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Where antibiotic resistance comes from

https://t.co/CULwpxEVBJ

#antibiotics #resistance #genomes #EvolutionaryHistory

Along with vaccine rollouts, the U.S. needs a National Hi-Fi Mask Initiative

https://t.co/oqInlLSJl2

#PandemicResponse #vaccines #masks #COVID19
SCIENCE

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Roland Baker
Roland Baker
@RolandBakerIII
Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD. This is a plain English Description of the code:
https://t.co/w7koHyMJjL

The article mentions a “10 nucleotide linker” (GCAUAUGACU) in the poly-A tail. This is described in the patent link below (Modification of RNA, producing an increased transcript stability and translation

Here is a link to the full mRNA code if you wish to download it, blast it or make up a batch in your garage


An overview of the encoded spike


Initial mouse
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Operation Cupcake
Operation Cupcake
@PhillipsBarrie
Wow, Morgan McSweeney again, Rachel Riley, SFFN, Center for Countering Digital Hate, Imran Ahmed, JLM, BoD, Angela Eagle, Tracy-Ann Oberman, Lisa Nandy, Steve Reed, Jon Cruddas, Trevor Chinn, Martin Taylor, Lord Ian Austin and Mark Lewis. #LabourLeaks #StarmerOut 24 tweet🧵

Morgan McSweeney, Keir Starmer’s chief of staff, launched the organisation that now runs SFFN.
The CEO Imran Ahmed worked closely with a number of Labour figures involved in the campaign to remove Jeremy as leader.

Rachel Riley is listed as patron. https://t.co/nGY5QrwBD0


SFFN claims that it has been “a project of the Center For Countering Digital Hate” since 4 May 2020. The relationship between the two organisations, however, appears to date back far longer. And crucially, CCDH is linked to a number of figures on the Labour right. #LabourLeaks

Center for Countering Digital Hate registered at Companies House on 19 Oct 2018, the organisation’s only director was Morgan McSweeney – Labour leader Keir Starmer’s chief of staff. McSweeney was also the campaign manager for Liz Kendall’s leadership bid. #LabourLeaks #StarmerOut

Sir Keir - along with his chief of staff, Morgan McSweeney - held his first meeting with the Jewish Labour Movement (JLM). Deliberately used the “anti-Semitism” crisis as a pretext to vilify and then expel a leading pro-Corbyn activist in Brighton and Hove
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jeevan patwa
jeevan patwa
@jeevanpatwa
#SuvenLife – Niche R&D play..very high risk and very high reward…key is right allocation…

Jazz Pharma was quoting around $0.5 in 2009, today its $150 and Mcap of $8.5 Bn on Nasdaq..almost 300x in 11 years. 80% of its total sales ($2.1 Bn) come from single drug Xyrem.

Axovant Lifescience, bought Alzheimer molecule from GSK, repackaged it and done phase-3 trials. Before starting the trials, the valuation was $2 Bn, just before announcing the data, it rose to $3 Bn. One of the leading broker put the target of $12 Bn if the trials succeeded..

but it failed in phase-3 trials. Current Mcap is $120 Mn…

This is R&D for New Chemical Entity (NCE)…very high risk and very high reward…

Brain-related illnesses, also known as CNS diseases, afflict more than 2 billion people worldwide. Diseases of the brain and mind range

from Alzheimer’s, dementia, epilepsy, migraine, multiple sclerosis, neuro infections, Parkinson’s, psychosis, schizophrenia and stroke to brain injuries and various mental disorders. The global market or CNS therapeutics is projected to reach $137.7 billion by 2025.

#SuvenLife has 1 lead molecule SUVN-G3031 in phase-2 trials which is similar to Xyrem but superior features, 3 molecules completed phase-1 trials and starting phase-2 trials and 11 molecules in pre-clinical trials. All are related to CNS which is growing and uncluttered market
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SALTSTORM007
SALTSTORM007
@saltstorm007
Ok...just spent a few looking at The Weekend’s page and it is weird AF!!! First off is this banner pic he has...take a look at it...a CLOSE LOOK AT IT....see all the ‘strange’ images he has within it? Notice the dice...all the 6’s...serpent tongue....
NOTHING TO SEE HERE.👇thread
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Emily\u2661
Emily♡
@ItsEmilyKaty
To the person who thinks that they might be autistic. - a thread. /1

I imagine you have gone your entire life wondering why you are different, why you can't seem to understand things the way that others can and why everything just seems so hard. I'm proud of you for getting this far. /2

Part of you might be thinking:
"But if I was autistic, surely it would've been noticed when I was a kid? So maybe I'm making this up."
So many autistic people aren't diagnosed until they are adults, if diagnosed at all. You would not be the first and you won't be the last. /3

"My family and friends don't think that I could be autistic."
People's understandings of autism tend to be based off of the media, which doesn't show every possible presentation of autism, or based off of someone they know, and all autistic people present differently. /4

People's perceptions of autism can also be based off stereotypes, for example, "autistic people can't make eye contact, so you can't be autistic." While this is true for some, it isn't for all, so you can begin to see how one presentation of autism can't possibly fit everyone. /5
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Vibhu Vashisth
Vibhu Vashisth
@VIBHU_Tweet
ANCIENT BHARAT WAS CALLED VISHWAGURU, AND IT REALLY DESERVED IT.

India had a well developed education system centuries before the westerners arrived and called us uncivilized. Education was always given a great importance in Indian civilisation since times immemorial.


Ancient India had the Gurukulas and Ashramas as the epicentres of the knowledge and enlightenment. Bigger Gurukulas served as the centres of higher education called universities. Besides these universities, temples also emerged as the major learning centres.

Studying the Holy Scriptures, character building, personality development, responsibilities towards self,family and society,discipline and preservation of the ancient culture and heritage were the key embodiments of education.

This kind of education system made ancient India, a centre of knowledge all over the world. Many foreign students came to India for education and India was called the 'Vishwaguru'.
Takshshila and Nalanda were the two prominent universities of ancient India.


But were these only Universities of ancient India?The answer is 'No'.Let's learn about these gems of our education system that flourished across ancient India & be proud.

NALANDA UNIVERSITY
This was the oldest university of ancient India.Situated in Nalanda distt. of Bihar...
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Jaya_Upadhyaya
Jaya_Upadhyaya
@Jayalko1
HORANADU ANNAPOORNESHWARI, CHIKMAGALUR (KAR)
#bharatmandir

Annapoorneshwari is the Devi of nutrition and food. The literal meaning of Annapoorneshwari is “Feeding one and all”. Anyone who comes here is offered meals and shelter within the premises.
@LostTemple7


Maharshi Agastya is believed to have done pratishtha here.

Once, Shiva and Parvati had an argument. Shiva declared everything in the world including food to be Maya or illusion. To prove him wrong, Devi Parvati disappeared resulting in entire Earth becoming still.


Taking pity, Devi appeared as Annapoorna and relieved everyone.
Another belief is that once Shiva beheaded Brahma and his skull got stuck in Shiva’s hand. He was cursed that till the skull is not full of food or grains, it will remain stuck to his hands.


Shiva went everywhere and asked for food but the skull was never full. He finally came here and Maa Annapoorna filled the skull with grains and reversed Shiva’s curse.

It is believed that who ever visits Devi Annapoorna here will never be without food in their lives.
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Marina Amaral
Marina Amaral
@marinamaral2
Rio de Janeiro, 1920. 🇧🇷


São Paulo, 1910. 🇧🇷


“Arpoador”, Rio de Janeiro, 1900. 🇧🇷


“Avenida Paulista”, São Paulo, 1902. 🇧🇷


Recife, 1885. 🇧🇷
HISTORY
Peggy Klaver #FBR \U0001f30a\u270a\U0001f3fb\u270a\U0001f3fd\u270a\U0001f3ff\u270a\U0001f3fc
Peggy Klaver #FBR 🌊✊🏻✊...
@Pegerella
The man who invented autocorrect should burn in hello.

It was meant to put a smile on your face. Please stop sending me instructions on how to turn my autocorrect off. 😳🤔

Texted my friends to ask if I could take their kids with me to Satan... still have not heard back from them. I meant Santa...

Thanks for all the love, I appreciate a follow. 💗
FUN
Greg Olear
Greg Olear
@gregolear
Trump is a Russian asset, a mob money launderer installed by his mob whoremasters to sow chaos and weaken the US & our allies.

EVERY SINGLE THING HE’S DONE since taking office is to achieve those purposes—that and to enrich himself personally.

[THREAD]


1/ His entire family is part of this. Melania is a fucking crook. Ivanka is a fucking crook. Junior and Gums are fucking crooks. They will all die in prison, except for Kushner, who, if he really *did* trade US intel for money, should be executed for espionage.

2/ Why do you think Trump installs uniquely corrupt & awful people to Cabinet positions? Pruitt, Zinke, Betsy, Rex/Pompeo, Wilbur "Melting Nazi Face" Ross. They are not there to serve us. They are not there to drain the swamp. They are there to BURN THE REPUBLIC DOWN.

3/ Trump steals. He takes taxpayer money—your money and mine—and lines his pockets with it. He exploits his office to make himself richer. This is all he cares about. Why are Republican citizens, you “fiscal conservatives,” not more angry about this? Riddle me THAT, #MAGA.

4/ Matt Whitaker, the human dildo and “acting AG,” was illegally installed to throw a monkey wrench in the Mueller investigation. That’s why they won’t release his financials. He’s fucking bought and sold. He’s going to prison for obstruction.
POLITICS