Thread 1: https://t.co/5WN9StpFZT
Masks increase mortality because breathing through them nebulizes aerosols into smaller ones which bypass mucosal immunity & reach all the way into the alveoli, leading to acute respiratory distress syndrome (ARDS).
"Aerosols..within the most breathable size range between 0.5 & 5 μm, can carry SARS-CoV-2 deep to the terminal alveoli..if this transmission pathway does exist, it would bypass the mucociliary clearance & incubation period of the virus in the upper airways
https://t.co/vjcinmtiHT
The filtration material itself of N95's average pore size ~0.3āˆ’0.5 μm does not block finer aerosol laden with virions penetration, not to mention surgical masks.
THE NOSE: "Particles larger than 3μm have a maximum deposition in the anterior part of the nose (nasal valve). Particles smaller than 3μm & larger than 0.5μm are filtered by the nasal mucosa and transported by cilia propulsion to the nasopharynx."
THE N95 MASK: The filtration material itself of N95's average pore size ~0.3āˆ’0.5 μm [larger average pore size is just like the human NOSE] does not block finer aerosol laden with virions penetration, not to mention surgical masks. For example, see Balazy et al. (2006).
THE NOSE is as good a filter as an N95 mask given the many pores which are equal in size to the filtration capacity of the nose of 0.5μm. HOWEVER breathing mouth to mask NEBULIZES aerosols making them more infectious to other people's lung alveoli.
https://t.co/oIf7N6f9Yz
There are in fact products that nebulize in order to get smaller aerosols into the lungs: https://t.co/JDGcoNJjZN
How masks nebulize: https://t.co/vccxMx3AQr
Masks may increase mortality because breathing through them can nebulize aerosols into smaller ones which bypass mucosal immunity & reach all the way into the alveoli, leading to acute respiratory distress syndrome (ARDS)
https://t.co/vjcinmtiHT
ARDS is a Covod19 mortality route https://t.co/GuE9QAeqDF
Thread 2: https://t.co/sMFPnrlON3
Conclusion: you want to keep the aerosols as BIG as possible. Masks nebulize them as they squeeze them through a filter. Best public health option is no masks & breathe through nose https://t.co/xXRUnRAR1l

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