Reasons not to do it

Let me talk about something
I consider myself qualified to discuss: a film director, Oliver Stone. OS is a great political director & a very clever man, one of the best in the industry. My view is that he did not simply take the Russian vx because he didn't want to wait for US 1

He's a very clever man, he made a judgement for his own life, for his family, & he chose the Russian vx instead of any of the Western ones, because he wanted the vx & considers Sputnik V the safest one.

I can see the logic:
1 No accountability for any of the Western vx, nobody can sue for any damage etc.
2 Those who made Sputnik V know they are always personally accountable to Vladimir Putin
3 S5 is based on a pre-existing vx with minimal changes so safety tried for many years

So if the Russians could find a safe way to adapt a tried & tested technology & only alter what is required, using adenovirus vectors, a technology in use for 50 years, experimented on for vx since the 1980s, why were Western Big Pharma so keen on something completely new: mRNA?

That is the question that Oliver Stone is indirectly asking us all to look into & answer: why were Western Big Pharma all at once suddenly so keen on using mRNA when there were much safer & tested directions available (adenovirus vectors), what is it that Western Big Pharma want?

I'm going to attempt to chronologically list all of the Marvel characters Stan Lee had a hand in creating. Working with his genius collaborators, Stan and his team produced an insane amount of iconic characters in a roughy ten year period. (Thread)

With his younger brother, writer Larry Lieber, and Jack "the King" Kirby:

Groot

Tales to Astonish #13 (November, 1960)

With writer Lieber, and artist Kirby:

Fin Fang Foom

Strange Tales #89 (October, 1961)

With the King, Stan gives birth to the Marvel Universe:

The Fantastic Four

Fantastic Four #1 (November, 1961)

With Jack Kirby:

Mister Fantastic

Fantastic Four #1 (November, 1961)

I have decided to take a dive into the d20 System era, so today’s game is its starting point, Dungeons & Dragons Third Edition (2000) from Wizards of the Coast. I worked at WotC from 1998 to 2002 so I was there for the development, launch, and follow-up to 3E. #CuratedQuarantine

I did no design work on the core game, but I was in roleplaying R&D, so I was involved in the internal playtesting, meetings, and discussions. Everyone involved in 3E got a Player’s Handbook with their name embossed on the front cover. The pictures show mine. #CuratedQuarantine

Now AD&D Second Edition had been published in 1989 and WotC bought the ailing TSR in 1997, so it made sense to do a new edition. The goal was to retain the core of D&D but to rationalize the rules to make them more consistent & ideally easier to learn and play. #CuratedQuarantine

In previous editions, sometimes you wanted to roll high and sometimes you wanted to roll low. Sometimes you rolled a d20 and sometimes percentile dice. A lower armor class was better than a higher one, with the result that +3 armor actually reduced your AC. #CuratedQuarantine

This is the sort of stuff that 3E addressed successfully. There was a core mechanic for everything. Roll a d20, add modifiers, and try to hit a target number (hence the d20 System). #CuratedQuarantine