Cartoon Review Of The Year (Thread)
I'm just a cartoonist. What the hell do I know?
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Dream & friends' (@GeorgeNotFound, @tommyinnit, @Quackity, @TubboLive, @WilburSoot, etc) meteoric rise and the massive return of Minecraft has been one of the most amazing gaming stories this year.
1 mil to 15 mil in one year. INSANE. thank you guys so much. have completely changed my life.
— Dream (@Dream) December 30, 2020
1/ What do Dream and crew get so right?
On the surface, it's clear that they show the power of good storytelling and each of our desires to "hang out" with a group of friends that are having fun.
(image @Animagician_)
2/ This remains one of, if not the most important draws for great parasocial content -- whether it be Seinfeld, @DavidDobrik's vlogs, or Dream SMP content, the same is true:
We want to feel a little less alone and spend time in the worlds of these friends we know so much about.
3/ Watching this new wave of superstars take over YouTube / Twitch / Twitter gaming cultures has been incredible and bizarre.
Check the replies and engagement
:)
— Dream (@Dream) November 30, 2020
4/ Dream speaks to the underrated and remarkable nature of Minecraft, too. In its 9th year, the game continues to dominate. Why?
Accessible, multi-platform, wide appeal? Sure - but more importantly: it is infinitely extendable. It's a creator's perfect sandbox. (image @SipoverS)
There\u2019s a lotta pain coming my friend
— \U0001f339\u269c\ufe0f \u2694\ufe0f\U0001d4ae\U0001d4bd\U0001d452\U0001d4c0\U0001d4bd\U0001d4be\U0001d4c3\U0001d4b6\U0001d4bd \u2694\ufe0f \u269c\ufe0f \U0001f339 (@PetahJane) November 29, 2020
Ts 3:32 29.11.2920
33 22 9 11 22
33 22<911>22
\U0001f446 seen this pattern 3 times now
33 > Christ
22 > Balance
911 > Jesus birthday
22 > Balance
The message here: Christ will return and when he does, the balance lost is restored \U0001f64f\U0001f3fb\u2764\ufe0f
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@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 30, 2021
"we generated a mouse model expressing hACE2 by using CRISPR/Cas9 knockin technology. In comparison with wild-type C57BL/6 mice, both young & aged hACE2 mice sustained high viral loads... pic.twitter.com/j94XtSkscj
@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2
1. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2!
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 2, 2021
2 papers:
Human\u2013viral molecular mimicryhttps://t.co/irfH0Zgrve
Molecular Mimicryhttps://t.co/yLQoUtfS6s https://t.co/lsCv2iMEQz
@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj
@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
Some random interesting tidbits:
1) Zuck approves shutting down platform API access for Twitter's when Vine is released #competition
2) Facebook engineered ways to access user's call history w/o alerting users:
Team considered access to call history considered 'high PR risk' but 'growth team will charge ahead'. @Facebook created upgrade path to access data w/o subjecting users to Android permissions dialogue.
3) The above also confirms @kashhill and other's suspicion that call history was used to improve PYMK (People You May Know) suggestions and newsfeed rankings.
4) Docs also shed more light into @dseetharaman's story on @Facebook monitoring users' @Onavo VPN activity to determine what competitors to mimic or acquire in 2013.
https://t.co/PwiRIL3v9x