysfunction Syndrome
Or MPDS

It too mimics Migraine
The reason is same, faulty occlusion.

I can go on & on.
But I want this to be shared hence shortening
11
Lastly expertise of ur Dentist:
A faulty RCT or extraction or a broken file in ur tooth can cause any of the problems above, or some more.
It can even be fatal like air embolism caused due to wrong irrigants

Hence plz dont take Oral health lightly.
It's more important
12
In case of children, Pregnant women and Patient with special healthcare needs.
Always consult the specialist with proper Sterilization protocols as Dental operatory can transfer HIV, to Hepatitis to Corona
Plz share with ur friends and family 🙏
13

*End*

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1/16
Why do B12 and folate deficiencies lead to HUGE red blood cells?

And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?

For answers, we'll have to go back a few billion years.


2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.

Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine

But why does DNA contains thymine (T) instead of uracil (U)?

https://t.co/XlxT6cLLXg


3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).

In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?

https://t.co/bIZGviHBUc


4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.

DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.

https://t.co/bIZGviHBUc


5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.

When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.

[*Note: thymine is the base in dTMP]

https://t.co/AnDUtKkbZh
I think @SamAdlerBell in his quest to be the contrarian on Fauci gets several things wrong here. 1/


First, the failure last year actually was driven by the White House, the #Trump inner circle. Watch what's happening now, the US' scientific and public health infrastructure is creaking back to life. 2/

I think Sam underestimates the decimation of many of our health agencies over the past four years and the establishment of ideological control over them during the pandemic. 3/

I also am puzzled why Tony gets the blame for not speaking up, etc. Robert Redfield, Brett Giroir, Deb Birx, Jerome Adams, Alex Azar all could have done the same. 4/

Several of these people Bob Redfield, Brett Giroir, Alex Azar were led by craven ambition, Jerome Adams by cowardice, but I do think Deb Birx and Tony tried as institutionalists, insiders to make a difference. 5/

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